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BioLiP
Download all results in tab-seperated text for 26 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1flr:H (1.85) BS01 FLU ? N/A P01865 8637844 PDBbind: -logKd/Ki=10.00, Kd=0.1nM
    2 1flr:L (1.85) BS01 FLU N/A N/A N/A 8637844 MOAD: Kd=0.1nM
    PDBbind: -logKd/Ki=10.00, Kd=0.1nM
    3 1n0s:A (2.0) BS01 FLU ? GO:0000302 ... P09464 12945055 MOAD: Kd=35.2nM
    PDBbind: -logKd/Ki=7.45, Kd=35.2nM
    4 1n0s:B (2.0) BS01 FLU ? GO:0000302 ... P09464 12945055 MOAD: Kd=35.2nM
    5 1t66:C (2.3) BS01 FLU ? GO:0046872 ... Q65ZC0 15178254
    6 1t66:D (2.3) BS01 FLU ? N/A Q91Z05 15178254
    7 1t66:H (2.3) BS01 FLU ? N/A Q91Z05 15178254
    8 1t66:L (2.3) BS01 FLU ? GO:0046872 ... Q65ZC0 15178254
    9 1x9q:A (1.5) BS01 FLU N/A N/A N/A 15465055 MOAD: Kd=0.27pM
    10 2nmv:A (2.95) BS02 FLU 3.1.-.- GO:0003677 ... P37954 17097086
    11 4fab:H (2.7) BS01 FLU ? N/A P01865 2508085 PDBbind: -logKd/Ki=8.06, Kd=8.8nM
    12 4fab:L (2.7) BS01 FLU N/A N/A N/A 2508085 PDBbind: -logKd/Ki=8.06, Kd=8.8nM
    13 4zs2:A (2.16) BS02 FLU 1.14.11.-
    1.14.11.53    		 GO:0001659 ... Q9C0B1 26457839 MOAD: ic50=3.23uM
    PDBbind: -logKd/Ki=5.49, IC50=3.23uM
    14 5dyo:A (2.36) BS01 FLU N/A N/A N/A 26756394 PDBbind: -logKd/Ki=10.21, Kd=61pM
    15 5dyo:B (2.36) BS01 FLU N/A N/A N/A 26756394 PDBbind: -logKd/Ki=10.21, Kd=61pM
    16 5dyo:B (2.36) BS02 FLU N/A N/A N/A 26756394 PDBbind: -logKd/Ki=10.21, Kd=61pM
    17 5dyo:H (2.36) BS01 FLU N/A N/A N/A 26756394
    18 5dyo:L (2.36) BS01 FLU N/A N/A N/A 26756394
    19 5dyo:L (2.36) BS02 FLU N/A N/A N/A 26756394
    20 5tsv:B (2.502) BS02 FLU ? GO:0016032 ... P12493 N/A
    21 5tsx:A (1.899) BS02 FLU ? GO:0016032 ... P12493 N/A
    22 5tsx:B (1.899) BS02 FLU ? GO:0016032 ... P12493 N/A
    23 5tsx:G (1.899) BS02 FLU ? GO:0016032 ... P12493 N/A
    24 5tsx:H (1.899) BS02 FLU ? GO:0016032 ... P12493 N/A
    25 6ayl:A (1.86) BS01 FLU ? GO:0005324 ... P15090 N/A
    26 6ayl:A (1.86) BS02 FLU ? GO:0005324 ... P15090 N/A
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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