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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
Download all results in tab-seperated text for 9664 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    3001 6ah4:B (3.296) BS02 ATP ? GO:0001614 ... P56373 31232692 BindingDB: EC50=340nM
    3002 6ah4:B (3.296) BS03 ATP ? GO:0001614 ... P56373 31232692 BindingDB: EC50=340nM
    3003 6ah4:C (3.296) BS02 ATP ? GO:0001614 ... P56373 31232692 BindingDB: EC50=340nM
    3004 6ah4:C (3.296) BS03 ATP ? GO:0001614 ... P56373 31232692 BindingDB: EC50=340nM
    3005 6ah5:A (3.819) BS01 ATP ? GO:0001614 ... P56373 31232692 BindingDB: EC50=340nM
    3006 6ah5:A (3.819) BS02 ATP ? GO:0001614 ... P56373 31232692 BindingDB: EC50=340nM
    3007 6ah5:B (3.819) BS01 ATP ? GO:0001614 ... P56373 31232692 BindingDB: EC50=340nM
    3008 6ah5:B (3.819) BS02 ATP ? GO:0001614 ... P56373 31232692 BindingDB: EC50=340nM
    3009 6ah5:C (3.819) BS02 ATP ? GO:0001614 ... P56373 31232692 BindingDB: EC50=340nM
    3010 6ah5:C (3.819) BS03 ATP ? GO:0001614 ... P56373 31232692 BindingDB: EC50=340nM
    3011 6aqe:A (1.805) BS01 ATP ? GO:0005524 ... Q9RY20 N/A
    3012 6aqe:A (1.805) BS02 ATP ? GO:0005524 ... Q9RY20 N/A
    3013 6aqe:A (1.805) BS03 ATP ? GO:0005524 ... Q9RY20 N/A
    3014 6aqe:B (1.805) BS01 ATP ? GO:0005524 ... Q9RY20 N/A
    3015 6aqe:B (1.805) BS02 ATP ? GO:0005524 ... Q9RY20 N/A
    3016 6aqe:B (1.805) BS03 ATP ? GO:0005524 ... Q9RY20 N/A
    3017 6asi:A (1.789) BS01 ATP 4.1.1.49 GO:0000287 ... P22259 30376300
    3018 6asm:A (1.55) BS01 ATP 4.1.1.49 GO:0000287 ... P22259 30376300
    3019 6asy:A (1.85) BS01 ATP 3.6.4.10 GO:0005509 ... P11021 29084938
    3020 6asy:B (1.85) BS01 ATP 3.6.4.10 GO:0005509 ... P11021 29084938
    3021 6at2:A (1.444) BS01 ATP 4.1.1.49 GO:0000287 ... P22259 30376300
    3022 6awg:A (2.4) BS01 ATP 2.7.1.33 GO:0004594 ... Q2FWC7 N/A
    3023 6awg:C (2.4) BS01 ATP 2.7.1.33 GO:0004594 ... Q2FWC7 N/A
    3024 6awh:A (1.9) BS01 ATP 2.7.1.33 GO:0004594 ... Q2FWC7 N/A
    3025 6awh:B (1.9) BS01 ATP 2.7.1.33 GO:0004594 ... Q2FWC7 N/A
    3026 6awh:C (1.9) BS01 ATP 2.7.1.33 GO:0004594 ... Q2FWC7 N/A
    3027 6awh:D (1.9) BS01 ATP 2.7.1.33 GO:0004594 ... Q2FWC7 N/A
    3028 6az0:A (3.4) BS01 ATP ? GO:0004176 ... B3LL85 29097521
    3029 6az0:B (3.4) BS01 ATP ? GO:0004176 ... B3LL85 29097521
    3030 6az0:C (3.4) BS02 ATP ? GO:0004176 ... B3LL85 29097521
    3031 6az0:D (3.4) BS02 ATP ? GO:0004176 ... B3LL85 29097521
    3032 6az0:D (3.4) BS04 ATP ? GO:0004176 ... B3LL85 29097521
    3033 6baa:A (3.63) BS01 ATP ? GO:0001508 ... P70673 29035201
    3034 6baa:A (3.63) BS02 ATP ? GO:0001508 ... P70673 29035201
    3035 6baa:B (3.63) BS01 ATP ? GO:0001508 ... P70673 29035201
    3036 6baa:B (3.63) BS02 ATP ? GO:0001508 ... P70673 29035201
    3037 6baa:C (3.63) BS01 ATP ? GO:0001508 ... P70673 29035201
    3038 6baa:C (3.63) BS02 ATP ? GO:0001508 ... P70673 29035201
    3039 6baa:D (3.63) BS01 ATP ? GO:0001508 ... P70673 29035201
    3040 6baa:D (3.63) BS02 ATP ? GO:0001508 ... P70673 29035201
    3041 6bco:A (2.88) BS01 ATP ? GO:0002250 ... Q7TN37 29211714
    3042 6bco:A (2.88) BS02 ATP ? GO:0002250 ... Q7TN37 29211714
    3043 6bco:B (2.88) BS01 ATP ? GO:0002250 ... Q7TN37 29211714
    3044 6bco:B (2.88) BS02 ATP ? GO:0002250 ... Q7TN37 29211714
    3045 6bco:C (2.88) BS01 ATP ? GO:0002250 ... Q7TN37 29211714
    3046 6bco:C (2.88) BS02 ATP ? GO:0002250 ... Q7TN37 29211714
    3047 6bco:D (2.88) BS01 ATP ? GO:0002250 ... Q7TN37 29211714
    3048 6bco:D (2.88) BS02 ATP ? GO:0002250 ... Q7TN37 29211714
    3049 6bcq:A (3.25) BS01 ATP ? GO:0002250 ... Q7TN37 29211714
    3050 6bcq:A (3.25) BS02 ATP ? GO:0002250 ... Q7TN37 29211714
    3051 6bcq:B (3.25) BS01 ATP ? GO:0002250 ... Q7TN37 29211714
    3052 6bcq:B (3.25) BS02 ATP ? GO:0002250 ... Q7TN37 29211714
    3053 6bcq:C (3.25) BS01 ATP ? GO:0002250 ... Q7TN37 29211714
    3054 6bcq:C (3.25) BS02 ATP ? GO:0002250 ... Q7TN37 29211714
    3055 6bcq:D (3.25) BS01 ATP ? GO:0002250 ... Q7TN37 29211714
    3056 6bcq:D (3.25) BS02 ATP ? GO:0002250 ... Q7TN37 29211714
    3057 6bcu:A (3.8) BS01 ATP 2.7.11.1 GO:0000139 ... P42345 29236692
    3058 6bcu:B (3.8) BS01 ATP 2.7.11.1 GO:0000139 ... P42345 29236692
    3059 6bcx:A (3.23) BS01 ATP 2.7.11.1 GO:0000139 ... P42345 29236692
    3060 6bcx:B (3.23) BS01 ATP 2.7.11.1 GO:0000139 ... P42345 29236692
    3061 6bhu:A (3.14) BS01 ATP 7.6.2.2
    7.6.2.3
    GO:0005524 ... Q8HXQ5 29290467
    3062 6bhu:A (3.14) BS02 ATP 7.6.2.2
    7.6.2.3
    GO:0005524 ... Q8HXQ5 29290467
    3063 6blk:A (1.552) BS01 ATP 2.7.13.3 GO:0016310 ... K5BDW2 N/A
    3064 6blk:B (1.552) BS01 ATP 2.7.13.3 GO:0016310 ... K5BDW2 N/A
    3065 6blk:C (1.552) BS01 ATP 2.7.13.3 GO:0016310 ... K5BDW2 N/A
    3066 6blk:D (1.552) BS01 ATP 2.7.13.3 GO:0016310 ... K5BDW2 N/A
    3067 6byr:A (3.661) BS01 ATP 2.7.11.11 GO:0000287 ... P17612
    P25685
    30905674
    3068 6byr:C (3.661) BS01 ATP 2.7.11.11 GO:0000287 ... P17612
    P25685
    30905674
    3069 6c0v:A (3.4) BS01 ATP 7.6.2.1
    7.6.2.2
    GO:0000086 ... P08183 29371429
    3070 6c0v:A (3.4) BS02 ATP 7.6.2.1
    7.6.2.2
    GO:0000086 ... P08183 29371429
    3071 6c3o:A (3.9) BS01 ATP ? GO:0001508 ... Q14654 29286281
    3072 6c3o:A (3.9) BS02 ATP ? GO:0001508 ... Q14654 29286281
    3073 6c3o:B (3.9) BS01 ATP ? GO:0001508 ... Q14654 29286281
    3074 6c3o:B (3.9) BS02 ATP ? GO:0001508 ... Q14654 29286281
    3075 6c3o:C (3.9) BS01 ATP ? GO:0001508 ... Q14654 29286281
    3076 6c3o:C (3.9) BS02 ATP ? GO:0001508 ... Q14654 29286281
    3077 6c3o:D (3.9) BS01 ATP ? GO:0001508 ... Q14654 29286281
    3078 6c3o:D (3.9) BS02 ATP ? GO:0001508 ... Q14654 29286281
    3079 6c3o:E (3.9) BS03 ATP ? GO:0001508 ... Q09428 29286281
    3080 6c3o:F (3.9) BS03 ATP ? GO:0001508 ... Q09428 29286281
    3081 6c3o:G (3.9) BS03 ATP ? GO:0001508 ... Q09428 29286281
    3082 6c3o:H (3.9) BS03 ATP ? GO:0001508 ... Q09428 29286281
    3083 6c3p:A (5.6) BS01 ATP ? GO:0001508 ... Q14654 29286281
    3084 6c3p:A (5.6) BS02 ATP ? GO:0001508 ... Q14654 29286281
    3085 6c3p:B (5.6) BS01 ATP ? GO:0001508 ... Q14654 29286281
    3086 6c3p:B (5.6) BS02 ATP ? GO:0001508 ... Q14654 29286281
    3087 6c3p:C (5.6) BS01 ATP ? GO:0001508 ... Q14654 29286281
    3088 6c3p:C (5.6) BS02 ATP ? GO:0001508 ... Q14654 29286281
    3089 6c3p:D (5.6) BS01 ATP ? GO:0001508 ... Q14654 29286281
    3090 6c3p:D (5.6) BS02 ATP ? GO:0001508 ... Q14654 29286281
    3091 6c3p:E (5.6) BS03 ATP ? GO:0001508 ... Q09428 29286281
    3092 6c3p:F (5.6) BS03 ATP ? GO:0001508 ... Q09428 29286281
    3093 6c3p:G (5.6) BS03 ATP ? GO:0001508 ... Q09428 29286281
    3094 6c3p:H (5.6) BS03 ATP ? GO:0001508 ... Q09428 29286281
    3095 6cck:A (1.61) BS02 ATP 2.7.7.3 GO:0003824 ... P0A6I6 29498517
    3096 6cck:B (1.61) BS02 ATP 2.7.7.3 GO:0003824 ... P0A6I6 29498517
    3097 6cmw:A (3.15) BS01 ATP 2.7.1.68 GO:0046488 ... Q503I3 29959184
    3098 6cn2:A (3.102) BS01 ATP 2.7.1.68 GO:0046488 ... Q503I3 29959184
    3099 6com:A (2.3) BS01 ATP 4.1.1.49 GO:0000287 ... P22259 31911238
    3100 6cp3:A (3.8) BS01 ATP ? GO:0005524 ... P07251 29650704
    3101 6cp3:B (3.8) BS01 ATP ? GO:0005524 ... P07251 29650704
    3102 6cp3:C (3.8) BS01 ATP ? GO:0005524 ... P07251 29650704
    3103 6cp6:A (3.6) BS01 ATP ? GO:0005524 ... P07251 29650704
    3104 6cp6:B (3.6) BS01 ATP ? GO:0005524 ... P07251 29650704
    3105 6cp6:C (3.6) BS01 ATP ? GO:0005524 ... P07251 29650704
    3106 6crt:A (1.995) BS01 ATP 4.1.1.49 GO:0000287 ... P22259 N/A
    3107 6cta:A (2.779) BS05 ATP 2.7.7.86 N/A Q8N884 30007416
    3108 6cvv:A (2.41) BS01 ATP 6.3.3.3 GO:0000287 ... P9WPQ5 N/A PDBbind: -logKd/Ki=4.12, Kd=75uM
    3109 6cvv:B (2.41) BS01 ATP 6.3.3.3 GO:0000287 ... P9WPQ5 N/A PDBbind: -logKd/Ki=4.12, Kd=75uM
    3110 6cvv:C (2.41) BS01 ATP 6.3.3.3 GO:0000287 ... P9WPQ5 N/A
    3111 6cvv:D (2.41) BS01 ATP 6.3.3.3 GO:0000287 ... P9WPQ5 N/A
    3112 6d3r:A (4.3) BS01 ATP N/A GO:0005254 ... N/A 30281975
    3113 6d3r:A (4.3) BS02 ATP N/A GO:0005254 ... N/A 30281975
    3114 6d3s:A (6.6) BS01 ATP 5.6.1.6 GO:0005254 ... A0M8U4 30281975
    3115 6d3s:A (6.6) BS02 ATP 5.6.1.6 GO:0005254 ... A0M8U4 30281975
    3116 6d5k:B (2.85) BS02 ATP 2.5.1.- N/A Q96EY8 30282455
    3117 6d5k:C (2.85) BS02 ATP 2.5.1.- N/A Q96EY8 30282455
    3118 6d5x:B (2.4) BS02 ATP 2.5.1.- N/A Q96EY8 30282455
    3119 6d5x:C (2.4) BS03 ATP 2.5.1.- N/A Q96EY8 30282455
    3120 6ddz:A (1.97) BS01 ATP 2.7.1.77
    3.1.3.5
    3.1.3.99
    GO:0000255 ... P49902 29990496
    3121 6de2:A (2.1) BS01 ATP 2.7.1.77
    3.1.3.5
    3.1.3.99
    GO:0000255 ... P49902 29990496
    3122 6de3:A (3.06) BS01 ATP 2.7.1.77
    3.1.3.5
    3.1.3.99
    GO:0000255 ... P49902 29990496
    3123 6dec:A (4.6) BS01 ATP ? GO:0003779 ... P61157 30322896
    3124 6dec:B (4.6) BS01 ATP ? GO:0003779 ... A7MB62 30322896
    3125 6dec:H (4.6) BS01 ATP ? GO:0003779 ... P61157 30322896
    3126 6dec:I (4.6) BS01 ATP ? GO:0003779 ... A7MB62 30322896
    3127 6ech:A (2.19) BS04 ATP 2.7.1.40 GO:0000287 ... P12928 31825824
    3128 6ech:B (2.19) BS04 ATP 2.7.1.40 GO:0000287 ... P12928 31825824
    3129 6ech:D (2.19) BS04 ATP 2.7.1.40 GO:0000287 ... P12928 31825824
    3130 6ef0:I (4.43) BS02 ATP ? GO:0005524 ... P40327 30309908
    3131 6ef0:J (4.43) BS01 ATP ? GO:0005524 ... Q01939 30309908
    3132 6ef0:J (4.43) BS02 ATP ? GO:0005524 ... Q01939 30309908
    3133 6ef0:K (4.43) BS01 ATP ? GO:0005524 ... P33298 30309908
    3134 6ef0:K (4.43) BS02 ATP ? GO:0005524 ... P33298 30309908
    3135 6ef0:L (4.43) BS02 ATP ? GO:0005524 ... P53549 30309908
    3136 6ef1:H (4.73) BS01 ATP ? GO:0005524 ... P33299 30309908
    3137 6ef1:I (4.73) BS01 ATP ? GO:0005524 ... P40327 30309908
    3138 6ef1:J (4.73) BS01 ATP ? GO:0005524 ... Q01939 30309908
    3139 6ef1:J (4.73) BS02 ATP ? GO:0005524 ... Q01939 30309908
    3140 6ef1:K (4.73) BS02 ATP ? GO:0005524 ... P33298 30309908
    3141 6ef2:H (4.27) BS01 ATP ? GO:0005524 ... P33299 30309908
    3142 6ef2:I (4.27) BS02 ATP ? GO:0005524 ... P40327 30309908
    3143 6ef2:I (4.27) BS03 ATP ? GO:0005524 ... P40327 30309908
    3144 6ef2:J (4.27) BS01 ATP ? GO:0005524 ... Q01939 30309908
    3145 6ef2:M (4.27) BS01 ATP ? GO:0005524 ... P33297 30309908
    3146 6ef3:H (4.17) BS01 ATP ? GO:0000502 ... P33299 30309908
    3147 6ef3:I (4.17) BS01 ATP ? GO:0000502 ... P40327 30309908
    3148 6ef3:I (4.17) BS02 ATP ? GO:0000502 ... P40327 30309908
    3149 6ef3:J (4.17) BS01 ATP ? GO:0000502 ... Q01939 30309908
    3150 6ef3:M (4.17) BS01 ATP ? GO:0000502 ... P33297 30309908
    3151 6ema:A (1.88) BS02 ATP 2.7.11.11 GO:0000287 ... P25321 N/A
    3152 6f1t:H (3.5) BS01 ATP 3.6.4.- GO:0005515 ... Q6QAQ1 29420470
    3153 6f38:H (6.7) BS01 ATP 3.6.4.- GO:0005515 ... Q6QAQ1 29420470
    3154 6f3a:H (8.2) BS01 ATP 3.6.4.- GO:0005515 ... Q6QAQ1 29420470
    3155 6fct:A (1.89) BS02 ATP 2.4.2.17 GO:0000105 ... Q4FQF7 N/A
    3156 6fhs:J (3.754) BS01 ATP ? N/A G0S589 29643509
    3157 6fkf:A (3.15) BS01 ATP 7.1.2.2 GO:0005524 ... P06450 29748256
    3158 6fkf:C (3.15) BS01 ATP 7.1.2.2 GO:0005524 ... P06450 29748256
    3159 6fkf:E (3.15) BS01 ATP 7.1.2.2 GO:0005524 ... P06450 29748256
    3160 6fkh:A (4.2) BS01 ATP 7.1.2.2 GO:0005524 ... P06450 29748256
    3161 6fkh:C (4.2) BS01 ATP 7.1.2.2 GO:0005524 ... P06450 29748256
    3162 6fkh:E (4.2) BS01 ATP 7.1.2.2 GO:0005524 ... P06450 29748256
    3163 6fki:A (4.3) BS01 ATP 7.1.2.2 GO:0005524 ... P06450 29748256
    3164 6fki:C (4.3) BS01 ATP 7.1.2.2 GO:0005524 ... P06450 29748256
    3165 6fki:E (4.3) BS01 ATP 7.1.2.2 GO:0005524 ... P06450 29748256
    3166 6fko:A (2.1) BS03 ATP 6.3.4.25 GO:0000166 ... G3FFN6 N/A
    3167 6fko:B (2.1) BS02 ATP 6.3.4.25 GO:0000166 ... G3FFN6 N/A
    3168 6fm0:A (1.7) BS01 ATP 6.3.4.25 GO:0000166 ... G3FFN6 33926955
    3169 6fm0:B (1.7) BS01 ATP 6.3.4.25 GO:0000166 ... G3FFN6 33926955
    3170 6fm1:A (2.35) BS01 ATP 6.3.4.25 GO:0000166 ... G3FFN6 33926955
    3171 6fm1:B (2.35) BS01 ATP 6.3.4.25 GO:0000166 ... G3FFN6 33926955
    3172 6fml:J (4.34) BS02 ATP ? N/A G0S589 29643509
    3173 6fu2:C (2.71) BS02 ATP 2.4.2.17 GO:0000105 ... Q4FQF7 N/A
    3174 6fu2:D (2.71) BS02 ATP 2.4.2.17 GO:0000105 ... Q4FQF7 N/A
    3175 6fvf:A (1.47) BS02 ATP 2.7.11.1 GO:0004672 ... P68400 31685885
    3176 6fvg:A (1.6) BS02 ATP 2.7.11.1 GO:0004672 ... P68400 31685885
    3177 6fvt:H (4.1) BS01 ATP ? GO:0000502 ... P33299 30067984
    3178 6fvt:H (4.1) BS02 ATP ? GO:0000502 ... P33299 30067984
    3179 6fvt:I (4.1) BS01 ATP ? GO:0005524 ... P40327 30067984
    3180 6fvt:I (4.1) BS02 ATP ? GO:0005524 ... P40327 30067984
    3181 6fvt:K (4.1) BS01 ATP ? GO:0000502 ... P33298 30067984
    3182 6fvt:L (4.1) BS01 ATP ? GO:0005524 ... P53549 30067984
    3183 6fvt:L (4.1) BS02 ATP ? GO:0005524 ... P53549 30067984
    3184 6fvt:M (4.1) BS01 ATP ? GO:0000502 ... P33297 30067984
    3185 6fvt:M (4.1) BS02 ATP ? GO:0000502 ... P33297 30067984
    3186 6fvu:H (4.5) BS01 ATP ? GO:0000502 ... P33299 30067984
    3187 6fvu:I (4.5) BS01 ATP ? GO:0005524 ... P40327 30067984
    3188 6fvu:J (4.5) BS01 ATP ? GO:0000502 ... Q01939 30067984
    3189 6fvu:K (4.5) BS01 ATP ? GO:0000502 ... P33298 30067984
    3190 6fvu:L (4.5) BS01 ATP ? GO:0005524 ... P53549 30067984
    3191 6fvu:L (4.5) BS02 ATP ? GO:0005524 ... P53549 30067984
    3192 6fvu:M (4.5) BS01 ATP ? GO:0000502 ... P33297 30067984
    3193 6fvu:M (4.5) BS02 ATP ? GO:0000502 ... P33297 30067984
    3194 6fvv:I (5.4) BS01 ATP ? GO:0005524 ... P40327 30067984
    3195 6fvv:J (5.4) BS01 ATP ? GO:0000502 ... Q01939 30067984
    3196 6fvv:K (5.4) BS01 ATP ? GO:0000502 ... P33298 30067984
    3197 6fvv:L (5.4) BS01 ATP ? GO:0005524 ... P53549 30067984
    3198 6fvw:H (4.5) BS01 ATP ? GO:0000502 ... P33299 30067984
    3199 6fvw:I (4.5) BS01 ATP ? GO:0005524 ... P40327 30067984
    3200 6fvw:I (4.5) BS02 ATP ? GO:0005524 ... P40327 30067984

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218