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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
Download all results in tab-seperated text for 6639 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1001 2b7j:A (2.3) BS02 CU ? N/A P23833 16570183
    1002 2b7j:C (2.3) BS01 CU ? N/A P23833 16570183
    1003 2b7j:C (2.3) BS02 CU ? N/A P23833 16570183
    1004 2bp0:A (1.9) BS01 CU 1.7.2.1 GO:0005507 ... O68601 15927201
    1005 2bp0:A (1.9) BS02 CU 1.7.2.1 GO:0005507 ... O68601 15927201
    1006 2bp0:B (1.9) BS01 CU 1.7.2.1 GO:0005507 ... O68601 15927201
    1007 2bp0:B (1.9) BS02 CU 1.7.2.1 GO:0005507 ... O68601 15927201
    1008 2bp8:A (1.9) BS01 CU 1.7.2.1 GO:0005507 ... O68601 15927201
    1009 2bp8:A (1.9) BS02 CU 1.7.2.1 GO:0005507 ... O68601 15927201
    1010 2bp8:B (1.9) BS01 CU 1.7.2.1 GO:0005507 ... O68601 15927201
    1011 2bp8:B (1.9) BS02 CU 1.7.2.1 GO:0005507 ... O68601 15927201
    1012 2bt3:A (1.73) BS01 CU 1.4.3.21 GO:0005507 ... P46881 16157884
    1013 2bw4:A (0.9) BS01 CU 1.7.2.1 GO:0005507 ... P25006 16093314
    1014 2bw4:A (0.9) BS02 CU 1.7.2.1 GO:0005507 ... P25006 16093314
    1015 2bw5:A (1.12) BS01 CU 1.7.2.1 GO:0005507 ... P25006 16093314
    1016 2bw5:A (1.12) BS02 CU 1.7.2.1 GO:0005507 ... P25006 16093314
    1017 2bwd:A (1.15) BS01 CU 1.7.2.1 GO:0005507 ... P25006 16093314
    1018 2bwd:A (1.15) BS02 CU 1.7.2.1 GO:0005507 ... P25006 16093314
    1019 2bwi:A (1.1) BS01 CU 1.7.2.1 GO:0005507 ... P25006 16093314
    1020 2bwi:A (1.1) BS02 CU 1.7.2.1 GO:0005507 ... P25006 16093314
    1021 2bz7:A (1.76) BS01 CU ? GO:0005507 ... Q7SIB8 17367139
    1022 2c10:A (2.5) BS02 CU 1.4.3.21 GO:0005507 ... Q16853 16239734
    1023 2c10:B (2.5) BS02 CU 1.4.3.21 GO:0005507 ... Q16853 16239734
    1024 2c10:C (2.5) BS02 CU 1.4.3.21 GO:0005507 ... Q16853 16239734
    1025 2c10:D (2.5) BS02 CU 1.4.3.21 GO:0005507 ... Q16853 16239734
    1026 2c11:A (2.9) BS02 CU 1.4.3.21 GO:0005507 ... Q16853 16239734
    1027 2c11:A (2.9) BS04 CU 1.4.3.21 GO:0005507 ... Q16853 16239734
    1028 2c11:A (2.9) BS05 CU 1.4.3.21 GO:0005507 ... Q16853 16239734
    1029 2c11:B (2.9) BS02 CU 1.4.3.21 GO:0005507 ... Q16853 16239734
    1030 2c11:B (2.9) BS04 CU 1.4.3.21 GO:0005507 ... Q16853 16239734
    1031 2c11:B (2.9) BS05 CU 1.4.3.21 GO:0005507 ... Q16853 16239734
    1032 2c11:C (2.9) BS02 CU 1.4.3.21 GO:0005507 ... Q16853 16239734
    1033 2c11:C (2.9) BS04 CU 1.4.3.21 GO:0005507 ... Q16853 16239734
    1034 2c11:C (2.9) BS05 CU 1.4.3.21 GO:0005507 ... Q16853 16239734
    1035 2c11:D (2.9) BS02 CU 1.4.3.21 GO:0005507 ... Q16853 16239734
    1036 2c11:D (2.9) BS04 CU 1.4.3.21 GO:0005507 ... Q16853 16239734
    1037 2c11:D (2.9) BS05 CU 1.4.3.21 GO:0005507 ... Q16853 16239734
    1038 2c9p:A (2.25) BS01 CU ? GO:0005507 ... P12376 16637653
    1039 2c9p:A (2.25) BS02 CU ? GO:0005507 ... P12376 16637653
    1040 2c9p:A (2.25) BS03 CU ? GO:0005507 ... P12376 16637653
    1041 2c9p:B (2.25) BS01 CU ? GO:0005507 ... P12376 16637653
    1042 2c9p:B (2.25) BS02 CU ? GO:0005507 ... P12376 16637653
    1043 2c9p:B (2.25) BS03 CU ? GO:0005507 ... P12376 16637653
    1044 2c9p:C (2.25) BS01 CU ? GO:0005507 ... P12376 16637653
    1045 2c9p:C (2.25) BS02 CU ? GO:0005507 ... P12376 16637653
    1046 2c9q:A (1.6) BS01 CU ? GO:0005507 ... P12376 16637653
    1047 2c9q:A (1.6) BS02 CU ? GO:0005507 ... P12376 16637653
    1048 2c9u:A (1.24) BS01 CU 1.15.1.1 GO:0000302 ... P00441 16406071
    1049 2c9u:F (1.24) BS02 CU 1.15.1.1 GO:0000302 ... P00441 16406071
    1050 2c9v:A (1.07) BS01 CU 1.15.1.1 GO:0000302 ... P00441 16406071
    1051 2c9v:F (1.07) BS01 CU 1.15.1.1 GO:0000302 ... P00441 16406071
    1052 2cbp:A (1.8) BS01 CU ? GO:0009055 ... P00303 8876647
    1053 2cfd:A (1.6) BS01 CU 1.4.3.21 GO:0005507 ... P46881 18507382
    1054 2cfd:B (1.6) BS01 CU 1.4.3.21 GO:0005507 ... P46881 18507382
    1055 2cfg:A (1.55) BS01 CU 1.4.3.21 GO:0005507 ... P46881 18507382
    1056 2cfg:B (1.55) BS02 CU 1.4.3.21 GO:0005507 ... P46881 18507382
    1057 2cfk:A (1.8) BS01 CU 1.4.3.21 GO:0005507 ... P46881 18507382
    1058 2cfl:A (1.8) BS01 CU 1.4.3.21 GO:0005507 ... P46881 18507382
    1059 2cfw:A (1.74) BS01 CU 1.4.3.21 GO:0005507 ... P46881 18507382
    1060 2cg0:A (1.8) BS01 CU 1.4.3.21 GO:0005507 ... P46881 18507382
    1061 2cg1:A (1.67) BS01 CU 1.4.3.21 GO:0005507 ... P46881 18507382
    1062 2cj3:A (1.7) BS01 CU ? GO:0005507 ... P46444 N/A
    1063 2cj3:B (1.7) BS01 CU ? GO:0005507 ... P46444 N/A
    1064 2cwt:A (1.82) BS01 CU 1.4.3.21 GO:0005507 ... P46881 16566584
    1065 2cwt:B (1.82) BS01 CU 1.4.3.21 GO:0005507 ... P46881 16566584
    1066 2cwu:A (1.85) BS01 CU 1.4.3.21 GO:0005507 ... P46881 16566584
    1067 2cwu:B (1.85) BS01 CU 1.4.3.21 GO:0005507 ... P46881 16566584
    1068 2cwv:A (1.85) BS01 CU 1.4.3.21 GO:0005507 ... P46881 16566584
    1069 2cwv:B (1.85) BS01 CU 1.4.3.21 GO:0005507 ... P46881 16566584
    1070 2d1w:A (1.74) BS01 CU 1.4.3.21 GO:0005507 ... P46881 16487484
    1071 2d1w:B (1.74) BS01 CU 1.4.3.21 GO:0005507 ... P46881 16487484
    1072 2dv6:A (2.2) BS01 CU 1.7.2.1 GO:0005507 ... Q8KKH4 17360521
    1073 2dv6:A (2.2) BS02 CU 1.7.2.1 GO:0005507 ... Q8KKH4 17360521
    1074 2dv6:A (2.2) BS03 CU 1.7.2.1 GO:0005507 ... Q8KKH4 17360521
    1075 2dv6:B (2.2) BS01 CU 1.7.2.1 GO:0005507 ... Q8KKH4 17360521
    1076 2dv6:B (2.2) BS02 CU 1.7.2.1 GO:0005507 ... Q8KKH4 17360521
    1077 2dv6:B (2.2) BS03 CU 1.7.2.1 GO:0005507 ... Q8KKH4 17360521
    1078 2dv6:C (2.2) BS01 CU 1.7.2.1 GO:0005507 ... Q8KKH4 17360521
    1079 2dv6:C (2.2) BS02 CU 1.7.2.1 GO:0005507 ... Q8KKH4 17360521
    1080 2dv6:C (2.2) BS03 CU 1.7.2.1 GO:0005507 ... Q8KKH4 17360521
    1081 2dv6:D (2.2) BS01 CU 1.7.2.1 GO:0005507 ... Q8KKH4 17360521
    1082 2dv6:D (2.2) BS02 CU 1.7.2.1 GO:0005507 ... Q8KKH4 17360521
    1083 2dv6:D (2.2) BS03 CU 1.7.2.1 GO:0005507 ... Q8KKH4 17360521
    1084 2dv6:E (2.2) BS01 CU 1.7.2.1 GO:0005507 ... Q8KKH4 17360521
    1085 2dv6:E (2.2) BS02 CU 1.7.2.1 GO:0005507 ... Q8KKH4 17360521
    1086 2dv6:E (2.2) BS03 CU 1.7.2.1 GO:0005507 ... Q8KKH4 17360521
    1087 2dv6:F (2.2) BS01 CU 1.7.2.1 GO:0005507 ... Q8KKH4 17360521
    1088 2dv6:F (2.2) BS02 CU 1.7.2.1 GO:0005507 ... Q8KKH4 17360521
    1089 2dv6:F (2.2) BS03 CU 1.7.2.1 GO:0005507 ... Q8KKH4 17360521
    1090 2dws:A (1.85) BS01 CU 1.7.2.1 GO:0005507 ... Q53239 17148448
    1091 2dws:A (1.85) BS02 CU 1.7.2.1 GO:0005507 ... Q53239 17148448
    1092 2dwt:A (1.9) BS01 CU 1.7.2.1 GO:0005507 ... Q53239 17148448
    1093 2dwt:A (1.9) BS02 CU 1.7.2.1 GO:0005507 ... Q53239 17148448
    1094 2dy2:A (2.26) BS01 CU 1.7.2.1 GO:0005507 ... Q53239 17148448
    1095 2dyr:A (1.8) BS01 CU 7.1.1.9 GO:0004129 ... P00396 17332748
    1096 2dyr:N (1.8) BS02 CU 7.1.1.9 GO:0004129 ... P00396 17332748
    1097 2dys:A (2.2) BS01 CU 7.1.1.9 GO:0004129 ... P00396 17332748
    1098 2dys:N (2.2) BS02 CU 7.1.1.9 GO:0004129 ... P00396 17332748
    1099 2e2t:A (2.05) BS01 CU 1.4.3.21 GO:0005507 ... P46881 N/A
    1100 2e2u:A (1.68) BS01 CU 1.4.3.21 GO:0005507 ... P46881 N/A
    1101 2e2u:B (1.68) BS01 CU 1.4.3.21 GO:0005507 ... P46881 N/A
    1102 2e2v:A (1.8) BS01 CU 1.4.3.21 GO:0005507 ... P46881 N/A
    1103 2e2v:B (1.8) BS01 CU 1.4.3.21 GO:0005507 ... P46881 N/A
    1104 2e46:A (2.3) BS01 CU 1.15.1.1 GO:0004784 ... Q08J22 N/A
    1105 2e47:A (2.11) BS01 CU 1.15.1.1 GO:0004784 ... Q08J22 N/A
    1106 2e47:B (2.11) BS01 CU 1.15.1.1 GO:0004784 ... Q08J22 N/A
    1107 2e86:A (1.5) BS02 CU 1.7.2.1 GO:0005507 ... P38501 18358002
    1108 2e86:B (1.5) BS03 CU 1.7.2.1 GO:0005507 ... P38501 18358002
    1109 2e86:C (1.5) BS02 CU 1.7.2.1 GO:0005507 ... P38501 18358002
    1110 2eib:A (2.1) BS01 CU 1.1.3.9 GO:0005576 ... P0CS93 17385891
    1111 2eid:A (2.2) BS01 CU 1.1.3.9 GO:0005576 ... P0CS93 17385891
    1112 2eie:A (1.8) BS02 CU 1.1.3.9 GO:0005576 ... P0CS93 17385891
    1113 2eij:A (1.9) BS01 CU 7.1.1.9 GO:0004129 ... P00396 17470809
    1114 2eij:N (1.9) BS01 CU 7.1.1.9 GO:0004129 ... P00396 17470809
    1115 2eik:A (2.1) BS01 CU 7.1.1.9 GO:0004129 ... P00396 17470809
    1116 2eik:N (2.1) BS01 CU 7.1.1.9 GO:0004129 ... P00396 17470809
    1117 2eil:A (2.1) BS01 CU 7.1.1.9 GO:0004129 ... P00396 17470809
    1118 2eil:N (2.1) BS01 CU 7.1.1.9 GO:0004129 ... P00396 17470809
    1119 2eim:A (2.6) BS01 CU 7.1.1.9 GO:0004129 ... P00396 17470809
    1120 2eim:N (2.6) BS01 CU 7.1.1.9 GO:0004129 ... P00396 17470809
    1121 2ein:A (2.7) BS01 CU 7.1.1.9 GO:0004129 ... P00396 17470809
    1122 2ein:N (2.7) BS01 CU 7.1.1.9 GO:0004129 ... P00396 17470809
    1123 2eiq:A (1.9) BS01 CU ? GO:0005515 ... P0AA25 17727880
    1124 2eiq:B (1.9) BS01 CU ? GO:0005515 ... P0AA25 17727880
    1125 2eir:A (2.5) BS01 CU ? GO:0005515 ... P0AA25 17727880
    1126 2eir:B (2.5) BS01 CU ? GO:0005515 ... P0AA25 17727880
    1127 2eir:C (2.5) BS01 CU ? GO:0005515 ... P0AA25 17727880
    1128 2eir:D (2.5) BS01 CU ? GO:0005515 ... P0AA25 17727880
    1129 2fjs:A (1.85) BS02 CU 1.7.2.1 GO:0005507 ... P38501 17227014
    1130 2fjs:B (1.85) BS02 CU 1.7.2.1 GO:0005507 ... P38501 17227014
    1131 2fjs:C (1.85) BS02 CU 1.7.2.1 GO:0005507 ... P38501 17227014
    1132 2fk1:A (1.6) BS01 CU ? GO:0016020 ... P05067 17239395
    1133 2fk3:A (2.4) BS01 CU ? GO:0016020 ... P05067 17239395
    1134 2fk3:E (2.4) BS01 CU ? GO:0016020 ... P05067 17239395
    1135 2fk3:F (2.4) BS01 CU ? GO:0016020 ... P05067 17239395
    1136 2fk3:H (2.4) BS01 CU ? GO:0016020 ... P05067 17239395
    1137 2fnw:A (1.4) BS01 CU ? GO:0005507 ... P00282 16569013
    1138 2fnw:B (1.4) BS01 CU ? GO:0005507 ... P00282 16569013
    1139 2fos:A (1.1) BS02 CU 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 16506782
    1140 2fou:A (0.99) BS02 CU 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 16506782
    1141 2fov:A (1.15) BS02 CU 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 16506782
    1142 2fqd:A (2.4) BS01 CU 1.16.3.4 GO:0004322 ... P36649 17217912
    1143 2fqe:A (1.92) BS01 CU 1.16.3.4 GO:0004322 ... P36649 17217912
    1144 2fqe:A (1.92) BS02 CU 1.16.3.4 GO:0004322 ... P36649 17217912
    1145 2fqf:A (2.0) BS01 CU 1.16.3.4 GO:0004322 ... P36649 17217912
    1146 2fqf:A (2.0) BS02 CU 1.16.3.4 GO:0004322 ... P36649 17217912
    1147 2fqg:A (2.3) BS01 CU 1.16.3.4 GO:0004322 ... P36649 17217912
    1148 2fqg:A (2.3) BS02 CU 1.16.3.4 GO:0004322 ... P36649 17217912
    1149 2ft6:A (1.25) BS01 CU ? GO:0005507 ... P00282 16651527
    1150 2fta:A (1.61) BS01 CU ? GO:0005507 ... P00282 16651527
    1151 2fta:B (1.61) BS01 CU ? GO:0005507 ... P00282 16651527
    1152 2fta:C (1.61) BS01 CU ? GO:0005507 ... P00282 16651527
    1153 2fta:D (1.61) BS01 CU ? GO:0005507 ... P00282 16651527
    1154 2fu7:A (1.85) BS01 CU 3.5.2.6 GO:0008270 ... P52700 17999929
    1155 2fu7:A (1.85) BS02 CU 3.5.2.6 GO:0008270 ... P52700 17999929
    1156 2fu7:B (1.85) BS01 CU 3.5.2.6 GO:0008270 ... P52700 17999929
    1157 2fu7:B (1.85) BS02 CU 3.5.2.6 GO:0008270 ... P52700 17999929
    1158 2gb2:A (1.25) BS01 CU ? GO:0005507 ... P22364 16819827
    1159 2gc4:C (1.9) BS01 CU ? GO:0005507 ... P22364 N/A
    1160 2gc4:G (1.9) BS01 CU ? GO:0005507 ... P22364 N/A
    1161 2gc4:K (1.9) BS01 CU ? GO:0005507 ... P22364 N/A
    1162 2gc4:O (1.9) BS01 CU ? GO:0005507 ... P22364 N/A
    1163 2ghz:A (1.6) BS01 CU ? GO:0005507 ... P00282 16846224
    1164 2ghz:B (1.6) BS01 CU ? GO:0005507 ... P00282 16846224
    1165 2gim:A (1.6) BS01 CU ? GO:0005507 ... P0C178 16929103
    1166 2gim:C (1.6) BS01 CU ? GO:0005507 ... P0C178 16929103
    1167 2gsm:A (2.0) BS04 CU 7.1.1.9 GO:0004129 ... P33517 17050688
    1168 2gsm:B (2.0) BS03 CU 7.1.1.9 GO:0004129 ... Q03736 17050688
    1169 2gsm:B (2.0) BS04 CU 7.1.1.9 GO:0004129 ... Q03736 17050688
    1170 2gsm:C (2.0) BS03 CU 7.1.1.9 GO:0004129 ... P33517 17050688
    1171 2gsm:D (2.0) BS03 CU 7.1.1.9 GO:0004129 ... Q03736 17050688
    1172 2gsm:D (2.0) BS04 CU 7.1.1.9 GO:0004129 ... Q03736 17050688
    1173 2h3x:C (2.5) BS01 CU ? GO:0005507 ... P00281 17087503
    1174 2h3x:F (2.5) BS01 CU ? GO:0005507 ... P00281 17087503
    1175 2h47:C (2.6) BS01 CU ? GO:0005507 ... P00281 17087503
    1176 2h5u:A (1.9) BS02 CU 1.10.3.2 GO:0005507 ... D0VWU3 17012782
    1177 2h5u:A (1.9) BS03 CU 1.10.3.2 GO:0005507 ... D0VWU3 17012782
    1178 2h5u:A (1.9) BS04 CU 1.10.3.2 GO:0005507 ... D0VWU3 17012782
    1179 2h5u:A (1.9) BS05 CU 1.10.3.2 GO:0005507 ... D0VWU3 17012782
    1180 2hrg:A (1.58) BS03 CU 1.10.3.2 GO:0005507 ... Q9HDQ0 N/A
    1181 2hrg:A (1.58) BS04 CU 1.10.3.2 GO:0005507 ... Q9HDQ0 N/A
    1182 2hrg:A (1.58) BS05 CU 1.10.3.2 GO:0005507 ... Q9HDQ0 N/A
    1183 2hrg:A (1.58) BS06 CU 1.10.3.2 GO:0005507 ... Q9HDQ0 N/A
    1184 2hrh:A (2.6) BS01 CU 1.10.3.2 GO:0005507 ... Q9HDQ0 N/A
    1185 2hrh:A (2.6) BS02 CU 1.10.3.2 GO:0005507 ... Q9HDQ0 N/A
    1186 2hrh:A (2.6) BS03 CU 1.10.3.2 GO:0005507 ... Q9HDQ0 N/A
    1187 2hrh:A (2.6) BS04 CU 1.10.3.2 GO:0005507 ... Q9HDQ0 N/A
    1188 2hx7:A (1.55) BS01 CU ? GO:0005507 ... P00282 17227035
    1189 2hx7:B (1.55) BS01 CU ? GO:0005507 ... P00282 17227035
    1190 2hzh:A (2.6) BS01 CU 1.10.3.2 GO:0005507 ... Q8TG94 N/A
    1191 2hzh:A (2.6) BS02 CU 1.10.3.2 GO:0005507 ... Q8TG94 N/A
    1192 2hzh:A (2.6) BS03 CU 1.10.3.2 GO:0005507 ... Q8TG94 N/A
    1193 2hzh:A (2.6) BS04 CU 1.10.3.2 GO:0005507 ... Q8TG94 N/A
    1194 2i7o:A (1.5) BS01 CU ? GO:0005507 ... P00282 18583608
    1195 2i7s:A (1.35) BS01 CU ? GO:0005507 ... P00282 19639996
    1196 2i7s:B (1.35) BS02 CU ? GO:0005507 ... P00282 19639996
    1197 2i7s:C (1.35) BS01 CU ? GO:0005507 ... P00282 19639996
    1198 2i7s:D (1.35) BS01 CU ? GO:0005507 ... P00282 19639996
    1199 2iaa:C (1.95) BS01 CU ? GO:0005507 ... P00281 17087503
    1200 2idf:A (2.25) BS01 CU ? GO:0005507 ... P00282 N/A

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218