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BioLiP
Download all results in tab-seperated text for 24 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 2qcf:A (1.22) BS01 5FU 2.4.2.10
    4.1.1.23    		 GO:0004590 ... P11172 18184586 PDBbind: -logKd/Ki=3.49, IC50=320uM
    BindingDB: Ki=98000nM
    2 2vp6:A (3.0) BS01 5FU 2.7.1.145 GO:0004136 ... Q9XZT6 18384378
    3 2vp6:B (3.0) BS01 5FU 2.7.1.145 GO:0004136 ... Q9XZT6 18384378
    4 2vp6:C (3.0) BS01 5FU 2.7.1.145 GO:0004136 ... Q9XZT6 18384378
    5 2vp6:D (3.0) BS01 5FU 2.7.1.145 GO:0004136 ... Q9XZT6 18384378
    6 2vp6:E (3.0) BS01 5FU 2.7.1.145 GO:0004136 ... Q9XZT6 18384378
    7 2vp6:F (3.0) BS01 5FU 2.7.1.145 GO:0004136 ... Q9XZT6 18384378
    8 2vp6:G (3.0) BS01 5FU 2.7.1.145 GO:0004136 ... Q9XZT6 18384378
    9 2vp6:H (3.0) BS01 5FU 2.7.1.145 GO:0004136 ... Q9XZT6 18384378
    10 3g1v:A (1.3) BS01 5FU 4.1.1.23 GO:0004590 ... O26232 19435314 PDBbind: -logKd/Ki=3.19, Ki=645uM
    BindingDB: Ki=645000nM
    11 3g1v:A (1.3) BS02 5FU 4.1.1.23 GO:0004590 ... O26232 19435314 PDBbind: -logKd/Ki=3.19, Ki=645uM
    BindingDB: Ki=645000nM
    12 3g1v:B (1.3) BS01 5FU 4.1.1.23 GO:0004590 ... O26232 19435314 PDBbind: -logKd/Ki=3.19, Ki=645uM
    BindingDB: Ki=645000nM
    13 3g1v:B (1.3) BS02 5FU 4.1.1.23 GO:0004590 ... O26232 19435314 PDBbind: -logKd/Ki=3.19, Ki=645uM
    BindingDB: Ki=645000nM
    14 3g3d:A (1.7) BS01 5FU 2.4.2.10
    4.1.1.23    		 GO:0004590 ... P11172 19260677 PDBbind: -logKd/Ki=4.74, Ki=18.2uM
    BindingDB: Ki=98000nM
    15 3g3d:A (1.7) BS02 5FU 2.4.2.10
    4.1.1.23    		 GO:0004590 ... P11172 19260677 PDBbind: -logKd/Ki=4.74, Ki=18.2uM
    BindingDB: Ki=98000nM
    16 3g3d:B (1.7) BS01 5FU 2.4.2.10
    4.1.1.23    		 GO:0004590 ... P11172 19260677 PDBbind: -logKd/Ki=4.74, Ki=18.2uM
    BindingDB: Ki=98000nM
    17 3g3d:B (1.7) BS02 5FU 2.4.2.10
    4.1.1.23    		 GO:0004590 ... P11172 19260677 PDBbind: -logKd/Ki=4.74, Ki=18.2uM
    BindingDB: Ki=98000nM
    18 3g3m:A (1.4) BS01 5FU 2.4.2.10
    4.1.1.23    		 GO:0004590 ... P11172 19260677 PDBbind: -logKd/Ki=5.96, Ki=1.1uM
    BindingDB: Ki=98000nM
    19 3mw7:A (2.32) BS01 5FU 2.4.2.10
    4.1.1.23    		 GO:0004590 ... P11172 N/A BindingDB: Ki=98000nM
    20 3mw7:A (2.32) BS02 5FU 2.4.2.10
    4.1.1.23    		 GO:0004590 ... P11172 N/A BindingDB: Ki=98000nM
    21 3mw7:B (2.32) BS01 5FU 2.4.2.10
    4.1.1.23    		 GO:0004590 ... P11172 N/A BindingDB: Ki=98000nM
    22 3mw7:B (2.32) BS02 5FU 2.4.2.10
    4.1.1.23    		 GO:0004590 ... P11172 N/A BindingDB: Ki=98000nM
    23 3sgu:A (1.7) BS01 5FU 4.1.1.23 GO:0004590 ... O26232 N/A BindingDB: Ki=645000nM
    24 3sw6:A (1.5) BS01 5FU 4.1.1.23 GO:0004590 ... O26232 N/A BindingDB: Ki=645000nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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