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BioLiP
Download all results in tab-seperated text for 24 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1eqg:A (2.61) BS02 IBP 1.14.99.1 GO:0004601 ... P05979 11318639 BindingDB: IC50=2900nM, Ki=9000nM
    2 1eqg:B (2.61) BS02 IBP 1.14.99.1 GO:0004601 ... P05979 11318639 BindingDB: IC50=2900nM, Ki=9000nM
    3 2bxg:A (2.7) BS01 IBP ? GO:0003677 ... P02768 16169013 BindingDB: Ki=99999999999999nM
    4 2bxg:A (2.7) BS02 IBP ? GO:0003677 ... P02768 16169013 BindingDB: Ki=99999999999999nM
    5 2bxg:B (2.7) BS01 IBP ? GO:0003677 ... P02768 16169013 BindingDB: Ki=99999999999999nM
    6 2bxg:B (2.7) BS02 IBP ? GO:0003677 ... P02768 16169013 BindingDB: Ki=99999999999999nM
    7 2pws:A (2.21) BS01 IBP 3.1.1.4 GO:0004623 ... P59071 N/A
    8 2wd9:A (2.6) BS01 IBP 6.2.1.2
    6.2.1.25    		 GO:0004321 ... Q08AH3 19345228
    9 2wd9:B (2.6) BS02 IBP 6.2.1.2
    6.2.1.25    		 GO:0004321 ... Q08AH3 19345228
    10 2wd9:C (2.6) BS02 IBP 6.2.1.2
    6.2.1.25    		 GO:0004321 ... Q08AH3 19345228
    11 3ib2:A (2.29) BS01 IBP 3.4.21.- GO:0005576 ... P24627 20006955 MOAD: Kd=480uM
    12 3p6h:A (1.15) BS01 IBP ? GO:0005324 ... P15090 25664790
    13 4jtr:A (1.3) BS01 IBP 1.-.-.-
    1.1.1.112
    1.1.1.209
    1.1.1.357
    1.1.1.53
    1.1.1.62
    1.3.1.20    		 GO:0004032 ... P52895 N/A BindingDB: IC50=42400nM
    14 4ph9:A (1.81) BS01 IBP 1.14.99.1 GO:0001516 ... Q05769 25463020 BindingDB: IC50=860nM
    15 4ph9:B (1.81) BS01 IBP 1.14.99.1 GO:0001516 ... Q05769 25463020 BindingDB: IC50=860nM
    16 4rs0:A (2.807) BS01 IBP 1.14.99.1 GO:0001516 ... Q05769 25825493 PDBbind: -logKd/Ki=6.00, IC50=1000nM
    BindingDB: IC50=860nM
    17 5jqb:B (2.68) BS01 IBP ? N/A Q05320 27362232 PDBbind: -logKd/Ki=2.22, Kd=6mM
    18 6oci:A (2.54) BS01 IBP ? GO:0003677 ... P35747 31905261
    19 6oci:A (2.54) BS02 IBP ? GO:0003677 ... P35747 31905261
    20 6u4x:A (2.25) BS01 IBP ? GO:0003677 ... P35747 32469516
    21 6u4x:A (2.25) BS02 IBP ? GO:0003677 ... P35747 32469516
    22 7fc4:A (1.5) BS01 IBP ? GO:0005515 ... P05413 N/A
    23 8et0:A (2.15) BS01 IBP 1.14.99.1 GO:0001516 ... Q05769 N/A
    24 8et0:B (2.15) BS01 IBP 1.14.99.1 GO:0001516 ... Q05769 N/A
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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