Home Research COVID-19 Services Publications People Teaching Job Opening News Forum --> -->
Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
Download all results in tab-seperated text for 17 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

    • Sort results by
    << < 1 > >>
    Go to page

    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1av5:B (2.0) BS01 AP2 3.4.22.-
    3.9.1.-    		 GO:0000118 ... P49773 9323207
    2 1dku:A (2.2) BS01 AP2 2.7.6.1 GO:0000287 ... P14193 10742175
    3 1dku:A (2.2) BS03 AP2 2.7.6.1 GO:0000287 ... P14193 10742175
    4 1dku:B (2.2) BS01 AP2 2.7.6.1 GO:0000287 ... P14193 10742175
    5 1dku:B (2.2) BS02 AP2 2.7.6.1 GO:0000287 ... P14193 10742175
    6 2vqd:A (2.41) BS01 AP2 6.3.4.14 GO:0003824 ... P37798 18725455
    7 3fd5:A (1.9) BS01 AP2 2.7.9.3 GO:0004756 ... P49903 19477186
    8 3fd5:A (1.9) BS06 AP2 2.7.9.3 GO:0004756 ... P49903 19477186
    9 3fd5:B (1.9) BS01 AP2 2.7.9.3 GO:0004756 ... P49903 19477186
    10 3fd5:B (1.9) BS02 AP2 2.7.9.3 GO:0004756 ... P49903 19477186
    11 3vth:A (2.0) BS04 AP2 3.6.1.7
    6.2.-.-    		 GO:0003725 ... Q8RDB0 22740694
    12 3vth:B (2.0) BS04 AP2 3.6.1.7
    6.2.-.-    		 GO:0003725 ... Q8RDB0 22740694
    13 5fc6:A (1.658) BS03 AP2 3.1.4.-
    3.6.1.15    		 GO:0004767 ... P70158 26792860
    14 5fit:A (2.3) BS01 AP2 2.7.7.51
    3.6.1.29
    3.6.2.1
    3.9.1.-    		 GO:0000166 ... P49789 9323207
    15 6tvg:A (1.48) BS03 AP2 3.1.3.35
    3.1.3.5
    3.1.3.89
    3.1.3.91
    3.1.3.99    		 GO:0000166 ... P21589 32045236 MOAD: Ki=88.4nM
    16 8a8m:A (4.0) BS01 AP2 2.7.11.24 GO:0000077 ... Q16539 37708276
    17 8a8m:B (4.0) BS01 AP2 2.7.12.2 GO:0000165 ... P52564 37708276
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

    • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218