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BioLiP
Download all results in tab-seperated text for 31 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1cea:A (2.06) BS01 ACA 3.4.21.7 N/A P00747 8611560 MOAD: Kd~11uM
    PDBbind: -logKd/Ki=4.96, Kd=11uM
    BindingDB: Ki=53000000nM, Kd=9000nM, IC50=105000nM
    2 1cea:B (2.06) BS01 ACA 3.4.21.7 N/A P00747 8611560 MOAD: Kd~11uM
    PDBbind: -logKd/Ki=4.96, Kd=11uM
    BindingDB: Ki=53000000nM, Kd=9000nM, IC50=105000nM
    3 1hpk:A (-1.00) BS01 ACA 3.4.21.7 N/A P00747 8181476 BindingDB: Ki=53000000nM, Kd=9000nM, IC50=105000nM
    4 1pk2:A (-1.00) BS01 ACA 3.4.21.68 N/A P00750 1762144
    5 2dcf:A (1.4) BS01 ACA 3.5.1.46 GO:0016787 ... P07062 17512009
    6 2dcf:A (1.4) BS02 ACA 3.5.1.46 GO:0016787 ... P07062 17512009
    7 2pk4:A (2.25) BS01 ACA 3.4.21.7 N/A P00747 1657149 BindingDB: Ki=53000000nM, Kd=9000nM, IC50=105000nM
    8 2zm7:A (1.6) BS01 ACA 3.5.1.46 N/A P07061
    P07062    		 19476493
    9 2zm7:A (1.6) BS02 ACA 3.5.1.46 N/A P07061
    P07062    		 19476493
    10 2zm8:A (1.55) BS01 ACA 3.5.1.46 N/A P07061
    P07062    		 19521995
    11 2zm8:A (1.55) BS02 ACA 3.5.1.46 N/A P07061
    P07062    		 19521995
    12 2zm9:A (1.5) BS01 ACA 3.5.1.46 N/A P07061
    P07062    		 19521995
    13 2zm9:A (1.5) BS02 ACA 3.5.1.46 N/A P07061
    P07062    		 19521995
    14 2zma:A (1.51) BS01 ACA 3.5.1.46 N/A P07061
    P07062    		 19476493
    15 2zma:A (1.51) BS02 ACA 3.5.1.46 N/A P07061
    P07062    		 19476493
    16 3a2q:A (1.8) BS01 ACA 3.5.2.12 GO:0003824 ... P13398 19889645
    17 3a2q:A (1.8) BS02 ACA 3.5.2.12 GO:0003824 ... P13398 19889645
    18 3a65:A (1.7) BS01 ACA 3.5.1.46 N/A P07061
    P07062    		 N/A
    19 3a66:A (1.6) BS01 ACA 3.5.1.46 N/A P07061
    P07062    		 N/A
    20 3kiv:A (1.8) BS01 ACA 3.4.21.- N/A P08519 10026282 MOAD: Kd=20uM
    PDBbind: -logKd/Ki=4.70, Kd=20uM
    21 3vwp:A (1.55) BS01 ACA 3.5.1.46 N/A P07061
    P07062    		 N/A
    22 3vwq:A (1.7) BS01 ACA 3.5.1.46 N/A P07061
    P07062    		 N/A
    23 3vwr:A (1.65) BS01 ACA 3.5.1.46 N/A P07061
    P07062    		 N/A
    24 4dxu:A (1.46) BS04 ACA 3.4.21.- GO:0005576 ... P24627 N/A
    25 4g24:A (1.95) BS03 ACA 3.1.26.5 N/A Q66GI4 22991464
    26 4hxy:B (1.68) BS02 ACA ? N/A Q6V1M8 23790488
    27 4laj:A (2.14) BS02 ACA ? GO:0019031 ... P35961 23843638
    28 4laj:B (2.14) BS02 ACA ? GO:0019031 ... P35961 23843638
    29 6dcm:A (1.031) BS01 ACA N/A N/A N/A N/A
    30 6g4e:A (2.45) BS02 ACA N/A GO:0008483 ... N/A 31162815
    31 6nk0:A (1.53) BS02 ACA 2.7.10.1 N/A P29317 31015204
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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