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BioLiP
Download all results in tab-seperated text for 12 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1p6j:A (2.0) BS04 DP9 1.14.13.39 GO:0004517 ... P29476 14718923 MOAD: Ki=0.1uM
    BindingDB: Ki=100nM, IC50=640nM
    2 1p6j:B (2.0) BS05 DP9 1.14.13.39 GO:0004517 ... P29476 14718923 MOAD: Ki=0.1uM
    BindingDB: Ki=100nM, IC50=640nM
    3 1p6n:A (2.5) BS03 DP9 1.14.13.39 GO:0004517 ... P29473 14718923 MOAD: Ki=110uM
    BindingDB: IC50=29000nM, Ki=128000nM
    4 1p6n:B (2.5) BS05 DP9 1.14.13.39 GO:0004517 ... P29473 14718923 MOAD: Ki=110uM
    BindingDB: IC50=29000nM, Ki=128000nM
    5 1zzq:A (1.9) BS05 DP9 1.14.13.39 GO:0004517 ... P29476 16285725 MOAD: Ki=20uM
    BindingDB: Ki=100nM, IC50=640nM
    6 1zzq:B (1.9) BS06 DP9 1.14.13.39 GO:0004517 ... P29476 16285725 MOAD: Ki=20uM
    BindingDB: Ki=100nM, IC50=640nM
    7 1zzr:A (2.05) BS04 DP9 1.14.13.39 GO:0004517 ... P29476 16285725 MOAD: Ki=42uM
    BindingDB: Ki=100nM, IC50=640nM
    8 1zzr:B (2.05) BS05 DP9 1.14.13.39 GO:0004517 ... P29476 16285725 MOAD: Ki=42uM
    BindingDB: Ki=100nM, IC50=640nM
    9 1zzs:A (1.85) BS04 DP9 1.14.13.39 GO:0004517 ... P29473 16285725 MOAD: Ki=5.1uM
    BindingDB: IC50=29000nM, Ki=128000nM
    10 1zzs:B (1.85) BS05 DP9 1.14.13.39 GO:0004517 ... P29473 16285725 MOAD: Ki=5.1uM
    BindingDB: IC50=29000nM, Ki=128000nM
    11 1zzt:A (2.14) BS04 DP9 1.14.13.39 GO:0004517 ... P29473 16285725 MOAD: Ki=1.1uM
    BindingDB: IC50=29000nM, Ki=128000nM
    12 1zzt:B (2.14) BS05 DP9 1.14.13.39 GO:0004517 ... P29473 16285725 MOAD: Ki=1.1uM
    BindingDB: IC50=29000nM, Ki=128000nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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