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BioLiP
Download all results in tab-seperated text for 23 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1wdy:A (1.8) BS01 25A 3.1.26.- N/A Q05823 15385955 PDBbind: -logKd/Ki=7.89, IC50=13nM
    BindingDB: IC50=20nM, EC50=0.210000nM
    2 3pwk:A (1.5) BS01 25A N/A GO:0004073 ... N/A 22039970
    3 3pwk:B (1.5) BS01 25A N/A GO:0004073 ... N/A 22039970
    4 4g8l:A (2.8) BS01 25A 3.1.26.- N/A Q05823 23084743 PDBbind: -logKd/Ki=8.00, Kd=10nM
    BindingDB: IC50=20nM, EC50=0.210000nM
    5 4g8l:A (2.8) BS02 25A 3.1.26.- N/A Q05823 23084743 PDBbind: -logKd/Ki=8.00, Kd=10nM
    BindingDB: IC50=20nM, EC50=0.210000nM
    6 4g8l:B (2.8) BS01 25A 3.1.26.- N/A Q05823 23084743 BindingDB: IC50=20nM, EC50=0.210000nM
    7 4g8l:B (2.8) BS02 25A 3.1.26.- N/A Q05823 23084743 BindingDB: IC50=20nM, EC50=0.210000nM
    8 4g8l:C (2.8) BS01 25A 3.1.26.- N/A Q05823 23084743 BindingDB: IC50=20nM, EC50=0.210000nM
    9 4g8l:C (2.8) BS02 25A 3.1.26.- N/A Q05823 23084743 BindingDB: IC50=20nM, EC50=0.210000nM
    10 4g8l:D (2.8) BS01 25A 3.1.26.- N/A Q05823 23084743 BindingDB: IC50=20nM, EC50=0.210000nM
    11 4g8l:D (2.8) BS02 25A 3.1.26.- N/A Q05823 23084743 BindingDB: IC50=20nM, EC50=0.210000nM
    12 6m11:a (2.46) BS01 25A ? GO:0004540 ... A5H025 32830849
    13 6m11:a (2.46) BS03 25A ? GO:0004540 ... A5H025 32830849
    14 6m11:b (2.46) BS01 25A ? GO:0004540 ... A5H025 32830849
    15 6m11:b (2.46) BS02 25A ? GO:0004540 ... A5H025 32830849
    16 7dsy:a (2.651) BS01 25A ? GO:0004540 ... A5H025 N/A
    17 7dsy:a (2.651) BS03 25A ? GO:0004540 ... A5H025 N/A
    18 7dsy:b (2.651) BS01 25A ? GO:0004540 ... A5H025 N/A
    19 7dsy:b (2.651) BS02 25A ? GO:0004540 ... A5H025 N/A
    20 7dts:a (2.63) BS01 25A ? GO:0004540 ... A5H025 N/A
    21 7dts:a (2.63) BS03 25A ? GO:0004540 ... A5H025 N/A
    22 7dts:b (2.63) BS01 25A ? GO:0004540 ... A5H025 N/A
    23 7dts:b (2.63) BS02 25A ? GO:0004540 ... A5H025 N/A
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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