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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
Download all results in tab-seperated text for 6479 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    201 1t2a:A (1.84) BS02 GDP 4.2.1.47 GO:0005515 ... O60547 N/A
    202 1t2a:B (1.84) BS02 GDP 4.2.1.47 GO:0005515 ... O60547 N/A
    203 1t2a:C (1.84) BS03 GDP 4.2.1.47 GO:0005515 ... O60547 N/A
    204 1t2a:D (1.84) BS03 GDP 4.2.1.47 GO:0005515 ... O60547 N/A
    205 1tad:A (1.7) BS03 GDP ? GO:0000035 ... P04695 7969474
    206 1tad:B (1.7) BS03 GDP ? GO:0000035 ... P04695 7969474
    207 1tad:C (1.7) BS03 GDP ? GO:0000035 ... P04695 7969474
    208 1tag:A (1.8) BS01 GDP ? GO:0000035 ... P04695 8208289
    209 1tpz:A (2.0) BS01 GDP 3.6.5.- GO:0003924 ... Q9QZ85 15350217 MOAD: Kd=0.64uM
    PDBbind: -logKd/Ki=6.19, Kd=0.64uM
    210 1tpz:B (2.0) BS01 GDP 3.6.5.- GO:0003924 ... Q9QZ85 15350217 MOAD: Kd=0.64uM
    211 1tq4:A (1.95) BS01 GDP 3.6.5.- GO:0003924 ... Q9QZ85 15350217 MOAD: Kd=0.64uM
    PDBbind: -logKd/Ki=6.19, Kd=0.64uM
    212 1tu4:A (2.2) BS01 GDP 3.6.5.2 GO:0003924 ... P20339 15378032
    213 1tu4:B (2.2) BS02 GDP 3.6.5.2 GO:0003924 ... P20339 15378032
    214 1tu4:C (2.2) BS01 GDP 3.6.5.2 GO:0003924 ... P20339 15378032
    215 1tu4:D (2.2) BS02 GDP 3.6.5.2 GO:0003924 ... P20339 15378032
    216 1tub:B (3.7) BS02 GDP ? GO:0000226 ... P02554 9428769
    217 1tui:A (2.7) BS02 GDP ? GO:0003746 ... Q01698 8939739
    218 1tui:B (2.7) BS01 GDP ? GO:0003746 ... Q01698 8939739
    219 1tui:C (2.7) BS01 GDP ? GO:0003746 ... Q01698 8939739
    220 1tvk:B (2.89) BS01 GDP ? GO:0000226 ... Q6B856 15297674
    221 1tx4:B (1.65) BS03 GDP 3.6.5.2 GO:0000902 ... P61586 9338791
    222 1u0l:A (2.8) BS02 GDP 3.6.1.- GO:0003924 ... Q9X242 15331784
    223 1u0l:B (2.8) BS02 GDP 3.6.1.- GO:0003924 ... Q9X242 15331784
    224 1u0l:C (2.8) BS02 GDP 3.6.1.- GO:0003924 ... Q9X242 15331784
    225 1u2r:A (2.6) BS03 GDP 3.6.5.- GO:0003746 ... P32324 15316019 PDBbind: -logKd/Ki=5.41, Kd=3.9uM
    226 1u81:A (-1.00) BS01 GDP 3.6.5.2 GO:0000139 ... P84077 15308674
    227 1u8z:A (1.5) BS01 GDP 3.6.5.2 GO:0003924 ... P63320 15530367
    228 1u8z:B (1.5) BS01 GDP 3.6.5.2 GO:0003924 ... P63320 15530367
    229 1u90:A (2.0) BS01 GDP 3.6.5.2 GO:0003924 ... P63320 15530367
    230 1u90:B (2.0) BS01 GDP 3.6.5.2 GO:0003924 ... P63320 15530367
    231 1ukv:Y (1.5) BS01 GDP ? GO:0000045 ... P01123 14576435
    232 1vg0:B (2.2) BS01 GDP 3.6.5.2 GO:0000045 ... P09527 15186776
    233 1vg1:A (1.9) BS01 GDP 3.6.5.2 GO:0003924 ... P09527 15186776
    234 1vg9:B (2.5) BS01 GDP 3.6.5.2 GO:0003924 ... P09527 15186776
    235 1vg9:D (2.5) BS01 GDP 3.6.5.2 GO:0003924 ... P09527 15186776
    236 1vg9:F (2.5) BS01 GDP 3.6.5.2 GO:0003924 ... P09527 15186776
    237 1vg9:H (2.5) BS01 GDP 3.6.5.2 GO:0003924 ... P09527 15186776
    238 1vj7:A (2.1) BS02 GDP 2.7.6.5
    3.1.7.2
    GO:0015969 ... Q54089 15066282
    239 1vj7:B (2.1) BS02 GDP 2.7.6.5
    3.1.7.2
    GO:0015969 ... Q54089 15066282
    240 1wkk:A (2.7) BS01 GDP 2.7.4.6 GO:0004550 ... Q5SLV5 N/A
    241 1wms:A (1.25) BS01 GDP ? GO:0003924 ... P51151 15263003
    242 1wms:B (1.25) BS01 GDP ? GO:0003924 ... P51151 15263003
    243 1wq1:G (2.5) BS01 GDP ? GO:0043087 ... P20936 9219684
    244 1wq1:R (2.5) BS02 GDP 3.6.5.2 GO:0003924 ... P01112 9219684
    245 1x1r:A (1.3) BS01 GDP 3.6.5.2 GO:0003924 ... O08989 15994326
    246 1xd2:A (2.7) BS02 GDP 3.6.5.2 GO:0003924 ... P01112 15507210
    247 1xj0:A (1.7) BS01 GDP 3.6.5.2 GO:0003924 ... P01112 N/A
    248 1xje:A (1.9) BS01 GDP 1.17.4.1 GO:0000166 ... O33839 15475969
    249 1xje:B (1.9) BS02 GDP 1.17.4.1 GO:0000166 ... O33839 15475969
    250 1xtq:A (2.0) BS01 GDP 3.6.5.- GO:0000139 ... Q15382 15728574
    251 1y3a:A (2.5) BS02 GDP ? GO:0000287 ... P63096 16004878
    252 1y3a:B (2.5) BS02 GDP ? GO:0000287 ... P63096 16004878
    253 1y3a:C (2.5) BS02 GDP ? GO:0000287 ... P63096 16004878
    254 1y3a:D (2.5) BS03 GDP ? GO:0000287 ... P63096 16004878
    255 1yr9:A (2.8) BS01 GDP 3.6.5.- GO:0003924 ... Q9UYR9 17468740
    256 1yra:A (2.3) BS01 GDP 3.6.5.- GO:0003924 ... Q9UYR9 17468740
    257 1yra:B (2.3) BS01 GDP 3.6.5.- GO:0003924 ... Q9UYR9 17468740
    258 1yrb:A (1.75) BS01 GDP 3.6.5.- GO:0003924 ... Q9UYR9 17468740
    259 1yrb:B (1.75) BS02 GDP 3.6.5.- GO:0003924 ... Q9UYR9 17468740
    260 1yzg:A (2.0) BS01 GDP ? GO:0003924 ... Q96KC2 N/A
    261 1z0a:A (2.12) BS02 GDP 3.6.5.2 GO:0003924 ... P61019 16034420
    262 1z0a:B (2.12) BS01 GDP 3.6.5.2 GO:0003924 ... P61019 16034420
    263 1z0a:C (2.12) BS01 GDP 3.6.5.2 GO:0003924 ... P61019 16034420
    264 1z0a:D (2.12) BS01 GDP 3.6.5.2 GO:0003924 ... P61019 16034420
    265 1z0d:A (2.2) BS01 GDP 3.6.5.2 GO:0003924 ... P35278 16034420
    266 1z0d:C (2.2) BS01 GDP 3.6.5.2 GO:0003924 ... P35278 16034420
    267 1z0f:A (2.15) BS02 GDP 3.6.5.2 GO:0003924 ... P61106 16034420
    268 1z0i:A (2.33) BS01 GDP ? GO:0003924 ... Q9UL25 16034420
    269 1z22:A (2.06) BS01 GDP ? GO:0003924 ... P35288 16034420
    270 1z2a:A (1.9) BS01 GDP ? GO:0003924 ... P35288 16034420
    271 1z2b:B (4.1) BS01 GDP ? GO:0000226 ... Q6B856 15917812
    272 1z2b:D (4.1) BS01 GDP ? GO:0000226 ... Q6B856 15917812
    273 1z6x:A (2.7) BS01 GDP ? GO:0000139 ... P18085 N/A
    274 1z6x:B (2.7) BS02 GDP ? GO:0000139 ... P18085 N/A
    275 1z6y:A (2.4) BS01 GDP ? GO:0003924 ... Q9Y689 N/A
    276 1z6y:B (2.4) BS01 GDP ? GO:0003924 ... Q9Y689 N/A
    277 1zca:A (2.9) BS03 GDP ? GO:0001664 ... P27600 16388592
    278 1zca:B (2.9) BS03 GDP ? GO:0001664 ... P27600 16388592
    279 1zcb:A (2.0) BS01 GDP ? GO:0001525 ... P27601 16388592
    280 1zd9:A (1.7) BS01 GDP ? GO:0003924 ... Q96BM9 N/A
    281 1zny:A (2.3) BS01 GDP 2.7.4.8 GO:0000287 ... P9WKE9 16288457
    282 1znz:A (2.5) BS01 GDP 2.7.4.8 GO:0000287 ... P9WKE9 16288457
    283 1zun:B (2.7) BS01 GDP 2.7.1.25
    2.7.7.4
    GO:0003924 ... Q87WW1 16387658
    284 1zvq:A (2.0) BS01 GDP 3.6.5.2 GO:0003924 ... P01112 16531227
    285 2a5j:A (1.501) BS01 GDP 3.6.5.2 GO:0003924 ... Q8WUD1 N/A
    286 2a78:A (1.81) BS01 GDP 3.6.5.2 GO:0003924 ... P11233 16177825
    287 2a9k:A (1.73) BS01 GDP 3.6.5.2 GO:0003924 ... P11233 16177825
    288 2al7:A (1.85) BS01 GDP 3.6.5.2 GO:0001778 ... Q9NVJ2 N/A
    289 2an9:A (2.35) BS01 GDP 2.7.4.8 GO:0004385 ... P60546 16140325
    290 2an9:B (2.35) BS01 GDP 2.7.4.8 GO:0004385 ... P60546 16140325
    291 2atq:A (3.2) BS01 GDP 2.7.7.7
    3.1.11.-
    GO:0000166 ... Q38087 16881051
    292 2atv:A (1.9) BS01 GDP 3.6.5.2 GO:0003924 ... Q96A58 N/A
    293 2b6h:A (1.764) BS01 GDP ? GO:0003924 ... P84085 N/A
    294 2b7b:A (2.6) BS01 GDP ? GO:0000329 ... P02994 16675455
    295 2b92:A (3.2) BS02 GDP 3.6.1.-
    3.6.5.-
    GO:0003924 ... P32455 16511497
    296 2b92:B (3.2) BS02 GDP 3.6.1.-
    3.6.5.-
    GO:0003924 ... P32455 16511497
    297 2bcg:Y (1.48) BS01 GDP ? GO:0000045 ... P01123 16395334
    298 2bcj:Q (3.061) BS03 GDP ? GO:0001501 ... P10824
    P21279
    16339447
    299 2bm0:A (2.4) BS01 GDP ? GO:0000287 ... P13551 15843024 MOAD: Ki=440uM
    300 2bm1:A (2.6) BS01 GDP ? GO:0000287 ... P13551 15843024
    301 2bmd:A (1.8) BS01 GDP 3.6.5.2 GO:0003924 ... P20338 15907487
    302 2bo7:A (2.95) BS01 GDP 2.4.1.269 GO:0016740 ... Q9RFR0 15951819
    303 2bo7:B (2.95) BS01 GDP 2.4.1.269 GO:0016740 ... Q9RFR0 15951819
    304 2bo7:C (2.95) BS01 GDP 2.4.1.269 GO:0016740 ... Q9RFR0 15951819
    305 2bo7:D (2.95) BS01 GDP 2.4.1.269 GO:0016740 ... Q9RFR0 15951819
    306 2bo7:E (2.95) BS01 GDP 2.4.1.269 GO:0016740 ... Q9RFR0 15951819
    307 2bo7:F (2.95) BS01 GDP 2.4.1.269 GO:0016740 ... Q9RFR0 15951819
    308 2bo7:G (2.95) BS01 GDP 2.4.1.269 GO:0016740 ... Q9RFR0 15951819
    309 2bo7:H (2.95) BS01 GDP 2.4.1.269 GO:0016740 ... Q9RFR0 15951819
    310 2bo7:I (2.95) BS01 GDP 2.4.1.269 GO:0016740 ... Q9RFR0 15951819
    311 2bo7:J (2.95) BS01 GDP 2.4.1.269 GO:0016740 ... Q9RFR0 15951819
    312 2bov:A (2.66) BS01 GDP 3.6.5.2 GO:0001843 ... P11233 15809419
    313 2btq:A (3.2) BS01 GDP ? GO:0000226 ... Q8GCC5 15967998
    314 2c03:A (1.24) BS01 GDP 3.6.5.4 GO:0003924 ... O07347 18931411
    315 2c03:B (1.24) BS01 GDP 3.6.5.4 GO:0003924 ... O07347 18931411
    316 2c2h:A (1.85) BS01 GDP 3.6.5.2 GO:0003924 ... P60763 N/A
    317 2c2h:A (1.85) BS02 GDP 3.6.5.2 GO:0003924 ... P60763 N/A
    318 2c2h:A (1.85) BS03 GDP 3.6.5.2 GO:0003924 ... P60763 N/A
    319 2c2h:A (1.85) BS04 GDP 3.6.5.2 GO:0003924 ... P60763 N/A
    320 2c2h:B (1.85) BS01 GDP 3.6.5.2 GO:0003924 ... P60763 N/A
    321 2c2h:B (1.85) BS02 GDP 3.6.5.2 GO:0003924 ... P60763 N/A
    322 2c2h:B (1.85) BS03 GDP 3.6.5.2 GO:0003924 ... P60763 N/A
    323 2ce2:X (1.0) BS01 GDP 3.6.5.2 GO:0003924 ... P01112 16698776
    324 2cjw:A (2.1) BS01 GDP ? GO:0003924 ... P55040 17107948 MOAD: Kd=2.5uM
    325 2cjw:B (2.1) BS01 GDP ? GO:0003924 ... P55040 17107948 MOAD: Kd=2.5uM
    326 2cld:X (1.22) BS01 GDP 3.6.5.2 GO:0003924 ... P01112 16698776
    327 2cnw:A (2.39) BS01 GDP 3.6.5.4 GO:0003924 ... O07347 16780874
    328 2cnw:B (2.39) BS01 GDP 3.6.5.4 GO:0003924 ... O07347 16780874
    329 2cnw:C (2.39) BS01 GDP 3.6.5.4 GO:0003924 ... O07347 16780874
    330 2cnw:D (2.39) BS01 GDP 3.6.5.4 GO:0003924 ... P83749 16780874
    331 2cnw:D (2.39) BS02 GDP 3.6.5.4 GO:0003924 ... P83749 16780874
    332 2cnw:E (2.39) BS01 GDP 3.6.5.4 GO:0003924 ... P83749 16780874
    333 2cnw:E (2.39) BS02 GDP 3.6.5.4 GO:0003924 ... P83749 16780874
    334 2cnw:F (2.39) BS01 GDP 3.6.5.4 GO:0003924 ... P83749 16780874
    335 2cnw:F (2.39) BS02 GDP 3.6.5.4 GO:0003924 ... P83749 16780874
    336 2cvw:A (2.4) BS02 GDP 1.17.4.1 GO:0000166 ... P21524 16537479
    337 2cxx:A (1.7) BS01 GDP ? GO:0005525 ... O57939 N/A
    338 2cxx:B (1.7) BS01 GDP ? GO:0005525 ... O57939 N/A
    339 2cxx:C (1.7) BS01 GDP ? GO:0005525 ... O57939 N/A
    340 2dby:A (1.76) BS01 GDP ? GO:0005524 ... Q5SJ29 N/A
    341 2dcu:A (3.4) BS03 GDP 3.6.5.3 GO:0000049 ... Q8U082 16924118
    342 2dgn:A (2.4) BS03 GDP 6.3.4.4 GO:0000166 ... P28650 16981730
    343 2dpx:A (1.8) BS01 GDP 3.6.5.2 GO:0003924 ... P55042 16866878
    344 2dpx:B (1.8) BS01 GDP 3.6.5.2 GO:0003924 ... P55042 16866878
    345 2dxe:A (1.7) BS01 GDP 2.7.4.6 GO:0004550 ... O58429 N/A
    346 2dyk:A (1.96) BS01 GDP ? GO:0005525 ... Q5SIH8 N/A
    347 2dyk:B (1.96) BS01 GDP ? GO:0005525 ... Q5SIH8 N/A
    348 2dyk:B (1.96) BS02 GDP ? GO:0005525 ... Q5SIH8 N/A
    349 2e1r:A (3.15) BS02 GDP 3.6.5.- GO:0003746 ... P32324 17082187
    350 2e87:A (2.35) BS01 GDP ? GO:0003723 ... O59046 N/A
    351 2e9s:A (1.78) BS02 GDP 3.6.5.2 GO:0003924 ... Q9NRW1 N/A
    352 2e9s:B (1.78) BS01 GDP 3.6.5.2 GO:0003924 ... Q9NRW1 N/A
    353 2e9s:C (1.78) BS01 GDP 3.6.5.2 GO:0003924 ... Q9NRW1 N/A
    354 2efc:B (2.09) BS01 GDP ? GO:0003924 ... Q9SN68 20833725
    355 2efc:D (2.09) BS01 GDP ? GO:0003924 ... Q9SN68 20833725
    356 2efg:A (2.6) BS01 GDP ? GO:0003746 ... Q5SHN5 8070396
    357 2efh:B (2.1) BS01 GDP ? GO:0003924 ... Q9SN68 20833725
    358 2efh:D (2.1) BS01 GDP ? GO:0003924 ... Q9SN68 20833725
    359 2erx:A (1.65) BS02 GDP ? GO:0003924 ... Q96HU8 N/A
    360 2erx:B (1.65) BS02 GDP ? GO:0003924 ... Q96HU8 N/A
    361 2ery:A (1.7) BS01 GDP 3.6.5.- GO:0003924 ... P62070 N/A
    362 2ery:B (1.7) BS01 GDP 3.6.5.- GO:0003924 ... P62070 N/A
    363 2f7s:A (2.7) BS01 GDP 3.6.5.2 GO:0003924 ... O00194 N/A
    364 2f7s:B (2.7) BS01 GDP 3.6.5.2 GO:0003924 ... O00194 N/A
    365 2f9l:A (1.55) BS01 GDP 3.6.5.2 GO:0001881 ... Q15907 16545962
    366 2fa9:A (2.5) BS01 GDP 3.6.5.2 GO:0003400 ... Q9QVY3 N/A
    367 2fa9:B (2.5) BS01 GDP 3.6.5.2 GO:0003400 ... Q9QVY3 N/A
    368 2fah:A (2.09) BS01 GDP 4.1.1.32 GO:0004611 ... P21642 16819824
    369 2fah:B (2.09) BS01 GDP 4.1.1.32 GO:0004611 ... P21642 16819824
    370 2fah:C (2.09) BS02 GDP 4.1.1.32 GO:0004611 ... P21642 16819824
    371 2fah:D (2.09) BS03 GDP 4.1.1.32 GO:0004611 ... P21642 16819824
    372 2fe4:A (2.3) BS02 GDP 3.6.5.2 GO:0003924 ... Q9NRW1 16790928
    373 2fmx:A (1.82) BS01 GDP 3.6.5.2 GO:0003400 ... Q9QVY3 16899220
    374 2fmx:B (1.82) BS01 GDP 3.6.5.2 GO:0003400 ... Q9QVY3 16899220
    375 2fn4:A (1.65) BS01 GDP 3.6.5.- GO:0003924 ... P10301 N/A
    376 2fol:A (2.631) BS01 GDP 3.6.5.2 GO:0003924 ... P62820 N/A
    377 2fpg:B (2.96) BS01 GDP 6.2.1.4 GO:0003824 ... P53590 16481318
    378 2fv8:A (1.9) BS01 GDP ? GO:0000281 ... P62745 N/A
    379 2fx3:A (3.4) BS01 GDP ? GO:0003723 ... P0CE47 16552145
    380 2g0n:A (1.9) BS01 GDP 3.6.5.2 GO:0003924 ... P60763 N/A
    381 2g0n:B (1.9) BS01 GDP 3.6.5.2 GO:0003924 ... P60763 N/A
    382 2g3y:A (2.4) BS01 GDP ? GO:0003924 ... P55040 N/A
    383 2g77:B (2.26) BS02 GDP ? GO:0003924 ... O35963 16855591
    384 2g83:A (2.8) BS04 GDP ? GO:0003924 ... P63096 16981699 PDBbind: -logKd/Ki=5.92, Kd=1.2uM
    385 2g83:B (2.8) BS04 GDP ? GO:0003924 ... P63096 16981699
    386 2gao:A (2.0) BS01 GDP 3.6.5.2 GO:0003400 ... Q9NR31 N/A
    387 2gao:B (2.0) BS01 GDP 3.6.5.2 GO:0003400 ... Q9NR31 N/A
    388 2gcn:A (1.85) BS02 GDP ? GO:0000281 ... P08134 17497936
    389 2gcq:A (2.0) BS03 GDP 6.3.4.4 GO:0000166 ... P0A7D4 16981730
    390 2gek:A (2.4) BS01 GDP 2.4.1.345 GO:0004377 ... A0QWG6 17510062 PDBbind: -logKd/Ki=7.52, Kd=0.03uM
    391 2gf0:A (1.9) BS01 GDP ? GO:0003924 ... O95057 N/A
    392 2gf0:B (1.9) BS01 GDP ? GO:0003924 ... O95057 N/A
    393 2gf0:C (1.9) BS01 GDP ? GO:0003924 ... O95057 N/A
    394 2gf0:D (1.9) BS01 GDP ? GO:0003924 ... O95057 N/A
    395 2gf9:A (1.53) BS01 GDP ? GO:0003924 ... O95716 N/A
    396 2gj8:A (1.7) BS04 GDP 3.6.-.- GO:0005525 ... P25522 16763562
    397 2gj8:B (1.7) BS04 GDP 3.6.-.- GO:0005525 ... P25522 16763562
    398 2gj8:C (1.7) BS04 GDP 3.6.-.- GO:0005525 ... P25522 16763562
    399 2gj8:D (1.7) BS04 GDP 3.6.-.- GO:0005525 ... P25522 16763562
    400 2gj9:A (2.0) BS03 GDP 3.6.-.- GO:0005525 ... P25522 16763562

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218