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BioLiP
Download all results in tab-seperated text for 6 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1di8:A (2.2) BS01 DTQ 2.7.11.22 GO:0000082 ... P24941 10633045 MOAD: ic50=1uM
    PDBbind: -logKd/Ki=6.00, IC50=1uM
    BindingDB: IC50=1000nM
    2 3nyv:A (1.88) BS01 DTQ 2.7.11.17 GO:0004672 ... Q9BJF5 N/A
    3 4btk:A (2.0) BS01 DTQ 2.7.11.1 GO:0004672 ... Q5TCY1 24039150 MOAD: Kd=0.24uM
    PDBbind: -logKd/Ki=6.62, Kd=0.24uM
    BindingDB: Kd=240nM
    4 5amn:A (2.57) BS01 DTQ 2.7.10.1 GO:0004672 ... P07949 26874741 PDBbind: -logKd/Ki=8.35, IC50=4.5nM
    BindingDB: IC50=380nM
    5 6u0k:A (1.744) BS01 DTQ 2.7.11.1 GO:0004672 ... Q6IQ55 N/A
    6 6u0k:B (1.744) BS01 DTQ 2.7.11.1 GO:0004672 ... Q6IQ55 N/A
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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