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BioLiP
Download all results in tab-seperated text for 7 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 2xn3:A (2.09) BS01 ID8 ? GO:0004867 ... P05543 21325280 MOAD: Kd=89nM
    PDBbind: -logKd/Ki=5.92, Kd=1198nM
    2 2xn3:B (2.09) BS01 ID8 ? N/A P05543 21325280 PDBbind: -logKd/Ki=5.92, Kd=1198nM
    3 3r43:A (2.0) BS02 ID8 1.1.1.-
    1.1.1.188
    1.1.1.210
    1.1.1.239
    1.1.1.357
    1.1.1.53
    1.1.1.62
    1.1.1.64    		 GO:0001523 ... P42330 22937138 BindingDB: Ki=300nM, IC50=560nM
    4 4jqa:A (1.45) BS01 ID8 1.-.-.-
    1.1.1.112
    1.1.1.209
    1.1.1.357
    1.1.1.53
    1.1.1.62
    1.3.1.20    		 GO:0004032 ... P52895 N/A BindingDB: Ki=220nM, IC50=6970nM
    5 4jqa:B (1.45) BS01 ID8 1.-.-.-
    1.1.1.112
    1.1.1.209
    1.1.1.357
    1.1.1.53
    1.1.1.62
    1.3.1.20    		 GO:0004032 ... P52895 N/A BindingDB: Ki=220nM, IC50=6970nM
    6 5ikr:A (2.342) BS01 ID8 1.14.99.1 GO:0001516 ... P35354 27226593 BindingDB: Ki=2900nM, IC50=2900nM
    7 5ikr:B (2.342) BS01 ID8 1.14.99.1 GO:0001516 ... P35354 27226593 BindingDB: Ki=2900nM, IC50=2900nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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