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BioLiP
Download all results in tab-seperated text for 713946 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    10401 1flo:D (2.65) BS03 dna ? GO:0003677 ... P03870 11090626
    10402 1flo:D (2.65) BS04 PHS ? GO:0003677 ... P03870 11090626
    10403 1flp:A (1.5) BS01 HEM ? GO:0005576 ... P41260 7966324
    10404 1fls:A (-1.00) BS01 ZN 3.4.24.- GO:0004222 ... P45452 10986126
    10405 1fls:A (-1.00) BS02 ZN 3.4.24.- GO:0004222 ... P45452 10986126
    10406 1fls:A (-1.00) BS03 CA 3.4.24.- GO:0004222 ... P45452 10986126
    10407 1fls:A (-1.00) BS04 WAY 3.4.24.- GO:0004222 ... P45452 10986126 PDBbind: -logKd/Ki=7.48, IC50=33nM
    BindingDB: IC50=8nM
    10408 1flz:A (2.3) BS01 URA 3.2.2.27 GO:0004844 ... P12295 11027138
    10409 1fm1:A (-1.00) BS01 ZN 3.4.24.- GO:0004222 ... P45452 10986126
    10410 1fm1:A (-1.00) BS02 ZN 3.4.24.- GO:0004222 ... P45452 10986126
    10411 1fm1:A (-1.00) BS03 CA 3.4.24.- GO:0004222 ... P45452 10986126
    10412 1fm1:A (-1.00) BS04 WAY 3.4.24.- GO:0004222 ... P45452 10986126 BindingDB: IC50=8nM
    10413 1fm4:A (1.97) BS01 DXC ? GO:0004864 ... P43185 12473456
    10414 1fm4:A (1.97) BS02 DXC ? GO:0004864 ... P43185 12473456
    10415 1fm6:A (2.1) BS01 peptide ? GO:0003677 ... P19793 10882139
    10416 1fm6:A (2.1) BS02 9CR ? GO:0003677 ... P19793 10882139 BindingDB: EC50=100nM, Ki=583nM, IC50=32nM, Kd=240nM
    10417 1fm6:D (2.1) BS01 peptide ? GO:0003677 ... P37231 10882139
    10418 1fm6:D (2.1) BS02 BRL ? GO:0003677 ... P37231 10882139 BindingDB: EC50=40nM, IC50=1.000000nM, Ki=8nM, Kd=0.145000nM
    10419 1fm6:U (2.1) BS01 peptide ? GO:0003677 ... P19793 10882139
    10420 1fm6:U (2.1) BS02 9CR ? GO:0003677 ... P19793 10882139 BindingDB: EC50=100nM, Ki=583nM, IC50=32nM, Kd=240nM
    10421 1fm6:X (2.1) BS01 peptide ? GO:0003677 ... P37231 10882139
    10422 1fm6:X (2.1) BS02 BRL ? GO:0003677 ... P37231 10882139 BindingDB: EC50=40nM, IC50=1.000000nM, Ki=8nM, Kd=0.145000nM
    10423 1fm7:A (2.3) BS01 DFV 5.5.1.6 GO:0009813 ... P28012 11698411
    10424 1fm7:B (2.3) BS01 DFV 5.5.1.6 GO:0009813 ... P28012 11698411
    10425 1fm8:A (2.3) BS01 DDC 5.5.1.6 GO:0009813 ... P28012 11698411
    10426 1fm9:A (2.1) BS01 peptide ? GO:0003677 ... P19793 10882139
    10427 1fm9:A (2.1) BS02 9CR ? GO:0003677 ... P19793 10882139 BindingDB: EC50=100nM, Ki=583nM, IC50=32nM, Kd=240nM
    10428 1fm9:D (2.1) BS01 peptide ? GO:0003677 ... P37231 10882139
    10429 1fm9:D (2.1) BS02 570 ? GO:0003677 ... P37231 10882139 MOAD: Ki=1nM
    PDBbind: -logKd/Ki=9.00, Ki=1nM
    BindingDB: Ki=1.1nM, EC50=0.338844nM, IC50=25nM
    10430 1fmb:A (1.8) BS01 HYB 2.7.7.-
    2.7.7.49
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.-
    GO:0004190 ... P32542 8844837 MOAD: Ki=0.1nM
    PDBbind: -logKd/Ki=10.00, Ki=0.1nM
    10431 1fmc:A (1.8) BS01 CHO 1.1.1.159 GO:0005829 ... P0AET8 8672472
    10432 1fmc:A (1.8) BS02 NAI 1.1.1.159 GO:0005829 ... P0AET8 8672472
    10433 1fmc:B (1.8) BS01 CHO 1.1.1.159 GO:0005829 ... P0AET8 8672472
    10434 1fmc:B (1.8) BS02 NAI 1.1.1.159 GO:0005829 ... P0AET8 8672472
    10435 1fmg:A (1.9) BS01 CA 3.4.21.4 GO:0004252 ... P00761 11679713
    10436 1fmj:A (2.0) BS01 CA ? GO:0005737 ... Q26490 11323722
    10437 1fmj:A (2.0) BS02 A3P ? GO:0005737 ... Q26490 11323722
    10438 1fmj:A (2.0) BS03 RTL ? GO:0005737 ... Q26490 11323722
    10439 1fmj:B (2.0) BS01 CA ? GO:0005737 ... Q26490 11323722
    10440 1fmj:B (2.0) BS02 A3P ? GO:0005737 ... Q26490 11323722
    10441 1fmj:B (2.0) BS03 RTL ? GO:0005737 ... Q26490 11323722
    10442 1fml:A (2.75) BS01 CA ? GO:0005737 ... Q26490 11323722
    10443 1fml:A (2.75) BS02 A3P ? GO:0005737 ... Q26490 11323722
    10444 1fml:A (2.75) BS03 RTL ? GO:0005737 ... Q26490 11323722
    10445 1fml:B (2.75) BS01 CA ? GO:0005737 ... Q26490 11323722
    10446 1fml:B (2.75) BS02 A3P ? GO:0005737 ... Q26490 11323722
    10447 1fml:B (2.75) BS03 RTL ? GO:0005737 ... Q26490 11323722
    10448 1fmo:E (2.2) BS01 peptide 2.7.11.11 GO:0000122 ... P05132 9109651
    10449 1fmo:E (2.2) BS02 ADN 2.7.11.11 GO:0000122 ... P05132 9109651 MOAD: Ki=2.3nM
    10450 1fmu:A (2.7) BS01 MAN 3.4.23.25 GO:0000324 ... P07267 12127998
    10451 1fn3:A (2.48) BS01 HNI ? GO:0004601 ... P69905 N/A
    10452 1fn3:B (2.48) BS01 HNI ? GO:0004601 ... P68871 N/A
    10453 1fn3:C (2.48) BS01 HNI ? GO:0004601 ... P69905 N/A
    10454 1fn3:D (2.48) BS01 HNI ? GO:0004601 ... P68871 N/A
    10455 1fn6:A (1.8) BS01 CA 3.4.21.4 GO:0004252 ... P00761 11679713
    10456 1fn7:A (2.6) BS01 dna 3.2.2.-
    4.2.99.18
    GO:0000978 ... O15527 11456534
    10457 1fn7:A (2.6) BS02 dna 3.2.2.-
    4.2.99.18
    GO:0000978 ... O15527 11456534
    10458 1fn8:A (0.81) BS01 peptide 3.4.21.4 GO:0004252 ... P35049 11134922
    10459 1fn9:A (1.8) BS01 ZN ? GO:0003723 ... P03527 11230122
    10460 1fn9:B (1.8) BS01 ZN ? GO:0003723 ... P03527 11230122
    10461 1fni:A (1.6) BS01 CA 3.4.21.4 GO:0004252 ... P00761 11679713
    10462 1fnm:A (2.8) BS01 GDP ? GO:0000287 ... P13551 11054294
    10463 1fnn:A (2.0) BS01 ADP ? GO:0005524 ... Q8ZYK1 11030343
    10464 1fnn:B (2.0) BS01 ADP ? GO:0005524 ... Q8ZYK1 11030343
    10465 1fno:A (2.4) BS01 ZN 3.4.11.4 GO:0004177 ... P26311 11856302
    10466 1fno:A (2.4) BS02 ZN 3.4.11.4 GO:0004177 ... P26311 11856302
    10467 1fnp:L (2.6) BS01 BCL ? GO:0009772 ... P0C0Y8 11284681
    10468 1fnp:L (2.6) BS02 BCL ? GO:0009772 ... P0C0Y8 11284681
    10469 1fnp:L (2.6) BS03 BPH ? GO:0009772 ... P0C0Y8 11284681
    10470 1fnp:L (2.6) BS04 U10 ? GO:0009772 ... P0C0Y8 11284681
    10471 1fnp:L (2.6) BS05 FE ? GO:0009772 ... P0C0Y8 11284681
    10472 1fnp:L (2.6) BS06 BCL ? GO:0009772 ... P0C0Y8 11284681
    10473 1fnp:L (2.6) BS07 BPH ? GO:0009772 ... P0C0Y8 11284681
    10474 1fnp:M (2.6) BS01 BCL ? GO:0009772 ... P0C0Y9 11284681
    10475 1fnp:M (2.6) BS02 BPH ? GO:0009772 ... P0C0Y9 11284681
    10476 1fnp:M (2.6) BS03 FE ? GO:0009772 ... P0C0Y9 11284681
    10477 1fnp:M (2.6) BS04 BCL ? GO:0009772 ... P0C0Y9 11284681
    10478 1fnp:M (2.6) BS05 BCL ? GO:0009772 ... P0C0Y9 11284681
    10479 1fnp:M (2.6) BS06 BPH ? GO:0009772 ... P0C0Y9 11284681
    10480 1fnp:M (2.6) BS07 U10 ? GO:0009772 ... P0C0Y9 11284681
    10481 1fnp:M (2.6) BS08 SPO ? GO:0009772 ... P0C0Y9 11284681
    10482 1fnq:L (2.6) BS01 BCL ? GO:0009772 ... P0C0Y8 11284681
    10483 1fnq:L (2.6) BS02 BCL ? GO:0009772 ... P0C0Y8 11284681
    10484 1fnq:L (2.6) BS03 BPH ? GO:0009772 ... P0C0Y8 11284681
    10485 1fnq:L (2.6) BS04 U10 ? GO:0009772 ... P0C0Y8 11284681
    10486 1fnq:L (2.6) BS05 FE ? GO:0009772 ... P0C0Y8 11284681
    10487 1fnq:L (2.6) BS06 BCL ? GO:0009772 ... P0C0Y8 11284681
    10488 1fnq:L (2.6) BS07 BPH ? GO:0009772 ... P0C0Y8 11284681
    10489 1fnq:L (2.6) BS08 U10 ? GO:0009772 ... P0C0Y8 11284681
    10490 1fnq:M (2.6) BS01 BCL ? GO:0009772 ... P0C0Y9 11284681
    10491 1fnq:M (2.6) BS02 BPH ? GO:0009772 ... P0C0Y9 11284681
    10492 1fnq:M (2.6) BS03 FE ? GO:0009772 ... P0C0Y9 11284681
    10493 1fnq:M (2.6) BS04 BCL ? GO:0009772 ... P0C0Y9 11284681
    10494 1fnq:M (2.6) BS05 BCL ? GO:0009772 ... P0C0Y9 11284681
    10495 1fnq:M (2.6) BS06 BPH ? GO:0009772 ... P0C0Y9 11284681
    10496 1fnq:M (2.6) BS07 U10 ? GO:0009772 ... P0C0Y9 11284681
    10497 1fnq:M (2.6) BS08 SPO ? GO:0009772 ... P0C0Y9 11284681
    10498 1fnt:H (3.2) BS01 MG 3.4.25.1 GO:0000502 ... P38624 11081519
    10499 1fnt:I (3.2) BS01 MG 3.4.25.1 GO:0004298 ... P25043 11081519
    10500 1fnt:J (3.2) BS01 MG 3.4.99.46 GO:0000502 ... P25451 11081519
    10501 1fnt:L (3.2) BS01 MG 3.4.25.1 GO:0004298 ... P30656 11081519
    10502 1fnt:V (3.2) BS01 MG 3.4.25.1 GO:0000502 ... P38624 11081519
    10503 1fnt:W (3.2) BS01 MG 3.4.25.1 GO:0004298 ... P25043 11081519
    10504 1fnt:X (3.2) BS01 MG 3.4.99.46 GO:0000502 ... P25451 11081519
    10505 1fnt:Z (3.2) BS01 MG 3.4.25.1 GO:0004298 ... P30656 11081519
    10506 1fnt:a (3.2) BS01 MG 3.4.99.46 GO:0000502 ... P23724 11081519
    10507 1fo0:B (2.5) BS01 peptide ? GO:0002250 ... P04214 11017099
    10508 1fo2:A (2.38) BS01 DMJ 3.2.1.113 GO:0004571 ... Q9UKM7 10995765 MOAD: ic50=20uM
    PDBbind: -logKd/Ki=4.70, IC50=20uM
    10509 1fo3:A (1.75) BS01 KIF 3.2.1.113 GO:0004571 ... Q9UKM7 10995765 MOAD: ic50=0.2uM
    PDBbind: -logKd/Ki=6.70, IC50=0.2uM
    10510 1fo4:A (2.1) BS01 CA 1.17.1.4
    1.17.3.2
    GO:0002197 ... P80457 11005854
    10511 1fo4:A (2.1) BS02 FES 1.17.1.4
    1.17.3.2
    GO:0002197 ... P80457 11005854
    10512 1fo4:A (2.1) BS03 FES 1.17.1.4
    1.17.3.2
    GO:0002197 ... P80457 11005854
    10513 1fo4:A (2.1) BS04 FAD 1.17.1.4
    1.17.3.2
    GO:0002197 ... P80457 11005854
    10514 1fo4:B (2.1) BS01 CA 1.17.1.4
    1.17.3.2
    GO:0002197 ... P80457 11005854
    10515 1fo4:B (2.1) BS02 FES 1.17.1.4
    1.17.3.2
    GO:0002197 ... P80457 11005854
    10516 1fo4:B (2.1) BS03 FES 1.17.1.4
    1.17.3.2
    GO:0002197 ... P80457 11005854
    10517 1fo4:B (2.1) BS04 FAD 1.17.1.4
    1.17.3.2
    GO:0002197 ... P80457 11005854
    10518 1foa:A (1.8) BS01 UD1 2.4.1.101 GO:0006486 ... P27115 11032794
    10519 1fof:A (2.0) BS01 CO 3.5.2.6 GO:0008658 ... P14489 11017203
    10520 1fof:B (2.0) BS01 CO 3.5.2.6 GO:0008658 ... P14489 11017203
    10521 1foh:A (2.4) BS01 FAD 1.14.13.7 GO:0004497 ... P15245 9634698
    10522 1foh:A (2.4) BS02 IPH 1.14.13.7 GO:0004497 ... P15245 9634698
    10523 1foh:B (2.4) BS01 FAD 1.14.13.7 GO:0004497 ... P15245 9634698
    10524 1foh:B (2.4) BS02 IPH 1.14.13.7 GO:0004497 ... P15245 9634698
    10525 1foh:C (2.4) BS01 FAD 1.14.13.7 GO:0004497 ... P15245 9634698
    10526 1foh:C (2.4) BS02 IPH 1.14.13.7 GO:0004497 ... P15245 9634698
    10527 1foh:D (2.4) BS01 FAD 1.14.13.7 GO:0004497 ... P15245 9634698
    10528 1foh:D (2.4) BS02 IPH 1.14.13.7 GO:0004497 ... P15245 9634698
    10529 1foi:A (1.93) BS01 ZN 1.14.13.39 GO:0004517 ... P29473 11331003
    10530 1foi:A (1.93) BS02 HEM 1.14.13.39 GO:0004517 ... P29473 11331003
    10531 1foi:A (1.93) BS03 14W 1.14.13.39 GO:0004517 ... P29473 11331003
    10532 1foi:B (1.93) BS01 ZN 1.14.13.39 GO:0004517 ... P29473 11331003
    10533 1foi:B (1.93) BS02 HEM 1.14.13.39 GO:0004517 ... P29473 11331003
    10534 1foi:B (1.93) BS03 14W 1.14.13.39 GO:0004517 ... P29473 11331003
    10535 1foj:A (2.1) BS01 ZN 1.14.13.39 GO:0004517 ... P29473 11695891
    10536 1foj:A (2.1) BS02 HEM 1.14.13.39 GO:0004517 ... P29473 11695891
    10537 1foj:A (2.1) BS03 7NI 1.14.13.39 GO:0004517 ... P29473 11695891 BindingDB: IC50=35000nM
    10538 1foj:A (2.1) BS04 7I2 1.14.13.39 GO:0004517 ... P29473 11695891
    10539 1foj:A (2.1) BS05 7I2 1.14.13.39 GO:0004517 ... P29473 11695891
    10540 1foj:B (2.1) BS01 ZN 1.14.13.39 GO:0004517 ... P29473 11695891
    10541 1foj:B (2.1) BS02 HEM 1.14.13.39 GO:0004517 ... P29473 11695891
    10542 1foj:B (2.1) BS03 7NI 1.14.13.39 GO:0004517 ... P29473 11695891 BindingDB: IC50=35000nM
    10543 1foj:B (2.1) BS04 7I2 1.14.13.39 GO:0004517 ... P29473 11695891
    10544 1foj:B (2.1) BS05 7I2 1.14.13.39 GO:0004517 ... P29473 11695891
    10545 1fok:A (2.8) BS01 dna 3.1.21.4 GO:0003677 ... P14870 9214510
    10546 1fok:A (2.8) BS02 dna 3.1.21.4 GO:0003677 ... P14870 9214510
    10547 1fol:A (2.2) BS01 HEM 1.14.13.39 GO:0004517 ... P29473 11331003
    10548 1fol:A (2.2) BS02 ARG 1.14.13.39 GO:0004517 ... P29473 11331003
    10549 1fol:B (2.2) BS01 ZN 1.14.13.39 GO:0004517 ... P29473 11331003
    10550 1fol:B (2.2) BS02 HEM 1.14.13.39 GO:0004517 ... P29473 11331003
    10551 1fol:B (2.2) BS03 ARG 1.14.13.39 GO:0004517 ... P29473 11331003
    10552 1foo:A (2.0) BS01 ZN 1.14.13.39 GO:0004517 ... P29473 11331003
    10553 1foo:A (2.0) BS02 HEM 1.14.13.39 GO:0004517 ... P29473 11331003
    10554 1foo:A (2.0) BS03 ARG 1.14.13.39 GO:0004517 ... P29473 11331003
    10555 1foo:B (2.0) BS01 ZN 1.14.13.39 GO:0004517 ... P29473 11331003
    10556 1foo:B (2.0) BS02 HEM 1.14.13.39 GO:0004517 ... P29473 11331003
    10557 1foo:B (2.0) BS03 ARG 1.14.13.39 GO:0004517 ... P29473 11331003
    10558 1fop:A (2.3) BS01 HEM 1.14.13.39 GO:0004517 ... P29473 11331003
    10559 1fop:A (2.3) BS02 H4B 1.14.13.39 GO:0004517 ... P29473 11331003
    10560 1fop:A (2.3) BS03 ARG 1.14.13.39 GO:0004517 ... P29473 11331003
    10561 1fop:A (2.3) BS04 ZN 1.14.13.39 GO:0004517 ... P29473 11331003
    10562 1fop:A (2.3) BS05 H4B 1.14.13.39 GO:0004517 ... P29473 11331003
    10563 1fop:B (2.3) BS01 H4B 1.14.13.39 GO:0004517 ... P29473 11331003
    10564 1fop:B (2.3) BS02 ZN 1.14.13.39 GO:0004517 ... P29473 11331003
    10565 1fop:B (2.3) BS03 HEM 1.14.13.39 GO:0004517 ... P29473 11331003
    10566 1fop:B (2.3) BS04 H4B 1.14.13.39 GO:0004517 ... P29473 11331003
    10567 1fop:B (2.3) BS05 ARG 1.14.13.39 GO:0004517 ... P29473 11331003
    10568 1fos:E (3.05) BS01 dna ? GO:0003677 ... P01100 7816143
    10569 1fos:E (3.05) BS02 dna ? GO:0003677 ... P01100 7816143
    10570 1fos:F (3.05) BS01 dna ? GO:0003677 ... P05412 7816143
    10571 1fos:G (3.05) BS01 dna ? GO:0003677 ... P01100 7816143
    10572 1fos:H (3.05) BS01 dna ? GO:0003677 ... P05412 7816143
    10573 1fos:H (3.05) BS02 dna ? GO:0003677 ... P05412 7816143
    10574 1fp1:D (1.82) BS01 SAH 2.1.1.154
    2.1.1.65
    GO:0008168 ... P93324 11224575
    10575 1fp1:D (1.82) BS02 HCC 2.1.1.154
    2.1.1.65
    GO:0008168 ... P93324 11224575
    10576 1fp2:A (1.4) BS01 SAH 2.1.1.150 GO:0008168 ... O24529 11224575
    10577 1fp2:A (1.4) BS02 HMO 2.1.1.150 GO:0008168 ... O24529 11224575
    10578 1fp4:A (2.5) BS01 CFM 1.18.6.1 GO:0005524 ... P07328 11327812
    10579 1fp4:A (2.5) BS02 CLP 1.18.6.1 GO:0005524 ... P07328 11327812
    10580 1fp4:B (2.5) BS01 CLP 1.18.6.1 GO:0005524 ... P07329 11327812
    10581 1fp4:B (2.5) BS02 CA 1.18.6.1 GO:0005524 ... P07329 11327812
    10582 1fp4:B (2.5) BS03 CA 1.18.6.1 GO:0005524 ... P07329 11327812
    10583 1fp4:C (2.5) BS01 CFM 1.18.6.1 GO:0005524 ... P07328 11327812
    10584 1fp4:C (2.5) BS02 CLP 1.18.6.1 GO:0005524 ... P07328 11327812
    10585 1fp4:D (2.5) BS01 CA 1.18.6.1 GO:0005524 ... P07329 11327812
    10586 1fp4:D (2.5) BS02 CLP 1.18.6.1 GO:0005524 ... P07329 11327812
    10587 1fp4:D (2.5) BS03 CA 1.18.6.1 GO:0005524 ... P07329 11327812
    10588 1fp6:A (2.15) BS01 SF4 1.18.6.1 GO:0005524 ... P00459 11101289
    10589 1fp6:A (2.15) BS02 ADP 1.18.6.1 GO:0005524 ... P00459 11101289
    10590 1fp6:B (2.15) BS01 SF4 1.18.6.1 GO:0005524 ... P00459 11101289
    10591 1fp6:B (2.15) BS02 ADP 1.18.6.1 GO:0005524 ... P00459 11101289
    10592 1fp6:C (2.15) BS01 SF4 1.18.6.1 GO:0005524 ... P00459 11101289
    10593 1fp6:C (2.15) BS02 ADP 1.18.6.1 GO:0005524 ... P00459 11101289
    10594 1fp6:D (2.15) BS01 SF4 1.18.6.1 GO:0005524 ... P00459 11101289
    10595 1fp6:D (2.15) BS02 ADP 1.18.6.1 GO:0005524 ... P00459 11101289
    10596 1fp7:A (3.2) BS01 K 6.3.4.3 GO:0004329 ... P21164 11087401
    10597 1fpb:A (2.6) BS01 FDP 3.1.3.11 GO:0005737 ... P00636 1312721
    10598 1fpb:A (2.6) BS02 FDP 3.1.3.11 GO:0005737 ... P00636 1312721
    10599 1fpb:B (2.6) BS01 FDP 3.1.3.11 GO:0005737 ... P00636 1312721
    10600 1fpc:H (2.3) BS01 peptide 3.4.21.5 GO:0004252 ... P00734 15299843

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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