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BioLiP
Download all results in tab-seperated text for 34 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1dwv:A (2.35) BS04 HAR 1.14.13.39 GO:0004517 ... P29477 10769116
    2 1dwv:B (2.35) BS04 HAR 1.14.13.39 GO:0004517 ... P29477 10769116
    3 1dww:A (2.35) BS04 HAR 1.14.13.39 GO:0004517 ... P29477 10769116
    4 1dww:B (2.35) BS04 HAR 1.14.13.39 GO:0004517 ... P29477 10769116
    5 1dwx:A (2.6) BS03 HAR 1.14.13.39 GO:0004517 ... P29477 10769116
    6 1dwx:B (2.6) BS03 HAR 1.14.13.39 GO:0004517 ... P29477 10769116
    7 1hqf:A (2.9) BS03 HAR 3.5.3.1 GO:0000050 ... P07824 11258880 PDBbind: -logKd/Ki=5.00, Ki=10uM
    8 1hqf:B (2.9) BS03 HAR 3.5.3.1 GO:0000050 ... P07824 11258880
    9 1hqf:C (2.9) BS03 HAR 3.5.3.1 GO:0000050 ... P07824 11258880
    10 1lzx:A (2.0) BS04 HAR 1.14.13.39 GO:0004517 ... P29476 12437343
    11 1lzx:B (2.0) BS05 HAR 1.14.13.39 GO:0004517 ... P29476 12437343
    12 1m7z:A (2.14) BS02 HAR 1.14.14.47 GO:0004517 ... O34453 12220171
    13 2fbz:X (2.1) BS03 HAR 1.14.14.47 GO:0004517 ... O34453 16489746
    14 2fc2:A (2.2) BS02 HAR 1.14.14.47 GO:0004517 ... O34453 16489746
    15 2fc2:B (2.2) BS01 HAR 1.14.14.47 GO:0004517 ... O34453 16489746
    16 3hsn:A (1.91) BS03 HAR 1.14.13.39 GO:0004517 ... P29476 19791770
    17 3hsn:B (1.91) BS05 HAR 1.14.13.39 GO:0004517 ... P29476 19791770
    18 3hso:A (2.02) BS03 HAR 1.14.13.39 GO:0004517 ... P29476 19791770
    19 3hso:B (2.02) BS03 HAR 1.14.13.39 GO:0004517 ... P29476 19791770
    20 3hsp:A (2.2) BS03 HAR 1.14.13.39 GO:0004517 ... P29476 19791770
    21 3hsp:B (2.2) BS04 HAR 1.14.13.39 GO:0004517 ... P29476 19791770
    22 3lp7:A (2.04) BS03 HAR 3.5.3.1 GO:0000050 ... P05089 20153713 MOAD: Kd=3600nM
    PDBbind: -logKd/Ki=5.44, Kd=3.6uM
    23 3lp7:B (2.04) BS03 HAR 3.5.3.1 GO:0000050 ... P05089 20153713 MOAD: Kd=3600nM
    24 3nos:A (2.4) BS02 HAR 1.14.13.39 GO:0004517 ... P29474 10074942
    25 3nos:B (2.4) BS03 HAR 1.14.13.39 GO:0004517 ... P29474 10074942
    26 4q3t:A (2.142) BS03 HAR 3.5.3.1 GO:0000050 ... Q6WVP6 25007099 MOAD: Kd=0.33uM
    PDBbind: -logKd/Ki=6.48, Kd=0.33uM
    27 4q3t:B (2.142) BS03 HAR 3.5.3.1 GO:0000050 ... Q6WVP6 25007099 MOAD: Kd=0.33uM
    28 4q3t:C (2.142) BS03 HAR 3.5.3.1 GO:0000050 ... Q6WVP6 25007099 MOAD: Kd=0.33uM
    29 4q3t:D (2.142) BS01 HAR 3.5.3.1 GO:0000050 ... Q6WVP6 25007099 MOAD: Kd=0.33uM
    30 5nse:A (1.9) BS03 HAR 1.14.13.39 GO:0004517 ... P29473 N/A
    31 5nse:B (1.9) BS03 HAR 1.14.13.39 GO:0004517 ... P29473 N/A
    32 5vka:A (1.169) BS03 HAR 1.13.12.19
    1.14.20.7    		 GO:0009693 ... P32021 28780854
    33 5zee:A (1.74) BS01 HAR 3.5.3.1 GO:0000050 ... C4LSS0 31199070 PDBbind: -logKd/Ki=2.80, IC50=1.57mM
    34 5zee:B (1.74) BS01 HAR 3.5.3.1 GO:0000050 ... C4LSS0 31199070
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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