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BioLiP
Download all results in tab-seperated text for 21 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 2bxe:A (2.95) BS01 1FL ? GO:0003677 ... P02768 16169013 BindingDB: Kd=1230nM, Ki=58884365535559nM
    2 2bxe:A (2.95) BS02 1FL ? GO:0003677 ... P02768 16169013 BindingDB: Kd=1230nM, Ki=58884365535559nM
    3 2bxe:A (2.95) BS03 1FL ? GO:0003677 ... P02768 16169013 BindingDB: Kd=1230nM, Ki=58884365535559nM
    4 2bxe:B (2.95) BS01 1FL ? GO:0003677 ... P02768 16169013 BindingDB: Kd=1230nM, Ki=58884365535559nM
    5 2bxe:B (2.95) BS02 1FL ? GO:0003677 ... P02768 16169013 BindingDB: Kd=1230nM, Ki=58884365535559nM
    6 2bxe:B (2.95) BS03 1FL ? GO:0003677 ... P02768 16169013 BindingDB: Kd=1230nM, Ki=58884365535559nM
    7 3d2t:A (1.85) BS01 1FL ? GO:0005179 ... P02766 14711308 MOAD: Kd=75nM
    PDBbind: -logKd/Ki=7.12, Kd=75nM
    BindingDB: IC50=12000nM, Kd=407nM, EC50=5600nM
    8 3d2t:B (1.85) BS01 1FL ? GO:0005179 ... P02766 14711308 MOAD: Kd=75nM
    PDBbind: -logKd/Ki=7.12, Kd=75nM
    BindingDB: IC50=12000nM, Kd=407nM, EC50=5600nM
    9 4i89:A (1.69) BS01 1FL ? GO:0005179 ... P02766 23792159 BindingDB: IC50=12000nM, Kd=407nM, EC50=5600nM
    10 4i89:B (1.69) BS01 1FL ? GO:0005179 ... P02766 23792159 BindingDB: IC50=12000nM, Kd=407nM, EC50=5600nM
    11 5g48:A (2.28) BS01 1FL ? GO:0003677 ... O25242 28656718
    12 5g48:B (2.28) BS01 1FL ? GO:0003677 ... O25242 28656718
    13 6e70:A (1.992) BS01 1FL ? GO:0005179 ... P02766 N/A BindingDB: IC50=12000nM, Kd=407nM, EC50=5600nM
    14 6e70:B (1.992) BS01 1FL ? GO:0005179 ... P02766 N/A BindingDB: IC50=12000nM, Kd=407nM, EC50=5600nM
    15 6e73:A (1.797) BS01 1FL ? GO:0005179 ... P02766 N/A BindingDB: IC50=12000nM, Kd=407nM, EC50=5600nM
    16 6e73:B (1.797) BS01 1FL ? GO:0005179 ... P02766 N/A BindingDB: IC50=12000nM, Kd=407nM, EC50=5600nM
    17 6e78:A (1.499) BS01 1FL ? GO:0005179 ... P02766 N/A BindingDB: IC50=12000nM, Kd=407nM, EC50=5600nM
    18 6e78:B (1.499) BS01 1FL ? GO:0005179 ... P02766 N/A BindingDB: IC50=12000nM, Kd=407nM, EC50=5600nM
    19 7k12:A (2.17) BS02 1FL 4.-.-.- GO:0005737 ... Q83V25 33369426
    20 7ycq:A (1.99) BS01 1FL ? GO:0005179 ... P02766 36851846
    21 7ycq:B (1.99) BS01 1FL ? GO:0005179 ... P02766 36851846
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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