Home Research COVID-19 Services Publications People Teaching Job Opening News Forum --> -->
Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
Download all results in tab-seperated text for 28 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

    • Sort results by
    << < 1 > >>
    Go to page

    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1mui:A (2.8) BS01 AB1 3.4.23.16 GO:0004190 ... Q903J0 12057670 PDBbind: -logKd/Ki=11.89, Ki=1.3pM
    2 1mui:B (2.8) BS01 AB1 3.4.23.16 GO:0004190 ... Q903J0 12057670 PDBbind: -logKd/Ki=11.89, Ki=1.3pM
    3 1rv7:A (2.7) BS01 AB1 3.4.23.16 GO:0004190 ... Q9QM22 14990731
    4 1rv7:B (2.7) BS01 AB1 3.4.23.16 GO:0004190 ... Q9QM22 14990731
    5 2o4s:A (1.54) BS01 AB1 ? GO:0004190 ... Q5RZ08 17360759 MOAD: Kd=31pM
    PDBbind: -logKd/Ki=10.51, Kd=31pM
    6 2o4s:B (1.54) BS01 AB1 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P03367 17360759 PDBbind: -logKd/Ki=10.51, Kd=31pM
    7 2q5k:A (1.95) BS01 AB1 ? GO:0004190 ... O38710 17696512 MOAD: Ki=0.005nM
    PDBbind: -logKd/Ki=11.30, Ki=5pM
    8 2q5k:B (1.95) BS01 AB1 ? GO:0004190 ... O38710 17696512 PDBbind: -logKd/Ki=11.30, Ki=5pM
    9 2qhc:A (2.802) BS01 AB1 3.4.23.16 GO:0004190 ... Q9J2P7 18560011 PDBbind: -logKd/Ki=8.96, Ki=1.1nM
    10 2qhc:B (2.802) BS01 AB1 3.4.23.16 GO:0004190 ... Q9J2P7 18560011 PDBbind: -logKd/Ki=8.96, Ki=1.1nM
    11 2rkf:A (1.8) BS01 AB1 3.1.26.13 GO:0004190 ... Q90JJ9 18400858 MOAD: Ki=0.83nM
    PDBbind: -logKd/Ki=9.08, Ki=0.83nM
    12 2rkf:B (1.8) BS01 AB1 3.1.26.13 GO:0004190 ... Q90JJ9 18400858 PDBbind: -logKd/Ki=9.08, Ki=0.83nM
    13 2rkg:A (1.8) BS01 AB1 3.1.26.13 GO:0004190 ... A0F6C5 18400858 PDBbind: -logKd/Ki=8.09, Ki=8.2nM
    14 2rkg:B (1.8) BS01 AB1 3.1.26.13 GO:0004190 ... A0F6C5 18400858 MOAD: Ki=8.2nM
    PDBbind: -logKd/Ki=8.09, Ki=8.2nM
    15 2z54:A (2.31) BS01 AB1 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P04587 18560011
    16 2z54:B (2.31) BS01 AB1 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P04587 18560011
    17 3ogq:A (1.8) BS01 AB1 2.7.7.-
    2.7.7.49
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.-
    3.6.1.23    		 GO:0004190 ... P16088 21636894 MOAD: ic50=30nM
    PDBbind: -logKd/Ki=7.52, IC50=30nM
    18 3ogq:B (1.8) BS01 AB1 2.7.7.-
    2.7.7.49
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.-
    3.6.1.23    		 GO:0004190 ... P16088 21636894 PDBbind: -logKd/Ki=7.52, IC50=30nM
    19 4l1a:A (1.9) BS01 AB1 3.1.26.13 GO:0004190 ... Q000H7 23792096 MOAD: ic50=5.39nM
    PDBbind: -logKd/Ki=8.27, IC50=5.39nM
    20 4l1a:B (1.9) BS01 AB1 3.1.26.13 GO:0004190 ... Q000H7 23792096 PDBbind: -logKd/Ki=8.27, IC50=5.39nM
    21 6dj1:A (1.26) BS01 AB1 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P04585 30288468 PDBbind: -logKd/Ki=10.51, Ki=0.031nM
    22 6dj1:B (1.26) BS01 AB1 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P04585 30288468 MOAD: Ki=0.031nM
    PDBbind: -logKd/Ki=10.51, Ki=0.031nM
    23 6dj2:A (1.36) BS01 AB1 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P04585 30288468 PDBbind: -logKd/Ki=8.12, Ki=7.6nM
    24 6dj2:B (1.36) BS01 AB1 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P04585 30288468 MOAD: Ki=4.5nM
    PDBbind: -logKd/Ki=8.12, Ki=7.6nM
    25 6pjb:A (1.984) BS01 AB1 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P12497 32672965
    26 6pjb:B (1.984) BS01 AB1 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P12497 32672965
    27 7ve2:A (3.2) BS01 AB1 3.4.23.39 GO:0004190 ... Q8I6V3 38304146
    28 9g35:A (1.5) BS01 AB1 N/A N/A P11838 N/A
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

    • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218