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BioLiP
Download all results in tab-seperated text for 50 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1b55:A (2.4) BS02 4IP 2.7.10.2 GO:0035556 ... Q06187 10196129 MOAD: Kd=40nM
    PDBbind: -logKd/Ki=7.40, Kd=40nM
    2 1b55:B (2.4) BS02 4IP 2.7.10.2 GO:0035556 ... Q06187 10196129 MOAD: Kd=40nM
    PDBbind: -logKd/Ki=7.40, Kd=40nM
    3 1bwn:A (2.1) BS02 4IP 2.7.10.2 GO:0035556 ... Q06187 10196129 MOAD: Kd=87nM
    PDBbind: -logKd/Ki=7.06, Kd=87nM
    4 1bwn:A (2.1) BS03 4IP 2.7.10.2 GO:0035556 ... Q06187 10196129 MOAD: Kd=87nM
    PDBbind: -logKd/Ki=7.06, Kd=87nM
    5 1bwn:B (2.1) BS02 4IP 2.7.10.2 GO:0035556 ... Q06187 10196129 MOAD: Kd=87nM
    PDBbind: -logKd/Ki=7.06, Kd=87nM
    6 1bwn:B (2.1) BS03 4IP 2.7.10.2 GO:0035556 ... Q06187 10196129 MOAD: Kd=87nM
    PDBbind: -logKd/Ki=7.06, Kd=87nM
    7 1fao:A (1.8) BS01 4IP ? N/A Q9UN19 10983984 MOAD: Kd=0.043uM
    PDBbind: -logKd/Ki=7.37, Kd=0.043uM
    8 1fgy:A (1.5) BS01 4IP ? N/A O08967 10983985
    9 1fhx:A (2.5) BS01 4IP ? N/A O08967 10983984 MOAD: Kd=0.027uM
    10 1fhx:B (2.5) BS01 4IP ? N/A O08967 10983984 MOAD: Kd=0.027uM
    11 1h10:A (1.4) BS01 4IP 2.7.11.1 N/A P31749 12176338
    12 1u27:A (2.3) BS01 4IP ? N/A P63034 15359279
    13 1unq:A (0.98) BS01 4IP 2.7.11.1 N/A P31749 12964941
    14 1upr:A (2.27) BS01 4IP ? N/A Q9H4M7 N/A
    15 1w1d:A (1.5) BS01 4IP 2.7.11.1 N/A O15530 15457207 MOAD: Ki=0.3uM
    PDBbind: -logKd/Ki=6.52, Ki=0.30uM
    16 1w2d:A (1.94) BS02 4IP 2.7.1.127 GO:0016301 ... P23677 15350214
    17 1w2d:B (1.94) BS02 4IP 2.7.1.127 GO:0016301 ... P23677 15350214
    18 2lko:A (-1.00) BS01 4IP ? GO:0007229 ... Q96AC1 22030399 PDBbind: -logKd/Ki=5.67, Kd=2.12uM
    19 2r09:A (1.9) BS01 4IP ? GO:0005085 ... O08967 18042453
    20 2r09:B (1.9) BS01 4IP ? GO:0005085 ... O08967 18042453
    21 2r0d:A (2.04) BS01 4IP ? GO:0005085 ... O08967 18042453
    22 2r0d:B (2.04) BS01 4IP ? GO:0005085 ... O08967 18042453
    23 2uzs:A (2.46) BS01 4IP 2.7.11.1 N/A P31749 17611497
    24 3ajm:B (2.3) BS01 4IP ? GO:0000139 ... Q9BUL8 20682288
    25 3o3l:A (1.85) BS01 4IP ? GO:0016787 ... Q7WUJ1 N/A
    26 3o3l:B (1.85) BS01 4IP ? GO:0016787 ... Q7WUJ1 N/A
    27 4kax:B (1.85) BS01 4IP ? N/A O43739 23940353
    28 4wty:A (2.1) BS01 4IP ? GO:0016787 ... Q7WUJ1 N/A
    29 4wty:B (2.1) BS01 4IP ? GO:0016787 ... Q7WUJ1 N/A
    30 4wu3:A (2.2) BS01 4IP 3.1.3.8 GO:0004725 ... A3QMF6 N/A
    31 4wu3:A (2.2) BS02 4IP 3.1.3.8 GO:0004725 ... A3QMF6 N/A
    32 4wu3:B (2.2) BS01 4IP 3.1.3.8 GO:0004725 ... A3QMF6 N/A
    33 4wu3:C (2.2) BS01 4IP 3.1.3.8 GO:0004725 ... A3QMF6 N/A
    34 4wu3:C (2.2) BS02 4IP 3.1.3.8 GO:0004725 ... A3QMF6 N/A
    35 4wu3:D (2.2) BS01 4IP 3.1.3.8 GO:0004725 ... A3QMF6 N/A
    36 5d3x:A (1.69) BS01 4IP ? N/A Q8TCU6 27150042 MOAD: Kd=440nM
    PDBbind: -logKd/Ki=6.36, Kd=440nM
    37 5d3x:B (1.69) BS01 4IP ? N/A Q8TCU6 27150042 MOAD: Kd=440nM
    38 5d3y:A (1.95) BS01 4IP ? N/A Q8TCU6 27150042 MOAD: Kd=440nM
    39 5d3y:B (1.95) BS01 4IP ? N/A Q8TCU6 27150042 MOAD: Kd=440nM
    40 6bbp:A (35.0) BS03 4IP ?
    3.6.5.2    		 GO:0001726 ... O08967
    P62330    		 29276036
    41 6bbq:A (35.0) BS03 4IP ?
    3.6.5.2    		 GO:0001726 ... O08967
    P62330    		 29276036
    42 6u3e:A (53.0) BS01 4IP ? GO:0000139 ... O43739 31601460
    43 6u3e:B (53.0) BS01 4IP ? GO:0000139 ... O43739 31601460
    44 6u3g:A (53.0) BS01 4IP ? GO:0000139 ... O43739 31601460
    45 6u3g:B (53.0) BS01 4IP ? GO:0000139 ... O43739 31601460
    46 7kjz:A (2.43) BS01 4IP ? N/A Q6IQ23 33878292
    47 7kjz:B (2.43) BS01 4IP ? N/A Q6IQ23 33878292
    48 7kjz:B (2.43) BS02 4IP ? N/A Q6IQ23 33878292
    49 7sdd:A (1.85) BS01 4IP 3.1.3.48 GO:0004725 ... Q5ZRR1 N/A
    50 8tua:A (4.1) BS01 4IP ? GO:0005085 ... Q8TCU6 N/A
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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