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BioLiP
Download all results in tab-seperated text for 12 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 2wej:A (1.45) BS02 FB2 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 19882701 MOAD: Kd=839nM
    PDBbind: -logKd/Ki=6.08, Kd=839nM
    BindingDB: Ki=1103nM, Kd=1149700nM
    2 4jsa:A (1.5) BS02 FB2 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 23706138 MOAD: Ki=11uM
    PDBbind: -logKd/Ki=4.96, Ki=11uM
    BindingDB: Ki=1103nM, Kd=1149700nM
    3 4jsa:A (1.5) BS03 FB2 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 23706138 MOAD: Ki=11uM
    PDBbind: -logKd/Ki=4.96, Ki=11uM
    BindingDB: Ki=1103nM, Kd=1149700nM
    4 4jsz:A (1.9) BS02 FB2 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 23706138 MOAD: Ki=5000uM
    PDBbind: -logKd/Ki=2.30, Ki=5000uM
    BindingDB: Ki=1103nM, Kd=1149700nM
    5 4jsz:A (1.9) BS03 FB2 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 23706138 MOAD: Ki=5000uM
    PDBbind: -logKd/Ki=2.30, Ki=5000uM
    BindingDB: Ki=1103nM, Kd=1149700nM
    6 4yx4:A (1.01) BS02 FB2 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 26700575 MOAD: Kd=1073.4nM
    PDBbind: -logKd/Ki=5.97, Kd=1073.4nM
    BindingDB: Ki=1103nM, Kd=1149700nM
    7 5fzn:A (1.97) BS01 FB2 ? N/A Q9Z2X8 27031670
    8 5jad:A (2.05) BS01 FB2 3.1.1.47 GO:0003847 ... Q13093 27167608 MOAD: Kd=3.4mM
    BindingDB: IC50=>1000000nM, Kd=3400000nM
    9 5nya:A (1.2) BS02 FB2 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 29316128 MOAD: Ki=415.6nM
    PDBbind: -logKd/Ki=6.38, Ki=415.6nM
    BindingDB: Ki=1103nM, Kd=1149700nM
    10 6gdc:A (1.079) BS03 FB2 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 32027480 BindingDB: Ki=1103nM, Kd=1149700nM
    11 6gdc:A (1.079) BS04 FB2 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 32027480 BindingDB: Ki=1103nM, Kd=1149700nM
    12 6ld3:A (2.3) BS04 FB2 2.1.1.56
    2.1.1.57
    2.7.7.48
    3.4.21.91
    3.6.1.15
    3.6.4.13    		 GO:0003968 ... A0A024B7W1 32796069
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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