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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
Download all results in tab-seperated text for 49284 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    4601 4y28:L (2.8) BS03 CLA ? GO:0009522 ... E1C9L1 26076232
    4602 4y28:L (2.8) BS04 CLA ? GO:0009522 ... E1C9L1 26076232
    4603 4y28:L (2.8) BS05 CLA ? GO:0009522 ... E1C9L1 26076232
    4604 4y28:L (2.8) BS06 CLA ? GO:0009522 ... E1C9L1 26076232
    4605 4y28:L (2.8) BS07 CLA ? GO:0009522 ... E1C9L1 26076232
    4606 4y28:L (2.8) BS08 CLA ? GO:0009522 ... E1C9L1 26076232
    4607 4y28:L (2.8) BS09 CLA ? GO:0009522 ... E1C9L1 26076232
    4608 4yuu:A1 (2.77) BS03 CLA 1.10.3.9 GO:0005506 ... O19895 26757821
    4609 4yuu:A1 (2.77) BS04 CLA 1.10.3.9 GO:0005506 ... O19895 26757821
    4610 4yuu:A1 (2.77) BS05 CLA 1.10.3.9 GO:0005506 ... O19895 26757821
    4611 4yuu:A1 (2.77) BS06 CLA 1.10.3.9 GO:0005506 ... O19895 26757821
    4612 4yuu:A1 (2.77) BS10 CLA 1.10.3.9 GO:0005506 ... O19895 26757821
    4613 4yuu:A2 (2.77) BS01 CLA 1.10.3.9 GO:0005506 ... O19895 26757821
    4614 4yuu:A2 (2.77) BS02 CLA 1.10.3.9 GO:0005506 ... O19895 26757821
    4615 4yuu:A2 (2.77) BS03 CLA 1.10.3.9 GO:0005506 ... O19895 26757821
    4616 4yuu:A2 (2.77) BS08 CLA 1.10.3.9 GO:0005506 ... O19895 26757821
    4617 4yuu:A2 (2.77) BS09 CLA 1.10.3.9 GO:0005506 ... O19895 26757821
    4618 4yuu:B1 (2.77) BS01 CLA ? GO:0009507 ... O19928 26757821
    4619 4yuu:B1 (2.77) BS02 CLA ? GO:0009507 ... O19928 26757821
    4620 4yuu:B1 (2.77) BS03 CLA ? GO:0009507 ... O19928 26757821
    4621 4yuu:B1 (2.77) BS04 CLA ? GO:0009507 ... O19928 26757821
    4622 4yuu:B1 (2.77) BS05 CLA ? GO:0009507 ... O19928 26757821
    4623 4yuu:B1 (2.77) BS06 CLA ? GO:0009507 ... O19928 26757821
    4624 4yuu:B1 (2.77) BS07 CLA ? GO:0009507 ... O19928 26757821
    4625 4yuu:B1 (2.77) BS08 CLA ? GO:0009507 ... O19928 26757821
    4626 4yuu:B1 (2.77) BS09 CLA ? GO:0009507 ... O19928 26757821
    4627 4yuu:B1 (2.77) BS10 CLA ? GO:0009507 ... O19928 26757821
    4628 4yuu:B1 (2.77) BS11 CLA ? GO:0009507 ... O19928 26757821
    4629 4yuu:B1 (2.77) BS12 CLA ? GO:0009507 ... O19928 26757821
    4630 4yuu:B1 (2.77) BS13 CLA ? GO:0009507 ... O19928 26757821
    4631 4yuu:B1 (2.77) BS14 CLA ? GO:0009507 ... O19928 26757821
    4632 4yuu:B1 (2.77) BS15 CLA ? GO:0009507 ... O19928 26757821
    4633 4yuu:B1 (2.77) BS16 CLA ? GO:0009507 ... O19928 26757821
    4634 4yuu:B2 (2.77) BS01 CLA ? GO:0009507 ... O19928 26757821
    4635 4yuu:B2 (2.77) BS02 CLA ? GO:0009507 ... O19928 26757821
    4636 4yuu:B2 (2.77) BS03 CLA ? GO:0009507 ... O19928 26757821
    4637 4yuu:B2 (2.77) BS04 CLA ? GO:0009507 ... O19928 26757821
    4638 4yuu:B2 (2.77) BS05 CLA ? GO:0009507 ... O19928 26757821
    4639 4yuu:B2 (2.77) BS06 CLA ? GO:0009507 ... O19928 26757821
    4640 4yuu:B2 (2.77) BS07 CLA ? GO:0009507 ... O19928 26757821
    4641 4yuu:B2 (2.77) BS08 CLA ? GO:0009507 ... O19928 26757821
    4642 4yuu:B2 (2.77) BS09 CLA ? GO:0009507 ... O19928 26757821
    4643 4yuu:B2 (2.77) BS10 CLA ? GO:0009507 ... O19928 26757821
    4644 4yuu:B2 (2.77) BS11 CLA ? GO:0009507 ... O19928 26757821
    4645 4yuu:B2 (2.77) BS12 CLA ? GO:0009507 ... O19928 26757821
    4646 4yuu:B2 (2.77) BS13 CLA ? GO:0009507 ... O19928 26757821
    4647 4yuu:B2 (2.77) BS14 CLA ? GO:0009507 ... O19928 26757821
    4648 4yuu:B2 (2.77) BS15 CLA ? GO:0009507 ... O19928 26757821
    4649 4yuu:B2 (2.77) BS16 CLA ? GO:0009507 ... O19928 26757821
    4650 4yuu:C1 (2.77) BS02 CLA ? GO:0005737 ... Q9TM46 26757821
    4651 4yuu:C1 (2.77) BS03 CLA ? GO:0005737 ... Q9TM46 26757821
    4652 4yuu:C1 (2.77) BS04 CLA ? GO:0005737 ... Q9TM46 26757821
    4653 4yuu:C1 (2.77) BS05 CLA ? GO:0005737 ... Q9TM46 26757821
    4654 4yuu:C1 (2.77) BS06 CLA ? GO:0005737 ... Q9TM46 26757821
    4655 4yuu:C1 (2.77) BS07 CLA ? GO:0005737 ... Q9TM46 26757821
    4656 4yuu:C1 (2.77) BS08 CLA ? GO:0005737 ... Q9TM46 26757821
    4657 4yuu:C1 (2.77) BS09 CLA ? GO:0005737 ... Q9TM46 26757821
    4658 4yuu:C1 (2.77) BS10 CLA ? GO:0005737 ... Q9TM46 26757821
    4659 4yuu:C1 (2.77) BS11 CLA ? GO:0005737 ... Q9TM46 26757821
    4660 4yuu:C1 (2.77) BS12 CLA ? GO:0005737 ... Q9TM46 26757821
    4661 4yuu:C1 (2.77) BS13 CLA ? GO:0005737 ... Q9TM46 26757821
    4662 4yuu:C1 (2.77) BS14 CLA ? GO:0005737 ... Q9TM46 26757821
    4663 4yuu:C2 (2.77) BS02 CLA ? GO:0005737 ... Q9TM46 26757821
    4664 4yuu:C2 (2.77) BS03 CLA ? GO:0005737 ... Q9TM46 26757821
    4665 4yuu:C2 (2.77) BS04 CLA ? GO:0005737 ... Q9TM46 26757821
    4666 4yuu:C2 (2.77) BS05 CLA ? GO:0005737 ... Q9TM46 26757821
    4667 4yuu:C2 (2.77) BS06 CLA ? GO:0005737 ... Q9TM46 26757821
    4668 4yuu:C2 (2.77) BS07 CLA ? GO:0005737 ... Q9TM46 26757821
    4669 4yuu:C2 (2.77) BS08 CLA ? GO:0005737 ... Q9TM46 26757821
    4670 4yuu:C2 (2.77) BS09 CLA ? GO:0005737 ... Q9TM46 26757821
    4671 4yuu:C2 (2.77) BS10 CLA ? GO:0005737 ... Q9TM46 26757821
    4672 4yuu:C2 (2.77) BS11 CLA ? GO:0005737 ... Q9TM46 26757821
    4673 4yuu:C2 (2.77) BS12 CLA ? GO:0005737 ... Q9TM46 26757821
    4674 4yuu:C2 (2.77) BS13 CLA ? GO:0005737 ... Q9TM46 26757821
    4675 4yuu:C2 (2.77) BS14 CLA ? GO:0005737 ... Q9TM46 26757821
    4676 4yuu:D1 (2.77) BS03 CLA 1.10.3.9 GO:0005506 ... Q9TM47 26757821
    4677 4yuu:D1 (2.77) BS04 CLA 1.10.3.9 GO:0005506 ... Q9TM47 26757821
    4678 4yuu:D1 (2.77) BS08 CLA 1.10.3.9 GO:0005506 ... Q9TM47 26757821
    4679 4yuu:D1 (2.77) BS09 CLA 1.10.3.9 GO:0005506 ... Q9TM47 26757821
    4680 4yuu:D1 (2.77) BS10 CLA 1.10.3.9 GO:0005506 ... Q9TM47 26757821
    4681 4yuu:D2 (2.77) BS01 CLA 1.10.3.9 GO:0005506 ... Q9TM47 26757821
    4682 4yuu:D2 (2.77) BS05 CLA 1.10.3.9 GO:0005506 ... Q9TM47 26757821
    4683 4yuu:D2 (2.77) BS06 CLA 1.10.3.9 GO:0005506 ... Q9TM47 26757821
    4684 4yuu:D2 (2.77) BS07 CLA 1.10.3.9 GO:0005506 ... Q9TM47 26757821
    4685 4yuu:D2 (2.77) BS08 CLA 1.10.3.9 GO:0005506 ... Q9TM47 26757821
    4686 4yuu:H1 (2.77) BS03 CLA ? GO:0009507 ... O19925 26757821
    4687 4yuu:H1 (2.77) BS04 CLA ? GO:0009507 ... O19925 26757821
    4688 4yuu:H1 (2.77) BS05 CLA ? GO:0009507 ... O19925 26757821
    4689 4yuu:H2 (2.77) BS02 CLA ? GO:0009507 ... O19925 26757821
    4690 4yuu:H2 (2.77) BS03 CLA ? GO:0009507 ... O19925 26757821
    4691 4yuu:I1 (2.77) BS02 CLA ? GO:0005737 ... O19882 26757821
    4692 4yuu:I2 (2.77) BS01 CLA ? GO:0005737 ... O19882 26757821
    4693 4yuu:K1 (2.77) BS02 CLA ? GO:0005737 ... Q9TLR0 26757821
    4694 4yuu:K1 (2.77) BS03 CLA ? GO:0005737 ... Q9TLR0 26757821
    4695 4yuu:K2 (2.77) BS02 CLA ? GO:0005737 ... Q9TLR0 26757821
    4696 4yuu:L2 (2.77) BS01 CLA ? GO:0005737 ... Q9TM22 26757821
    4697 4yuu:M2 (2.77) BS01 CLA N/A GO:0009523 ... N/A 26757821
    4698 4yuu:a1 (2.77) BS02 CLA 1.10.3.9 GO:0005506 ... O19895 26757821
    4699 4yuu:a1 (2.77) BS03 CLA 1.10.3.9 GO:0005506 ... O19895 26757821
    4700 4yuu:a1 (2.77) BS04 CLA 1.10.3.9 GO:0005506 ... O19895 26757821
    4701 4yuu:a1 (2.77) BS08 CLA 1.10.3.9 GO:0005506 ... O19895 26757821
    4702 4yuu:a1 (2.77) BS10 CLA 1.10.3.9 GO:0005506 ... O19895 26757821
    4703 4yuu:a2 (2.77) BS02 CLA 1.10.3.9 GO:0005506 ... O19895 26757821
    4704 4yuu:a2 (2.77) BS03 CLA 1.10.3.9 GO:0005506 ... O19895 26757821
    4705 4yuu:a2 (2.77) BS05 CLA 1.10.3.9 GO:0005506 ... O19895 26757821
    4706 4yuu:a2 (2.77) BS09 CLA 1.10.3.9 GO:0005506 ... O19895 26757821
    4707 4yuu:a2 (2.77) BS10 CLA 1.10.3.9 GO:0005506 ... O19895 26757821
    4708 4yuu:b1 (2.77) BS01 CLA ? GO:0009507 ... O19928 26757821
    4709 4yuu:b1 (2.77) BS02 CLA ? GO:0009507 ... O19928 26757821
    4710 4yuu:b1 (2.77) BS03 CLA ? GO:0009507 ... O19928 26757821
    4711 4yuu:b1 (2.77) BS04 CLA ? GO:0009507 ... O19928 26757821
    4712 4yuu:b1 (2.77) BS05 CLA ? GO:0009507 ... O19928 26757821
    4713 4yuu:b1 (2.77) BS06 CLA ? GO:0009507 ... O19928 26757821
    4714 4yuu:b1 (2.77) BS07 CLA ? GO:0009507 ... O19928 26757821
    4715 4yuu:b1 (2.77) BS08 CLA ? GO:0009507 ... O19928 26757821
    4716 4yuu:b1 (2.77) BS09 CLA ? GO:0009507 ... O19928 26757821
    4717 4yuu:b1 (2.77) BS10 CLA ? GO:0009507 ... O19928 26757821
    4718 4yuu:b1 (2.77) BS11 CLA ? GO:0009507 ... O19928 26757821
    4719 4yuu:b1 (2.77) BS12 CLA ? GO:0009507 ... O19928 26757821
    4720 4yuu:b1 (2.77) BS13 CLA ? GO:0009507 ... O19928 26757821
    4721 4yuu:b1 (2.77) BS14 CLA ? GO:0009507 ... O19928 26757821
    4722 4yuu:b1 (2.77) BS15 CLA ? GO:0009507 ... O19928 26757821
    4723 4yuu:b1 (2.77) BS16 CLA ? GO:0009507 ... O19928 26757821
    4724 4yuu:b2 (2.77) BS01 CLA ? GO:0009507 ... O19928 26757821
    4725 4yuu:b2 (2.77) BS02 CLA ? GO:0009507 ... O19928 26757821
    4726 4yuu:b2 (2.77) BS03 CLA ? GO:0009507 ... O19928 26757821
    4727 4yuu:b2 (2.77) BS04 CLA ? GO:0009507 ... O19928 26757821
    4728 4yuu:b2 (2.77) BS05 CLA ? GO:0009507 ... O19928 26757821
    4729 4yuu:b2 (2.77) BS06 CLA ? GO:0009507 ... O19928 26757821
    4730 4yuu:b2 (2.77) BS07 CLA ? GO:0009507 ... O19928 26757821
    4731 4yuu:b2 (2.77) BS08 CLA ? GO:0009507 ... O19928 26757821
    4732 4yuu:b2 (2.77) BS09 CLA ? GO:0009507 ... O19928 26757821
    4733 4yuu:b2 (2.77) BS10 CLA ? GO:0009507 ... O19928 26757821
    4734 4yuu:b2 (2.77) BS11 CLA ? GO:0009507 ... O19928 26757821
    4735 4yuu:b2 (2.77) BS12 CLA ? GO:0009507 ... O19928 26757821
    4736 4yuu:b2 (2.77) BS13 CLA ? GO:0009507 ... O19928 26757821
    4737 4yuu:b2 (2.77) BS14 CLA ? GO:0009507 ... O19928 26757821
    4738 4yuu:b2 (2.77) BS15 CLA ? GO:0009507 ... O19928 26757821
    4739 4yuu:b2 (2.77) BS16 CLA ? GO:0009507 ... O19928 26757821
    4740 4yuu:c1 (2.77) BS02 CLA ? GO:0005737 ... Q9TM46 26757821
    4741 4yuu:c1 (2.77) BS03 CLA ? GO:0005737 ... Q9TM46 26757821
    4742 4yuu:c1 (2.77) BS04 CLA ? GO:0005737 ... Q9TM46 26757821
    4743 4yuu:c1 (2.77) BS05 CLA ? GO:0005737 ... Q9TM46 26757821
    4744 4yuu:c1 (2.77) BS06 CLA ? GO:0005737 ... Q9TM46 26757821
    4745 4yuu:c1 (2.77) BS07 CLA ? GO:0005737 ... Q9TM46 26757821
    4746 4yuu:c1 (2.77) BS08 CLA ? GO:0005737 ... Q9TM46 26757821
    4747 4yuu:c1 (2.77) BS09 CLA ? GO:0005737 ... Q9TM46 26757821
    4748 4yuu:c1 (2.77) BS10 CLA ? GO:0005737 ... Q9TM46 26757821
    4749 4yuu:c1 (2.77) BS11 CLA ? GO:0005737 ... Q9TM46 26757821
    4750 4yuu:c1 (2.77) BS12 CLA ? GO:0005737 ... Q9TM46 26757821
    4751 4yuu:c1 (2.77) BS13 CLA ? GO:0005737 ... Q9TM46 26757821
    4752 4yuu:c1 (2.77) BS14 CLA ? GO:0005737 ... Q9TM46 26757821
    4753 4yuu:c2 (2.77) BS02 CLA ? GO:0005737 ... Q9TM46 26757821
    4754 4yuu:c2 (2.77) BS03 CLA ? GO:0005737 ... Q9TM46 26757821
    4755 4yuu:c2 (2.77) BS04 CLA ? GO:0005737 ... Q9TM46 26757821
    4756 4yuu:c2 (2.77) BS05 CLA ? GO:0005737 ... Q9TM46 26757821
    4757 4yuu:c2 (2.77) BS06 CLA ? GO:0005737 ... Q9TM46 26757821
    4758 4yuu:c2 (2.77) BS07 CLA ? GO:0005737 ... Q9TM46 26757821
    4759 4yuu:c2 (2.77) BS08 CLA ? GO:0005737 ... Q9TM46 26757821
    4760 4yuu:c2 (2.77) BS09 CLA ? GO:0005737 ... Q9TM46 26757821
    4761 4yuu:c2 (2.77) BS10 CLA ? GO:0005737 ... Q9TM46 26757821
    4762 4yuu:c2 (2.77) BS11 CLA ? GO:0005737 ... Q9TM46 26757821
    4763 4yuu:c2 (2.77) BS12 CLA ? GO:0005737 ... Q9TM46 26757821
    4764 4yuu:c2 (2.77) BS13 CLA ? GO:0005737 ... Q9TM46 26757821
    4765 4yuu:c2 (2.77) BS14 CLA ? GO:0005737 ... Q9TM46 26757821
    4766 4yuu:d1 (2.77) BS02 CLA 1.10.3.9 GO:0005506 ... Q9TM47 26757821
    4767 4yuu:d1 (2.77) BS06 CLA 1.10.3.9 GO:0005506 ... Q9TM47 26757821
    4768 4yuu:d1 (2.77) BS07 CLA 1.10.3.9 GO:0005506 ... Q9TM47 26757821
    4769 4yuu:d1 (2.77) BS09 CLA 1.10.3.9 GO:0005506 ... Q9TM47 26757821
    4770 4yuu:d1 (2.77) BS10 CLA 1.10.3.9 GO:0005506 ... Q9TM47 26757821
    4771 4yuu:d2 (2.77) BS02 CLA 1.10.3.9 GO:0005506 ... Q9TM47 26757821
    4772 4yuu:d2 (2.77) BS06 CLA 1.10.3.9 GO:0005506 ... Q9TM47 26757821
    4773 4yuu:d2 (2.77) BS07 CLA 1.10.3.9 GO:0005506 ... Q9TM47 26757821
    4774 4yuu:d2 (2.77) BS08 CLA 1.10.3.9 GO:0005506 ... Q9TM47 26757821
    4775 4yuu:d2 (2.77) BS09 CLA 1.10.3.9 GO:0005506 ... Q9TM47 26757821
    4776 4yuu:h1 (2.77) BS02 CLA ? GO:0009507 ... O19925 26757821
    4777 4yuu:h1 (2.77) BS03 CLA ? GO:0009507 ... O19925 26757821
    4778 4yuu:h1 (2.77) BS04 CLA ? GO:0009507 ... O19925 26757821
    4779 4yuu:h2 (2.77) BS01 CLA ? GO:0009507 ... O19925 26757821
    4780 4yuu:h2 (2.77) BS02 CLA ? GO:0009507 ... O19925 26757821
    4781 4yuu:i1 (2.77) BS01 CLA ? GO:0005737 ... O19882 26757821
    4782 4yuu:i2 (2.77) BS01 CLA ? GO:0005737 ... O19882 26757821
    4783 4yuu:i2 (2.77) BS02 CLA ? GO:0005737 ... O19882 26757821
    4784 4yuu:k1 (2.77) BS02 CLA ? GO:0005737 ... Q9TLR0 26757821
    4785 4yuu:k1 (2.77) BS03 CLA ? GO:0005737 ... Q9TLR0 26757821
    4786 4yuu:k2 (2.77) BS02 CLA ? GO:0005737 ... Q9TLR0 26757821
    4787 4yuu:k2 (2.77) BS03 CLA ? GO:0005737 ... Q9TLR0 26757821
    4788 4yuu:m1 (2.77) BS01 CLA N/A GO:0009523 ... N/A 26757821
    4789 4yuu:m2 (2.77) BS02 CLA N/A GO:0009523 ... N/A 26757821
    4790 5b5e:A (1.87) BS03 CLA 1.10.3.9 GO:0005506 ... P51765 28102667
    4791 5b5e:A (1.87) BS04 CLA 1.10.3.9 GO:0005506 ... P51765 28102667
    4792 5b5e:A (1.87) BS06 CLA 1.10.3.9 GO:0005506 ... P51765 28102667
    4793 5b5e:A (1.87) BS08 CLA 1.10.3.9 GO:0005506 ... P51765 28102667
    4794 5b5e:A (1.87) BS09 CLA 1.10.3.9 GO:0005506 ... P51765 28102667
    4795 5b5e:B (1.87) BS01 CLA ? GO:0009521 ... D0VWR1 28102667
    4796 5b5e:B (1.87) BS02 CLA ? GO:0009521 ... D0VWR1 28102667
    4797 5b5e:B (1.87) BS03 CLA ? GO:0009521 ... D0VWR1 28102667
    4798 5b5e:B (1.87) BS04 CLA ? GO:0009521 ... D0VWR1 28102667
    4799 5b5e:B (1.87) BS05 CLA ? GO:0009521 ... D0VWR1 28102667
    4800 5b5e:B (1.87) BS06 CLA ? GO:0009521 ... D0VWR1 28102667

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218