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BioLiP
Download all results in tab-seperated text for 13 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 3ti3:A (1.8) BS03 LNV 3.2.1.18 GO:0004308 ... C3W5S3 22028647 MOAD: ic50=1.83nM
    PDBbind: -logKd/Ki=8.74, IC50=1.83nM
    2 3ti3:B (1.8) BS03 LNV 3.2.1.18 GO:0004308 ... C3W5S3 22028647 MOAD: ic50=1.83nM
    3 3ti8:A (1.601) BS02 LNV 3.2.1.18 GO:0004308 ... A1ILL9 22028647 MOAD: ic50=0.9nM
    PDBbind: -logKd/Ki=9.05, IC50=0.90nM
    4 3ti8:B (1.601) BS02 LNV 3.2.1.18 GO:0004308 ... A1ILL9 22028647 MOAD: ic50=0.9nM
    5 3tia:A (1.8) BS04 LNV 3.2.1.18 GO:0004308 ... Q194T1 22028647 MOAD: ic50=3.12nM
    PDBbind: -logKd/Ki=8.51, IC50=3.12nM
    BindingDB: IC50=3100nM
    6 3tia:B (1.8) BS04 LNV 3.2.1.18 GO:0004308 ... Q194T1 22028647 MOAD: ic50=3.12nM
    BindingDB: IC50=3100nM
    7 3tia:C (1.8) BS04 LNV 3.2.1.18 GO:0004308 ... Q194T1 22028647 MOAD: ic50=3.12nM
    BindingDB: IC50=3100nM
    8 3tia:D (1.8) BS04 LNV 3.2.1.18 GO:0004308 ... Q194T1 22028647 MOAD: ic50=3.12nM
    BindingDB: IC50=3100nM
    9 4hzw:A (1.701) BS02 LNV 3.2.1.18 GO:0004308 ... A9YN63 23824808 MOAD: ic50=1.31nM
    PDBbind: -logKd/Ki=8.88, IC50=1.31nM
    10 4mwu:A (1.799) BS02 LNV 3.2.1.18 GO:0004308 ... A0A024E3Q2 24165891 MOAD: ic50=3.24nM
    PDBbind: -logKd/Ki=8.49, IC50=3.24nM
    11 4mwy:A (1.8) BS02 LNV 3.2.1.18 GO:0004308 ... A0A067Y7N7 24165891 MOAD: ic50=89.6nM
    PDBbind: -logKd/Ki=7.05, IC50=89.6nM
    12 4qn6:A (1.945) BS02 LNV 3.2.1.18 GO:0004308 ... Q2FCL6 24899180
    13 4qn6:B (1.945) BS02 LNV 3.2.1.18 GO:0004308 ... Q2FCL6 24899180
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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