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BioLiP
Download all results in tab-seperated text for 8 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1c8k:A (1.76) BS02 CPB 2.4.1.1 GO:0000166 ... P00489 10924512 MOAD: ic50=1uM
    PDBbind: -logKd/Ki=6.00, IC50=1uM
    BindingDB: IC50=1200nM
    2 1e1y:A (2.23) BS01 CPB 2.4.1.1 GO:0000166 ... P00489 10924512 MOAD: ic50=2.5uM
    PDBbind: -logKd/Ki=5.60, IC50=2.5uM
    BindingDB: IC50=1200nM
    3 3blr:A (2.8) BS01 CPB 2.7.11.22
    2.7.11.23    		 GO:0004672 ... P50750 18566585 PDBbind: -logKd/Ki=8.19, Kd=6.4nM
    BindingDB: IC50=20nM, Kd=6.4nM, Ki=3.0nM
    4 3ebp:A (2.0) BS01 CPB 2.4.1.1 GO:0000166 ... P00489 23279842 PDBbind: -logKd/Ki=5.91, Ki=1.24uM
    BindingDB: IC50=1200nM
    5 4o71:A (1.36) BS01 CPB ? N/A O60885 24568369 MOAD: ic50=18uM
    PDBbind: -logKd/Ki=4.74, IC50=18uM
    6 4o71:A (1.36) BS02 CPB ? N/A O60885 24568369 MOAD: ic50=18uM
    PDBbind: -logKd/Ki=4.74, IC50=18uM
    7 4o71:B (1.36) BS01 CPB ? N/A O60885 24568369 MOAD: ic50=18uM
    8 4o71:B (1.36) BS02 CPB ? N/A O60885 24568369 MOAD: ic50=18uM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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