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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
Download all results in tab-seperated text for 9664 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    3201 6fvw:J (4.5) BS01 ATP ? GO:0000502 ... Q01939 30067984
    3202 6fvw:J (4.5) BS02 ATP ? GO:0000502 ... Q01939 30067984
    3203 6fvw:K (4.5) BS02 ATP ? GO:0000502 ... P33298 30067984
    3204 6fvw:M (4.5) BS01 ATP ? GO:0000502 ... P33297 30067984
    3205 6fvx:H (4.9) BS01 ATP ? GO:0000502 ... P33299 30067984
    3206 6fvx:H (4.9) BS02 ATP ? GO:0000502 ... P33299 30067984
    3207 6fvx:I (4.9) BS01 ATP ? GO:0005524 ... P40327 30067984
    3208 6fvx:I (4.9) BS02 ATP ? GO:0005524 ... P40327 30067984
    3209 6fvx:K (4.9) BS01 ATP ? GO:0000502 ... P33298 30067984
    3210 6fvx:L (4.9) BS01 ATP ? GO:0005524 ... P53549 30067984
    3211 6fvx:M (4.9) BS01 ATP ? GO:0000502 ... P33297 30067984
    3212 6fvx:M (4.9) BS02 ATP ? GO:0000502 ... P33297 30067984
    3213 6fvy:H (6.1) BS01 ATP ? GO:0000502 ... P33299 30067984
    3214 6fvy:I (6.1) BS01 ATP ? GO:0005524 ... P40327 30067984
    3215 6fvy:I (6.1) BS02 ATP ? GO:0005524 ... P40327 30067984
    3216 6fvy:J (6.1) BS01 ATP ? GO:0000502 ... Q01939 30067984
    3217 6fvy:J (6.1) BS02 ATP ? GO:0000502 ... Q01939 30067984
    3218 6fvy:K (6.1) BS01 ATP ? GO:0000502 ... P33298 30067984
    3219 6fvy:K (6.1) BS02 ATP ? GO:0000502 ... P33298 30067984
    3220 6fvy:L (6.1) BS01 ATP ? GO:0005524 ... P53549 30067984
    3221 6fzb:A (2.05) BS04 ATP 2.7.7.47 GO:0005524 ... Q8ZPX9 29871922
    3222 6fzb:B (2.05) BS04 ATP 2.7.7.47 GO:0005524 ... Q8ZPX9 29871922
    3223 6gfa:A (2.0) BS01 ATP ? GO:0005524 ... Q92598 31068676
    3224 6gfh:A (2.65) BS02 ATP 2.7.1.158 GO:0005524 ... Q93YN9 30160967
    3225 6gfh:B (2.65) BS02 ATP 2.7.1.158 GO:0005524 ... Q93YN9 30160967
    3226 6gjq:A (2.49) BS01 ATP 5.6.1.6 GO:0005524 ... P13569 31201318
    3227 6gjq:C (2.49) BS01 ATP 5.6.1.6 GO:0005524 ... P13569 31201318
    3228 6gjq:E (2.49) BS01 ATP 5.6.1.6 GO:0005524 ... P13569 31201318
    3229 6gjq:G (2.49) BS01 ATP 5.6.1.6 GO:0005524 ... P13569 31201318
    3230 6gjs:A (1.95) BS02 ATP 5.6.1.6 GO:0005524 ... P13569 31201318
    3231 6gk4:A (2.91) BS02 ATP 5.6.1.6 GO:0005524 ... P13569 31201318
    3232 6gk4:D (2.91) BS01 ATP 5.6.1.6 GO:0005524 ... P13569 31201318
    3233 6gkd:A (2.99) BS03 ATP 5.6.1.6 GO:0005524 ... P13569 31201318
    3234 6gkd:F (2.99) BS03 ATP 5.6.1.6 GO:0005524 ... P13569 31201318
    3235 6gkd:I (2.99) BS04 ATP 5.6.1.6 GO:0005524 ... P13569 31201318
    3236 6gkd:L (2.99) BS02 ATP 5.6.1.6 GO:0005524 ... P13569 31201318
    3237 6gkd:O (2.99) BS02 ATP 5.6.1.6 GO:0005524 ... P13569 31201318
    3238 6gkd:R (2.99) BS02 ATP 5.6.1.6 GO:0005524 ... P13569 31201318
    3239 6gkm:A (3.87) BS04 ATP 3.6.4.13 GO:0002376 ... Q8R5F7 30449722
    3240 6gmd:A (1.66) BS02 ATP 2.7.11.1 GO:0004672 ... P68400 29759799
    3241 6gmd:B (1.66) BS03 ATP 2.7.11.1 GO:0004672 ... P68400 29759799
    3242 6grg:2 (2.35) BS03 ATP ? GO:0005737 ... P23184 30661981
    3243 6gu5:A (1.9) BS02 ATP ? GO:0005737 ... P84308 30367742
    3244 6gu5:B (1.9) BS01 ATP ? GO:0005737 ... P84253 30367742
    3245 6guj:A (2.102) BS02 ATP ? GO:0005737 ... P84308 30367742
    3246 6guj:B (2.102) BS01 ATP ? GO:0005737 ... P84253 30367742
    3247 6gvc:A (2.6) BS02 ATP 3.6.4.- GO:0000287 ... P68135 31209295
    3248 6gvc:B (2.6) BS02 ATP 3.6.4.- GO:0000287 ... P68135 31209295
    3249 6gvc:C (2.6) BS02 ATP 3.6.4.- GO:0000287 ... P68135 31209295
    3250 6gvc:D (2.6) BS02 ATP 3.6.4.- GO:0000287 ... P68135 31209295
    3251 6gvt:B (-1.00) BS02 ATP ? N/A Q54324 30595448
    3252 6gvt:B (-1.00) BS03 ATP ? N/A Q54324 30595448
    3253 6gwb:A (1.9) BS01 ATP ? GO:0005737 ... P84308 30278367
    3254 6gwv:A (2.8) BS01 ATP ? GO:0005737 ... P84308 30367742
    3255 6gwv:P (2.8) BS01 ATP ? GO:0005737 ... P84308 30367742
    3256 6gx4:A (1.9) BS02 ATP ? GO:0005737 ... P84308 30367742
    3257 6gx4:B (1.9) BS01 ATP ? GO:0005737 ... P84253 30367742
    3258 6h2j:A (2.6) BS01 ATP 3.1.21.3 GO:0003677 ... P10486 30054276
    3259 6h2j:B (2.6) BS01 ATP 3.1.21.3 GO:0003677 ... P10486 30054276
    3260 6h6w:A (1.9) BS02 ATP ? GO:0005737 ... P84308 30278367
    3261 6h6w:B (1.9) BS01 ATP ? GO:0005737 ... P84253 30278367
    3262 6h73:A (2.3) BS02 ATP ? GO:0005737 ... P84308 30278367
    3263 6h73:B (2.3) BS01 ATP ? GO:0005737 ... P84253 30278367
    3264 6h74:A (1.801) BS02 ATP ? GO:0005737 ... P84308 30278367
    3265 6h74:B (1.801) BS01 ATP ? GO:0005737 ... P84253 30278367
    3266 6h77:A (2.1) BS01 ATP ? GO:0008641 ... Q9GZZ9 30412706 PDBbind: -logKd/Ki=7.33, Kd=46.3nM
    3267 6h77:B (2.1) BS01 ATP ? GO:0008641 ... Q9GZZ9 30412706 PDBbind: -logKd/Ki=7.33, Kd=46.3nM
    3268 6h77:C (2.1) BS01 ATP ? GO:0008641 ... Q9GZZ9 30412706
    3269 6h77:D (2.1) BS01 ATP ? GO:0008641 ... Q9GZZ9 30412706
    3270 6h78:A (2.7) BS01 ATP ? GO:0008641 ... Q9GZZ9 30412706 PDBbind: -logKd/Ki=7.33, Kd=46.3nM
    3271 6h78:B (2.7) BS01 ATP ? GO:0008641 ... Q9GZZ9 30412706 PDBbind: -logKd/Ki=7.33, Kd=46.3nM
    3272 6h78:C (2.7) BS01 ATP ? GO:0008641 ... Q9GZZ9 30412706
    3273 6h78:D (2.7) BS01 ATP ? GO:0008641 ... Q9GZZ9 30412706
    3274 6h78:E (2.7) BS01 ATP ? GO:0008641 ... Q9GZZ9 30412706
    3275 6h78:F (2.7) BS01 ATP ? GO:0008641 ... Q9GZZ9 30412706
    3276 6h78:G (2.7) BS01 ATP ? GO:0008641 ... Q9GZZ9 30412706
    3277 6h78:H (2.7) BS01 ATP ? GO:0008641 ... Q9GZZ9 30412706
    3278 6h78:I (2.7) BS01 ATP ? GO:0008641 ... Q9GZZ9 30412706
    3279 6h78:J (2.7) BS01 ATP ? GO:0008641 ... Q9GZZ9 30412706
    3280 6h78:K (2.7) BS01 ATP ? GO:0008641 ... Q9GZZ9 30412706
    3281 6h78:L (2.7) BS01 ATP ? GO:0008641 ... Q9GZZ9 30412706
    3282 6h78:M (2.7) BS01 ATP ? GO:0008641 ... Q9GZZ9 30412706
    3283 6h78:N (2.7) BS01 ATP ? GO:0008641 ... Q9GZZ9 30412706
    3284 6h78:O (2.7) BS01 ATP ? GO:0008641 ... Q9GZZ9 30412706
    3285 6h78:P (2.7) BS01 ATP ? GO:0008641 ... Q9GZZ9 30412706
    3286 6h8b:A (1.9) BS02 ATP ? GO:0005737 ... P84308 30278367
    3287 6h8h:A (1.901) BS02 ATP ? GO:0005737 ... P84308 30278367
    3288 6ha8:V (3.5) BS04 ATP ? GO:0005524 ... P39115 30126986
    3289 6ha8:V (3.5) BS05 ATP ? GO:0005524 ... P39115 30126986
    3290 6hbu:A (3.09) BS01 ATP 7.6.2.2 GO:0005515 ... Q9UNQ0 30405239
    3291 6hbu:A (3.09) BS03 ATP 7.6.2.2 GO:0005515 ... Q9UNQ0 30405239
    3292 6hbu:B (3.09) BS01 ATP 7.6.2.2 GO:0005515 ... Q9UNQ0 30405239
    3293 6hbu:B (3.09) BS02 ATP 7.6.2.2 GO:0005515 ... Q9UNQ0 30405239
    3294 6he4:H (4.85) BS01 ATP ? GO:0005524 ... O28303 30559193
    3295 6he4:I (4.85) BS01 ATP ? GO:0005524 ... O28303 30559193
    3296 6he4:I (4.85) BS02 ATP ? GO:0005524 ... O28303 30559193
    3297 6he4:J (4.85) BS01 ATP ? GO:0005524 ... O28303 30559193
    3298 6he4:J (4.85) BS02 ATP ? GO:0005524 ... O28303 30559193
    3299 6he4:K (4.85) BS01 ATP ? GO:0005524 ... O28303 30559193
    3300 6he4:L (4.85) BS01 ATP ? GO:0005524 ... O28303 30559193
    3301 6he8:I (6.86) BS01 ATP ? GO:0000502 ... O28303 30559193
    3302 6he8:J (6.86) BS01 ATP ? GO:0000502 ... O28303 30559193
    3303 6he8:J (6.86) BS02 ATP ? GO:0000502 ... O28303 30559193
    3304 6he8:K (6.86) BS01 ATP ? GO:0000502 ... O28303 30559193
    3305 6he8:K (6.86) BS02 ATP ? GO:0000502 ... O28303 30559193
    3306 6he8:L (6.86) BS01 ATP ? GO:0000502 ... O28303 30559193
    3307 6he8:L (6.86) BS02 ATP ? GO:0000502 ... O28303 30559193
    3308 6he8:M (6.86) BS01 ATP ? GO:0000502 ... O28303 30559193
    3309 6he9:H (6.35) BS01 ATP ? GO:0000502 ... O28303 30559193
    3310 6he9:I (6.35) BS01 ATP ? GO:0000502 ... O28303 30559193
    3311 6he9:I (6.35) BS02 ATP ? GO:0000502 ... O28303 30559193
    3312 6he9:J (6.35) BS01 ATP ? GO:0000502 ... O28303 30559193
    3313 6he9:J (6.35) BS02 ATP ? GO:0000502 ... O28303 30559193
    3314 6he9:K (6.35) BS01 ATP ? GO:0000502 ... O28303 30559193
    3315 6he9:K (6.35) BS02 ATP ? GO:0000502 ... O28303 30559193
    3316 6hea:H (7.04) BS01 ATP ? GO:0000502 ... O28303 30559193
    3317 6hea:I (7.04) BS01 ATP ? GO:0000502 ... O28303 30559193
    3318 6hea:I (7.04) BS02 ATP ? GO:0000502 ... O28303 30559193
    3319 6hea:J (7.04) BS01 ATP ? GO:0000502 ... O28303 30559193
    3320 6hea:J (7.04) BS02 ATP ? GO:0000502 ... O28303 30559193
    3321 6hea:K (7.04) BS02 ATP ? GO:0000502 ... O28303 30559193
    3322 6hea:M (7.04) BS01 ATP ? GO:0000502 ... O28303 30559193
    3323 6hec:H (6.95) BS01 ATP ? GO:0000502 ... O28303 30559193
    3324 6hec:H (6.95) BS02 ATP ? GO:0000502 ... O28303 30559193
    3325 6hec:I (6.95) BS01 ATP ? GO:0000502 ... O28303 30559193
    3326 6hec:I (6.95) BS02 ATP ? GO:0000502 ... O28303 30559193
    3327 6hec:J (6.95) BS01 ATP ? GO:0000502 ... O28303 30559193
    3328 6hec:L (6.95) BS01 ATP ? GO:0000502 ... O28303 30559193
    3329 6hec:M (6.95) BS01 ATP ? GO:0000502 ... O28303 30559193
    3330 6hec:M (6.95) BS02 ATP ? GO:0000502 ... O28303 30559193
    3331 6hed:H (6.95) BS01 ATP ? GO:0000502 ... O28303 30559193
    3332 6hed:H (6.95) BS02 ATP ? GO:0000502 ... O28303 30559193
    3333 6hed:I (6.95) BS01 ATP ? GO:0000502 ... O28303 30559193
    3334 6hed:K (6.95) BS01 ATP ? GO:0000502 ... O28303 30559193
    3335 6hed:L (6.95) BS01 ATP ? GO:0000502 ... O28303 30559193
    3336 6hed:L (6.95) BS02 ATP ? GO:0000502 ... O28303 30559193
    3337 6hed:M (6.95) BS01 ATP ? GO:0000502 ... O28303 30559193
    3338 6hed:M (6.95) BS02 ATP ? GO:0000502 ... O28303 30559193
    3339 6hzm:A (3.09) BS01 ATP 7.6.2.2 GO:0005515 ... Q9UNQ0 30405239
    3340 6hzm:A (3.09) BS03 ATP 7.6.2.2 GO:0005515 ... Q9UNQ0 30405239
    3341 6hzm:B (3.09) BS01 ATP 7.6.2.2 GO:0005515 ... Q9UNQ0 30405239
    3342 6hzm:B (3.09) BS02 ATP 7.6.2.2 GO:0005515 ... Q9UNQ0 30405239
    3343 6i4d:A (1.24) BS01 ATP 3.6.4.- GO:0005200 ... Q8I4X0 31199804
    3344 6i4f:A (1.5) BS01 ATP 3.6.4.- GO:0005200 ... Q8I4X0 31199804
    3345 6i4g:A (2.0) BS01 ATP 3.6.4.- GO:0005200 ... Q8I4X0 31199804
    3346 6i4g:B (2.0) BS01 ATP 3.6.4.- GO:0005200 ... Q8I4X0 31199804
    3347 6i4h:A (1.4) BS01 ATP 3.6.4.- GO:0005200 ... Q8I4X0 31199804
    3348 6i4k:A (1.83) BS01 ATP 3.6.4.- GO:0005200 ... Q8I4X0 31199804
    3349 6i4l:A (1.83) BS01 ATP 3.6.4.- GO:0005200 ... Q8I4X0 31199804
    3350 6i7g:A (2.7) BS01 ATP 2.7.7.108
    3.1.4.-
    N/A Q9BVA6 31531998
    3351 6i7g:B (2.7) BS01 ATP 2.7.7.108
    3.1.4.-
    N/A Q9BVA6 31531998
    3352 6i7i:A (2.33) BS01 ATP 2.7.7.108
    3.1.4.-
    N/A Q9BVA6 31531998
    3353 6i7k:A (2.54) BS01 ATP 2.7.7.108
    3.1.4.-
    N/A Q9BVA6 31531998
    3354 6i8v:A (1.991) BS01 ATP ? GO:0005886 ... P39760 30753894
    3355 6icz:Q (3.0) BS01 ATP 3.6.4.13 GO:0000398 ... O60306 30728453
    3356 6ieh:B (2.892) BS01 ATP 3.6.4.13 GO:0000176 ... P42285 30842217
    3357 6ifr:A (3.4) BS02 ATP N/A N/A N/A 30503210
    3358 6ifr:A (3.4) BS03 ATP N/A N/A N/A 30503210
    3359 6ifr:B (3.4) BS03 ATP N/A N/A N/A 30503210
    3360 6ig0:A (3.37) BS04 ATP N/A N/A N/A 30503210
    3361 6ig0:A (3.37) BS05 ATP N/A N/A N/A 30503210
    3362 6ils:A (1.8) BS01 ATP 2.7.1.15 GO:0004747 ... A1A6H3 30822455
    3363 6ils:B (1.8) BS01 ATP 2.7.1.15 GO:0004747 ... A1A6H3 30822455
    3364 6ilt:A (2.2) BS01 ATP 2.7.1.15 GO:0004747 ... A1A6H3 30822455
    3365 6ilt:B (2.2) BS01 ATP 2.7.1.15 GO:0004747 ... A1A6H3 30822455
    3366 6imj:A (2.554) BS03 ATP 6.5.1.1 GO:0003909 ... P35970 30674878
    3367 6imj:B (2.554) BS03 ATP 6.5.1.1 GO:0003909 ... P35970 30674878
    3368 6ip2:A (3.7) BS01 ATP 3.6.4.6 GO:0000149 ... P18708 30989110
    3369 6ip2:A (3.7) BS02 ATP 3.6.4.6 GO:0000149 ... P18708 30989110
    3370 6ip2:B (3.7) BS01 ATP 3.6.4.6 GO:0000149 ... P18708 30989110
    3371 6ip2:B (3.7) BS02 ATP 3.6.4.6 GO:0000149 ... P18708 30989110
    3372 6ip2:B (3.7) BS03 ATP 3.6.4.6 GO:0000149 ... P18708 30989110
    3373 6ip2:C (3.7) BS01 ATP 3.6.4.6 GO:0000149 ... P18708 30989110
    3374 6ip2:C (3.7) BS02 ATP 3.6.4.6 GO:0000149 ... P18708 30989110
    3375 6ip2:C (3.7) BS03 ATP 3.6.4.6 GO:0000149 ... P18708 30989110
    3376 6ip2:D (3.7) BS01 ATP 3.6.4.6 GO:0000149 ... P18708 30989110
    3377 6ip2:D (3.7) BS02 ATP 3.6.4.6 GO:0000149 ... P18708 30989110
    3378 6ip2:D (3.7) BS03 ATP 3.6.4.6 GO:0000149 ... P18708 30989110
    3379 6ip2:E (3.7) BS01 ATP 3.6.4.6 GO:0000149 ... P18708 30989110
    3380 6ip2:E (3.7) BS02 ATP 3.6.4.6 GO:0000149 ... P18708 30989110
    3381 6ip2:F (3.7) BS01 ATP 3.6.4.6 GO:0000149 ... P18708 30989110
    3382 6ip2:F (3.7) BS02 ATP 3.6.4.6 GO:0000149 ... P18708 30989110
    3383 6iqw:A (3.35) BS01 ATP 2.7.7.-
    3.1.-.-
    GO:0004519 ... B6YWB8 30459428
    3384 6iub:A (1.902) BS01 ATP ? GO:0005524 ... O25759 30544248
    3385 6iub:A (1.902) BS02 ATP ? GO:0005524 ... O25759 30544248
    3386 6iub:B (1.902) BS01 ATP ? GO:0005524 ... O25759 30544248
    3387 6iub:B (1.902) BS02 ATP ? GO:0005524 ... O25759 30544248
    3388 6iuc:A (3.4) BS03 ATP ? GO:0005524 ... O25759 30544248
    3389 6iuc:A (3.4) BS04 ATP ? GO:0005524 ... O25759 30544248
    3390 6iuc:B (3.4) BS02 ATP ? GO:0005524 ... O25759 30544248
    3391 6iuc:B (3.4) BS03 ATP ? GO:0005524 ... O25759 30544248
    3392 6iuc:C (3.4) BS03 ATP ? GO:0005524 ... O25759 30544248
    3393 6iuc:C (3.4) BS05 ATP ? GO:0005524 ... O25759 30544248
    3394 6iuc:D (3.4) BS03 ATP ? GO:0005524 ... O25759 30544248
    3395 6iuc:D (3.4) BS04 ATP ? GO:0005524 ... O25759 30544248
    3396 6j17:A (1.975) BS01 ATP ? N/A P9WNA9 31758528
    3397 6j18:A (2.0) BS01 ATP ? GO:0000166 ... P9WNA5 31758528
    3398 6j19:A (1.978) BS02 ATP ? GO:0000166 ... P9WNB1 31758528
    3399 6j5i:A (3.34) BS01 ATP ? GO:0005524 ... P80021 31197009
    3400 6j5i:B (3.34) BS01 ATP ? GO:0005524 ... P80021 31197009

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218