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BioLiP
Download all results in tab-seperated text for 12 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 2vta:A (2.0) BS01 LZ1 2.7.11.22 GO:0000082 ... P24941 18656911 MOAD: ic50=185uM
    PDBbind: -logKd/Ki=3.73, IC50=185uM
    BindingDB: IC50=185000nM
    2 3e6i:A (2.2) BS02 LZ1 1.14.13.n7
    1.14.14.1    		 GO:0001676 ... P05181 18818195
    3 3e6i:B (2.2) BS02 LZ1 1.14.13.n7
    1.14.14.1    		 GO:0001676 ... P05181 18818195
    4 4b2i:A (1.3) BS01 LZ1 ? GO:0003677 ... O74036 23344974 MOAD: Kd=1mM
    PDBbind: -logKd/Ki=3.00, Kd=1.0mM
    BindingDB: Kd=1000000nM
    5 5lk9:A (1.12) BS02 LZ1 ? GO:0004601 ... Q9NAV7 N/A
    6 5lk9:B (1.12) BS02 LZ1 ? GO:0004601 ... Q9NAV7 N/A
    7 5qur:A (1.247) BS01 LZ1 ? GO:0003677 ... O74036 N/A BindingDB: Kd=1000000nM
    8 5qus:A (1.247) BS01 LZ1 ? GO:0003677 ... O74036 N/A BindingDB: Kd=1000000nM
    9 5qut:A (1.248) BS01 LZ1 ? GO:0003677 ... O74036 N/A BindingDB: Kd=1000000nM
    10 7h97:A (1.54) BS01 LZ1 2.1.1.-
    2.7.7.-
    2.7.7.19
    2.7.7.48
    3.1.3.84
    3.4.22.-
    3.6.1.15
    3.6.1.74
    3.6.4.13    		 N/A Q8JUX6 N/A
    11 7h97:D (1.54) BS01 LZ1 2.1.1.-
    2.7.7.-
    2.7.7.19
    2.7.7.48
    3.1.3.84
    3.4.22.-
    3.6.1.15
    3.6.1.74
    3.6.4.13    		 N/A Q8JUX6 N/A
    12 7o6r:A (2.0) BS01 LZ1 3.6.4.10 GO:0005524 ... P19120 38317495
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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