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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
Download all results in tab-seperated text for 459 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    201 4i02:A (1.75) BS02 CMP ? GO:0003677 ... P0ACJ8 24058293
    202 4i02:A (1.75) BS03 CMP ? GO:0003677 ... P0ACJ8 24058293
    203 4i02:B (1.75) BS01 CMP ? GO:0003677 ... P0ACJ8 24058293
    204 4i02:B (1.75) BS02 CMP ? GO:0003677 ... P0ACJ8 24058293
    205 4i02:C (1.75) BS01 CMP ? GO:0003677 ... P0ACJ8 24058293
    206 4i02:D (1.75) BS01 CMP ? GO:0003677 ... P0ACJ8 24058293
    207 4i02:D (1.75) BS02 CMP ? GO:0003677 ... P0ACJ8 24058293
    208 4i02:E (1.75) BS01 CMP ? GO:0003677 ... P0ACJ8 24058293
    209 4i02:F (1.75) BS01 CMP ? GO:0003677 ... P0ACJ8 24058293
    210 4i09:A (2.05) BS01 CMP ? GO:0003677 ... P0ACJ8 24058293
    211 4i09:B (2.05) BS01 CMP ? GO:0003677 ... P0ACJ8 24058293
    212 4i0a:A (2.2) BS01 CMP ? GO:0003677 ... P0ACJ8 24058293
    213 4i0a:A (2.2) BS02 CMP ? GO:0003677 ... P0ACJ8 24058293
    214 4i0a:B (2.2) BS01 CMP ? GO:0003677 ... P0ACJ8 24058293
    215 4i0a:B (2.2) BS02 CMP ? GO:0003677 ... P0ACJ8 24058293
    216 4i0b:A (1.5) BS01 CMP ? GO:0003677 ... P0ACJ8 24058293
    217 4i0b:A (1.5) BS02 CMP ? GO:0003677 ... P0ACJ8 24058293
    218 4i0b:B (1.5) BS01 CMP ? GO:0003677 ... P0ACJ8 24058293
    219 4mgi:E (2.8) BS01 CMP ? GO:0005085 ... Q9EQZ6 N/A
    220 4mgi:E (2.8) BS02 CMP ? GO:0005085 ... Q9EQZ6 N/A
    221 4mgk:E (2.7) BS01 CMP ? GO:0005085 ... Q9EQZ6 N/A
    222 4mx3:A (3.88) BS01 CMP ? GO:0001707 ... P00514 24316401
    223 4mx3:A (3.88) BS02 CMP ? GO:0001707 ... P00514 24316401
    224 4mx3:B (3.88) BS01 CMP ? GO:0001707 ... P00514 24316401
    225 4mx3:B (3.88) BS02 CMP ? GO:0001707 ... P00514 24316401
    226 4qx5:A (1.318) BS01 CMP 2.7.11.12 GO:0004692 ... Q13976 25271401
    227 5ahw:A (2.15) BS01 CMP ? GO:0000166 ... A0QYW6 25802331 MOAD: Kd=0.000000064M
    PDBbind: -logKd/Ki=5.17, Kd=6.82uM
    228 5ahw:B (2.15) BS01 CMP ? GO:0000166 ... A0QYW6 25802331 MOAD: Kd=0.000000064M
    229 5ahw:C (2.15) BS01 CMP ? GO:0000166 ... A0QYW6 25802331 MOAD: Kd=0.000000064M
    230 5ahw:D (2.15) BS01 CMP ? GO:0000166 ... A0QYW6 25802331 MOAD: Kd=0.000000064M
    231 5ahw:E (2.15) BS02 CMP ? GO:0000166 ... A0QYW6 25802331 MOAD: Kd=0.000000064M
    232 5ahw:F (2.15) BS01 CMP ? GO:0000166 ... A0QYW6 25802331 MOAD: Kd=0.000000064M
    233 5btx:A (2.1) BS01 CMP N/A N/A N/A 26294765 MOAD: Kd=280uM
    PDBbind: -logKd/Ki=3.55, Kd=280uM
    234 5btx:B (2.1) BS01 CMP N/A N/A N/A 26294765 MOAD: Kd=280uM
    235 5c6c:A (2.05) BS01 CMP 2.7.11.12 N/A Q13237 26769964 MOAD: Kd=418nM
    236 5c6c:B (2.05) BS01 CMP 2.7.11.12 N/A Q13237 26769964 MOAD: Kd=418nM
    237 5ciz:A (5.0098) BS03 CMP ? GO:0003677 ... P0ACJ8 N/A
    238 5j3u:A (1.8) BS01 CMP 2.7.11.12 GO:0001932 ... A0A0F7V8B2 N/A
    239 5j3u:A (1.8) BS02 CMP 2.7.11.12 GO:0001932 ... A0A0F7V8B2 N/A
    240 5jrh:A (1.644) BS02 CMP 6.2.1.1 GO:0003987 ... Q8ZKF6 27974467
    241 5jrh:B (1.644) BS02 CMP 6.2.1.1 GO:0003987 ... Q8ZKF6 27974467
    242 5k8s:A (1.15) BS01 CMP 2.7.11.11 N/A Q7KQK0 27738107 MOAD: Kd=6nM
    PDBbind: -logKd/Ki=8.22, Kd=6nM
    243 5k8s:B (1.15) BS01 CMP 2.7.11.11 N/A Q7KQK0 27738107 MOAD: Kd=6nM
    244 5kbf:A (2.0) BS01 CMP 2.7.11.11 GO:0001932 ... Q7KQK0 27738107 MOAD: Kd=1.2nM
    PDBbind: -logKd/Ki=8.92, Kd=1.2nM
    245 5kbf:A (2.0) BS02 CMP 2.7.11.11 GO:0001932 ... Q7KQK0 27738107 MOAD: Kd=1.2nM
    PDBbind: -logKd/Ki=8.92, Kd=1.2nM
    246 5kbf:B (2.0) BS01 CMP 2.7.11.11 GO:0001932 ... Q7KQK0 27738107 MOAD: Kd=1.2nM
    247 5kbf:B (2.0) BS02 CMP 2.7.11.11 GO:0001932 ... Q7KQK0 27738107 MOAD: Kd=1.2nM
    248 5kjx:A (1.9) BS01 CMP ? N/A P10644 28583991
    249 5kjy:A (2.0) BS01 CMP ? N/A P10644 28583991
    250 5o3q:A (1.75) BS01 CMP ? GO:0005886 ... P73954 29735650 MOAD: Kd=2.1uM
    PDBbind: -logKd/Ki=5.68, Kd=2.1uM
    251 5o3q:A (1.75) BS02 CMP ? GO:0005886 ... P73954 29735650 MOAD: Kd=2.1uM
    PDBbind: -logKd/Ki=5.68, Kd=2.1uM
    252 5o3q:B (1.75) BS01 CMP ? GO:0005886 ... P73954 29735650 MOAD: Kd=2.1uM
    253 5o3q:B (1.75) BS02 CMP ? GO:0005886 ... P73954 29735650 MOAD: Kd=2.1uM
    254 5o3q:C (1.75) BS01 CMP ? GO:0005886 ... P73954 29735650 PDBbind: -logKd/Ki=5.68, Kd=2.1uM
    255 5o3q:C (1.75) BS02 CMP ? GO:0005886 ... P73954 29735650 PDBbind: -logKd/Ki=5.68, Kd=2.1uM
    256 5u6p:A (3.51) BS01 CMP ? GO:0005216 ... O60741 28086084
    257 5u6p:B (3.51) BS01 CMP ? GO:0005216 ... O60741 28086084
    258 5u6p:C (3.51) BS01 CMP ? GO:0005216 ... O60741 28086084
    259 5u6p:D (3.51) BS01 CMP ? GO:0005216 ... O60741 28086084
    260 5w10:A (2.15) BS01 CMP ? N/A Q72MQ6 28601495 MOAD: Kd=0.24uM
    PDBbind: -logKd/Ki=6.62, Kd=0.24uM
    261 5w10:B (2.15) BS01 CMP ? N/A Q72MQ6 28601495 MOAD: Kd=0.24uM
    262 5w10:C (2.15) BS01 CMP ? N/A Q72MQ6 28601495 MOAD: Kd=0.24uM
    263 5w10:D (2.15) BS01 CMP ? N/A Q72MQ6 28601495 MOAD: Kd=0.24uM
    264 6b6h:G (3.9) BS03 CMP ? GO:0003677 ... P0ACJ8 29146813
    265 6b6h:H (3.9) BS03 CMP ? GO:0003677 ... P0ACJ8 29146813
    266 6cju:A (3.35) BS01 CMP ? GO:0005221 ... G0GA88 30028291
    267 6cju:B (3.35) BS02 CMP ? GO:0005221 ... G0GA88 30028291
    268 6cju:C (3.35) BS02 CMP ? GO:0005221 ... G0GA88 30028291
    269 6cju:D (3.35) BS02 CMP ? GO:0005221 ... G0GA88 30028291
    270 6dt4:A (1.8) BS01 CMP ? GO:0000166 ... A0A2U2GZI4 31744922
    271 6dt4:B (1.8) BS01 CMP ? GO:0000166 ... A0A2U2GZI4 31744922
    272 6ezu:A (2.04) BS02 CMP N/A GO:0004114 ... N/A N/A
    273 6gpo:A (1.48) BS01 CMP 3.6.4.10 GO:0005524 ... P07900 30248409
    274 6gpr:A (2.35) BS01 CMP 3.6.4.10 GO:0005524 ... P07900 30248409
    275 6gqu:A (1.72) BS01 CMP 3.6.4.10 GO:0005524 ... P07900 30248409
    276 6gyo:A (3.4) BS01 CMP ? GO:0005216 ... Q9Y3Q4 N/A
    277 6gyo:B (3.4) BS01 CMP ? GO:0005216 ... Q9Y3Q4 N/A
    278 6gyo:C (3.4) BS01 CMP ? GO:0005216 ... Q9Y3Q4 N/A
    279 6gyo:D (3.4) BS01 CMP ? GO:0005216 ... Q9Y3Q4 N/A
    280 6h4g:A (2.14352) BS01 CMP ? GO:0001932 ... Q385V6 38517938
    281 6h4g:B (2.14352) BS01 CMP ? GO:0001932 ... Q385V6 38517938
    282 6h7e:A (2.3) BS01 CMP ? GO:0035556 ... O95398 37438343 BindingDB: Kd=4500nM
    283 6h7e:B (2.3) BS01 CMP ? GO:0035556 ... O95398 37438343 BindingDB: Kd=4500nM
    284 6hq3:A (2.79) BS01 CMP ? N/A Q6MLN6 31355487 PDBbind: -logKd/Ki=6.11, Kd=0.775uM
    285 6hq3:B (2.79) BS01 CMP ? N/A Q6MLN6 31355487
    286 6hq3:C (2.79) BS01 CMP ? N/A Q6MLN6 31355487
    287 6hq3:D (2.79) BS01 CMP ? N/A Q6MLN6 31355487 PDBbind: -logKd/Ki=6.11, Kd=0.775uM
    288 6hq4:A (2.63) BS01 CMP ? GO:0000166 ... Q6MLN6 31355487 PDBbind: -logKd/Ki=4.65, Kd=22.4uM
    289 6hq4:B (2.63) BS01 CMP ? GO:0000166 ... Q6MLN6 31355487 PDBbind: -logKd/Ki=4.65, Kd=22.4uM
    290 6hq5:A (2.83) BS02 CMP ? GO:0000166 ... Q6MLN6 31355487
    291 6hq5:B (2.83) BS01 CMP ? GO:0000166 ... Q6MLN6 31355487
    292 6hq5:B (2.83) BS03 CMP ? GO:0000166 ... Q6MLN6 31355487
    293 6loq:A (1.331) BS01 CMP 3.2.2.22 GO:0017148 ... P16094 32653369
    294 6m63:A (2.25) BS01 CMP ? GO:0005221 ... P42212
    Q98GN8
    36097007
    295 6m63:B (2.25) BS01 CMP ? GO:0005221 ... P42212
    Q98GN8
    36097007
    296 6mmq:A (2.02) BS01 CMP ? GO:0005524 ... B5II98 N/A PDBbind: -logKd/Ki=3.62, Kd=238uM
    297 6mmq:A (2.02) BS02 CMP ? GO:0005524 ... B5II98 N/A PDBbind: -logKd/Ki=3.62, Kd=238uM
    298 6mmq:B (2.02) BS01 CMP ? GO:0005524 ... B5II98 N/A
    299 6mmq:B (2.02) BS02 CMP ? GO:0005524 ... B5II98 N/A
    300 6mmq:C (2.02) BS01 CMP ? GO:0005524 ... B5II98 N/A
    301 6mmq:C (2.02) BS02 CMP ? GO:0005524 ... B5II98 N/A
    302 6mmq:D (2.02) BS01 CMP ? GO:0005524 ... B5II98 N/A PDBbind: -logKd/Ki=3.62, Kd=238uM
    303 6mmq:D (2.02) BS02 CMP ? GO:0005524 ... B5II98 N/A PDBbind: -logKd/Ki=3.62, Kd=238uM
    304 6mmq:E (2.02) BS01 CMP ? GO:0005524 ... B5II98 N/A
    305 6mmq:E (2.02) BS02 CMP ? GO:0005524 ... B5II98 N/A
    306 6mmq:F (2.02) BS01 CMP ? GO:0005524 ... B5II98 N/A
    307 6mmq:F (2.02) BS02 CMP ? GO:0005524 ... B5II98 N/A
    308 6pb4:G (4.35) BS03 CMP ? GO:0003677 ... P0ACJ8 N/A
    309 6pb4:H (4.35) BS02 CMP ? GO:0003677 ... P0ACJ8 N/A
    310 6pb5:G (4.52) BS03 CMP ? GO:0003677 ... P0ACJ8 N/A
    311 6pb5:H (4.52) BS03 CMP ? GO:0003677 ... P0ACJ8 N/A
    312 6pb6:G (4.29) BS02 CMP ? GO:0003677 ... P0ACJ8 N/A
    313 6pb6:H (4.29) BS02 CMP ? GO:0003677 ... P0ACJ8 N/A
    314 6rsx:A (1.6) BS01 CMP N/A GO:0001932 ... N/A N/A
    315 6rsx:A (1.6) BS02 CMP N/A GO:0001932 ... N/A N/A
    316 6uqf:A (3.04) BS01 CMP ? GO:0005216 ... O60741 31787376
    317 6uqf:B (3.04) BS01 CMP ? GO:0005216 ... O60741 31787376
    318 6uqf:C (3.04) BS01 CMP ? GO:0005216 ... O60741 31787376
    319 6uqf:D (3.04) BS01 CMP ? GO:0005216 ... O60741 31787376
    320 6uqg:A (3.54) BS01 CMP ? GO:0005216 ... O60741 31787376
    321 6uqg:B (3.54) BS01 CMP ? GO:0005216 ... O60741 31787376
    322 6uqg:C (3.54) BS01 CMP ? GO:0005216 ... O60741 31787376
    323 6uqg:D (3.54) BS01 CMP ? GO:0005216 ... O60741 31787376
    324 6vxz:A (3.42) BS01 CMP ? GO:0005221 ... G0GA88 33328472
    325 6vxz:B (3.42) BS01 CMP ? GO:0005221 ... G0GA88 33328472
    326 6vxz:C (3.42) BS01 CMP ? GO:0005221 ... G0GA88 33328472
    327 6vxz:D (3.42) BS01 CMP ? GO:0005221 ... G0GA88 33328472
    328 7e3w:A (1.55) BS01 CMP ? GO:0016787 ... Q2FXM0 33950015
    329 7e3w:B (1.55) BS01 CMP ? GO:0016787 ... Q2FXM0 33950015
    330 7e3w:C (1.55) BS01 CMP ? GO:0016787 ... Q2FXM0 33950015
    331 7e3w:D (1.55) BS01 CMP ? GO:0016787 ... Q2FXM0 33950015
    332 7e3w:E (1.55) BS01 CMP ? GO:0016787 ... Q2FXM0 33950015
    333 7e3w:F (1.55) BS01 CMP ? GO:0016787 ... Q2FXM0 33950015
    334 7few:A (1.75) BS01 CMP ? GO:0000976 ... P55222 37007650
    335 7few:B (1.75) BS01 CMP ? GO:0000976 ... P55222 37007650
    336 7ff0:A (2.6) BS01 CMP ? GO:0000976 ... P55222 37007650
    337 7ff0:B (2.6) BS01 CMP ? GO:0000976 ... P55222 37007650
    338 7ff8:A (2.8) BS01 CMP ? GO:0000976 ... P55222 N/A
    339 7ff8:B (2.8) BS01 CMP ? GO:0000976 ... P55222 N/A
    340 7ff9:A (2.4) BS01 CMP ? GO:0000976 ... P55222 N/A
    341 7ff9:B (2.4) BS01 CMP ? GO:0000976 ... P55222 N/A
    342 7ff9:C (2.4) BS01 CMP ? GO:0000976 ... P55222 N/A
    343 7ff9:D (2.4) BS01 CMP ? GO:0000976 ... P55222 N/A
    344 7ff9:E (2.4) BS01 CMP ? GO:0000976 ... P55222 N/A
    345 7ff9:F (2.4) BS01 CMP ? GO:0000976 ... P55222 N/A
    346 7ff9:G (2.4) BS01 CMP ? GO:0000976 ... P55222 N/A
    347 7ff9:H (2.4) BS01 CMP ? GO:0000976 ... P55222 N/A
    348 7jme:A (1.55) BS01 CMP 2.1.1.56
    2.1.1.57
    2.7.7.48
    2.7.7.50
    3.1.13.-
    3.4.19.12
    3.4.22.-
    3.4.22.69
    3.6.4.12
    3.6.4.13
    4.6.1.-
    N/A P0DTD1 32981460
    349 7lz4:A (4.155) BS01 CMP ? GO:0001932 ... P00514 34006641
    350 7lz4:A (4.155) BS02 CMP ? GO:0001932 ... P00514 34006641
    351 7lz4:B (4.155) BS01 CMP ? GO:0001932 ... P00514 34006641
    352 7lz4:B (4.155) BS02 CMP ? GO:0001932 ... P00514 34006641
    353 7lz4:C (4.155) BS01 CMP ? GO:0001932 ... P00514 34006641
    354 7lz4:C (4.155) BS02 CMP ? GO:0001932 ... P00514 34006641
    355 7lz4:D (4.155) BS01 CMP ? GO:0001932 ... P00514 34006641
    356 7lz4:D (4.155) BS02 CMP ? GO:0001932 ... P00514 34006641
    357 7lz4:E (4.155) BS01 CMP ? GO:0001932 ... P00514 34006641
    358 7lz4:E (4.155) BS02 CMP ? GO:0001932 ... P00514 34006641
    359 7lz4:F (4.155) BS01 CMP ? GO:0001932 ... P00514 34006641
    360 7lz4:F (4.155) BS02 CMP ? GO:0001932 ... P00514 34006641
    361 7lz4:G (4.155) BS01 CMP ? GO:0001932 ... P00514 34006641
    362 7lz4:G (4.155) BS02 CMP ? GO:0001932 ... P00514 34006641
    363 7lz4:H (4.155) BS01 CMP ? GO:0001932 ... P00514 34006641
    364 7lz4:H (4.155) BS02 CMP ? GO:0001932 ... P00514 34006641
    365 7np4:A (3.3) BS01 CMP ? GO:0005216 ... Q9TV66 34166608
    366 7np4:B (3.3) BS01 CMP ? GO:0005216 ... Q9TV66 34166608
    367 7np4:C (3.3) BS01 CMP ? GO:0005216 ... Q9TV66 34166608
    368 7np4:D (3.3) BS01 CMP ? GO:0005216 ... Q9TV66 34166608
    369 7pza:A (2.72) BS03 CMP ? GO:0000166 ... Q92SD2 37017526
    370 7pza:B (2.72) BS03 CMP ? GO:0000166 ... Q92SD2 37017526
    371 7rhg:A (2.88) BS01 CMP ? GO:0005216 ... P29973 34699778
    372 7rhg:B (2.88) BS01 CMP ? GO:0005221 ... Q14028 34699778
    373 7rhg:C (2.88) BS01 CMP ? GO:0005216 ... P29973 34699778
    374 7rhg:D (2.88) BS01 CMP ? GO:0005216 ... P29973 34699778
    375 7rsh:A (3.0) BS01 CMP ? GO:0005221 ... G0GA88 36376326
    376 7rsh:B (3.0) BS01 CMP ? GO:0005221 ... G0GA88 36376326
    377 7rsh:C (3.0) BS01 CMP ? GO:0005221 ... G0GA88 36376326
    378 7rsh:D (3.0) BS01 CMP ? GO:0005221 ... G0GA88 36376326
    379 7rtf:A (2.9) BS01 CMP ? GO:0005221 ... G0GA88 36376326
    380 7rtf:B (2.9) BS01 CMP ? GO:0005221 ... G0GA88 36376326
    381 7rtf:C (2.9) BS01 CMP ? GO:0005221 ... G0GA88 36376326
    382 7rtf:D (2.9) BS01 CMP ? GO:0005221 ... G0GA88 36376326
    383 7rtj:A (3.8) BS01 CMP ? GO:0005221 ... G0GA88 36376326
    384 7rtj:B (3.8) BS02 CMP ? GO:0005221 ... G0GA88 36376326
    385 7rtj:C (3.8) BS02 CMP ? GO:0005221 ... G0GA88 36376326
    386 7rtj:D (3.8) BS02 CMP ? GO:0005221 ... G0GA88 36376326
    387 7ru0:A (4.3) BS01 CMP ? GO:0005221 ... G0GA88 36376326
    388 7ru0:B (4.3) BS01 CMP ? GO:0005221 ... G0GA88 36376326
    389 7ru0:C (4.3) BS01 CMP ? GO:0005221 ... G0GA88 36376326
    390 7ru0:D (4.3) BS01 CMP ? GO:0005221 ... G0GA88 36376326
    391 7ryr:A (3.6) BS01 CMP ? GO:0005221 ... G0GA88 36376326
    392 7ryr:B (3.6) BS01 CMP ? GO:0005221 ... G0GA88 36376326
    393 7ryr:C (3.6) BS01 CMP ? GO:0005221 ... G0GA88 36376326
    394 7ryr:D (3.6) BS02 CMP ? GO:0005221 ... G0GA88 36376326
    395 7rys:A (3.7) BS01 CMP ? GO:0005221 ... G0GA88 36376326
    396 7rys:B (3.7) BS01 CMP ? GO:0005221 ... G0GA88 36376326
    397 7rys:C (3.7) BS01 CMP ? GO:0005221 ... G0GA88 36376326
    398 7rys:D (3.7) BS03 CMP ? GO:0005221 ... G0GA88 36376326
    399 7tj5:A (2.41) BS01 CMP ? GO:0005221 ... G0GA88 36352139
    400 7tj5:B (2.41) BS01 CMP ? GO:0005221 ... G0GA88 36352139

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218