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BioLiP
Download all results in tab-seperated text for 126 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 3c1y:A (2.1) BS01 2BA 2.7.7.85 GO:0003677 ... Q9WY43 18439896
    2 3c1y:B (2.1) BS01 2BA 2.7.7.85 GO:0003677 ... Q9WY43 18439896
    3 3c21:A (2.7) BS01 2BA 2.7.7.85 GO:0003677 ... Q9WY43 18439896
    4 3c21:B (2.7) BS01 2BA 2.7.7.85 GO:0003677 ... Q9WY43 18439896
    5 4d3h:A (2.0) BS01 2BA ? N/A Q2G229 25505271 MOAD: Kd=0.37uM
    PDBbind: -logKd/Ki=6.43, Kd=0.37uM
    6 4d3h:A (2.0) BS02 2BA ? N/A Q2G229 25505271 MOAD: Kd=0.37uM
    PDBbind: -logKd/Ki=6.43, Kd=0.37uM
    7 4d3h:B (2.0) BS01 2BA ? N/A Q2G229 25505271 MOAD: Kd=0.37uM
    PDBbind: -logKd/Ki=6.43, Kd=0.37uM
    8 4d3h:B (2.0) BS02 2BA ? N/A Q2G229 25505271 MOAD: Kd=0.37uM
    PDBbind: -logKd/Ki=6.43, Kd=0.37uM
    9 4d3h:C (2.0) BS01 2BA ? N/A Q2G229 25505271 MOAD: Kd=0.37uM
    10 4d3h:C (2.0) BS02 2BA ? N/A Q2G229 25505271 MOAD: Kd=0.37uM
    11 4qsh:A (2.51) BS02 2BA N/A GO:0003824 ... N/A 25215494 PDBbind: -logKd/Ki=5.10, Kd=8uM
    12 4qsh:B (2.51) BS02 2BA N/A GO:0003824 ... N/A 25215494
    13 4qsh:C (2.51) BS01 2BA N/A GO:0003824 ... N/A 25215494
    14 4qsh:D (2.51) BS01 2BA N/A GO:0003824 ... N/A 25215494 PDBbind: -logKd/Ki=5.10, Kd=8uM
    15 4qsk:A (2.7) BS01 2BA N/A GO:0003824 ... N/A 25215494 PDBbind: -logKd/Ki=5.10, Kd=8uM
    16 4qsk:B (2.7) BS02 2BA N/A GO:0003824 ... N/A 25215494
    17 4rle:A (1.3) BS01 2BA ? GO:0005737 ... P37538 25433025
    18 4rww:A (1.6) BS01 2BA ? N/A Q8Y3Y7 25693966 PDBbind: -logKd/Ki=5.85, Kd=1.4uM
    19 4rww:A (1.6) BS02 2BA ? N/A Q8Y3Y7 25693966 PDBbind: -logKd/Ki=5.85, Kd=1.4uM
    20 4rww:A (1.6) BS03 2BA ? N/A Q8Y3Y7 25693966 PDBbind: -logKd/Ki=5.85, Kd=1.4uM
    21 4rww:B (1.6) BS01 2BA ? N/A Q8Y3Y7 25693966 PDBbind: -logKd/Ki=5.85, Kd=1.4uM
    22 4rww:B (1.6) BS02 2BA ? N/A Q8Y3Y7 25693966 PDBbind: -logKd/Ki=5.85, Kd=1.4uM
    23 4rww:C (1.6) BS01 2BA ? N/A Q8Y3Y7 25693966
    24 4rww:C (1.6) BS02 2BA ? N/A Q8Y3Y7 25693966
    25 4s1b:A (2.099) BS03 2BA ? N/A Q8Y746 25583510 MOAD: Kd=0.3uM
    26 4s1b:A (2.099) BS04 2BA ? N/A Q8Y746 25583510 MOAD: Kd=0.3uM
    27 4s1b:D (2.099) BS03 2BA ? N/A Q8Y746 25583510 MOAD: Kd=0.3uM
    28 4wk1:A (1.98) BS01 2BA ? GO:0046872 ... A0A0H2WXZ7 25435171 MOAD: Kd=109nM
    PDBbind: -logKd/Ki=5.89, Kd=1.3uM
    29 4xtt:A (2.708) BS01 2BA ? GO:0006813 ... A0A0M3KL06 25957408 PDBbind: -logKd/Ki=7.37, Kd=43.1nM
    30 4xtt:B (2.708) BS01 2BA ? GO:0006813 ... A0A0M3KL06 25957408 PDBbind: -logKd/Ki=7.37, Kd=43.1nM
    31 4yp1:A (2.65) BS01 2BA ? GO:0002218 ... Q3TBT3 26171638 PDBbind: -logKd/Ki=5.04, Kd=9.1uM
    32 4yp1:B (2.65) BS01 2BA ? GO:0002218 ... Q3TBT3 26171638 PDBbind: -logKd/Ki=5.04, Kd=9.1uM
    33 4ys2:A (1.968) BS01 2BA ? GO:0006813 ... Q2FZQ4 N/A
    34 4ys2:B (1.968) BS01 2BA ? GO:0006813 ... Q2FZQ4 N/A
    35 4yxm:A (2.25) BS01 2BA 2.7.7.85 GO:0003677 ... Q9WY43 26014055
    36 4yxm:B (2.25) BS01 2BA 2.7.7.85 GO:0003677 ... Q9WY43 26014055
    37 5cfn:A (2.95) BS01 2BA ? GO:0002218 ... A7SLZ2 26300263
    38 5cfn:A (2.95) BS02 2BA ? GO:0002218 ... A7SLZ2 26300263
    39 5cfn:B (2.95) BS01 2BA ? GO:0002218 ... A7SLZ2 26300263
    40 5cfn:B (2.95) BS02 2BA ? GO:0002218 ... A7SLZ2 26300263
    41 5f29:A (1.821) BS01 2BA ? GO:0006813 ... Q2FZQ4 26171638 PDBbind: -logKd/Ki=5.05, Kd~9uM
    42 5f29:B (1.821) BS01 2BA ? GO:0006813 ... Q2FZQ4 26171638 PDBbind: -logKd/Ki=5.05, Kd~9uM
    43 5ks7:A (2.9) BS01 2BA 7.6.2.9 N/A Q9KHT9 27378384 PDBbind: -logKd/Ki=5.32, Kd=4.8uM
    44 5ks7:B (2.9) BS01 2BA 7.6.2.9 N/A Q9KHT9 27378384 PDBbind: -logKd/Ki=5.32, Kd=4.8uM
    45 5uxf:A (1.501) BS01 2BA 1.1.1.- GO:0004033 ... Q8VC28 28329705 MOAD: Kd=87nM
    PDBbind: -logKd/Ki=7.06, Kd=87nM
    46 5vyz:A (2.3) BS04 2BA N/A GO:0003824 ... N/A 28808024
    47 5vyz:B (2.3) BS01 2BA N/A GO:0003824 ... N/A 28808024
    48 5vyz:C (2.3) BS04 2BA N/A GO:0003824 ... N/A 28808024
    49 5vyz:D (2.3) BS01 2BA N/A GO:0003824 ... N/A 28808024
    50 5vz0:A (2.0) BS04 2BA N/A GO:0003824 ... N/A 28808024
    51 5vz0:B (2.0) BS01 2BA N/A GO:0003824 ... N/A 28808024
    52 5vz0:C (2.0) BS02 2BA N/A GO:0003824 ... N/A 28808024
    53 5vz0:D (2.0) BS01 2BA N/A GO:0003824 ... N/A 28808024
    54 5xsn:A (2.501) BS03 2BA 3.1.4.- GO:0003676 ... A0A0U1MUE2 29203646
    55 5xsn:B (2.501) BS03 2BA 3.1.4.- GO:0003676 ... A0A0U1MUE2 29203646
    56 6a03:A (2.597) BS01 2BA ? GO:0002218 ... B8XX90 31167783
    57 6a03:B (2.597) BS01 2BA ? GO:0002218 ... B8XX90 31167783
    58 6cff:A (2.396) BS01 2BA ? GO:0002218 ... Q86WV6 31230712 BindingDB: EC50=200nM
    59 6cy7:A (2.2) BS01 2BA ? GO:0002218 ... Q86WV6 31230712 BindingDB: EC50=200nM
    60 6hvl:A (2.8) BS01 2BA 2.7.7.85 GO:0004016 ... Q8Y5E4 31118276
    61 6iyf:A (1.764) BS01 2BA ? GO:0002218 ... B8XX90 31167783
    62 6iyf:B (1.764) BS01 2BA ? GO:0002218 ... B8XX90 31167783 MOAD: Kd~6uM
    63 6xnv:A (2.4) BS01 2BA ? N/A Q8Y8A3 32843560
    64 6xnv:A (2.4) BS02 2BA ? N/A Q8Y8A3 32843560
    65 6xnv:B (2.4) BS01 2BA ? N/A Q8Y8A3 32843560
    66 6xnv:B (2.4) BS02 2BA ? N/A Q8Y8A3 32843560
    67 6yja:A (1.7) BS01 2BA ? N/A O31698 N/A
    68 6yja:B (1.7) BS01 2BA ? N/A O31698 N/A
    69 6z15:A (2.5) BS01 2BA ? GO:0002218 ... Q86WV6 33616279 BindingDB: EC50=200nM
    70 6zza:A (2.491) BS01 2BA ? N/A A0A076YWK5 N/A
    71 7agv:A (1.85) BS02 2BA ? GO:0005886 ... O07535 33790011
    72 7agv:B (1.85) BS01 2BA ? GO:0005886 ... O07535 33790011
    73 7agv:C (1.85) BS01 2BA ? GO:0005886 ... O07535 33790011
    74 7agv:D (1.85) BS01 2BA ? GO:0005886 ... O07535 33790011
    75 7agv:E (1.85) BS01 2BA ? GO:0005886 ... O07535 33790011
    76 7agv:F (1.85) BS01 2BA ? GO:0005886 ... O07535 33790011
    77 7agv:G (1.85) BS02 2BA ? GO:0005886 ... O07535 33790011
    78 7agv:H (1.85) BS01 2BA ? GO:0005886 ... O07535 33790011
    79 7ahe:C (4.1) BS01 2BA 7.6.2.9 GO:0005524 ... Q9KIF7 33208376
    80 7ahe:D (4.1) BS01 2BA 7.6.2.9 GO:0005524 ... Q9KIF7 33208376
    81 7ahh:C (3.5) BS02 2BA 7.6.2.9 GO:0005524 ... Q9KIF7 33208376
    82 7ahh:D (3.5) BS02 2BA 7.6.2.9 GO:0005524 ... Q9KIF7 33208376
    83 7ahm:A (3.14) BS01 2BA ? GO:0005886 ... O07535 33790011
    84 7ahm:B (3.14) BS01 2BA ? GO:0005886 ... O07535 33790011
    85 7ahm:C (3.14) BS01 2BA ? GO:0005886 ... O07535 33790011
    86 7ahm:D (3.14) BS01 2BA ? GO:0005886 ... O07535 33790011
    87 7b5u:A (1.2) BS01 2BA ? GO:0006813 ... K0JNC6 34432045
    88 7b5u:B (1.2) BS01 2BA ? GO:0006813 ... K0JNC6 34432045
    89 7b5y:A (7.1) BS03 2BA ? GO:0003700 ... K0JNC6 34432045
    90 7b5y:B (7.1) BS03 2BA ? GO:0003700 ... K0JNC6 34432045
    91 7b5y:C (7.1) BS02 2BA ? GO:0003700 ... K0JNC6 34432045
    92 7b5y:D (7.1) BS01 2BA ? GO:0003700 ... K0JNC6 34432045
    93 7ji4:A (2.3) BS01 2BA 2.7.13.3 N/A Q2FWH7 33989637
    94 7obj:A (2.0) BS01 2BA ? GO:0005886 ... P73954 34878830
    95 7obj:A (2.0) BS02 2BA ? GO:0005886 ... P73954 34878830
    96 7obj:B (2.0) BS01 2BA ? GO:0005886 ... P73954 34878830
    97 7obj:C (2.0) BS01 2BA ? GO:0005886 ... P73954 34878830
    98 7oz3:A (4.46) BS03 2BA ? GO:0003700 ... K0JNC6 34432045
    99 7oz3:B (4.46) BS03 2BA ? GO:0003700 ... K0JNC6 34432045
    100 7oz3:C (4.46) BS02 2BA ? GO:0003700 ... K0JNC6 34432045
    101 7oz3:D (4.46) BS01 2BA ? GO:0003700 ... K0JNC6 34432045
    102 7xq0:A (3.0) BS01 2BA ? GO:0005886 ... P41440 36265513
    103 7xq0:A (3.0) BS02 2BA ? GO:0005886 ... P41440 36265513
    104 7zz8:A (3.29) BS06 2BA N/A GO:0003824 ... N/A 36261450
    105 7zz8:B (3.29) BS06 2BA N/A GO:0003824 ... N/A 36261450
    106 7zz8:C (3.29) BS02 2BA N/A GO:0003824 ... N/A 36261450
    107 7zz8:D (3.29) BS01 2BA N/A GO:0003824 ... N/A 36261450
    108 8ad6:A (1.52) BS01 2BA ? N/A O31698 N/A
    109 8ad6:B (1.52) BS01 2BA ? N/A O31698 N/A
    110 8b70:A (3.3) BS01 2BA ? GO:0005886 ... P96589 37344476
    111 8b70:B (3.3) BS01 2BA ? GO:0005886 ... P96589 37344476
    112 8b70:B (3.3) BS02 2BA ? GO:0005886 ... P96589 37344476
    113 8b71:A (3.8) BS01 2BA ? GO:0005886 ... P96589 37344476
    114 8b71:A (3.8) BS02 2BA ? GO:0005886 ... P96589 37344476
    115 8b71:B (3.8) BS01 2BA ? GO:0005886 ... P96589 37344476
    116 8b71:B (3.8) BS02 2BA ? GO:0005886 ... P96589 37344476
    117 8h39:A (2.01) BS01 2BA ? GO:0000166 ... A0A1C8HPQ3 36750095
    118 8h39:B (2.01) BS01 2BA ? GO:0000166 ... A0A1C8HPQ3 36750095
    119 8h39:C (2.01) BS01 2BA ? GO:0000166 ... A0A1C8HPQ3 36750095
    120 8h39:D (2.01) BS01 2BA ? GO:0000166 ... A0A1C8HPQ3 36750095
    121 8h39:E (2.01) BS01 2BA ? GO:0000166 ... A0A1C8HPQ3 36750095
    122 8h39:F (2.01) BS01 2BA ? GO:0000166 ... A0A1C8HPQ3 36750095
    123 8hwj:A (2.553) BS01 2BA 3.2.2.5 N/A A0A085BE66 38129386
    124 8hwj:B (2.553) BS01 2BA 3.2.2.5 N/A A0A085BE66 38129386
    125 8hwj:C (2.553) BS01 2BA 3.2.2.5 N/A A0A085BE66 38129386
    126 8hwj:D (2.553) BS01 2BA 3.2.2.5 N/A A0A085BE66 38129386
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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