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BioLiP
Download all results in tab-seperated text for 11 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1dx6:A (2.3) BS01 GNT 3.1.1.7 GO:0001507 ... P04058 10606746 MOAD: ic50=652nM
    PDBbind: -logKd/Ki=6.19, IC50=652nM
    BindingDB: IC50=1069nM, Ki=1.9e+2nM
    2 1qti:A (2.5) BS01 GNT 3.1.1.7 GO:0001507 ... P04058 11119642 PDBbind: -logKd/Ki=6.44, IC50=0.36uM
    BindingDB: IC50=1069nM, Ki=1.9e+2nM
    3 1w6r:A (2.05) BS01 GNT 3.1.1.7 GO:0001507 ... P04058 15563167 MOAD: ic50=702nM
    PDBbind: -logKd/Ki=6.15, IC50=702nM
    BindingDB: IC50=1069nM, Ki=1.9e+2nM
    4 1w76:A (2.3) BS01 GNT 3.1.1.7 GO:0001507 ... P04058 15563167 MOAD: ic50=702nM
    PDBbind: -logKd/Ki=6.15, IC50=702nM
    BindingDB: IC50=1069nM, Ki=1.9e+2nM
    5 1w76:B (2.3) BS01 GNT 3.1.1.7 GO:0001507 ... P04058 15563167 MOAD: ic50=702nM
    BindingDB: IC50=1069nM, Ki=1.9e+2nM
    6 2ph9:A (2.88) BS01 GNT ? GO:0004888 ... Q8WSF8 17481657 PDBbind: -logKd/Ki=5.89, Kd=1.3uM
    7 2ph9:C (2.88) BS01 GNT ? GO:0004888 ... Q8WSF8 17481657
    8 2ph9:D (2.88) BS01 GNT ? GO:0004888 ... Q8WSF8 17481657
    9 2ph9:E (2.88) BS01 GNT ? GO:0004888 ... Q8WSF8 17481657
    10 4ey6:A (2.3983) BS01 GNT 3.1.1.7 GO:0001507 ... P22303 23035744 BindingDB: IC50=800nM, Ki=62nM, EC50=1100nM
    11 4ey6:B (2.3983) BS01 GNT 3.1.1.7 GO:0001507 ... P22303 23035744 BindingDB: IC50=800nM, Ki=62nM, EC50=1100nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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