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BioLiP
Download all results in tab-seperated text for 1002 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    201 3a2m:A (1.84) BS01 FRU 3.8.1.5 GO:0003824 ... P59337 20645368
    202 3a2m:A (1.84) BS02 FRU 3.8.1.5 GO:0003824 ... P59337 20645368
    203 3a2m:B (1.84) BS02 FRU 3.8.1.5 GO:0003824 ... P59337 20645368
    204 3a2s:X (2.2) BS02 FRU ? GO:0006811 ... Q5RT80 20351243
    205 3ao5:B (1.8) BS02 FRU 3.1.13.2
    3.1.26.13
    GO:0003676 ... Q72498 21275048
    206 3byn:A (2.1) BS01 FRU 2.4.1.10 GO:0009758 ... P05655 N/A
    207 3cx5:O (1.9) BS02 FRU 7.1.1.8 GO:0009055 ... P07143 18390544
    208 3cxh:O (2.5) BS02 FRU 7.1.1.8 GO:0009055 ... P07143 18390544
    209 3czk:A (2.2) BS02 FRU 3.2.1.48 GO:0005975 ... Q6UVM5 18565544
    210 3e37:B (1.8) BS02 FRU 2.5.1.58 GO:0003824 ... P49356 19246009
    211 3eyz:A (2.1) BS04 FRU 2.7.7.7 GO:0003676 ... P52026 20152155
    212 3ez5:A (1.9) BS04 FRU 2.7.7.7 GO:0003676 ... P52026 20152155
    213 3ez5:D (1.9) BS04 FRU 2.7.7.7 GO:0003676 ... P52026 20152155
    214 3fit:A (2.4) BS01 FRU 2.7.7.51
    3.6.1.29
    3.6.2.1
    3.9.1.-
    GO:0000166 ... P49789 9261067
    215 3h6z:A (2.8) BS03 FRU ? GO:0005634 ... Q9VK33 19494831
    216 3h6z:A (2.8) BS04 FRU ? GO:0005634 ... Q9VK33 19494831
    217 3h6z:B (2.8) BS03 FRU ? GO:0005634 ... Q9VK33 19494831
    218 3h83:A (2.06) BS01 FRU N/A GO:0004422 ... N/A N/A
    219 3h83:A (2.06) BS03 FRU N/A GO:0004422 ... N/A N/A
    220 3hl3:A (2.76) BS02 FRU 2.7.7.24 GO:0008879 ... A0A6L8PCC3 N/A
    221 3hp6:A (1.81) BS04 FRU 2.7.7.7 GO:0003676 ... Q5KWC1 21454515
    222 3hp6:D (1.81) BS04 FRU 2.7.7.7 GO:0003676 ... Q5KWC1 21454515
    223 3hp8:A (2.0) BS02 FRU ? N/A Q5MK11
    Q7S6U4
    19639634
    224 3hp8:A (2.0) BS04 FRU ? N/A Q5MK11
    Q7S6U4
    19639634
    225 3hp8:B (2.0) BS02 FRU ? N/A Q5MK11
    Q7S6U4
    19639634
    226 3hp8:B (2.0) BS04 FRU ? N/A Q5MK11
    Q7S6U4
    19639634
    227 3hpi:A (2.0) BS02 FRU ? GO:0005515 ... P0AEX9 20147285
    228 3hpi:B (2.0) BS02 FRU ? GO:0005515 ... P0AEX9 20147285
    229 3hpo:A (1.75) BS04 FRU 2.7.7.7 GO:0000166 ... D9N168 21454515
    230 3ht3:A (1.7) BS04 FRU 2.7.7.7 GO:0000166 ... D9N168 21454515
    231 3ht3:D (1.7) BS04 FRU 2.7.7.7 GO:0000166 ... D9N168 21454515
    232 3ht3:D (1.7) BS06 FRU 2.7.7.7 GO:0000166 ... D9N168 21454515
    233 3hz3:A (2.22) BS02 FRU 2.4.1.5 GO:0009250 ... Q5SBN3 21118988
    234 3ife:A (1.55) BS01 FRU 3.4.11.4 GO:0004177 ... Q81WU4 N/A
    235 3it9:A (2.1) BS01 FRU 3.4.16.4 GO:0004180 ... P08506 19807181
    236 3it9:A (2.1) BS03 FRU 3.4.16.4 GO:0004180 ... P08506 19807181
    237 3iwo:A (1.9) BS02 FRU 3.5.2.6 GO:0008800 ... P00811 19913034
    238 3iwo:B (1.9) BS02 FRU 3.5.2.6 GO:0008800 ... P00811 19913034
    239 3iwo:B (1.9) BS03 FRU 3.5.2.6 GO:0008800 ... P00811 19913034
    240 3js8:A (1.54) BS01 FRU 1.1.3.6 GO:0000166 ... B5MGF8 20102741
    241 3kb8:A (2.09) BS01 FRU 2.4.2.8 GO:0000166 ... B9ZW32 N/A
    242 3kf3:A (1.9) BS01 FRU 3.2.1.26 GO:0004553 ... P24133 20181943
    243 3kf3:B (1.9) BS01 FRU 3.2.1.26 GO:0004553 ... P24133 20181943
    244 3l3v:A (2.0) BS01 FRU 3.1.13.2
    3.1.26.13
    GO:0003676 ... Q72498 20227411
    245 3ldk:A (2.2) BS02 FRU ? GO:0004553 ... Q1W3Z7 N/A
    246 3ldr:A (2.1) BS02 FRU ? GO:0004553 ... Q1W3Z7 N/A
    247 3ldr:A (2.1) BS03 FRU ? GO:0004553 ... Q1W3Z7 N/A
    248 3lem:A (2.1) BS01 FRU ? GO:0004553 ... Q1W3Z7 N/A
    249 3lem:A (2.1) BS02 FRU ? GO:0004553 ... Q1W3Z7 N/A
    250 3lih:A (2.2) BS01 FRU ? GO:0004553 ... Q1W3Z7 20466731
    251 3lm9:A (2.45) BS01 FRU 2.7.1.4 GO:0000272 ... O05510 21185308
    252 3lrm:A (2.7) BS01 FRU 3.2.1.22 GO:0004553 ... P04824 20592022
    253 3lrm:B (2.7) BS02 FRU 3.2.1.22 GO:0004553 ... P04824 20592022
    254 3lrm:C (2.7) BS02 FRU 3.2.1.22 GO:0004553 ... P04824 20592022
    255 3lxy:A (1.7) BS01 FRU 1.1.1.262 GO:0000287 ... P58719 N/A
    256 3moo:A (1.71) BS01 FRU 1.14.14.18 GO:0004392 ... Q54AI1 20806922
    257 3moo:B (1.71) BS01 FRU 1.14.14.18 GO:0004392 ... Q54AI1 20806922
    258 3mpb:A (1.91) BS02 FRU ? GO:0016853 ... Q8X5Q7 20615418
    259 3mpb:B (1.91) BS01 FRU ? GO:0016853 ... Q8X5Q7 20615418
    260 3nbv:A (2.3) BS02 FRU 2.7.1.3 GO:0004454 ... P50053 21033679
    261 3nfm:A (2.5) BS01 FRU 3.2.2.22 GO:0000166 ... D9J2T9 N/A
    262 3obv:A (2.75) BS02 FRU ? GO:0003779 ... O08808 20927343
    263 3obv:C (2.75) BS01 FRU ? GO:0003779 ... O08808 20927343
    264 3ovn:A (1.95) BS01 FRU 3.1.13.2
    3.1.26.13
    GO:0003676 ... Q72498 21275048
    265 3ovn:B (1.95) BS02 FRU 3.1.13.2
    3.1.26.13
    GO:0003676 ... Q72498 21275048
    266 3pij:A (1.8) BS01 FRU 3.2.1.26 GO:0004553 ... A2TLS9 21418142
    267 3pij:B (1.8) BS01 FRU 3.2.1.26 GO:0004553 ... A2TLS9 21418142
    268 3q73:A (2.3) BS01 FRU N/A GO:0008318 ... N/A 21816822
    269 3q73:B (2.3) BS02 FRU N/A GO:0003824 ... N/A 21816822
    270 3q7a:A (2.0) BS01 FRU N/A GO:0008318 ... N/A 21816822
    271 3q7a:B (2.0) BS02 FRU N/A GO:0003824 ... N/A 21816822
    272 3q7f:A (2.2) BS01 FRU N/A GO:0008318 ... N/A 21816822
    273 3q7f:B (2.2) BS02 FRU N/A GO:0003824 ... N/A 21816822
    274 3qgv:A (2.1) BS05 FRU N/A GO:0004553 ... N/A N/A
    275 3qph:A (2.992) BS02 FRU ? GO:0003677 ... Q9HGZ9 23576322
    276 3qyq:A (1.8) BS02 FRU 4.1.2.4 GO:0003824 ... A0A7J6KBZ0 25284756
    277 3qyq:B (1.8) BS01 FRU 4.1.2.4 GO:0003824 ... A0A7J6KBZ0 25284756
    278 3r1b:A (3.0) BS02 FRU 1.14.14.1 GO:0004497 ... P00178 21510666
    279 3r1b:D (3.0) BS02 FRU 1.14.14.1 GO:0004497 ... P00178 21510666
    280 3rwk:X (2.1) BS04 FRU 3.2.1.7 GO:0004553 ... O94220 22750808
    281 3rwk:X (2.1) BS05 FRU 3.2.1.7 GO:0004553 ... O94220 22750808
    282 3s27:A (2.91) BS02 FRU 2.4.1.13 GO:0001666 ... P49040 21865170
    283 3s27:B (2.91) BS02 FRU 2.4.1.13 GO:0001666 ... P49040 21865170
    284 3s27:C (2.91) BS02 FRU 2.4.1.13 GO:0001666 ... P49040 21865170
    285 3s27:D (2.91) BS02 FRU 2.4.1.13 GO:0001666 ... P49040 21865170
    286 3s27:E (2.91) BS02 FRU 2.4.1.13 GO:0001666 ... P49040 21865170
    287 3s27:F (2.91) BS02 FRU 2.4.1.13 GO:0001666 ... P49040 21865170
    288 3s27:G (2.91) BS02 FRU 2.4.1.13 GO:0001666 ... P49040 21865170
    289 3s27:H (2.91) BS02 FRU 2.4.1.13 GO:0001666 ... P49040 21865170
    290 3s29:A (2.85) BS02 FRU 2.4.1.13 GO:0001666 ... P49040 21865170
    291 3s29:B (2.85) BS02 FRU 2.4.1.13 GO:0001666 ... P49040 21865170
    292 3s29:C (2.85) BS02 FRU 2.4.1.13 GO:0001666 ... P49040 21865170
    293 3s29:D (2.85) BS02 FRU 2.4.1.13 GO:0001666 ... P49040 21865170
    294 3s29:E (2.85) BS02 FRU 2.4.1.13 GO:0001666 ... P49040 21865170
    295 3s29:F (2.85) BS02 FRU 2.4.1.13 GO:0001666 ... P49040 21865170
    296 3s29:G (2.85) BS02 FRU 2.4.1.13 GO:0001666 ... P49040 21865170
    297 3s29:H (2.85) BS02 FRU 2.4.1.13 GO:0001666 ... P49040 21865170
    298 3s7z:B (2.002) BS02 FRU ? GO:0006520 ... Q8ZJZ9 N/A
    299 3so3:B (2.1) BS01 FRU N/A N/A N/A 22154938
    300 3sp3:A (1.801) BS02 FRU 3.2.1.17 GO:0003796 ... P00698 N/A
    301 3t6u:A (2.213) BS02 FRU 3.2.1.17 GO:0003796 ... P00698 N/A
    302 3tan:A (1.53) BS04 FRU N/A GO:0003676 ... N/A 22006298
    303 3tap:A (1.655) BS04 FRU N/A GO:0003676 ... N/A 22006298
    304 3taq:A (1.65) BS04 FRU N/A GO:0003676 ... N/A 22006298
    305 3tar:A (1.6) BS04 FRU N/A GO:0003676 ... N/A 22006298
    306 3u14:A (2.24) BS01 FRU 3.2.1.26 GO:0004553 ... E5D0X5 22511773
    307 3u14:A (2.24) BS02 FRU 3.2.1.26 GO:0004553 ... E5D0X5 22511773
    308 3u14:A (2.24) BS03 FRU 3.2.1.26 GO:0004553 ... E5D0X5 22511773
    309 3u14:A (2.24) BS04 FRU 3.2.1.26 GO:0004553 ... E5D0X5 22511773
    310 3u14:B (2.24) BS01 FRU 3.2.1.26 GO:0004553 ... E5D0X5 22511773
    311 3u14:B (2.24) BS02 FRU 3.2.1.26 GO:0004553 ... E5D0X5 22511773
    312 3u14:B (2.24) BS03 FRU 3.2.1.26 GO:0004553 ... E5D0X5 22511773
    313 3u14:B (2.24) BS04 FRU 3.2.1.26 GO:0004553 ... E5D0X5 22511773
    314 3u75:A (2.68) BS01 FRU 3.2.1.26 GO:0004553 ... E5D0X5 22511773
    315 3u75:A (2.68) BS02 FRU 3.2.1.26 GO:0004553 ... E5D0X5 22511773
    316 3u75:A (2.68) BS03 FRU 3.2.1.26 GO:0004553 ... E5D0X5 22511773
    317 3u75:B (2.68) BS01 FRU 3.2.1.26 GO:0004553 ... E5D0X5 22511773
    318 3u75:B (2.68) BS02 FRU 3.2.1.26 GO:0004553 ... E5D0X5 22511773
    319 3u75:C (2.68) BS01 FRU 3.2.1.26 GO:0004553 ... E5D0X5 22511773
    320 3u75:C (2.68) BS02 FRU 3.2.1.26 GO:0004553 ... E5D0X5 22511773
    321 3u75:D (2.68) BS01 FRU 3.2.1.26 GO:0004553 ... E5D0X5 22511773
    322 3u75:D (2.68) BS02 FRU 3.2.1.26 GO:0004553 ... E5D0X5 22511773
    323 3uer:A (2.1) BS03 FRU 2.4.1.4 GO:0005975 ... Q1J0W0 22210773
    324 3ugg:A (2.9) BS01 FRU 3.2.1.26 GO:0004553 ... E3PQS3 22098191
    325 3ugg:A (2.9) BS02 FRU 3.2.1.26 GO:0004553 ... E3PQS3 22098191
    326 3ugg:B (2.9) BS01 FRU 3.2.1.26 GO:0004553 ... E3PQS3 22098191
    327 3ugg:B (2.9) BS02 FRU 3.2.1.26 GO:0004553 ... E3PQS3 22098191
    328 3ugh:B (2.9) BS01 FRU 3.2.1.26 GO:0004553 ... E3PQS3 22098191
    329 3vf1:A (2.473) BS01 FRU ? GO:0005506 ... Q2N410 22573333
    330 3vf1:B (2.473) BS01 FRU ? GO:0005506 ... Q2N410 22573333
    331 3vq7:A (1.63) BS02 FRU 3.1.13.2
    3.1.26.13
    GO:0003676 ... Q72498 23139382
    332 3vq7:B (1.63) BS02 FRU 3.1.13.2
    3.1.26.13
    GO:0003676 ... Q72498 23139382
    333 3vqa:A (1.9) BS02 FRU 3.1.13.2
    3.1.26.13
    GO:0003676 ... Q72498 23139382
    334 3vqa:B (1.9) BS02 FRU 3.1.13.2
    3.1.26.13
    GO:0003676 ... Q72498 23139382
    335 3vqq:B (2.0) BS01 FRU 3.1.13.2
    3.1.26.13
    GO:0003676 ... Q72498 23139382
    336 3vss:A (1.97) BS01 FRU 3.2.1.26 GO:0009758 ... Q8VW87 23040392
    337 3vss:A (1.97) BS02 FRU 3.2.1.26 GO:0009758 ... Q8VW87 23040392
    338 3vss:A (1.97) BS03 FRU 3.2.1.26 GO:0009758 ... Q8VW87 23040392
    339 3vss:A (1.97) BS04 FRU 3.2.1.26 GO:0009758 ... Q8VW87 23040392
    340 3w9t:B (2.9) BS06 FRU ? GO:0000287 ... Q868M7 N/A
    341 3w9t:D (2.9) BS05 FRU ? GO:0000287 ... Q868M7 N/A
    342 3w9t:E (2.9) BS02 FRU ? GO:0000287 ... Q868M7 N/A
    343 3w9t:E (2.9) BS04 FRU ? GO:0000287 ... Q868M7 N/A
    344 4b1l:A (1.65) BS01 FRU 3.2.1.80 GO:0016787 ... P05656 23213210 MOAD: Kd~10mM
    345 4b1m:A (1.1) BS01 FRU 3.2.1.80 GO:0016787 ... P05656 23213210
    346 4b1m:A (1.1) BS02 FRU 3.2.1.80 GO:0016787 ... P05656 23213210
    347 4b1m:B (1.1) BS01 FRU 3.2.1.80 GO:0016787 ... P05656 23213210
    348 4b1m:B (1.1) BS02 FRU 3.2.1.80 GO:0016787 ... P05656 23213210
    349 4b1m:C (1.1) BS01 FRU 3.2.1.80 GO:0016787 ... P05656 23213210
    350 4b1m:C (1.1) BS02 FRU 3.2.1.80 GO:0016787 ... P05656 23213210
    351 4b9l:A (2.05) BS04 FRU 2.7.7.7 GO:0000166 ... E1C9K5 23685671
    352 4b9n:A (2.2) BS04 FRU 2.7.7.7 GO:0000166 ... E1C9K5 23685671
    353 4b9s:A (1.73) BS03 FRU 2.7.7.7 GO:0000166 ... E1C9K5 23685671
    354 4bga:A (2.6) BS01 FRU ? GO:0000166 ... Q8TX37 24311585
    355 4bga:C (2.6) BS02 FRU ? GO:0000166 ... Q8TX37 24311585
    356 4bga:D (2.6) BS01 FRU ? GO:0000166 ... Q8TX37 24311585
    357 4c3x:B (2.0) BS01 FRU 1.3.99.4 GO:0000166 ... Q9RA02 24165124
    358 4c3x:C (2.0) BS02 FRU 1.3.99.4 GO:0000166 ... Q9RA02 24165124
    359 4c3x:D (2.0) BS01 FRU 1.3.99.4 GO:0000166 ... Q9RA02 24165124
    360 4c3x:D (2.0) BS04 FRU 1.3.99.4 GO:0000166 ... Q9RA02 24165124
    361 4c3x:E (2.0) BS02 FRU 1.3.99.4 GO:0000166 ... Q9RA02 24165124
    362 4c3x:F (2.0) BS01 FRU 1.3.99.4 GO:0000166 ... Q9RA02 24165124
    363 4c3x:F (2.0) BS04 FRU 1.3.99.4 GO:0000166 ... Q9RA02 24165124
    364 4c3x:G (2.0) BS02 FRU 1.3.99.4 GO:0000166 ... Q9RA02 24165124
    365 4c3x:H (2.0) BS01 FRU 1.3.99.4 GO:0000166 ... Q9RA02 24165124
    366 4c3x:H (2.0) BS04 FRU 1.3.99.4 GO:0000166 ... Q9RA02 24165124
    367 4d47:A (2.77) BS01 FRU 2.4.1.10 GO:0009758 ... A0A0M3KKU6 26208466
    368 4d47:B (2.77) BS01 FRU 2.4.1.10 GO:0009758 ... A0A0M3KKU6 26208466
    369 4d47:C (2.77) BS01 FRU 2.4.1.10 GO:0009758 ... A0A0M3KKU6 26208466
    370 4d47:D (2.77) BS01 FRU 2.4.1.10 GO:0009758 ... A0A0M3KKU6 26208466
    371 4d47:E (2.77) BS01 FRU 2.4.1.10 GO:0009758 ... A0A0M3KKU6 26208466
    372 4d47:F (2.77) BS01 FRU 2.4.1.10 GO:0009758 ... A0A0M3KKU6 26208466
    373 4d47:G (2.77) BS01 FRU 2.4.1.10 GO:0009758 ... A0A0M3KKU6 26208466
    374 4d47:H (2.77) BS01 FRU 2.4.1.10 GO:0009758 ... A0A0M3KKU6 26208466
    375 4dwr:A (1.48) BS02 FRU 3.1.-.-
    6.5.1.8
    GO:0006396 ... O59245 22949672
    376 4dwr:B (1.48) BS02 FRU 3.1.-.-
    6.5.1.8
    GO:0006396 ... O59245 22949672
    377 4dwr:C (1.48) BS02 FRU 3.1.-.-
    6.5.1.8
    GO:0006396 ... O59245 22949672
    378 4f2r:A (1.63) BS04 FRU 2.7.7.7 GO:0003676 ... Q5KWC1 N/A
    379 4f2r:D (1.63) BS04 FRU 2.7.7.7 GO:0003676 ... Q5KWC1 N/A
    380 4f2s:A (1.651) BS04 FRU 2.7.7.7 GO:0003676 ... Q5KWC1 N/A
    381 4f2s:D (1.651) BS04 FRU 2.7.7.7 GO:0003676 ... Q5KWC1 N/A
    382 4ffg:A (2.3) BS01 FRU 4.2.2.16 GO:0004553 ... Q9KJD0 22810228
    383 4ffg:A (2.3) BS02 FRU 4.2.2.16 GO:0004553 ... Q9KJD0 22810228
    384 4ffg:B (2.3) BS01 FRU 4.2.2.16 GO:0004553 ... Q9KJD0 22810228
    385 4ffg:C (2.3) BS01 FRU 4.2.2.16 GO:0004553 ... Q9KJD0 22810228
    386 4ffg:C (2.3) BS02 FRU 4.2.2.16 GO:0004553 ... Q9KJD0 22810228
    387 4ffg:D (2.3) BS01 FRU 4.2.2.16 GO:0004553 ... Q9KJD0 22810228
    388 4ffh:A (2.2) BS02 FRU 4.2.2.16 GO:0004553 ... Q9KJD0 22810228
    389 4ffh:A (2.2) BS03 FRU 4.2.2.16 GO:0004553 ... Q9KJD0 22810228
    390 4ffh:B (2.2) BS02 FRU 4.2.2.16 GO:0004553 ... Q9KJD0 22810228
    391 4ffh:B (2.2) BS03 FRU 4.2.2.16 GO:0004553 ... Q9KJD0 22810228
    392 4ffh:C (2.2) BS01 FRU 4.2.2.16 GO:0004553 ... Q9KJD0 22810228
    393 4ffh:D (2.2) BS01 FRU 4.2.2.16 GO:0004553 ... Q9KJD0 22810228
    394 4ffi:A (2.3) BS01 FRU 4.2.2.16 GO:0004553 ... Q9KJD0 22810228
    395 4ffi:A (2.3) BS02 FRU 4.2.2.16 GO:0004553 ... Q9KJD0 22810228
    396 4ffi:A (2.3) BS03 FRU 4.2.2.16 GO:0004553 ... Q9KJD0 22810228
    397 4ffi:B (2.3) BS01 FRU 4.2.2.16 GO:0004553 ... Q9KJD0 22810228
    398 4ffi:B (2.3) BS02 FRU 4.2.2.16 GO:0004553 ... Q9KJD0 22810228
    399 4ffi:B (2.3) BS03 FRU 4.2.2.16 GO:0004553 ... Q9KJD0 22810228
    400 4ffi:B (2.3) BS04 FRU 4.2.2.16 GO:0004553 ... Q9KJD0 22810228

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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