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BioLiP Library
Download all results in tab-seperated text for 38 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 2c05:A (1.86) BS01 B4P 4.6.1.18 GO:0003676 ... P10153 16401072 MOAD: Ki=1.9uM
    2 2c95:A (1.71) BS01 B4P 2.7.4.10
    2.7.4.3
    2.7.4.6    		 GO:0001520 ... P00568 N/A
    3 2c95:B (1.71) BS01 B4P 2.7.4.10
    2.7.4.3
    2.7.4.6    		 GO:0001520 ... P00568 N/A
    4 2c9y:A (2.1) BS01 B4P 2.7.4.3 GO:0004017 ... P54819 N/A
    5 2e1z:A (1.98) BS01 B4P 2.7.2.15 GO:0005524 ... O06961 17894350
    6 2e20:A (2.4) BS01 B4P 2.7.2.15 GO:0005524 ... O06961 17894350
    7 2xjc:A (2.0) BS02 B4P 2.7.1.77
    3.1.3.5
    3.1.3.99    		 GO:0000255 ... P49902 21396942
    8 2zt5:A (2.5) BS01 B4P 2.7.7.-
    6.1.1.14    		 GO:0000166 ... P41250 N/A
    9 2zxf:A (3.4) BS01 B4P 2.7.7.-
    6.1.1.14    		 GO:0000166 ... P41250 N/A
    10 3a74:A (1.8) BS01 B4P 6.1.1.6 GO:0000049 ... Q9RHV9 N/A
    11 3a74:B (1.8) BS01 B4P 6.1.1.6 GO:0000049 ... Q9RHV9 N/A
    12 3a74:C (1.8) BS01 B4P 6.1.1.6 GO:0000049 ... Q9RHV9 N/A
    13 3a74:D (1.8) BS01 B4P 6.1.1.6 GO:0000049 ... Q9RHV9 N/A
    14 3bho:A (1.8) BS01 B4P ? GO:0003682 ... O43809 18445629 MOAD: Kd=2.44uM
    15 3i7v:A (1.95) BS02 B4P ? GO:0004081 ... O66548 20124691
    16 3i7v:B (1.95) BS01 B4P ? GO:0004081 ... O66548 20124691
    17 3l2b:A (2.27) BS01 B4P 3.6.1.1 N/A Q8XIQ9 20303981
    18 3l2b:B (2.27) BS01 B4P 3.6.1.1 N/A Q8XIQ9 20303981
    19 3loo:A (2.0) BS01 B4P N/A GO:0004001 ... N/A 21247194 MOAD: Ki=860nM
    PDBbind: -logKd/Ki=6.07, Ki=860nM
    20 3loo:B (2.0) BS01 B4P N/A GO:0004001 ... N/A 21247194 MOAD: Ki=860nM
    21 3loo:C (2.0) BS01 B4P N/A GO:0004001 ... N/A 21247194 MOAD: Ki=860nM
    22 3rqx:A (1.6) BS01 B4P 4.2.1.136 GO:0005524 ... P94368 22940582
    23 3rqx:A (1.6) BS02 B4P 4.2.1.136 GO:0005524 ... P94368 22940582
    24 3rqx:A (1.6) BS03 B4P 4.2.1.136 GO:0005524 ... P94368 22940582
    25 3rsf:A (2.3) BS02 B4P 4.2.1.136
    5.1.99.6    		 GO:0005524 ... Q9X024 22940582
    26 4i5v:A (2.696) BS01 B4P 2.7.7.5
    2.7.7.53    		 GO:0003877 ... P22108 23628156
    27 4i5v:B (2.696) BS01 B4P 2.7.7.5
    2.7.7.53    		 GO:0003877 ... P22108 23628156
    28 5yzx:A (3.2) BS01 B4P 6.1.1.6 GO:0000049 ... P0A8N5 N/A
    29 5yzx:B (3.2) BS01 B4P 6.1.1.6 GO:0000049 ... P0A8N5 N/A
    30 5yzx:C (3.2) BS01 B4P 6.1.1.6 GO:0000049 ... P0A8N5 N/A
    31 6f2y:A (2.4) BS01 B4P 3.1.4.1
    3.6.1.9    		 GO:0003676 ... P97675 30022031
    32 6f2y:B (2.4) BS01 B4P 3.1.4.1
    3.6.1.9    		 GO:0003676 ... P97675 30022031
    33 6j64:B (0.95) BS01 B4P 3.4.22.-
    3.9.1.-    		 GO:0000118 ... P49773 31604935
    34 6j65:B (1.42) BS01 B4P 3.4.22.-
    3.9.1.-    		 GO:0000118 ... P49773 31604935
    35 6j65:E (1.42) BS01 B4P 3.4.22.-
    3.9.1.-    		 GO:0000118 ... P49773 31604935
    36 7oj1:A (2.44) BS01 B4P 1.1.1.205 GO:0003824 ... P21879 35953658
    37 7oj1:B (2.44) BS01 B4P 1.1.1.205 GO:0003824 ... P21879 35953658
    38 7sp3:A (1.6) BS01 B4P 3.6.1.- GO:0000287 ... P0A776 35131855
    Reference:
    • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023)(download the PDF file).
    • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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