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BioLiP
Download all results in tab-seperated text for 28 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 2zju:A (2.58) BS01 IM4 ? GO:0004888 ... P58154 18338186 PDBbind: -logKd/Ki=5.81, Kd=1.557uM
    BindingDB: Ki=970nM
    2 2zju:A (2.58) BS02 IM4 ? GO:0004888 ... P58154 18338186 PDBbind: -logKd/Ki=5.81, Kd=1.557uM
    BindingDB: Ki=970nM
    3 2zju:B (2.58) BS01 IM4 ? GO:0004888 ... P58154 18338186 PDBbind: -logKd/Ki=5.81, Kd=1.557uM
    BindingDB: Ki=970nM
    4 2zju:B (2.58) BS02 IM4 ? GO:0004888 ... P58154 18338186 PDBbind: -logKd/Ki=5.81, Kd=1.557uM
    BindingDB: Ki=970nM
    5 2zju:C (2.58) BS01 IM4 ? GO:0004888 ... P58154 18338186 BindingDB: Ki=970nM
    6 2zju:C (2.58) BS02 IM4 ? GO:0004888 ... P58154 18338186 BindingDB: Ki=970nM
    7 2zju:D (2.58) BS01 IM4 ? GO:0004888 ... P58154 18338186 BindingDB: Ki=970nM
    8 2zju:D (2.58) BS02 IM4 ? GO:0004888 ... P58154 18338186 BindingDB: Ki=970nM
    9 2zju:E (2.58) BS01 IM4 ? GO:0004888 ... P58154 18338186 BindingDB: Ki=970nM
    10 2zju:E (2.58) BS02 IM4 ? GO:0004888 ... P58154 18338186 BindingDB: Ki=970nM
    11 3c79:A (2.48) BS01 IM4 ? GO:0004888 ... Q8WSF8 18477694 MOAD: Kd=63nM
    PDBbind: -logKd/Ki=7.20, Kd=63nM
    BindingDB: Ki=19nM
    12 3c79:A (2.48) BS02 IM4 ? GO:0004888 ... Q8WSF8 18477694 MOAD: Kd=63nM
    PDBbind: -logKd/Ki=7.20, Kd=63nM
    BindingDB: Ki=19nM
    13 3c79:B (2.48) BS01 IM4 ? GO:0004888 ... Q8WSF8 18477694 MOAD: Kd=63nM
    BindingDB: Ki=19nM
    14 3c79:B (2.48) BS02 IM4 ? GO:0004888 ... Q8WSF8 18477694 MOAD: Kd=63nM
    BindingDB: Ki=19nM
    15 3c79:C (2.48) BS01 IM4 ? GO:0004888 ... Q8WSF8 18477694 MOAD: Kd=63nM
    BindingDB: Ki=19nM
    16 3c79:C (2.48) BS02 IM4 ? GO:0004888 ... Q8WSF8 18477694 MOAD: Kd=63nM
    BindingDB: Ki=19nM
    17 3c79:D (2.48) BS01 IM4 ? GO:0004888 ... Q8WSF8 18477694 MOAD: Kd=63nM
    BindingDB: Ki=19nM
    18 3c79:E (2.48) BS01 IM4 ? GO:0004888 ... Q8WSF8 18477694 PDBbind: -logKd/Ki=7.20, Kd=63nM
    BindingDB: Ki=19nM
    19 3wth:A (2.54) BS01 IM4 ? GO:0004888 ... P58154 25267717 PDBbind: -logKd/Ki=6.29, Kd=0.514uM
    BindingDB: Ki=970nM
    20 3wth:A (2.54) BS02 IM4 ? GO:0004888 ... P58154 25267717 PDBbind: -logKd/Ki=6.29, Kd=0.514uM
    BindingDB: Ki=970nM
    21 3wth:B (2.54) BS01 IM4 ? GO:0004888 ... P58154 25267717 PDBbind: -logKd/Ki=6.29, Kd=0.514uM
    BindingDB: Ki=970nM
    22 3wth:B (2.54) BS02 IM4 ? GO:0004888 ... P58154 25267717 PDBbind: -logKd/Ki=6.29, Kd=0.514uM
    BindingDB: Ki=970nM
    23 3wth:C (2.54) BS01 IM4 ? GO:0004888 ... P58154 25267717 BindingDB: Ki=970nM
    24 3wth:C (2.54) BS02 IM4 ? GO:0004888 ... P58154 25267717 BindingDB: Ki=970nM
    25 3wth:D (2.54) BS01 IM4 ? GO:0004888 ... P58154 25267717 BindingDB: Ki=970nM
    26 3wth:D (2.54) BS02 IM4 ? GO:0004888 ... P58154 25267717 BindingDB: Ki=970nM
    27 3wth:E (2.54) BS01 IM4 ? GO:0004888 ... P58154 25267717 BindingDB: Ki=970nM
    28 3wth:E (2.54) BS02 IM4 ? GO:0004888 ... P58154 25267717 BindingDB: Ki=970nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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