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BioLiP
Download all results in tab-seperated text for 18 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 6d8x:A (1.9) BS01 EDK ? GO:0003677 ... P37231 N/A BindingDB: Ki=1.4nM, EC50=6.2nM
    2 6d94:A (1.9) BS02 EDK ? GO:0003677 ... P37231 36469765 BindingDB: Ki=1.4nM, EC50=6.2nM
    3 6fzf:A (1.95) BS02 EDK ? GO:0003677 ... P37231 30651555 BindingDB: Ki=1.4nM, EC50=6.2nM
    4 6fzf:B (1.95) BS02 EDK ? GO:0003677 ... P37231 30651555 BindingDB: Ki=1.4nM, EC50=6.2nM
    5 6fzg:A (2.1) BS01 EDK ? GO:0003677 ... P37231 30651555 PDBbind: -logKd/Ki=6.55, Kd=0.28uM
    BindingDB: Ki=1.4nM, EC50=6.2nM
    6 6fzj:A (2.011) BS02 EDK ? GO:0003677 ... P37231 30651555 BindingDB: Ki=1.4nM, EC50=6.2nM
    7 6fzj:B (2.011) BS02 EDK ? GO:0003677 ... P37231 30651555 BindingDB: Ki=1.4nM, EC50=6.2nM
    8 6fzp:A (2.3) BS02 EDK ? GO:0003677 ... P37231 30651555 BindingDB: Ki=1.4nM, EC50=6.2nM
    9 6t1s:A (1.65) BS01 EDK ? GO:0003677 ... P37231 N/A BindingDB: EC50=130nM, Ki=0.049700nM
    10 6t1v:A (2.21) BS02 EDK ? GO:0003677 ... P37231 N/A BindingDB: EC50=130nM, Ki=0.049700nM
    11 6vzl:A (2.07) BS01 EDK ? GO:0003677 ... P37231 33713599 BindingDB: EC50=130nM, Ki=0.049700nM
    12 6vzl:B (2.07) BS01 EDK ? GO:0003677 ... P37231 33713599 BindingDB: EC50=130nM, Ki=0.049700nM
    13 7jqg:A (2.15) BS01 EDK ? GO:0003677 ... P37231 33713599 BindingDB: EC50=130nM, Ki=0.049700nM
    14 7jqg:B (2.15) BS01 EDK ? GO:0003677 ... P37231 33713599 BindingDB: EC50=130nM, Ki=0.049700nM
    15 7rle:A (2.5) BS02 EDK ? GO:0003677 ... P37231 36469765
    16 7rle:C (2.5) BS02 EDK ? GO:0003677 ... P37231 36469765
    17 9ck0:A (2.6) BS02 EDK N/A N/A P37231 N/A
    18 9cwn:A (2.7) BS02 EDK N/A N/A P37231 N/A
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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