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BioLiP
Download all results in tab-seperated text for 128 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1n3q:B (2.2) BS01 BDF ? GO:0030246 ... Q8GSD2 12595543
    2 1ovp:A (1.4) BS01 BDF ? GO:0030246 ... Q9HYN5 12909014
    3 2fa1:B (1.7) BS01 BDF ? GO:0003677 ... P16684 16672238
    4 3oay:H (1.95) BS01 BDF N/A N/A N/A 20852065 PDBbind: -logKd/Ki=1.70, IC50~20mM
    5 3oay:M (1.95) BS01 BDF N/A N/A N/A 20852065
    6 4xwz:A (1.9) BS03 BDF ? GO:0000166 ... O42629 26873906
    7 4xwz:B (1.9) BS03 BDF ? GO:0000166 ... O42629 26873906
    8 5ikm:A (1.9) BS02 BDF 3.4.21.91
    3.6.1.15
    3.6.4.13    		 GO:0004482 ... I6XG39 N/A
    9 5u9c:A (1.9) BS01 BDF 1.1.1.133 GO:0008831 ... Q56905 N/A
    10 5u9c:C (1.9) BS01 BDF 1.1.1.133 GO:0008831 ... Q56905 N/A
    11 5u9c:C (1.9) BS02 BDF 1.1.1.133 GO:0008831 ... Q56905 N/A
    12 5v36:A (1.88) BS02 BDF 1.8.1.7 GO:0000166 ... Q8DUR5 N/A
    13 5v36:B (1.88) BS02 BDF 1.8.1.7 GO:0000166 ... Q8DUR5 N/A
    14 5vdn:A (1.55) BS02 BDF 1.8.1.7 GO:0000166 ... Q8CZL0 N/A
    15 5vdn:B (1.55) BS02 BDF 1.8.1.7 GO:0000166 ... Q8CZL0 N/A
    16 6lgi:A (1.6) BS05 BDF 3.2.1.20 GO:0005975 ... A0A077JI83 32381508
    17 6lgi:B (1.6) BS05 BDF 3.2.1.20 GO:0005975 ... A0A077JI83 32381508
    18 6m0e:A (1.35) BS02 BDF 2.4.1.10 GO:0009758 ... B2IF78 32752982
    19 6m0e:A (1.35) BS03 BDF 2.4.1.10 GO:0009758 ... B2IF78 32752982
    20 6m0e:A (1.35) BS04 BDF 2.4.1.10 GO:0009758 ... B2IF78 32752982
    21 6stz:A (1.14) BS01 BDF ? N/A Q8XXK6 31825399
    22 6stz:A (1.14) BS02 BDF ? N/A Q8XXK6 31825399
    23 6stz:A (1.14) BS03 BDF ? N/A Q8XXK6 31825399
    24 6stz:B (1.14) BS01 BDF ? N/A Q8XXK6 31825399
    25 6stz:B (1.14) BS02 BDF ? N/A Q8XXK6 31825399
    26 6stz:B (1.14) BS03 BDF ? N/A Q8XXK6 31825399
    27 6stz:C (1.14) BS01 BDF ? N/A Q8XXK6 31825399
    28 6stz:C (1.14) BS02 BDF ? N/A Q8XXK6 31825399
    29 6stz:C (1.14) BS03 BDF ? N/A Q8XXK6 31825399
    30 6stz:D (1.14) BS01 BDF ? N/A Q8XXK6 31825399
    31 6stz:D (1.14) BS02 BDF ? N/A Q8XXK6 31825399
    32 6stz:D (1.14) BS03 BDF ? N/A Q8XXK6 31825399
    33 6stz:E (1.14) BS01 BDF ? N/A Q8XXK6 31825399
    34 6stz:E (1.14) BS02 BDF ? N/A Q8XXK6 31825399
    35 6stz:E (1.14) BS03 BDF ? N/A Q8XXK6 31825399
    36 6stz:F (1.14) BS01 BDF ? N/A Q8XXK6 31825399
    37 6stz:F (1.14) BS02 BDF ? N/A Q8XXK6 31825399
    38 6stz:F (1.14) BS03 BDF ? N/A Q8XXK6 31825399
    39 6w4h:A (1.8) BS02 BDF 2.1.1.56
    2.1.1.57
    2.7.7.48
    2.7.7.50
    3.1.13.-
    3.4.19.12
    3.4.22.-
    3.4.22.69
    3.6.4.12
    3.6.4.13
    4.6.1.-    		 GO:0004483 ... P0DTD1 32994211
    40 6w4h:B (1.8) BS03 BDF 2.1.1.56
    2.1.1.57
    2.7.7.48
    2.7.7.50
    3.1.13.-
    3.4.19.12
    3.4.22.-
    3.4.22.69
    3.6.4.12
    3.6.4.13
    4.6.1.-    		 GO:0003723 ... P0DTD1 32994211
    41 6wn8:A (2.7) BS01 BDF 2.4.2.9 GO:0000287 ... A6TCB0 36695589
    42 6wn8:A (2.7) BS02 BDF 2.4.2.9 GO:0000287 ... A6TCB0 36695589
    43 6wn8:B (2.7) BS01 BDF 2.4.2.9 GO:0000287 ... A6TCB0 36695589
    44 6wn8:B (2.7) BS02 BDF 2.4.2.9 GO:0000287 ... A6TCB0 36695589
    45 6wn8:E (2.7) BS01 BDF 2.4.2.9 GO:0000287 ... A6TCB0 36695589
    46 6wn8:E (2.7) BS02 BDF 2.4.2.9 GO:0000287 ... A6TCB0 36695589
    47 6z5g:A (1.278) BS01 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    48 6z5m:A (1.6) BS03 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    49 6z5m:A (1.6) BS04 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    50 6z5p:A (1.42) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    51 6z5p:A (1.42) BS03 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    52 6z5p:B (1.42) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    53 6z5p:B (1.42) BS03 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    54 6z5q:A (1.29) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    55 6z5q:A (1.29) BS03 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    56 6z5q:B (1.29) BS03 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    57 6z5q:B (1.29) BS04 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    58 6z5w:A (1.187) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    59 6z5w:A (1.187) BS03 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    60 6z5x:A (1.14) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    61 6z5x:A (1.14) BS03 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    62 6z5z:A (1.124) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    63 6z5z:A (1.124) BS03 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    64 6z60:A (1.166) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    65 6z60:A (1.166) BS03 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    66 6z62:A (1.156) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    67 6z62:A (1.156) BS03 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    68 6zum:A (1.589) BS01 BDF ? GO:0030246 ... A0A0S4TLR1 N/A
    69 6zum:A (1.589) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 N/A
    70 7alf:A (1.261) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    71 7alf:A (1.261) BS03 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    72 7alf:B (1.261) BS03 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    73 7alf:B (1.261) BS04 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    74 7alg:A (1.452) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    75 7alg:A (1.452) BS03 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    76 7alg:B (1.452) BS03 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    77 7alg:B (1.452) BS04 BDF ? GO:0030246 ... A0A0S4TLR1 33470808
    78 7cj5:A (1.8) BS03 BDF 5.1.3.31 GO:0016853 ... A0A172U6X0 33838083
    79 7l6r:B (1.98) BS02 BDF 2.1.1.56
    2.1.1.57
    2.7.7.48
    2.7.7.50
    3.1.13.-
    3.4.19.12
    3.4.22.-
    3.4.22.69
    3.6.4.12
    3.6.4.13
    4.6.1.-    		 GO:0003723 ... P0DTD1 34131072
    80 7l6t:B (1.78) BS03 BDF 2.1.1.56
    2.1.1.57
    2.7.7.48
    2.7.7.50
    3.1.13.-
    3.4.19.12
    3.4.22.-
    3.4.22.69
    3.6.4.12
    3.6.4.13
    4.6.1.-    		 GO:0003723 ... P0DTD1 34131072
    81 7pr5:A (1.94) BS01 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    82 7pr5:A (1.94) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    83 7pr5:A (1.94) BS04 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    84 7pr5:B (1.94) BS01 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    85 7pr5:B (1.94) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    86 7pr5:B (1.94) BS04 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    87 7pr5:C (1.94) BS01 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    88 7pr5:C (1.94) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    89 7pr5:C (1.94) BS03 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    90 7pr5:D (1.94) BS01 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    91 7pr5:D (1.94) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    92 7pr5:D (1.94) BS04 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    93 7pr5:E (1.94) BS01 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    94 7pr5:E (1.94) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    95 7pr5:E (1.94) BS03 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    96 7pr5:F (1.94) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    97 7pr5:F (1.94) BS03 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    98 7pr5:F (1.94) BS04 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    99 7pr5:G (1.94) BS01 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    100 7pr5:G (1.94) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    101 7pr5:G (1.94) BS03 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    102 7pr5:H (1.94) BS01 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    103 7pr5:I (1.94) BS01 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    104 7pr5:I (1.94) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    105 7pr5:I (1.94) BS03 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    106 7pr5:J (1.94) BS01 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    107 7pr5:J (1.94) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    108 7pr5:J (1.94) BS04 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    109 7pr5:K (1.94) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    110 7pr5:K (1.94) BS03 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    111 7pr5:K (1.94) BS04 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    112 7pr5:L (1.94) BS01 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    113 7pr5:L (1.94) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    114 7pr5:L (1.94) BS03 BDF ? GO:0030246 ... A0A0S4TLR1 35529063
    115 8c9y:A (1.18) BS03 BDF ? GO:0030246 ... A0A0S4TLR1 37314405
    116 8c9y:A (1.18) BS04 BDF ? GO:0030246 ... A0A0S4TLR1 37314405
    117 8c9z:A (1.18) BS01 BDF ? GO:0030246 ... A0A0S4TLR1 37314405
    118 8c9z:A (1.18) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 37314405
    119 8i2r:A (1.36) BS02 BDF 2.4.1.10 GO:0009758 ... B2IF78 37280168
    120 8i2r:A (1.36) BS03 BDF 2.4.1.10 GO:0009758 ... B2IF78 37280168
    121 8q6a:A (2.61) BS01 BDF ? GO:0030246 ... A0A0S4TLR1 38463617
    122 8q6b:A (1.52) BS02 BDF ? GO:0030246 ... A0A0S4TLR1 38463617
    123 8q6b:A (1.52) BS04 BDF ? GO:0030246 ... A0A0S4TLR1 38463617
    124 8q6c:A (1.38) BS01 BDF ? GO:0030246 ... A0A0S4TLR1 38463617
    125 8uvu:A (3.0) BS01 BDF ? GO:0001582 ... B3GTD7 38447670
    126 8uvu:B (3.0) BS01 BDF ? GO:0001582 ... B3GTD7 38447670
    127 8uvu:C (3.0) BS01 BDF ? GO:0001582 ... B3GTD7 38447670
    128 8uvu:D (3.0) BS01 BDF ? GO:0001582 ... B3GTD7 38447670
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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