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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
Download all results in tab-seperated text for 581 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    201 3cev:D (2.4) BS03 ARG 3.5.3.1 GO:0000050 ... P53608 10196128
    202 3cev:E (2.4) BS02 ARG 3.5.3.1 GO:0000050 ... P53608 10196128
    203 3cev:E (2.4) BS03 ARG 3.5.3.1 GO:0000050 ... P53608 10196128
    204 3cev:F (2.4) BS01 ARG 3.5.3.1 GO:0000050 ... P53608 10196128
    205 3cev:F (2.4) BS03 ARG 3.5.3.1 GO:0000050 ... P53608 10196128
    206 3cev:F (2.4) BS04 ARG 3.5.3.1 GO:0000050 ... P53608 10196128
    207 3d2p:A (2.56) BS02 ARG 2.3.1.1 GO:0004042 ... Q5FAK7 19095660
    208 3d2p:B (2.56) BS02 ARG 2.3.1.1 GO:0004042 ... Q5FAK7 19095660
    209 3d68:A (2.8) BS02 ARG 3.4.17.20 GO:0003331 ... Q96IY4 18559974
    210 3d68:B (2.8) BS02 ARG 3.4.17.20 GO:0003331 ... Q96IY4 18559974
    211 3d68:C (2.8) BS02 ARG 3.4.17.20 GO:0003331 ... Q96IY4 18559974
    212 3dug:A (2.62) BS05 ARG N/A GO:0016787 ... N/A 19281183
    213 3dug:B (2.62) BS05 ARG N/A GO:0016787 ... N/A 19281183
    214 3dug:C (2.62) BS05 ARG N/A GO:0016787 ... N/A 19281183
    215 3dug:D (2.62) BS04 ARG N/A GO:0016787 ... N/A 19281183
    216 3dug:E (2.62) BS05 ARG N/A GO:0016787 ... N/A 19281183
    217 3dug:F (2.62) BS05 ARG N/A GO:0016787 ... N/A 19281183
    218 3dug:G (2.62) BS05 ARG N/A GO:0016787 ... N/A 19281183
    219 3dug:H (2.62) BS05 ARG N/A GO:0016787 ... N/A 19281183
    220 3ems:A (1.651) BS01 ARG 3.2.1.17 GO:0003796 ... P00698 N/A
    221 3ems:A (1.651) BS02 ARG 3.2.1.17 GO:0003796 ... P00698 N/A
    222 3ems:A (1.651) BS03 ARG 3.2.1.17 GO:0003796 ... P00698 N/A
    223 3ems:A (1.651) BS04 ARG 3.2.1.17 GO:0003796 ... P00698 N/A
    224 3fc5:A (2.59) BS04 ARG 1.14.13.39 GO:0004517 ... P29476 N/A
    225 3fc5:B (2.59) BS05 ARG 1.14.13.39 GO:0004517 ... P29476 N/A
    226 3fhz:A (3.27) BS03 ARG ? GO:0003677 ... P9WPY9 19265706
    227 3fhz:A (3.27) BS04 ARG ? GO:0003677 ... P9WPY9 19265706
    228 3fhz:B (3.27) BS03 ARG ? GO:0003677 ... P9WPY9 19265706
    229 3fhz:B (3.27) BS04 ARG ? GO:0003677 ... P9WPY9 19265706
    230 3fhz:B (3.27) BS05 ARG ? GO:0003677 ... P9WPY9 19265706
    231 3fhz:C (3.27) BS03 ARG ? GO:0003677 ... P9WPY9 19265706
    232 3fhz:C (3.27) BS04 ARG ? GO:0003677 ... P9WPY9 19265706
    233 3fhz:D (3.27) BS03 ARG ? GO:0003677 ... P9WPY9 19265706
    234 3fhz:D (3.27) BS04 ARG ? GO:0003677 ... P9WPY9 19265706
    235 3fhz:E (3.27) BS03 ARG ? GO:0003677 ... P9WPY9 19265706
    236 3fhz:E (3.27) BS04 ARG ? GO:0003677 ... P9WPY9 19265706
    237 3fhz:F (3.27) BS03 ARG ? GO:0003677 ... P9WPY9 19265706
    238 3fhz:F (3.27) BS04 ARG ? GO:0003677 ... P9WPY9 19265706
    239 3ju6:A (2.45) BS01 ARG 2.7.3.3 GO:0003824 ... Q9XY07 19783784
    240 3kum:A (1.9) BS01 ARG 5.1.1.- GO:0000287 ... Q834W6 22392983
    241 3kum:B (1.9) BS01 ARG 5.1.1.- GO:0000287 ... Q834W6 22392983
    242 3kum:C (1.9) BS01 ARG 5.1.1.- GO:0000287 ... Q834W6 22392983
    243 3kum:D (1.9) BS01 ARG 5.1.1.- GO:0000287 ... Q834W6 22392983
    244 3kum:E (1.9) BS01 ARG 5.1.1.- GO:0000287 ... Q834W6 22392983
    245 3kum:F (1.9) BS01 ARG 5.1.1.- GO:0000287 ... Q834W6 22392983
    246 3kum:G (1.9) BS01 ARG 5.1.1.- GO:0000287 ... Q834W6 22392983
    247 3kum:H (1.9) BS01 ARG 5.1.1.- GO:0000287 ... Q834W6 22392983
    248 3l1l:A (3.002) BS01 ARG ? GO:0005886 ... P60063 20090677
    249 3laj:A (2.306) BS03 ARG ? GO:0003677 ... P9WPY9 20382162
    250 3laj:A (2.306) BS04 ARG ? GO:0003677 ... P9WPY9 20382162
    251 3laj:B (2.306) BS03 ARG ? GO:0003677 ... P9WPY9 20382162
    252 3laj:B (2.306) BS04 ARG ? GO:0003677 ... P9WPY9 20382162
    253 3laj:C (2.306) BS03 ARG ? GO:0003677 ... P9WPY9 20382162
    254 3laj:C (2.306) BS04 ARG ? GO:0003677 ... P9WPY9 20382162
    255 3laj:D (2.306) BS03 ARG ? GO:0003677 ... P9WPY9 20382162
    256 3laj:D (2.306) BS04 ARG ? GO:0003677 ... P9WPY9 20382162
    257 3laj:E (2.306) BS03 ARG ? GO:0003677 ... P9WPY9 20382162
    258 3laj:E (2.306) BS04 ARG ? GO:0003677 ... P9WPY9 20382162
    259 3laj:F (2.306) BS03 ARG ? GO:0003677 ... P9WPY9 20382162
    260 3laj:F (2.306) BS04 ARG ? GO:0003677 ... P9WPY9 20382162
    261 3lum:A (1.7) BS04 ARG 3.4.24.- GO:0008237 ... Q8TL28 20202937
    262 3lum:B (1.7) BS04 ARG 3.4.24.- GO:0008237 ... Q8TL28 20202937
    263 3lum:C (1.7) BS04 ARG 3.4.24.- GO:0008237 ... Q8TL28 20202937
    264 3lum:D (1.7) BS04 ARG 3.4.24.- GO:0008237 ... Q8TL28 20202937
    265 3lun:B (1.8) BS05 ARG 3.4.24.- GO:0008237 ... Q8TL28 20202937
    266 3mff:D (2.0) BS01 ARG N/A N/A N/A 20630474
    267 3n26:A (2.1) BS01 ARG ? N/A Q9Z869 20592031
    268 3nse:A (2.1) BS01 ARG 1.14.13.39 GO:0004517 ... P29473 9875848
    269 3nse:B (2.1) BS01 ARG 1.14.13.39 GO:0004517 ... P29473 9875848
    270 3ob6:A (3.0) BS01 ARG ? GO:0003333 ... P60061 21368142
    271 3ob6:B (3.0) BS01 ARG ? GO:0003333 ... P60061 21368142
    272 3qax:A (2.0) BS01 ARG ? N/A Q9Z869 N/A
    273 3qax:B (2.0) BS01 ARG ? N/A Q9Z869 N/A
    274 3rit:A (2.701) BS01 ARG 5.1.1.- GO:0000287 ... Q607C7 22392983
    275 3rit:B (2.701) BS01 ARG 5.1.1.- GO:0000287 ... Q607C7 22392983
    276 3rit:C (2.701) BS01 ARG 5.1.1.- GO:0000287 ... Q607C7 22392983
    277 3rit:D (2.701) BS01 ARG 5.1.1.- GO:0000287 ... Q607C7 22392983
    278 3rit:E (2.701) BS01 ARG 5.1.1.- GO:0000287 ... Q607C7 22392983
    279 3tql:A (1.594) BS01 ARG ? GO:0015276 ... Q83E49 26033498
    280 3u9e:B (2.04) BS04 ARG ? GO:0016746 ... Q8Y7B7 N/A
    281 3vvf:A (1.9) BS01 ARG ? GO:0015276 ... Q72JG5 23794618
    282 3vvf:B (1.9) BS01 ARG ? GO:0015276 ... Q72JG5 23794618
    283 3w5f:A (1.65) BS01 ARG 3.2.1.23 GO:0004553 ... O81100 N/A
    284 3zzh:C (2.1) BS01 ARG 1.2.1.38
    2.7.2.8
    GO:0005737 ... Q01217 22529931 PDBbind: -logKd/Ki=3.36, IC50=0.44mM
    285 4b66:A (2.9) BS01 ARG 1.14.13.196 GO:0000166 ... E9QYP0 22928747
    286 4b68:A (2.29) BS01 ARG 1.14.13.196 GO:0000166 ... E9QYP0 22928747
    287 4ba0:A (1.85) BS01 ARG 2.4.1.161 GO:0003824 ... B3PEE6 23132856
    288 4bg4:A (1.601) BS02 ARG 2.7.3.3 GO:0003824 ... Q004B5 23873077
    289 4bg4:B (1.601) BS02 ARG 2.7.3.3 GO:0003824 ... Q004B5 23873077
    290 4bhl:A (1.9) BS01 ARG 2.7.3.3 GO:0003824 ... Q004B5 23873077
    291 4bkt:I (2.35) BS01 ARG ? N/A P40337 24436777
    292 4bl6:C (2.18) BS01 ARG ? GO:0008093 ... P16568 23723415
    293 4cul:A (2.23) BS01 ARG 1.14.13.39 GO:0004517 ... P29473 24819538
    294 4cul:B (2.23) BS02 ARG 1.14.13.39 GO:0004517 ... P29473 24819538
    295 4cum:A (2.33) BS01 ARG 1.14.13.39 GO:0004517 ... P29473 24819538
    296 4cum:B (2.33) BS03 ARG 1.14.13.39 GO:0004517 ... P29473 24819538
    297 4cun:A (2.48) BS01 ARG 1.14.13.39 GO:0004517 ... P29473 24819538
    298 4cun:B (2.48) BS03 ARG 1.14.13.39 GO:0004517 ... P29473 24819538
    299 4cvg:A (2.31) BS01 ARG 1.14.13.39 GO:0004517 ... P29473 24819538
    300 4cvg:B (2.31) BS02 ARG 1.14.13.39 GO:0004517 ... P29473 24819538
    301 4d1n:A (2.03) BS01 ARG 1.14.13.39 GO:0004517 ... P29475 25286850
    302 4d1n:B (2.03) BS03 ARG 1.14.13.39 GO:0004517 ... P29475 25286850
    303 4d1n:C (2.03) BS01 ARG 1.14.13.39 GO:0004517 ... P29475 25286850
    304 4d1n:D (2.03) BS03 ARG 1.14.13.39 GO:0004517 ... P29475 25286850
    305 4d1o:A (1.819) BS01 ARG 1.14.13.39 GO:0004517 ... P29474 25286850
    306 4d1o:B (1.819) BS03 ARG 1.14.13.39 GO:0004517 ... P29474 25286850
    307 4d49:E (2.09) BS02 ARG N/A N/A N/A 27664438
    308 4d4i:A (2.0) BS01 ARG ? GO:0000166 ... G0WVH3 26096082
    309 4d57:A (2.0) BS01 ARG ? GO:0000166 ... G0WVH3 26096082
    310 4eof:A (1.83) BS01 ARG 3.2.1.17 GO:0003796 ... P00698 26926993
    311 4eof:A (1.83) BS02 ARG 3.2.1.17 GO:0003796 ... P00698 26926993
    312 4gjw:B (3.0) BS01 ARG ? N/A Q9IK91 N/A
    313 4h5f:A (1.9) BS01 ARG N/A GO:0015276 ... N/A N/A
    314 4h5f:B (1.9) BS01 ARG N/A GO:0015276 ... N/A N/A
    315 4h5f:C (1.9) BS01 ARG N/A GO:0015276 ... N/A N/A
    316 4h5f:D (1.9) BS01 ARG N/A GO:0015276 ... N/A N/A
    317 4h5g:A (1.78) BS01 ARG N/A GO:0015276 ... N/A N/A
    318 4h5g:B (1.78) BS01 ARG N/A GO:0015276 ... N/A N/A
    319 4h7o:A (2.17) BS02 ARG 2.3.1.30 GO:0005737 ... Q9KNT2 N/A
    320 4h7o:B (2.17) BS02 ARG 2.3.1.30 GO:0005737 ... Q9KNT2 N/A
    321 4h7o:C (2.17) BS03 ARG 2.3.1.30 GO:0005737 ... Q9KNT2 N/A
    322 4hsf:A (1.82) BS01 ARG 3.2.1.17 GO:0003796 ... P00698 N/A
    323 4hsf:A (1.82) BS02 ARG 3.2.1.17 GO:0003796 ... P00698 N/A
    324 4i62:A (1.05) BS01 ARG ? GO:0015276 ... A0A0H2ZN67 N/A
    325 4j3b:A (2.2) BS01 ARG 3.4.11.- GO:0006508 ... O96935 23897806
    326 4jdw:A (2.5) BS01 ARG 2.1.4.1 GO:0005515 ... P50440 9218780
    327 4jhx:A (1.85) BS02 ARG 2.1.3.3 GO:0004585 ... Q8DCF5 N/A
    328 4kx9:A (2.25) BS02 ARG 3.4.11.7 GO:0001525 ... Q07075 23888046
    329 4kzt:A (2.8) BS01 ARG 2.7.2.8 GO:0003824 ... Q0ASS9 23850694
    330 4kzt:B (2.8) BS01 ARG 2.7.2.8 GO:0003824 ... Q0ASS9 23850694
    331 4kzt:X (2.8) BS01 ARG 2.7.2.8 GO:0003824 ... Q0ASS9 23850694
    332 4kzt:Y (2.8) BS01 ARG 2.7.2.8 GO:0003824 ... Q0ASS9 23850694
    333 4lt4:A (1.69) BS01 ARG 3.2.2.22 GO:0000166 ... D9J2T9 N/A
    334 4m27:C (2.35) BS01 ARG 1.14.11.41 GO:0005506 ... G9MBV2 24505011
    335 4m27:D (2.35) BS01 ARG 1.14.11.41 GO:0005506 ... G9MBV2 24505011
    336 4m2m:A (1.58) BS02 ARG 4.3.2.- GO:0008483 ... G9MBV4 24505011
    337 4nse:A (1.95) BS01 ARG 1.14.13.39 GO:0004517 ... P29473 9875848
    338 4nse:B (1.95) BS02 ARG 1.14.13.39 GO:0004517 ... P29473 9875848
    339 4oby:A (2.574) BS01 ARG 6.1.1.19 GO:0000166 ... P11875 24474195
    340 4psh:A (2.6) BS01 ARG ? GO:0015276 ... Q9WZ62 24832102 PDBbind: -logKd/Ki=8.89, Kd=1.3nM
    341 4psh:B (2.6) BS01 ARG ? GO:0015276 ... Q9WZ62 24832102
    342 4q2t:A (2.4) BS01 ARG 6.1.1.19 GO:0000166 ... P54136 24859084
    343 4q2t:B (2.4) BS01 ARG 6.1.1.19 GO:0000166 ... P54136 24859084
    344 4rf7:A (2.1) BS01 ARG 2.7.3.3 GO:0003824 ... O15992 25849389
    345 4rf7:A (2.1) BS02 ARG 2.7.3.3 GO:0003824 ... O15992 25849389
    346 4rf7:A (2.1) BS03 ARG 2.7.3.3 GO:0003824 ... O15992 25849389
    347 4rf7:B (2.1) BS01 ARG 2.7.3.3 GO:0003824 ... O15992 25849389
    348 4rf7:B (2.1) BS02 ARG 2.7.3.3 GO:0003824 ... O15992 25849389
    349 4rf7:B (2.1) BS03 ARG 2.7.3.3 GO:0003824 ... O15992 25849389
    350 4rf9:A (2.35) BS01 ARG 2.7.3.3 GO:0003824 ... O15992 25849389
    351 4rf9:B (2.35) BS02 ARG 2.7.3.3 GO:0003824 ... O15992 25849389
    352 4ugv:A (1.985) BS03 ARG 1.14.14.47 GO:0004517 ... O34453 26062720
    353 4usj:A (2.85) BS01 ARG 2.7.2.8 GO:0003991 ... Q9SCL7 25416954 PDBbind: -logKd/Ki=4.00, IC50=0.1mM
    354 4usj:B (2.85) BS01 ARG 2.7.2.8 GO:0003991 ... Q9SCL7 25416954 PDBbind: -logKd/Ki=4.00, IC50=0.1mM
    355 4wod:A (1.9) BS01 ARG 2.7.3.4 GO:0003824 ... P16641 25837252
    356 4xfj:A (1.55) BS02 ARG 6.3.4.5 GO:0000050 ... G7CBN9 N/A
    357 4xfj:B (1.55) BS02 ARG 6.3.4.5 GO:0000050 ... G7CBN9 N/A
    358 4xmv:A (2.92) BS02 ARG 3.4.11.2 GO:0004177 ... P04825 N/A
    359 4y4o:1F (2.3) BS16 ARG ? GO:0003735 ... Q5SHN9 25775268
    360 4ymt:B (2.599) BS01 ARG ? GO:0005886 ... Q8RCC3 25848002
    361 4ymt:B (2.599) BS02 ARG ? GO:0005886 ... Q8RCC3 25848002
    362 4ymt:C (2.599) BS01 ARG ? GO:0005886 ... Q8RCC3 25848002
    363 4ymt:C (2.599) BS02 ARG ? GO:0005886 ... Q8RCC3 25848002
    364 4ymu:C (2.503) BS01 ARG ? GO:0005886 ... Q8RCC3 25848002
    365 4ymu:C (2.503) BS02 ARG ? GO:0005886 ... Q8RCC3 25848002
    366 4ymu:D (2.503) BS01 ARG ? GO:0005886 ... Q8RCC3 25848002
    367 4ymu:D (2.503) BS02 ARG ? GO:0005886 ... Q8RCC3 25848002
    368 4ymx:A (1.481) BS01 ARG ? GO:0015276 ... Q8RCC4 25848002 MOAD: Kd=79nM
    PDBbind: -logKd/Ki=7.10, Kd=79nM
    369 4ymx:B (1.481) BS01 ARG ? GO:0015276 ... Q8RCC4 25848002 MOAD: Kd=79nM
    370 4ytg:A (1.8) BS02 ARG 3.5.3.- GO:0004668 ... Q9RQJ2 26132828
    371 4zv1:A (1.52) BS01 ARG N/A GO:0015276 ... N/A 26853627 MOAD: Kd=5.73uM
    PDBbind: -logKd/Ki=5.24, Kd=5.73uM
    372 5ak7:A (1.46) BS01 ARG 3.5.3.- GO:0004668 ... Q9RQJ2 26209657
    373 5ak8:A (1.48) BS01 ARG 3.5.3.- GO:0004668 ... Q9RQJ2 26209657
    374 5ft0:A (2.2) BS01 ARG ? N/A Q8SDC5 27447594
    375 5ft0:B (2.2) BS01 ARG ? N/A Q8SDC5 27447594
    376 5gs9:A (2.5) BS01 ARG ? GO:0005515 ... Q8WTX7 27648300 MOAD: Kd=5.5uM
    PDBbind: -logKd/Ki=5.26, Kd=5.5uM
    377 5gs9:B (2.5) BS01 ARG ? GO:0005515 ... Q8WTX7 27648300 MOAD: Kd=5.5uM
    378 5gs9:C (2.5) BS01 ARG ? GO:0005515 ... Q8WTX7 27648300 MOAD: Kd=5.5uM
    379 5gs9:D (2.5) BS01 ARG ? GO:0005515 ... Q8WTX7 27648300 MOAD: Kd=5.5uM
    380 5gt7:A (2.048) BS01 ARG ? GO:0005515 ... Q8WTX7 30503338
    381 5gt7:B (2.048) BS01 ARG ? GO:0005515 ... Q8WTX7 30503338
    382 5gt7:C (2.048) BS01 ARG ? GO:0005515 ... Q8WTX7 30503338
    383 5gt7:D (2.048) BS01 ARG ? GO:0005515 ... Q8WTX7 30503338
    384 5gv2:A (2.06) BS01 ARG ? GO:0005515 ... Q8WTX7 28066558 PDBbind: -logKd/Ki=5.65, Kd=2.23uM
    385 5gzs:A (2.601) BS01 ARG ? N/A Q9KT38 28500346
    386 5i2c:A (1.801) BS01 ARG ? GO:0005515 ... Q8WTX7 27487210
    387 5i2c:B (1.801) BS01 ARG ? GO:0005515 ... Q8WTX7 27487210
    388 5i2c:C (1.801) BS01 ARG ? GO:0005515 ... Q8WTX7 27487210
    389 5i2c:D (1.801) BS01 ARG ? GO:0005515 ... Q8WTX7 27487210
    390 5j99:A (1.7) BS02 ARG 2.7.3.3 GO:0003824 ... P51541 27594681
    391 5j9a:A (1.997) BS01 ARG 2.7.3.3 GO:0003824 ... P51541 27594681
    392 5jwg:A (2.2) BS01 ARG 3.4.14.- GO:0004177 ... F8WQK8 28588213
    393 5jwg:B (2.2) BS01 ARG 3.4.14.- GO:0004177 ... F8WQK8 28588213
    394 5jwi:A (2.1) BS01 ARG 3.4.14.- GO:0004177 ... F8WQK8 28588213
    395 5jwi:B (2.1) BS01 ARG 3.4.14.- GO:0004177 ... F8WQK8 28588213
    396 5jxf:A (2.1) BS01 ARG 3.4.14.- GO:0004177 ... A6GWM2 28588213
    397 5jxf:B (2.1) BS01 ARG 3.4.14.- GO:0004177 ... A6GWM2 28588213
    398 5lt9:A (3.0) BS01 ARG ? N/A Q9HW91 N/A PDBbind: -logKd/Ki=4.19, Kd=64uM
    399 5lt9:B (3.0) BS01 ARG ? N/A Q9HW91 N/A
    400 5lun:A (1.08) BS02 ARG 1.13.12.19
    1.14.20.7
    GO:0009693 ... P32021 28420789

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218