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BioLiP
Download all results in tab-seperated text for 38 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 3phb:E (2.3) BS01 IM5 2.4.2.1 GO:0000255 ... P00491 N/A BindingDB: Ki=7nM
    2 3phb:Q (2.3) BS01 IM5 2.4.2.1 GO:0000255 ... P00491 N/A BindingDB: Ki=7nM
    3 3phb:S (2.3) BS01 IM5 2.4.2.1 GO:0000255 ... P00491 N/A BindingDB: Ki=7nM
    4 3phb:T (2.3) BS01 IM5 2.4.2.1 GO:0000255 ... P00491 N/A BindingDB: Ki=7nM
    5 3phb:U (2.3) BS01 IM5 2.4.2.1 GO:0000255 ... P00491 N/A BindingDB: Ki=7nM
    6 3phb:Y (2.3) BS01 IM5 2.4.2.1 GO:0000255 ... P00491 N/A BindingDB: Ki=7nM
    7 3phc:A (2.0) BS01 IM5 2.4.2.1
    2.4.2.44    		 GO:0003824 ... Q8I3X4 N/A
    8 3phc:B (2.0) BS01 IM5 2.4.2.1
    2.4.2.44    		 GO:0003824 ... Q8I3X4 N/A
    9 3phc:C (2.0) BS01 IM5 2.4.2.1
    2.4.2.44    		 GO:0003824 ... Q8I3X4 N/A
    10 3phc:D (2.0) BS01 IM5 2.4.2.1
    2.4.2.44    		 GO:0003824 ... Q8I3X4 N/A
    11 3phc:E (2.0) BS01 IM5 2.4.2.1
    2.4.2.44    		 GO:0003824 ... Q8I3X4 N/A
    12 3phc:F (2.0) BS01 IM5 2.4.2.1
    2.4.2.44    		 GO:0003824 ... Q8I3X4 N/A
    13 4ear:A (1.7) BS01 IM5 2.4.2.1 GO:0000255 ... P00491 23438750 PDBbind: -logKd/Ki=9.82, Kd=151pM
    BindingDB: Ki=7nM
    14 4ear:B (1.7) BS01 IM5 2.4.2.1 GO:0000255 ... P00491 23438750 BindingDB: Ki=7nM
    15 4ear:C (1.7) BS01 IM5 2.4.2.1 GO:0000255 ... P00491 23438750 PDBbind: -logKd/Ki=9.82, Kd=151pM
    BindingDB: Ki=7nM
    16 4eb8:A (2.3) BS02 IM5 2.4.2.1 GO:0000255 ... P00491 23438750 PDBbind: -logKd/Ki=9.82, Ki=151pM
    BindingDB: Ki=7nM
    17 4eb8:B (2.3) BS02 IM5 2.4.2.1 GO:0000255 ... P00491 23438750 BindingDB: Ki=7nM
    18 4eb8:C (2.3) BS02 IM5 2.4.2.1 GO:0000255 ... P00491 23438750 PDBbind: -logKd/Ki=9.82, Ki=151pM
    BindingDB: Ki=7nM
    19 5etj:A (2.3) BS01 IM5 2.4.2.1 GO:0000255 ... P00491 26927977 MOAD: Kd=66pM
    PDBbind: -logKd/Ki=10.18, Ki=66pM
    BindingDB: Ki=7nM
    20 5etj:B (2.3) BS01 IM5 2.4.2.1 GO:0000255 ... P00491 26927977 MOAD: Kd=66pM
    PDBbind: -logKd/Ki=10.18, Ki=66pM
    BindingDB: Ki=7nM
    21 5etj:C (2.3) BS01 IM5 2.4.2.1 GO:0000255 ... P00491 26927977 MOAD: Kd=66pM
    BindingDB: Ki=7nM
    22 5etj:D (2.3) BS01 IM5 2.4.2.1 GO:0000255 ... P00491 26927977 MOAD: Kd=66pM
    BindingDB: Ki=7nM
    23 5etj:E (2.3) BS01 IM5 2.4.2.1 GO:0000255 ... P00491 26927977 MOAD: Kd=66pM
    BindingDB: Ki=7nM
    24 5etj:F (2.3) BS01 IM5 2.4.2.1 GO:0000255 ... P00491 26927977 MOAD: Kd=66pM
    BindingDB: Ki=7nM
    25 5ugf:A (2.2) BS01 IM5 2.4.2.1 GO:0000255 ... P00491 28584087 BindingDB: Ki=7nM
    26 5ugf:B (2.2) BS01 IM5 2.4.2.1 GO:0000255 ... P00491 28584087 BindingDB: Ki=7nM
    27 5ugf:C (2.2) BS01 IM5 2.4.2.1 GO:0000255 ... P00491 28584087 BindingDB: Ki=7nM
    28 5ugf:D (2.2) BS01 IM5 2.4.2.1 GO:0000255 ... P00491 28584087 BindingDB: Ki=7nM
    29 5ugf:E (2.2) BS01 IM5 2.4.2.1 GO:0000255 ... P00491 28584087 BindingDB: Ki=7nM
    30 5ugf:F (2.2) BS01 IM5 2.4.2.1 GO:0000255 ... P00491 28584087 BindingDB: Ki=7nM
    31 6aqs:A (1.57) BS01 IM5 2.4.2.1
    2.4.2.44    		 GO:0003824 ... Q8I3X4 29440412 MOAD: Ki=28nM
    PDBbind: -logKd/Ki=7.55, Ki=28nM
    32 8swr:A (2.3) BS01 IM5 2.4.2.1 GO:0003824 ... Q6CSZ6 37812583
    33 8swr:B (2.3) BS01 IM5 2.4.2.1 GO:0003824 ... Q6CSZ6 37812583
    34 8swr:D (2.3) BS01 IM5 2.4.2.1 GO:0003824 ... Q6CSZ6 37812583
    35 8sws:A (1.99) BS01 IM5 2.4.2.1 GO:0003824 ... Q6CSZ6 37812583
    36 8sws:B (1.99) BS01 IM5 2.4.2.1 GO:0003824 ... Q6CSZ6 37812583
    37 8sws:D (1.99) BS01 IM5 2.4.2.1 GO:0003824 ... Q6CSZ6 37812583
    38 8sws:E (1.99) BS01 IM5 2.4.2.1 GO:0003824 ... Q6CSZ6 37812583
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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