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BioLiP
Download all results in tab-seperated text for 36 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 2vmf:A (2.1) BS01 MVL 3.2.1.25 GO:0004553 ... Q8AAK6 18408714 MOAD: Ki=1400nM
    PDBbind: -logKd/Ki=5.85, Kd=1400nM
    BindingDB: Ki=1400nM
    2 2vmf:B (2.1) BS01 MVL 3.2.1.25 GO:0004553 ... Q8AAK6 18408714 MOAD: Ki=1400nM
    BindingDB: Ki=1400nM
    3 2wzs:A (2.25) BS02 MVL ? GO:0000224 ... Q8A0N1 20081828 MOAD: Ki=140uM
    PDBbind: -logKd/Ki=3.85, Ki=140uM
    4 2wzs:B (2.25) BS02 MVL ? GO:0000224 ... Q8A0N1 20081828 MOAD: Ki=140uM
    5 2wzs:C (2.25) BS02 MVL ? GO:0000224 ... Q8A0N1 20081828 MOAD: Ki=140uM
    6 2wzs:D (2.25) BS02 MVL ? GO:0000224 ... Q8A0N1 20081828 MOAD: Ki=140uM
    7 2wzs:E (2.25) BS02 MVL ? GO:0000224 ... Q8A0N1 20081828 MOAD: Ki=140uM
    8 2wzs:F (2.25) BS02 MVL ? GO:0000224 ... Q8A0N1 20081828 MOAD: Ki=140uM
    9 2wzs:G (2.25) BS02 MVL ? GO:0000224 ... Q8A0N1 20081828 MOAD: Ki=140uM
    10 2wzs:H (2.25) BS02 MVL ? GO:0000224 ... Q8A0N1 20081828 MOAD: Ki=140uM
    11 3d4y:A (1.52) BS02 MVL 3.2.1.114 GO:0000139 ... Q24451 18759458 MOAD: Ki=2uM
    PDBbind: -logKd/Ki=5.70, Ki=2uM
    12 4ayq:A (1.1) BS01 MVL 3.2.1.113 GO:0004559 ... B0SWV2 23012075 MOAD: Kd=47nM
    PDBbind: -logKd/Ki=7.33, Kd=47nM
    13 4cd5:A (1.1) BS02 MVL 3.2.1.78 GO:0004553 ... B3PGI1 24339341 PDBbind: -logKd/Ki=6.71, Ki=194nM
    14 4cd8:A (1.47) BS01 MVL 3.2.1.78 N/A A5H1I6 24339341 PDBbind: -logKd/Ki=2.89, Ki=1.3mM
    15 4re2:A (2.0) BS01 MVL 3.2.1.25 GO:0004553 ... A2YPH1 N/A PDBbind: -logKd/Ki=4.98, Ki=10.4uM
    16 6f90:A (2.4) BS02 MVL ? GO:0005975 ... Q8A325 29717710 PDBbind: -logKd/Ki=6.00, Ki=1.0uM
    17 6f90:B (2.4) BS02 MVL ? GO:0005975 ... Q8A325 29717710
    18 6f90:C (2.4) BS02 MVL ? GO:0005975 ... Q8A325 29717710
    19 6f92:A (1.9) BS02 MVL ? GO:0000224 ... Q8A0Q6 29717710 PDBbind: -logKd/Ki=6.40, Ki=0.4uM
    20 6f92:B (1.9) BS02 MVL ? GO:0000224 ... Q8A0Q6 29717710
    21 6f92:C (1.9) BS02 MVL ? GO:0000224 ... Q8A0Q6 29717710
    22 6f92:D (1.9) BS02 MVL ? GO:0000224 ... Q8A0Q6 29717710 PDBbind: -logKd/Ki=6.40, Ki=0.4uM
    23 6far:A (1.3) BS02 MVL ? GO:0004559 ... D6D1V7 29508463
    24 6rqk:A (1.85) BS01 MVL ? GO:0005975 ... Q8XNB2 31407758 MOAD: Kd=1.6mM
    PDBbind: -logKd/Ki=2.80, Kd=1.6mM
    25 6rqk:A (1.85) BS02 MVL ? GO:0005975 ... Q8XNB2 31407758 MOAD: Kd=1.6mM
    PDBbind: -logKd/Ki=2.80, Kd=1.6mM
    26 6rqk:B (1.85) BS01 MVL ? GO:0005975 ... Q8XNB2 31407758 MOAD: Kd=1.6mM
    27 6rqk:B (1.85) BS02 MVL ? GO:0005975 ... Q8XNB2 31407758 MOAD: Kd=1.6mM
    28 6t7g:AAA (1.8) BS01 MVL ? GO:0004565 ... I9SUA3 31871050
    29 6t7g:BBB (1.8) BS01 MVL ? GO:0004565 ... I9SUA3 31871050
    30 6t7g:CCC (1.8) BS01 MVL ? GO:0004565 ... I9SUA3 31871050
    31 6t7g:DDD (1.8) BS01 MVL ? GO:0004565 ... I9SUA3 31871050
    32 6t7g:EEE (1.8) BS01 MVL ? GO:0004565 ... I9SUA3 31871050
    33 6t7g:FFF (1.8) BS01 MVL ? GO:0004565 ... I9SUA3 31871050
    34 7nsn:A (2.29) BS05 MVL 3.2.1.- GO:0005975 ... A0A7R9KAR8 37071393
    35 7nsn:A (2.29) BS07 MVL 3.2.1.- GO:0005975 ... A0A7R9KAR8 37071393
    36 7nsn:B (2.29) BS05 MVL 3.2.1.- GO:0005975 ... A0A7R9KAR8 37071393
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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