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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
Download all results in tab-seperated text for 733 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    201 2v68:H (2.3) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    202 2v69:A (2.8) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    203 2v69:A (2.8) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    204 2v69:B (2.8) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    205 2v69:B (2.8) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    206 2v69:C (2.8) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    207 2v69:C (2.8) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    208 2v69:D (2.8) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    209 2v69:D (2.8) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    210 2v69:E (2.8) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    211 2v69:E (2.8) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    212 2v69:F (2.8) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    213 2v69:F (2.8) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    214 2v69:G (2.8) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    215 2v69:G (2.8) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    216 2v69:H (2.8) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    217 2v69:H (2.8) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    218 2v6a:A (1.5) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    219 2v6a:A (1.5) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    220 2v6a:B (1.5) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    221 2v6a:B (1.5) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    222 2v6a:C (1.5) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    223 2v6a:C (1.5) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    224 2v6a:D (1.5) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    225 2v6a:D (1.5) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    226 2v6a:E (1.5) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    227 2v6a:E (1.5) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    228 2v6a:F (1.5) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    229 2v6a:F (1.5) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    230 2v6a:G (1.5) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    231 2v6a:G (1.5) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    232 2v6a:H (1.5) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    233 2v6a:H (1.5) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 17824672
    234 2vdh:A (2.3) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    235 2vdh:A (2.3) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    236 2vdh:B (2.3) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    237 2vdh:B (2.3) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    238 2vdh:C (2.3) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    239 2vdh:C (2.3) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    240 2vdh:D (2.3) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    241 2vdh:D (2.3) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    242 2vdh:E (2.3) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    243 2vdh:E (2.3) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    244 2vdh:F (2.3) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    245 2vdh:F (2.3) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    246 2vdh:G (2.3) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    247 2vdh:G (2.3) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    248 2vdh:H (2.3) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    249 2vdh:H (2.3) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    250 2vdi:A (2.65) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    251 2vdi:A (2.65) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    252 2vdi:B (2.65) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    253 2vdi:B (2.65) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    254 2vdi:C (2.65) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    255 2vdi:C (2.65) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    256 2vdi:D (2.65) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    257 2vdi:D (2.65) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    258 2vdi:E (2.65) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    259 2vdi:E (2.65) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    260 2vdi:F (2.65) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    261 2vdi:F (2.65) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    262 2vdi:G (2.65) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    263 2vdi:G (2.65) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    264 2vdi:H (2.65) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    265 2vdi:H (2.65) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 18072944
    266 3a12:A (2.3) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    267 3a12:B (2.3) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    268 3a12:C (2.3) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    269 3a12:D (2.3) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    270 3a12:E (2.3) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    271 3a12:F (2.3) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    272 3a12:G (2.3) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    273 3a12:H (2.3) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    274 3a12:I (2.3) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    275 3a12:J (2.3) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    276 3a13:A (2.34) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 N/A
    277 3a13:B (2.34) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 N/A
    278 3a13:C (2.34) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 N/A
    279 3a13:D (2.34) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 N/A
    280 3a13:E (2.34) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 N/A
    281 3a13:F (2.34) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 N/A
    282 3a13:G (2.34) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 N/A
    283 3a13:H (2.34) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 N/A
    284 3a13:I (2.34) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 N/A
    285 3a13:J (2.34) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 N/A
    286 3kdn:A (2.09) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    287 3kdn:A (2.09) BS03 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    288 3kdn:B (2.09) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    289 3kdn:B (2.09) BS03 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    290 3kdn:C (2.09) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    291 3kdn:C (2.09) BS03 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    292 3kdn:D (2.09) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    293 3kdn:D (2.09) BS03 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    294 3kdn:E (2.09) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    295 3kdn:E (2.09) BS03 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    296 3kdn:F (2.09) BS01 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    297 3kdn:F (2.09) BS03 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    298 3kdn:G (2.09) BS01 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    299 3kdn:G (2.09) BS03 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    300 3kdn:H (2.09) BS01 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    301 3kdn:H (2.09) BS03 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    302 3kdn:I (2.09) BS01 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    303 3kdn:I (2.09) BS03 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    304 3kdn:J (2.09) BS01 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    305 3kdn:J (2.09) BS03 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    306 3kdo:A (2.36) BS01 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    307 3kdo:A (2.36) BS03 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    308 3kdo:B (2.36) BS01 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    309 3kdo:B (2.36) BS03 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    310 3kdo:C (2.36) BS01 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    311 3kdo:C (2.36) BS03 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    312 3kdo:D (2.36) BS01 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    313 3kdo:D (2.36) BS03 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    314 3kdo:E (2.36) BS01 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    315 3kdo:E (2.36) BS03 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    316 3kdo:F (2.36) BS01 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    317 3kdo:F (2.36) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    318 3kdo:G (2.36) BS01 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    319 3kdo:G (2.36) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    320 3kdo:H (2.36) BS01 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    321 3kdo:H (2.36) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    322 3kdo:I (2.36) BS01 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    323 3kdo:I (2.36) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    324 3kdo:J (2.36) BS01 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    325 3kdo:J (2.36) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 20926376
    326 3wqp:A (2.25) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 N/A
    327 3wqp:B (2.25) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 N/A
    328 3wqp:C (2.25) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 N/A
    329 3wqp:D (2.25) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 N/A
    330 3wqp:E (2.25) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 N/A
    331 3wqp:F (2.25) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 N/A
    332 3wqp:G (2.25) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 N/A
    333 3wqp:H (2.25) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 N/A
    334 3wqp:I (2.25) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 N/A
    335 3wqp:J (2.25) BS02 CAP 4.1.1.39 GO:0000287 ... O93627 N/A
    336 3zxw:A (2.1) BS02 CAP 4.1.1.39 GO:0000287 ... Q8DIS5 N/A
    337 3zxw:C (2.1) BS02 CAP 4.1.1.39 GO:0000287 ... Q8DIS5 N/A
    338 3zxw:E (2.1) BS02 CAP 4.1.1.39 GO:0000287 ... Q8DIS5 N/A
    339 3zxw:G (2.1) BS02 CAP 4.1.1.39 GO:0000287 ... Q8DIS5 N/A
    340 4lf1:A (2.38) BS01 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 24942737
    341 4lf1:A (2.38) BS03 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 24942737
    342 4lf1:B (2.38) BS01 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 24942737
    343 4lf1:B (2.38) BS02 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 24942737
    344 4lf1:C (2.38) BS01 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 24942737
    345 4lf1:C (2.38) BS03 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 24942737
    346 4lf1:D (2.38) BS01 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 24942737
    347 4lf1:D (2.38) BS02 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 24942737
    348 4lf1:E (2.38) BS01 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 24942737
    349 4lf1:E (2.38) BS03 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 24942737
    350 4lf1:F (2.38) BS01 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 24942737
    351 4lf1:F (2.38) BS02 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 24942737
    352 4rub:A (2.7) BS02 CAP 4.1.1.39 GO:0000287 ... P00876 3681999
    353 4rub:A (2.7) BS03 CAP 4.1.1.39 GO:0000287 ... P00876 3681999
    354 4rub:B (2.7) BS02 CAP 4.1.1.39 GO:0000287 ... P00876 3681999
    355 4rub:B (2.7) BS03 CAP 4.1.1.39 GO:0000287 ... P00876 3681999
    356 4rub:C (2.7) BS01 CAP 4.1.1.39 GO:0000287 ... P00876 3681999
    357 4rub:C (2.7) BS03 CAP 4.1.1.39 GO:0000287 ... P00876 3681999
    358 4rub:D (2.7) BS01 CAP 4.1.1.39 GO:0000287 ... P00876 3681999
    359 4rub:D (2.7) BS03 CAP 4.1.1.39 GO:0000287 ... P00876 3681999
    360 5c2g:A (2.597) BS01 CAP 4.1.1.39 GO:0000287 ... A0A0X1KHE5 26617072
    361 5c2g:A (2.597) BS03 CAP 4.1.1.39 GO:0000287 ... A0A0X1KHE5 26617072
    362 5c2g:B (2.597) BS01 CAP 4.1.1.39 GO:0000287 ... A0A0X1KHE5 26617072
    363 5c2g:B (2.597) BS03 CAP 4.1.1.39 GO:0000287 ... A0A0X1KHE5 26617072
    364 5c2g:C (2.597) BS01 CAP 4.1.1.39 GO:0000287 ... A0A0X1KHE5 26617072
    365 5c2g:C (2.597) BS02 CAP 4.1.1.39 GO:0000287 ... A0A0X1KHE5 26617072
    366 5c2g:D (2.597) BS01 CAP 4.1.1.39 GO:0000287 ... A0A0X1KHE5 26617072
    367 5c2g:D (2.597) BS03 CAP 4.1.1.39 GO:0000287 ... A0A0X1KHE5 26617072
    368 5c2g:E (2.597) BS01 CAP 4.1.1.39 GO:0000287 ... A0A0X1KHE5 26617072
    369 5c2g:E (2.597) BS02 CAP 4.1.1.39 GO:0000287 ... A0A0X1KHE5 26617072
    370 5c2g:F (2.597) BS01 CAP 4.1.1.39 GO:0000287 ... A0A0X1KHE5 26617072
    371 5c2g:F (2.597) BS02 CAP 4.1.1.39 GO:0000287 ... A0A0X1KHE5 26617072
    372 5han:A (2.04) BS01 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    373 5han:A (2.04) BS03 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    374 5han:B (2.04) BS01 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    375 5han:B (2.04) BS02 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    376 5han:C (2.04) BS01 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    377 5han:C (2.04) BS03 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    378 5han:D (2.04) BS01 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    379 5han:D (2.04) BS02 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    380 5han:E (2.04) BS01 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    381 5han:E (2.04) BS03 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    382 5han:F (2.04) BS01 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    383 5han:F (2.04) BS02 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    384 5han:G (2.04) BS01 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    385 5han:G (2.04) BS03 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    386 5han:H (2.04) BS01 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    387 5han:H (2.04) BS02 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    388 5han:I (2.04) BS01 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    389 5han:I (2.04) BS03 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    390 5han:J (2.04) BS01 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    391 5han:J (2.04) BS02 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    392 5han:K (2.04) BS01 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    393 5han:K (2.04) BS03 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    394 5han:L (2.04) BS01 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    395 5han:L (2.04) BS02 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    396 5hao:A (2.182) BS01 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    397 5hao:A (2.182) BS03 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    398 5hao:B (2.182) BS01 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    399 5hao:B (2.182) BS02 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A
    400 5hao:C (2.182) BS01 CAP 4.1.1.39 GO:0000287 ... Q6N0W9 N/A

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218