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BioLiP
Download all results in tab-seperated text for 14 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 2y03:A (2.85) BS04 5FW ? GO:0004930 ... P07700 21228877
    2 2y03:B (2.85) BS05 5FW ? GO:0004930 ... P07700 21228877
    3 4a7t:A (1.45) BS01 5FW 1.15.1.1 GO:0000302 ... P00441 23612299
    4 4a7t:A (1.45) BS02 5FW 1.15.1.1 GO:0000302 ... P00441 23612299
    5 4a7t:F (1.45) BS01 5FW 1.15.1.1 GO:0000302 ... P00441 23612299
    6 4a7t:F (1.45) BS02 5FW 1.15.1.1 GO:0000302 ... P00441 23612299
    7 5ytu:A (1.9) BS01 5FW 1.15.1.1 GO:0000302 ... P00441 29679384 MOAD: Kd=12uM
    PDBbind: -logKd/Ki=4.92, Kd=12uM
    8 6h7j:A (2.8) BS01 5FW ? GO:0004930 ... P07700 31072904 PDBbind: -logKd/Ki=8.62, Ki=2.4nM
    9 6h7j:B (2.8) BS02 5FW ? GO:0004930 ... P07700 31072904
    10 7dhr:R (3.8) BS01 5FW ? GO:0004930 ... P07550 N/A BindingDB: Ki=46nM, EC50=1.2nM, Kd=130nM, IC50=0.05nM
    11 7jjo:R (2.6) BS01 5FW ? GO:0003796 ... P07700 32818430
    12 7s0f:R (2.96) BS01 5FW ? GO:0003796 ... P07700 34759376
    13 7s0g:R (3.86) BS01 5FW ? GO:0003796 ... P07700 34759376
    14 7xjh:R (3.3) BS01 5FW ? GO:0004930 ... O02662 34314699
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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