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BioLiP
Download all results in tab-seperated text for 26 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 2n27:A (-1.00) BS04 4DY ? GO:0000086 ... P0DP23 27339229 PDBbind: -logKd/Ki=6.55, Kd=280nM
    2 7lpa:A (3.37) BS03 4DY ? GO:0000122 ... O35433 34239123 BindingDB: EC50=300nM, Ki=2000nM, IC50=19nM
    3 7lpa:B (3.37) BS04 4DY ? GO:0000122 ... O35433 34239123 BindingDB: EC50=300nM, Ki=2000nM, IC50=19nM
    4 7lpa:C (3.37) BS04 4DY ? GO:0000122 ... O35433 34239123 BindingDB: EC50=300nM, Ki=2000nM, IC50=19nM
    5 7lpa:D (3.37) BS04 4DY ? GO:0000122 ... O35433 34239123 BindingDB: EC50=300nM, Ki=2000nM, IC50=19nM
    6 7lpb:A (3.54) BS03 4DY ? GO:0000122 ... O35433 34239123 BindingDB: EC50=300nM, Ki=2000nM, IC50=19nM
    7 7lpb:B (3.54) BS05 4DY ? GO:0000122 ... O35433 34239123 BindingDB: EC50=300nM, Ki=2000nM, IC50=19nM
    8 7lpb:C (3.54) BS05 4DY ? GO:0000122 ... O35433 34239123 BindingDB: EC50=300nM, Ki=2000nM, IC50=19nM
    9 7lpb:D (3.54) BS05 4DY ? GO:0000122 ... O35433 34239123 BindingDB: EC50=300nM, Ki=2000nM, IC50=19nM
    10 7lpd:A (3.55) BS02 4DY ? GO:0000122 ... O35433 34239123 BindingDB: EC50=300nM, Ki=2000nM, IC50=19nM
    11 7lpd:B (3.55) BS02 4DY ? GO:0000122 ... O35433 34239123 BindingDB: EC50=300nM, Ki=2000nM, IC50=19nM
    12 7lpd:C (3.55) BS02 4DY ? GO:0000122 ... O35433 34239123 BindingDB: EC50=300nM, Ki=2000nM, IC50=19nM
    13 7lpd:D (3.55) BS02 4DY ? GO:0000122 ... O35433 34239123 BindingDB: EC50=300nM, Ki=2000nM, IC50=19nM
    14 7lpe:A (3.72) BS03 4DY ? GO:0000122 ... O35433 34239123 BindingDB: EC50=300nM, Ki=2000nM, IC50=19nM
    15 7lpe:B (3.72) BS03 4DY ? GO:0000122 ... O35433 34239123 BindingDB: EC50=300nM, Ki=2000nM, IC50=19nM
    16 7lpe:C (3.72) BS03 4DY ? GO:0000122 ... O35433 34239123 BindingDB: EC50=300nM, Ki=2000nM, IC50=19nM
    17 7lpe:D (3.72) BS03 4DY ? GO:0000122 ... O35433 34239123 BindingDB: EC50=300nM, Ki=2000nM, IC50=19nM
    18 7lr0:A (3.81) BS01 4DY ? GO:0000122 ... I3LZN5 33846324
    19 7lr0:A (3.81) BS02 4DY ? GO:0000122 ... I3LZN5 33846324
    20 7lr0:B (3.81) BS01 4DY ? GO:0000122 ... I3LZN5 33846324
    21 7lr0:B (3.81) BS02 4DY ? GO:0000122 ... I3LZN5 33846324
    22 7lr0:C (3.81) BS01 4DY ? GO:0000122 ... I3LZN5 33846324
    23 7lr0:C (3.81) BS02 4DY ? GO:0000122 ... I3LZN5 33846324
    24 7lr0:D (3.81) BS01 4DY ? GO:0000122 ... I3LZN5 33846324
    25 7lr0:D (3.81) BS02 4DY ? GO:0000122 ... I3LZN5 33846324
    26 7vek:B (2.6) BS02 4DY 2.4.1.- GO:0008194 ... B5MGN9 35234151
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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