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BioLiP
Download all results in tab-seperated text for 18 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 2chz:A (2.6) BS01 093 2.7.11.1
    2.7.1.137
    2.7.1.153
    2.7.1.154    		 GO:0016301 ... P48736 16647110 PDBbind: -logKd/Ki=7.80, IC50=16nM
    BindingDB: IC50=16nM, Ki=7.0nM
    2 2x6j:A (3.5) BS01 093 2.7.1.137 GO:0016301 ... Q9W1M7 20339072 PDBbind: -logKd/Ki=7.44, IC50=36nM
    3 2x6j:B (3.5) BS01 093 2.7.1.137 GO:0016301 ... Q9W1M7 20339072
    4 4d0l:A (2.94) BS01 093 2.7.1.67 GO:0016301 ... Q9UBF8 24876499 BindingDB: IC50=19nM
    5 4d0l:C (2.94) BS01 093 2.7.1.67 GO:0016301 ... Q9UBF8 24876499 BindingDB: IC50=19nM
    6 4d0l:E (2.94) BS01 093 2.7.1.67 GO:0016301 ... Q9UBF8 24876499 BindingDB: IC50=19nM
    7 4d0m:A (6.0) BS01 093 2.7.1.67 GO:0016301 ... Q9UBF8 24876499 BindingDB: IC50=19nM
    8 4d0m:C (6.0) BS01 093 2.7.1.67 GO:0016301 ... Q9UBF8 24876499 BindingDB: IC50=19nM
    9 4d0m:G (6.0) BS01 093 2.7.1.67 GO:0016301 ... Q9UBF8 24876499 BindingDB: IC50=19nM
    10 4d0m:I (6.0) BS01 093 2.7.1.67 GO:0016301 ... Q9UBF8 24876499 BindingDB: IC50=19nM
    11 4d0m:M (6.0) BS01 093 2.7.1.67 GO:0016301 ... Q9UBF8 24876499 BindingDB: IC50=19nM
    12 4d0m:O (6.0) BS01 093 2.7.1.67 GO:0016301 ... Q9UBF8 24876499 BindingDB: IC50=19nM
    13 4d0m:Q (6.0) BS01 093 2.7.1.67 GO:0016301 ... Q9UBF8 24876499 BindingDB: IC50=19nM
    14 4d0m:S (6.0) BS01 093 2.7.1.67 GO:0016301 ... Q9UBF8 24876499 BindingDB: IC50=19nM
    15 4d0m:W (6.0) BS01 093 2.7.1.67 GO:0016301 ... Q9UBF8 24876499 BindingDB: IC50=19nM
    16 4d0m:Y (6.0) BS01 093 2.7.1.67 GO:0016301 ... Q9UBF8 24876499 BindingDB: IC50=19nM
    17 4d0m:c (6.0) BS01 093 2.7.1.67 GO:0016301 ... Q9UBF8 24876499 BindingDB: IC50=19nM
    18 4d0m:g (6.0) BS01 093 2.7.1.67 GO:0016301 ... Q9UBF8 24876499 BindingDB: IC50=19nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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