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BioLiP
Download all results in tab-seperated text for 9 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1fo3:A (1.75) BS01 KIF 3.2.1.113 GO:0004571 ... Q9UKM7 10995765 MOAD: ic50=0.2uM
    PDBbind: -logKd/Ki=6.70, IC50=0.2uM
    2 1krf:A (2.2) BS02 KIF 3.2.1.113 GO:0004571 ... P31723 11714724
    3 1krf:B (2.2) BS02 KIF 3.2.1.113 GO:0004571 ... P31723 11714724
    4 1ps3:A (1.8) BS02 KIF 3.2.1.114 GO:0000139 ... Q24451 14636047 MOAD: Ki=5.2mM
    PDBbind: -logKd/Ki=2.28, Ki=5.2mM
    5 2wvz:A (2.4) BS02 KIF ? GO:0000224 ... Q8A0N1 20081828 MOAD: Ki=96uM
    PDBbind: -logKd/Ki=4.02, Ki=96uM
    6 2wvz:B (2.4) BS02 KIF ? GO:0000224 ... Q8A0N1 20081828 MOAD: Ki=96uM
    7 2wvz:C (2.4) BS02 KIF ? GO:0000224 ... Q8A0N1 20081828 MOAD: Ki=96uM
    8 2wvz:D (2.4) BS02 KIF ? GO:0000224 ... Q8A0N1 20081828 MOAD: Ki=96uM
    9 5ne5:A (1.05) BS01 KIF 3.2.1.113 GO:0004559 ... B0SWV2 28493500 MOAD: Kd=39nM
    PDBbind: -logKd/Ki=7.41, Kd=39nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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