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BioLiP
Download all results in tab-seperated text for 10 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 2f64:A (1.6) BS01 12Q 2.4.2.6 GO:0005634 ... Q57VC7 17004709
    2 2f64:A (1.6) BS02 12Q 2.4.2.6 GO:0005634 ... Q57VC7 17004709
    3 2f64:B (1.6) BS01 12Q 2.4.2.6 GO:0005634 ... Q57VC7 17004709
    4 2f64:B (1.6) BS02 12Q 2.4.2.6 GO:0005634 ... Q57VC7 17004709
    5 4qst:A (2.05) BS01 12Q 3.6.1.- N/A Q6PL18 N/A BindingDB: IC50=>100000nM
    6 5fe1:A (2.22) BS01 12Q 2.3.1.48
    2.3.1.57    		 GO:0004402 ... Q92831 26731131 BindingDB: IC50=70000nM
    7 5fe1:B (2.22) BS01 12Q 2.3.1.48
    2.3.1.57    		 GO:0004402 ... Q92831 26731131 BindingDB: IC50=70000nM
    8 5s8l:A (1.23) BS01 12Q ? N/A Q8WWQ0 N/A
    9 5t4u:A (1.5) BS01 12Q ? N/A P55201 28068087 MOAD: ic50=4800nM
    PDBbind: -logKd/Ki=5.32, IC50=4800nM
    BindingDB: IC50=4800nM
    10 7px5:AAA (2.18) BS01 12Q 3.6.1.- N/A Q6PL18 36322414
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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