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BioLiP
Download all results in tab-seperated text for 668 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1hk8:A (2.45) BS01 DGT 1.1.98.6 GO:0003824 ... P07071 12655046
    2 1hk8:A (2.45) BS02 DGT 1.1.98.6 GO:0003824 ... P07071 12655046
    3 1s59:C (2.6) BS01 DGT 2.7.4.6 GO:0004550 ... O64903 15465053
    4 1xjj:A (1.86) BS01 DGT 1.17.4.1 GO:0000166 ... O33839 15475969
    5 1xjj:A (1.86) BS02 DGT 1.17.4.1 GO:0000166 ... O33839 15475969
    6 1xjj:A (1.86) BS03 DGT 1.17.4.1 GO:0000166 ... O33839 15475969
    7 1xjj:B (1.86) BS01 DGT 1.17.4.1 GO:0000166 ... O33839 15475969
    8 1xjj:B (1.86) BS02 DGT 1.17.4.1 GO:0000166 ... O33839 15475969
    9 1xjj:B (1.86) BS03 DGT 1.17.4.1 GO:0000166 ... O33839 15475969
    10 1xjk:A (2.12) BS02 DGT 1.17.4.1 GO:0000166 ... O33839 15475969
    11 1xjk:A (2.12) BS03 DGT 1.17.4.1 GO:0000166 ... O33839 15475969
    12 1xjk:B (2.12) BS01 DGT 1.17.4.1 GO:0000166 ... O33839 15475969
    13 1xjk:B (2.12) BS03 DGT 1.17.4.1 GO:0000166 ... O33839 15475969
    14 1zjn:A (2.61) BS05 DGT 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 16084394
    15 2agp:A (2.9) BS06 DGT 2.7.7.7 GO:0000287 ... Q97W02 16107880
    16 2agp:B (2.9) BS07 DGT 2.7.7.7 GO:0000287 ... Q97W02 16107880
    17 2atz:A (2.0) BS01 DGT ? N/A O24984 N/A
    18 2bq1:E (3.99) BS01 DGT 1.17.4.1 GO:0004748 ... Q08698 16631785
    19 2bq1:E (3.99) BS02 DGT 1.17.4.1 GO:0004748 ... Q08698 16631785
    20 2bq1:F (3.99) BS01 DGT 1.17.4.1 GO:0004748 ... Q08698 16631785
    21 2c22:A (2.56) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 16306039
    22 2cvx:A (2.2) BS01 DGT 1.17.4.1 GO:0000166 ... P21524 16537479
    23 2e2i:B (3.41) BS04 DGT 2.7.7.6 GO:0000428 ... P08518 17129781
    24 2iry:A (1.78) BS02 DGT 6.5.1.1 N/A P9WNV3 17174332
    25 2iry:B (1.78) BS02 DGT 6.5.1.1 N/A P9WNV3 17174332
    26 2j6u:A (2.5) BS06 DGT 2.7.7.7 GO:0000287 ... Q97W02 17105728
    27 2jef:A (2.17) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 17337730
    28 2jeg:A (2.38) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 17337730
    29 2jei:A (2.39) BS06 DGT 2.7.7.7 GO:0000287 ... Q97W02 17337730
    30 2jej:A (1.86) BS06 DGT 2.7.7.7 GO:0000287 ... Q97W02 17337730
    31 2m2u:A (-1.00) BS01 DGT 2.7.7.7 GO:0003677 ... P42494 24617852
    32 2m2w:A (-1.00) BS02 DGT 2.7.7.7 GO:0003677 ... P42494 24617852
    33 2pyj:A (2.03) BS05 DGT 2.7.7.7
    3.1.11.-
    GO:0000166 ... P03680 17611604
    34 2pyj:B (2.03) BS08 DGT 2.7.7.7
    3.1.11.-
    GO:0000166 ... P03680 17611604
    35 2r8g:A (2.7) BS06 DGT 2.7.7.7 GO:0000287 ... Q97W02 18563918
    36 2r8h:A (2.48) BS06 DGT 2.7.7.7 GO:0000287 ... Q97W02 18563918
    37 2uvr:A (2.9) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 17468100
    38 2uvu:A (2.7) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 17468100
    39 2uvv:A (2.2) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 17468100
    40 2uvw:A (2.09) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 17468100
    41 2v4q:A (2.6) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 19492857
    42 2v4r:A (2.5) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 19492857
    43 2va3:A (2.98) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 17951245
    44 2vp2:A (2.5) BS01 DGT 2.7.1.145 GO:0004136 ... Q9XZT6 18384378
    45 2vp2:B (2.5) BS01 DGT 2.7.1.145 GO:0004136 ... Q9XZT6 18384378
    46 2w7o:A (3.16) BS03 DGT 2.7.7.7 GO:0003684 ... Q9UBT6 19542228
    47 2w7o:B (3.16) BS03 DGT 2.7.7.7 GO:0003684 ... Q9UBT6 19542228
    48 2w8k:A (3.1) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 19059910
    49 2w8l:A (3.0) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 19059910
    50 2w9a:A (2.6) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 19542237
    51 2xca:A (2.5) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 20823515
    52 3au2:A (1.4) BS01 DGT 2.7.7.7
    4.2.99.18
    GO:0003677 ... Q5SJ64 22306405
    53 3b0x:A (1.36) BS07 DGT 2.7.7.7
    4.2.99.18
    GO:0003677 ... Q5SJ64 22306405
    54 3b0y:A (1.45) BS01 DGT 2.7.7.7
    4.2.99.18
    GO:0003677 ... Q5SJ64 22306405
    55 3ef5:A (2.6) BS01 DGT 3.6.1.55 GO:0005525 ... Q6MPX4 19278661
    56 3ef5:B (2.6) BS01 DGT 3.6.1.55 GO:0005525 ... Q6MPX4 19278661
    57 3f2b:A (2.39) BS07 DGT 2.7.7.7 GO:0003676 ... Q5L0J3 19106298
    58 3f2c:A (2.5) BS07 DGT 2.7.7.7 GO:0003676 ... Q5L0J3 19106298
    59 3f2d:A (2.51) BS08 DGT 2.7.7.7 GO:0003676 ... Q5L0J3 19106298
    60 3g6x:A (2.08) BS03 DGT 2.7.7.7 GO:0003684 ... Q9UNA4 19368886
    61 3gii:A (2.6) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 19446528
    62 3gij:A (2.4) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 19446528
    63 3gij:B (2.4) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 19446528
    64 3gik:A (2.9) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 19446528
    65 3gil:A (2.71) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 19446528
    66 3gil:B (2.71) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 19446528
    67 3gim:A (2.7) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 19446528
    68 3gv8:B (2.0) BS04 DGT 2.7.7.7 GO:0003684 ... Q9UNA4 19440206
    69 3h4d:A (2.2) BS05 DGT 2.7.7.7 GO:0003684 ... Q9UNA4 19604477
    70 3irh:A (2.4) BS02 DGT ? GO:0000166 ... Q836G9 21757692
    71 3irh:A (2.4) BS03 DGT ? GO:0000166 ... Q836G9 21757692
    72 3irh:B (2.4) BS01 DGT ? GO:0000166 ... Q836G9 21757692
    73 3irh:B (2.4) BS02 DGT ? GO:0000166 ... Q836G9 21757692
    74 3irh:C (2.4) BS02 DGT ? GO:0000166 ... Q836G9 21757692
    75 3irh:C (2.4) BS03 DGT ? GO:0000166 ... Q836G9 21757692
    76 3irh:D (2.4) BS01 DGT ? GO:0000166 ... Q836G9 21757692
    77 3irh:D (2.4) BS02 DGT ? GO:0000166 ... Q836G9 21757692
    78 3k8t:A (2.1) BS01 DGT 1.17.4.1 GO:0000166 ... P21524 19681093
    79 3khg:A (2.96) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 20154704
    80 3khg:B (2.96) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 20154704
    81 3khh:A (2.7) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 20154704
    82 3khh:B (2.7) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 20154704
    83 3maq:A (2.4) BS03 DGT 2.7.7.7 GO:0000166 ... P21189 20064374
    84 3otb:A (2.95) BS01 DGT 2.7.7.79 GO:0000049 ... Q9NWX6 21059936
    85 3otb:B (2.95) BS02 DGT 2.7.7.79 GO:0000049 ... Q9NWX6 21059936
    86 3pkq:A (2.4) BS01 DGT 2.7.7.24 GO:0000287 ... P26393 21317292
    87 3pkq:B (2.4) BS01 DGT 2.7.7.24 GO:0000287 ... P26393 21317292
    88 3pkq:C (2.4) BS01 DGT 2.7.7.24 GO:0000287 ... P26393 21317292
    89 3pkq:D (2.4) BS01 DGT 2.7.7.24 GO:0000287 ... P26393 21317292
    90 3q8r:B (2.45) BS03 DGT 2.7.7.7 GO:0003684 ... Q9UNA4 21300901
    91 3qes:A (1.98) BS03 DGT 2.7.7.7
    3.1.11.-
    GO:0000166 ... Q38087 22304682
    92 3qex:A (1.73) BS03 DGT 2.7.7.7
    3.1.11.-
    GO:0000166 ... Q38087 N/A
    93 3qnn:A (1.92) BS03 DGT 2.7.7.7
    3.1.11.-
    GO:0000166 ... Q38087 22616982
    94 3raq:A (2.25) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 21645853
    95 3raq:B (2.25) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 21645853
    96 3rax:A (1.891) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 21645853
    97 3rax:B (1.891) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 21645853
    98 3rb0:A (3.225) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 21645853
    99 3rb0:B (3.225) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 21645853
    100 3rb3:A (2.8) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 21645853
    101 3rb4:A (2.805) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 21645853
    102 3rb4:B (2.805) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 21645853
    103 3rb6:A (2.7) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 21645853
    104 3rb6:B (2.7) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 21645853
    105 3rbd:A (2.502) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 21645853
    106 3rbd:B (2.502) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 21645853
    107 3rbe:A (2.8) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 21645853
    108 3rbe:B (2.8) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 21645853
    109 3s87:A (2.25) BS01 DGT 1.17.4.1 GO:0000166 ... P21524 N/A
    110 3s8a:A (2.9) BS01 DGT 1.17.4.1 GO:0000166 ... P21524 N/A
    111 3t5h:A (2.35) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 22313351
    112 3t5l:A (2.9) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 22313351
    113 3tba:A (2.8) BS01 DGT 1.17.4.1 GO:0000166 ... P21524 22465672
    114 4bzb:A (1.83) BS01 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    115 4bzb:A (1.83) BS02 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    116 4bzb:A (1.83) BS03 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    117 4bzb:A (1.83) BS04 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    118 4bzb:A (1.83) BS05 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    119 4bzb:A (1.83) BS06 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    120 4bzb:B (1.83) BS01 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    121 4bzb:B (1.83) BS02 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    122 4bzb:B (1.83) BS03 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    123 4bzb:B (1.83) BS04 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    124 4bzb:B (1.83) BS05 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    125 4bzb:B (1.83) BS06 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    126 4bzb:C (1.83) BS01 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    127 4bzb:C (1.83) BS02 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    128 4bzb:C (1.83) BS03 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    129 4bzb:C (1.83) BS04 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    130 4bzb:C (1.83) BS05 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    131 4bzb:C (1.83) BS06 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    132 4bzb:D (1.83) BS01 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    133 4bzb:D (1.83) BS02 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    134 4bzb:D (1.83) BS03 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    135 4bzb:D (1.83) BS04 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    136 4bzb:D (1.83) BS05 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    137 4bzb:D (1.83) BS06 DGT 3.1.5.- N/A Q9Y3Z3 24141705
    138 4dsj:A (2.86) BS03 DGT 2.7.7.7 GO:0000166 ... E1C9K5 N/A
    139 4dtp:A (2.05) BS03 DGT 2.7.7.7
    3.1.11.-
    GO:0000166 ... Q38087 22630605
    140 4dtu:A (1.86) BS03 DGT 2.7.7.7
    3.1.11.-
    GO:0000166 ... Q38087 22630605
    141 4fbt:A (2.0) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 23876706
    142 4fj7:A (1.9) BS03 DGT 2.7.7.7
    3.1.11.-
    GO:0000166 ... Q38087 23214497
    143 4fjh:A (2.11) BS03 DGT 2.7.7.7
    3.1.11.-
    GO:0000166 ... Q38087 23214497
    144 4fjl:A (1.87) BS03 DGT 2.7.7.7
    3.1.11.-
    GO:0000166 ... Q38087 23214497
    145 4fk4:A (1.9) BS03 DGT 2.7.7.7
    3.1.11.-
    GO:0000166 ... Q38087 23214497
    146 4fyd:A (3.1) BS04 DGT 2.7.7.7 GO:0000166 ... P13382 23599895
    147 4fyd:B (3.1) BS04 DGT 2.7.7.7 GO:0000166 ... P13382 23599895
    148 4juz:A (2.65) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 23947567
    149 4jv1:A (2.3) BS03 DGT 2.7.7.7 GO:0000287 ... Q97W02 23947567
    150 4lrl:A (2.35) BS01 DGT ? GO:0000166 ... Q836G9 24338016
    151 4lrl:A (2.35) BS02 DGT ? GO:0000166 ... Q836G9 24338016
    152 4lrl:B (2.35) BS01 DGT ? GO:0000166 ... Q836G9 24338016
    153 4lrl:B (2.35) BS02 DGT ? GO:0000166 ... Q836G9 24338016
    154 4lrl:C (2.35) BS01 DGT ? GO:0000166 ... Q836G9 24338016
    155 4lrl:C (2.35) BS02 DGT ? GO:0000166 ... Q836G9 24338016
    156 4lrl:D (2.35) BS02 DGT ? GO:0000166 ... Q836G9 24338016
    157 4lrl:D (2.35) BS03 DGT ? GO:0000166 ... Q836G9 24338016
    158 4mz7:A (1.8) BS02 DGT 3.1.5.- N/A Q9Y3Z3 24217394
    159 4mz7:A (1.8) BS03 DGT 3.1.5.- N/A Q9Y3Z3 24217394
    160 4mz7:A (1.8) BS04 DGT 3.1.5.- N/A Q9Y3Z3 24217394
    161 4mz7:A (1.8) BS05 DGT 3.1.5.- N/A Q9Y3Z3 24217394
    162 4mz7:B (1.8) BS01 DGT 3.1.5.- N/A Q9Y3Z3 24217394
    163 4mz7:B (1.8) BS02 DGT 3.1.5.- N/A Q9Y3Z3 24217394
    164 4mz7:B (1.8) BS03 DGT 3.1.5.- N/A Q9Y3Z3 24217394
    165 4mz7:B (1.8) BS05 DGT 3.1.5.- N/A Q9Y3Z3 24217394
    166 4qfx:A (2.2) BS01 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    167 4qfx:A (2.2) BS02 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    168 4qfx:A (2.2) BS04 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    169 4qfx:B (2.2) BS02 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    170 4qfx:B (2.2) BS03 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    171 4qfx:B (2.2) BS05 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    172 4qfx:C (2.2) BS02 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    173 4qfx:C (2.2) BS04 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    174 4qfx:C (2.2) BS05 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    175 4qfx:D (2.2) BS01 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    176 4qfx:D (2.2) BS02 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    177 4qfx:D (2.2) BS06 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    178 4qfy:A (2.1) BS01 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    179 4qfy:A (2.1) BS03 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    180 4qfy:A (2.1) BS04 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    181 4qfy:A (2.1) BS05 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    182 4qfy:A (2.1) BS06 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    183 4qfy:B (2.1) BS01 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    184 4qfy:B (2.1) BS03 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    185 4qfy:B (2.1) BS04 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    186 4qfy:B (2.1) BS05 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    187 4qfy:B (2.1) BS06 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    188 4qfy:C (2.1) BS01 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    189 4qfy:C (2.1) BS02 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    190 4qfy:C (2.1) BS03 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    191 4qfy:C (2.1) BS04 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    192 4qfy:C (2.1) BS06 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    193 4qfy:D (2.1) BS01 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    194 4qfy:D (2.1) BS02 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    195 4qfy:D (2.1) BS03 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    196 4qfy:D (2.1) BS04 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    197 4qfy:D (2.1) BS05 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    198 4qfz:A (2.3) BS01 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    199 4qfz:A (2.3) BS06 DGT 3.1.5.- N/A Q9Y3Z3 25288794
    200 4qfz:B (2.3) BS04 DGT 3.1.5.- N/A Q9Y3Z3 25288794

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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