Home Research COVID-19 Services Publications People Teaching Job Opening News Forum --> -->
Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
Download all results in tab-seperated text for 20 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

    • Sort results by
    << < 1 > >>
    Go to page

    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1cqe:A (3.1) BS02 FLP 1.14.99.1 GO:0004601 ... P05979 8121489 BindingDB: IC50=150nM, Ki=1000nM
    2 1cqe:B (3.1) BS02 FLP 1.14.99.1 GO:0004601 ... P05979 8121489 BindingDB: IC50=150nM, Ki=1000nM
    3 1dvt:A (1.9) BS01 FLP ? GO:0005179 ... P02766 10742177
    4 1eqh:A (2.7) BS02 FLP 1.14.99.1 GO:0004601 ... P05979 11318639 BindingDB: IC50=150nM, Ki=1000nM
    5 1eqh:B (2.7) BS02 FLP 1.14.99.1 GO:0004601 ... P05979 11318639 BindingDB: IC50=150nM, Ki=1000nM
    6 1r9o:A (2.0) BS02 FLP 1.14.14.1
    1.14.14.51
    1.14.14.52
    1.14.14.53    		 GO:0004497 ... P11712 15181000
    7 2ayl:A (2.0) BS02 FLP 1.14.99.1 GO:0001516 ... P05979 16421446 BindingDB: IC50=150nM, Ki=1000nM
    8 2ayl:B (2.0) BS02 FLP 1.14.99.1 GO:0001516 ... P05979 16421446 BindingDB: IC50=150nM, Ki=1000nM
    9 3n8w:A (2.75) BS02 FLP 1.14.99.1 GO:0001516 ... P05979 20669977 BindingDB: IC50=150nM, Ki=1000nM
    10 3n8z:A (2.9) BS02 FLP 1.14.99.1 GO:0001516 ... P05979 20669977 BindingDB: IC50=150nM, Ki=1000nM
    11 3n8z:B (2.9) BS02 FLP 1.14.99.1 GO:0001516 ... P05979 20669977 BindingDB: IC50=150nM, Ki=1000nM
    12 3pgh:A (2.5) BS02 FLP 1.14.99.1 GO:0001516 ... Q05769 8967954 BindingDB: IC50=500nM
    13 3pgh:B (2.5) BS02 FLP 1.14.99.1 GO:0001516 ... Q05769 8967954 BindingDB: IC50=500nM
    14 3pgh:C (2.5) BS02 FLP 1.14.99.1 GO:0001516 ... Q05769 8967954 BindingDB: IC50=500nM
    15 3pgh:D (2.5) BS02 FLP 1.14.99.1 GO:0001516 ... Q05769 8967954 BindingDB: IC50=500nM
    16 4for:A (1.58) BS04 FLP 3.4.21.- GO:0005576 ... P24627 N/A
    17 4jtq:A (1.6) BS01 FLP 1.-.-.-
    1.1.1.112
    1.1.1.209
    1.1.1.357
    1.1.1.53
    1.1.1.62
    1.3.1.20    		 GO:0004032 ... P52895 N/A BindingDB: IC50=32500nM
    18 4jtq:B (1.6) BS01 FLP 1.-.-.-
    1.1.1.112
    1.1.1.209
    1.1.1.357
    1.1.1.53
    1.1.1.62
    1.3.1.20    		 GO:0004032 ... P52895 N/A BindingDB: IC50=32500nM
    19 5jvz:A (2.62) BS01 FLP 1.14.99.1 GO:0001516 ... Q05769 27756840 BindingDB: IC50=500nM
    20 5jvz:B (2.62) BS01 FLP 1.14.99.1 GO:0001516 ... Q05769 27756840 BindingDB: IC50=500nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

    • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218