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BioLiP
Download all results in tab-seperated text for 14 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 4nr7:A (1.2) BS01 2LO 2.3.1.-
    2.3.1.48    		 GO:0004402 ... Q92793 N/A BindingDB: Kd=21nM, IC50=2800nM, EC50=6900nM
    2 5bt3:A (1.05) BS01 2LO 2.3.1.-
    2.3.1.48    		 GO:0004402 ... Q09472 N/A BindingDB: Kd=31847134nM, IC50=230nM
    3 5bt4:A (1.5) BS01 2LO ? N/A O60885 N/A BindingDB: Kd=8.5e+2nM, IC50=7121nM
    4 5bt4:B (1.5) BS01 2LO ? N/A O60885 N/A BindingDB: Kd=8.5e+2nM, IC50=7121nM
    5 5bt4:B (1.5) BS02 2LO ? N/A O60885 N/A BindingDB: Kd=8.5e+2nM, IC50=7121nM
    6 5bt4:C (1.5) BS01 2LO ? N/A O60885 N/A BindingDB: Kd=8.5e+2nM, IC50=7121nM
    7 5bt4:C (1.5) BS02 2LO ? N/A O60885 N/A BindingDB: Kd=8.5e+2nM, IC50=7121nM
    8 5bt5:A (1.4) BS01 2LO ? N/A P25440 N/A
    9 6bya:A (2.26) BS01 2LO ? N/A A0A3Q8I8I6 N/A
    10 6bya:B (2.26) BS01 2LO ? N/A A0A3Q8I8I6 N/A
    11 6bya:C (2.26) BS01 2LO ? N/A A0A3Q8I8I6 N/A
    12 6bya:D (2.26) BS01 2LO ? N/A A0A3Q8I8I6 N/A
    13 7ugl:A (1.5) BS02 2LO 2.3.1.-
    2.3.1.48    		 GO:0004402 ... Q92793 N/A
    14 7ugl:B (1.5) BS03 2LO 2.3.1.-
    2.3.1.48    		 GO:0004402 ... Q92793 N/A
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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