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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
Download all results in tab-seperated text for 6479 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    401 2gj9:B (2.0) BS03 GDP 3.6.-.- GO:0005525 ... P25522 16763562
    402 2gj9:C (2.0) BS03 GDP 3.6.-.- GO:0005525 ... P25522 16763562
    403 2gj9:D (2.0) BS03 GDP 3.6.-.- GO:0005525 ... P25522 16763562
    404 2gja:A (1.85) BS03 GDP 3.6.-.- GO:0005525 ... P25522 16763562
    405 2gja:B (1.85) BS03 GDP 3.6.-.- GO:0005525 ... P25522 16763562
    406 2gjs:A (1.9) BS01 GDP ? GO:0003924 ... P55042 N/A
    407 2gjs:B (1.9) BS01 GDP ? GO:0003924 ... P55042 N/A
    408 2gtp:A (2.55) BS03 GDP ? GO:0000287 ... P63096 18434541
    409 2gtp:B (2.55) BS03 GDP ? GO:0000287 ... P63096 18434541
    410 2h16:A (2.0) BS01 GDP ? GO:0003924 ... Q9Y689 N/A
    411 2h16:B (2.0) BS01 GDP ? GO:0003924 ... Q9Y689 N/A
    412 2h16:C (2.0) BS01 GDP ? GO:0003924 ... Q9Y689 N/A
    413 2h16:D (2.0) BS01 GDP ? GO:0003924 ... Q9Y689 N/A
    414 2h17:A (1.7) BS01 GDP ? GO:0003924 ... Q9Y689 N/A
    415 2h18:A (1.902) BS01 GDP ? GO:0003924 ... Q96BM9 N/A
    416 2h5e:A (2.8) BS01 GDP ? GO:0003924 ... P0A7I4 17540173 PDBbind: -logKd/Ki=8.25, Kd=5.6nM
    417 2h5e:B (2.8) BS01 GDP ? GO:0003924 ... P0A7I4 17540173
    418 2h7v:A (2.6) BS02 GDP 3.6.5.2 GO:0001764 ... P63000 16959567
    419 2h7v:B (2.6) BS02 GDP 3.6.5.2 GO:0001764 ... P63000 16959567
    420 2hcj:A (2.12) BS01 GDP ? GO:0003924 ... P0CE47 17057344
    421 2hcj:B (2.12) BS01 GDP ? GO:0003746 ... P0CE47 17057344
    422 2hdn:A (2.8) BS01 GDP ? GO:0003924 ... P0CE47 17057344
    423 2hdn:B (2.8) BS01 GDP ? GO:0003746 ... P0CE47 17057344
    424 2hdn:C (2.8) BS01 GDP ? GO:0003924 ... P0CE47 17057344
    425 2hdn:D (2.8) BS01 GDP ? GO:0003746 ... P0CE47 17057344
    426 2hdn:E (2.8) BS01 GDP ? GO:0003924 ... P0CE47 17057344
    427 2hdn:F (2.8) BS01 GDP ? GO:0003746 ... P0CE47 17057344
    428 2hdn:G (2.8) BS01 GDP ? GO:0003924 ... P0CE47 17057344
    429 2hdn:H (2.8) BS01 GDP ? GO:0003746 ... P0CE47 17057344
    430 2hdn:I (2.8) BS01 GDP ? GO:0003924 ... P0CE47 17057344
    431 2hdn:J (2.8) BS01 GDP ? GO:0003746 ... P0CE47 17057344
    432 2hdn:K (2.8) BS01 GDP ? GO:0003924 ... P0CE47 17057344
    433 2hdn:L (2.8) BS01 GDP ? GO:0003746 ... P0CE47 17057344
    434 2hei:A (1.55) BS01 GDP 3.6.5.2 GO:0003924 ... P61020 N/A
    435 2hei:B (1.55) BS01 GDP 3.6.5.2 GO:0003924 ... P61020 N/A
    436 2hek:A (1.997) BS02 GDP ? GO:0006203 ... O67745 17565173
    437 2hek:A (1.997) BS03 GDP ? GO:0006203 ... O67745 17565173
    438 2hek:B (1.997) BS01 GDP ? GO:0006203 ... O67745 17565173
    439 2hek:B (1.997) BS02 GDP ? GO:0006203 ... O67745 17565173
    440 2hjg:A (2.5) BS02 GDP ? GO:0005525 ... P50743 16894162
    441 2hjg:A (2.5) BS03 GDP ? GO:0005525 ... P50743 16894162
    442 2ht6:A (2.4) BS01 GDP ? GO:0003924 ... P55040 17052716
    443 2ht6:B (2.4) BS01 GDP ? GO:0003924 ... P55040 17052716
    444 2hup:A (2.05) BS01 GDP ? GO:0003924 ... Q86YS6 N/A
    445 2hup:B (2.05) BS01 GDP ? GO:0003924 ... Q86YS6 N/A
    446 2hxf:B (10.0) BS01 GDP ? GO:0000226 ... P02554 16946706
    447 2hxh:B (11.0) BS01 GDP ? GO:0000226 ... P02554 16946706
    448 2i8u:A (1.4) BS02 GDP 3.6.1.- GO:0000287 ... Q6XQ58 17371001
    449 2i8u:B (1.4) BS02 GDP 3.6.1.- GO:0000287 ... Q6XQ58 17371001
    450 2ic5:B (1.9) BS01 GDP 3.6.5.2 GO:0003924 ... P60763 N/A
    451 2iey:A (3.18) BS01 GDP 3.6.5.2 GO:0003924 ... Q99P58 17582168
    452 2iey:B (3.18) BS01 GDP 3.6.5.2 GO:0003924 ... Q99P58 17582168
    453 2iez:A (2.8) BS01 GDP 3.6.5.2 GO:0003924 ... Q99P58 17582168
    454 2iez:B (2.8) BS01 GDP 3.6.5.2 GO:0003924 ... Q99P58 17582168
    455 2iez:H (2.8) BS01 GDP 3.6.5.2 GO:0003924 ... Q99P58 17582168
    456 2iez:I (2.8) BS01 GDP 3.6.5.2 GO:0003924 ... Q99P58 17582168
    457 2if0:A (2.8) BS01 GDP 3.6.5.2 GO:0003924 ... Q99P58 17582168
    458 2if0:B (2.8) BS01 GDP 3.6.5.2 GO:0003924 ... Q99P58 17582168
    459 2ihb:A (2.71) BS03 GDP ? GO:0000139 ... P08754 18434541
    460 2ik8:A (2.71) BS03 GDP ? GO:0000287 ... P63096 18434541
    461 2ik8:C (2.71) BS03 GDP ? GO:0000287 ... P63096 18434541
    462 2il1:A (2.1) BS02 GDP ? GO:0003924 ... Q6IQ22 N/A
    463 2iyl:D (2.1) BS01 GDP 3.6.5.4 GO:0003924 ... P83749 17186523
    464 2j0v:A (1.78) BS01 GDP ? GO:0003924 ... O82480 17005216
    465 2j0v:A (1.78) BS03 GDP ? GO:0003924 ... O82480 17005216
    466 2j0v:B (1.78) BS01 GDP ? GO:0003924 ... O82480 17005216
    467 2j0v:B (1.78) BS02 GDP ? GO:0003924 ... O82480 17005216
    468 2j0v:C (1.78) BS01 GDP ? GO:0003924 ... O82480 17005216
    469 2j0v:C (1.78) BS03 GDP ? GO:0003924 ... O82480 17005216
    470 2j0v:D (1.78) BS01 GDP ? GO:0003924 ... O82480 17005216
    471 2j0v:D (1.78) BS02 GDP ? GO:0003924 ... O82480 17005216
    472 2j1l:A (2.5) BS01 GDP 3.6.5.2 GO:0000139 ... O00212 N/A
    473 2j3e:A (3.2) BS01 GDP 3.6.5.- GO:0005525 ... O23680 17337454
    474 2j68:A (3.1) BS01 GDP 3.6.5.5 GO:0003924 ... B2IZD3 17122778
    475 2k5u:A (-1.00) BS01 GDP 3.6.5.2 GO:0003924 ... P11076 19141284
    476 2l0x:A (-1.00) BS02 GDP 3.6.5.- GO:0000139 ... Q62639 20685651
    477 2lkd:A (-1.00) BS01 GDP ? GO:0003924 ... P04766 22308033
    478 2msc:B (-1.00) BS04 GDP 3.6.5.2 GO:0000139 ... P01116 25941399
    479 2ng1:A (2.02) BS01 GDP 3.6.5.4 GO:0003924 ... O07347 10426959
    480 2ngr:A (1.9) BS02 GDP 3.6.5.2 GO:0000139 ... P60953 9846874
    481 2npf:A (2.9) BS02 GDP 3.6.5.- GO:0003746 ... P32324 17082187
    482 2npf:B (2.9) BS02 GDP 3.6.5.- GO:0003746 ... P32324 17082187
    483 2nty:C (3.1) BS01 GDP ? GO:0003924 ... Q38937 17218277
    484 2nty:D (3.1) BS01 GDP ? GO:0003924 ... Q38937 17218277
    485 2nzj:A (2.5) BS01 GDP ? GO:0003924 ... O75628 N/A
    486 2nzj:B (2.5) BS01 GDP ? GO:0003924 ... O75628 N/A
    487 2nzj:C (2.5) BS01 GDP ? GO:0003924 ... O75628 N/A
    488 2nzj:D (2.5) BS01 GDP ? GO:0003924 ... O75628 N/A
    489 2nzx:A (1.9) BS01 GDP 2.4.1.152 GO:0006486 ... O30511 17251184
    490 2nzx:B (1.9) BS01 GDP 2.4.1.152 GO:0006486 ... O30511 17251184
    491 2nzx:C (1.9) BS01 GDP 2.4.1.152 GO:0006486 ... O30511 17251184
    492 2nzy:A (2.05) BS02 GDP 2.4.1.152 GO:0006486 ... O30511 17251184
    493 2nzy:B (2.05) BS02 GDP 2.4.1.152 GO:0006486 ... O30511 17251184
    494 2nzy:C (2.05) BS02 GDP 2.4.1.152 GO:0006486 ... O30511 17251184
    495 2o52:A (2.2) BS01 GDP 3.6.5.2 GO:0003924 ... P61018 N/A
    496 2o52:B (2.2) BS01 GDP 3.6.5.2 GO:0003924 ... P61018 N/A
    497 2ode:A (1.9) BS03 GDP ? GO:0000139 ... P08754 18434541
    498 2ode:C (1.9) BS03 GDP ? GO:0000139 ... P08754 18434541
    499 2ogi:A (1.85) BS03 GDP 3.6.1.41 GO:0000166 ... Q8DY32 N/A
    500 2ogi:B (1.85) BS03 GDP 3.6.1.41 GO:0000166 ... Q8DY32 N/A
    501 2oil:A (2.3) BS01 GDP ? GO:0003924 ... P57735 N/A
    502 2om2:A (2.2) BS01 GDP ? GO:0000287 ... P63096 17603074
    503 2om2:C (2.2) BS02 GDP ? GO:0000287 ... P63096 17603074
    504 2oxr:A (2.4) BS01 GDP 3.6.5.- GO:0003924 ... Q9UYR9 17468740
    505 2p2l:A (1.9) BS04 GDP 3.6.5.2 GO:0001764 ... P63000 17452788
    506 2p2l:B (1.9) BS03 GDP 3.6.5.2 GO:0001764 ... P63000 17452788
    507 2p2l:C (1.9) BS03 GDP 3.6.5.2 GO:0001764 ... P63000 17452788
    508 2p4n:B (9.0) BS01 GDP ? GO:0000226 ... Q6B856 17470637
    509 2p5s:A (2.15) BS01 GDP ? GO:0003924 ... Q8IZ41 N/A
    510 2p5s:B (2.15) BS01 GDP ? GO:0003924 ... Q8IZ41 N/A
    511 2p8y:T (11.7) BS03 GDP 3.6.5.- GO:0003746 ... P32324 17446867
    512 2phn:A (1.35) BS03 GDP 6.3.2.31
    6.3.2.34
    GO:0005525 ... O28028 17669425
    513 2phn:B (1.35) BS03 GDP 6.3.2.31
    6.3.2.34
    GO:0005525 ... O28028 17669425
    514 2pmd:A (2.65) BS01 GDP 3.6.5.3 GO:0000049 ... Q980A5 17825838
    515 2pmd:B (2.65) BS01 GDP 3.6.5.3 GO:0000049 ... Q980A5 17825838
    516 2q21:A (2.2) BS01 GDP 3.6.5.2 GO:0000139 ... P01112 1899707
    517 2q3h:A (1.73) BS01 GDP ? GO:0003924 ... Q7L0Q8 N/A
    518 2qa5:A (3.4) BS01 GDP ? GO:0005525 ... Q15019 17637674
    519 2qa5:B (3.4) BS01 GDP ? GO:0005525 ... Q15019 17637674
    520 2qag:A (4.0) BS01 GDP ? GO:0000775 ... Q15019 17637674
    521 2qag:B (4.0) BS01 GDP ? GO:0000281 ... Q14141 17637674
    522 2qag:C (4.0) BS01 GDP ? GO:0000775 ... Q16181 17637674
    523 2qf2:A (1.65) BS05 GDP 2.7.11.-
    4.1.1.32
    GO:0000287 ... P07379 17685635
    524 2qf2:A (1.65) BS06 GDP 2.7.11.-
    4.1.1.32
    GO:0000287 ... P07379 17685635
    525 2qf2:B (1.65) BS04 GDP 2.7.11.-
    4.1.1.32
    GO:0000287 ... P07379 17685635
    526 2qm7:A (1.85) BS01 GDP ? GO:0003924 ... Q8RPA0 17728257 PDBbind: -logKd/Ki=5.89, Kd=1.3uM
    527 2qm7:B (1.85) BS01 GDP ? GO:0003924 ... Q8RPA0 17728257
    528 2qmu:A (3.2) BS01 GDP 3.6.5.3 GO:0000049 ... Q980A5 18000047
    529 2qn6:A (2.15) BS02 GDP 3.6.5.3 GO:0000049 ... Q980A5 18000047
    530 2qnr:A (2.6) BS01 GDP ? GO:0005525 ... Q15019 N/A
    531 2qnr:B (2.6) BS01 GDP ? GO:0005525 ... Q15019 N/A
    532 2qth:A (2.0) BS01 GDP ? GO:0003924 ... Q980M3 N/A
    533 2qu8:A (2.01) BS01 GDP N/A GO:0005525 ... N/A N/A
    534 2quz:A (1.49) BS01 GDP 3.6.5.2 GO:0003924 ... P01112 17979197
    535 2r6r:1 (1.7) BS01 GDP ? GO:0000917 ... O66809 17900614
    536 2rcn:A (2.25) BS02 GDP 3.6.1.- GO:0003924 ... Q8ZKB0 18007041 MOAD: Kd=1uM
    PDBbind: -logKd/Ki=6.00, Kd=1.0uM
    537 2rgn:A (3.5) BS03 GDP ? GO:0001501 ... P10824
    P21279
    18096806
    538 2rgn:D (3.5) BS03 GDP ? GO:0001501 ... P10824
    P21279
    18096806
    539 2rhd:A (2.06) BS01 GDP N/A GO:0003924 ... N/A N/A
    540 2rhl:A (2.45) BS01 GDP ? GO:0003924 ... P17865 19383143
    541 2rhl:B (2.45) BS01 GDP ? GO:0003924 ... P17865 19383143
    542 2rho:B (2.45) BS01 GDP ? GO:0003924 ... P17865 19383143
    543 2rok:A (-1.00) BS02 GDP 3.1.13.4 GO:0003676 ... Q8VDG3 18641416 PDBbind: -logKd/Ki=4.35, Kd=45uM
    544 2v40:A (1.9) BS01 GDP 6.3.4.4 GO:0000166 ... P30520 N/A
    545 2v4z:A (2.8) BS01 GDP ? GO:0000139 ... P08754 19478087
    546 2vap:A (1.7) BS01 GDP ? GO:0000917 ... Q57816 17900614
    547 2vaw:A (2.9) BS01 GDP ? GO:0000917 ... P47204 17900614
    548 2w2t:A (1.95) BS01 GDP ? GO:0003924 ... P15153 19394299
    549 2w6d:A (9.0) BS01 GDP 3.6.5.5 GO:0003924 ... B2IZD3 20064379
    550 2w6d:A (9.0) BS12 GDP 3.6.5.5 GO:0003924 ... B2IZD3 20064379
    551 2w6d:B (9.0) BS01 GDP 3.6.5.5 GO:0003924 ... B2IZD3 20064379
    552 2w6d:B (9.0) BS12 GDP 3.6.5.5 GO:0003924 ... B2IZD3 20064379
    553 2wbe:B (9.4) BS02 GDP ? GO:0000226 ... Q6B856 19285086
    554 2wib:A (2.56) BS01 GDP ? GO:0005525 ... A6TF32 20123128 PDBbind: -logKd/Ki=4.93, Kd=11.8uM
    555 2wib:A (2.56) BS02 GDP ? GO:0005525 ... A6TF32 20123128 PDBbind: -logKd/Ki=4.93, Kd=11.8uM
    556 2wib:B (2.56) BS01 GDP ? GO:0005525 ... A6TF32 20123128
    557 2wib:B (2.56) BS02 GDP ? GO:0005525 ... A6TF32 20123128
    558 2wjg:A (2.2) BS01 GDP ? GO:0005525 ... Q57986 19615379 PDBbind: -logKd/Ki=7.10, Kd=0.08uM
    559 2wjg:B (2.2) BS01 GDP ? GO:0005525 ... Q57986 19615379
    560 2wjh:A (2.1) BS01 GDP ? GO:0005525 ... Q57986 19615379
    561 2wjj:A (2.405) BS01 GDP ? GO:0005525 ... Q57986 19615379
    562 2wjj:B (2.405) BS01 GDP ? GO:0005525 ... Q57986 19615379
    563 2wmn:B (2.391) BS01 GDP 3.6.5.2 GO:0000139 ... P60953 19745154
    564 2www:A (2.64) BS01 GDP 3.6.-.- GO:0003924 ... Q8IVH4 20876572
    565 2www:B (2.64) BS01 GDP 3.6.-.- GO:0003924 ... Q8IVH4 20876572
    566 2www:C (2.64) BS01 GDP 3.6.-.- GO:0003924 ... Q8IVH4 20876572
    567 2www:D (2.64) BS01 GDP 3.6.-.- GO:0003924 ... Q8IVH4 20876572
    568 2x1v:A (1.7) BS01 GDP 3.6.5.2 GO:0003924 ... P01112 N/A
    569 2x2e:A (2.0) BS01 GDP 3.6.5.5 GO:0003924 ... Q05193 20428113
    570 2x2e:D (2.0) BS01 GDP 3.6.5.5 GO:0003924 ... Q05193 20428113
    571 2x2f:A (2.0) BS01 GDP 3.6.5.5 GO:0003924 ... Q05193 20428113
    572 2x2f:D (2.0) BS01 GDP 3.6.5.5 GO:0003924 ... Q05193 20428113
    573 2x77:A (2.1) BS01 GDP ? GO:0003924 ... Q4QEJ1 20801163
    574 2x77:B (2.1) BS01 GDP ? GO:0003924 ... Q4QEJ1 20801163
    575 2xkb:A (3.0) BS01 GDP 3.6.5.- N/A Q8KNP3 20974911
    576 2xkb:B (3.0) BS01 GDP 3.6.5.- N/A Q8KNP3 20974911
    577 2xkb:C (3.0) BS01 GDP 3.6.5.- N/A Q8KNP3 20974911
    578 2xkb:D (3.0) BS01 GDP 3.6.5.- N/A Q8KNP3 20974911
    579 2xkb:E (3.0) BS01 GDP 3.6.5.- N/A Q8KNP3 20974911
    580 2xkb:F (3.0) BS01 GDP 3.6.5.- N/A Q8KNP3 20974911
    581 2xkb:G (3.0) BS01 GDP 3.6.5.- N/A Q8KNP3 20974911
    582 2xkb:I (3.0) BS01 GDP 3.6.5.- N/A Q8KNP3 20974911
    583 2xkb:J (3.0) BS01 GDP 3.6.5.- N/A Q8KNP3 20974911
    584 2xkb:K (3.0) BS01 GDP 3.6.5.- N/A Q8KNP3 20974911
    585 2xkb:L (3.0) BS01 GDP 3.6.5.- N/A Q8KNP3 20974911
    586 2xns:A (3.41) BS01 GDP 3.6.5.1 GO:0000287 ... P63096 21388199
    587 2xns:B (3.41) BS01 GDP 3.6.5.1 GO:0000287 ... P63096 21388199
    588 2xrp:A (8.2) BS01 GDP 3.6.5.6 GO:0000226 ... Q6B856 20974813
    589 2xrp:C (8.2) BS01 GDP 3.6.5.6 GO:0000226 ... Q6B856 20974813
    590 2xrp:E (8.2) BS01 GDP 3.6.5.6 GO:0000226 ... Q6B856 20974813
    591 2xrp:G (8.2) BS01 GDP 3.6.5.6 GO:0000226 ... Q6B856 20974813
    592 2xtm:A (1.7) BS01 GDP ? GO:0005525 ... Q9UG22 21059949 MOAD: Kd=630nM
    593 2xtm:B (1.7) BS01 GDP ? GO:0005525 ... Q9UG22 21059949 MOAD: Kd=630nM
    594 2xto:A (2.8) BS01 GDP ? GO:0005525 ... Q9UG22 21059949 PDBbind: -logKd/Ki=6.20, Kd=630nM
    595 2xto:B (2.8) BS01 GDP ? GO:0005525 ... Q9UG22 21059949
    596 2y4k:A (2.45) BS01 GDP 2.4.1.217 GO:0046872 ... D0MI02 21288903 PDBbind: -logKd/Ki=5.46, Kd=3.5uM
    597 2y4k:B (2.45) BS01 GDP 2.4.1.217 GO:0046872 ... D0MI02 21288903
    598 2y4l:A (2.8) BS02 GDP 2.4.1.217 GO:0046872 ... D0MI02 21288903 PDBbind: -logKd/Ki=6.30, Kd=0.5uM
    599 2y4l:B (2.8) BS01 GDP 2.4.1.217 GO:0046872 ... D0MI02 21288903
    600 2ydc:A (2.05) BS01 GDP 3.1.4.37 GO:0004113 ... P16330 N/A

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218