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BioLiP
Download all results in tab-seperated text for 594392 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    13801 1ir2:S (1.84) BS01 MG 4.1.1.39 GO:0000287 ... P00877 11866526
    13802 1ir2:S (1.84) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    13803 1ir2:S (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    13804 1ir2:T (1.84) BS01 MG 4.1.1.39 GO:0000287 ... P00877 11866526
    13805 1ir2:T (1.84) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    13806 1ir2:T (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    13807 1ir2:U (1.84) BS01 MG 4.1.1.39 GO:0000287 ... P00877 11866526
    13808 1ir2:U (1.84) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    13809 1ir2:U (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    13810 1ir2:V (1.84) BS01 MG 4.1.1.39 GO:0000287 ... P00877 11866526
    13811 1ir2:V (1.84) BS02 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    13812 1ir2:V (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    13813 1ir2:W (1.84) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    13814 1ir2:W (1.84) BS02 MG 4.1.1.39 GO:0000287 ... P00877 11866526
    13815 1ir2:W (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    13816 1ir2:X (1.84) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    13817 1ir2:X (1.84) BS02 MG 4.1.1.39 GO:0000287 ... P00877 11866526
    13818 1ir2:X (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    13819 1ir2:Y (1.84) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    13820 1ir2:Y (1.84) BS02 MG 4.1.1.39 GO:0000287 ... P00877 11866526
    13821 1ir2:Y (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    13822 1ir2:Z (1.84) BS01 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    13823 1ir2:Z (1.84) BS02 MG 4.1.1.39 GO:0000287 ... P00877 11866526
    13824 1ir2:Z (1.84) BS03 CAP 4.1.1.39 GO:0000287 ... P00877 11866526
    13825 1ir3:A (1.9) BS01 peptide 2.7.10.1 GO:0004672 ... P06213 9312016
    13826 1ir3:A (1.9) BS02 MG 2.7.10.1 GO:0004672 ... P06213 9312016
    13827 1ir3:A (1.9) BS03 ANP 2.7.10.1 GO:0004672 ... P06213 9312016
    13828 1irb:A (1.9) BS01 CA 3.1.1.4 GO:0002227 ... P00593 8810924
    13829 1irc:A (2.17) BS01 HEM 1.11.1.-
    1.7.-.-
    GO:0004601 ... P02185 8204590
    13830 1irc:A (2.17) BS02 IMD 1.11.1.-
    1.7.-.-
    GO:0004601 ... P02185 8204590
    13831 1ird:A (1.25) BS01 HEM ? GO:0004601 ... P69905 N/A
    13832 1ird:B (1.25) BS01 HEM ? GO:0004601 ... P68871 N/A
    13833 1ire:A (1.8) BS01 CO 4.2.1.84 GO:0003824 ... Q7SID2 11700034
    13834 1iri:A (2.4) BS01 E4P 5.3.1.9 GO:0001701 ... P06744 12054796
    13835 1iri:B (2.4) BS01 E4P 5.3.1.9 GO:0001701 ... P06744 12054796
    13836 1iri:C (2.4) BS01 E4P 5.3.1.9 GO:0001701 ... P06744 12054796
    13837 1iri:D (2.4) BS01 E4P 5.3.1.9 GO:0001701 ... P06744 12054796
    13838 1irj:A (2.1) BS01 CA ? GO:0002523 ... P06702 11851337
    13839 1irj:A (2.1) BS02 CA ? GO:0002523 ... P06702 11851337
    13840 1irj:B (2.1) BS01 CA ? GO:0002523 ... P06702 11851337
    13841 1irj:B (2.1) BS02 CA ? GO:0002523 ... P06702 11851337
    13842 1irj:B (2.1) BS03 CPS ? GO:0002523 ... P06702 11851337
    13843 1irj:C (2.1) BS01 CA ? GO:0002523 ... P06702 11851337
    13844 1irj:C (2.1) BS02 CA ? GO:0002523 ... P06702 11851337
    13845 1irj:D (2.1) BS01 CA ? GO:0002523 ... P06702 11851337
    13846 1irj:D (2.1) BS02 CA ? GO:0002523 ... P06702 11851337
    13847 1irj:D (2.1) BS03 CPS ? GO:0002523 ... P06702 11851337
    13848 1irj:E (2.1) BS01 CPS ? GO:0002523 ... P06702 11851337
    13849 1irj:E (2.1) BS02 CA ? GO:0002523 ... P06702 11851337
    13850 1irj:E (2.1) BS03 CA ? GO:0002523 ... P06702 11851337
    13851 1irj:F (2.1) BS01 CA ? GO:0002523 ... P06702 11851337
    13852 1irj:F (2.1) BS02 CA ? GO:0002523 ... P06702 11851337
    13853 1irj:G (2.1) BS01 CA ? GO:0002523 ... P06702 11851337
    13854 1irj:G (2.1) BS02 CA ? GO:0002523 ... P06702 11851337
    13855 1irj:G (2.1) BS03 CPS ? GO:0002523 ... P06702 11851337
    13856 1irj:H (2.1) BS01 CA ? GO:0002523 ... P06702 11851337
    13857 1irj:H (2.1) BS02 CA ? GO:0002523 ... P06702 11851337
    13858 1iru:1 (2.75) BS01 MG ? GO:0005839 ... Q2TBX6 12015144
    13859 1iru:1 (2.75) BS02 MG ? GO:0005839 ... Q2TBX6 12015144
    13860 1iru:A (2.75) BS01 MG ? GO:0000502 ... Q2YDE4 12015144
    13861 1iru:B (2.75) BS01 MG ? GO:0000502 ... Q3T0Y5 12015144
    13862 1iru:C (2.75) BS01 MG ? GO:0000502 ... Q3ZCK9 12015144
    13863 1iru:D (2.75) BS01 MG ? GO:0000502 ... Q3ZBG0 12015144
    13864 1iru:G (2.75) BS01 MG ? GO:0000502 ... Q58DU5 12015144
    13865 1iru:G (2.75) BS02 MG ? GO:0000502 ... Q58DU5 12015144
    13866 1iru:I (2.75) BS01 MG 3.4.25.1 GO:0004298 ... Q2TBP0 12015144
    13867 1iru:J (2.75) BS01 MG ? GO:0000502 ... P33672 12015144
    13868 1iru:J (2.75) BS02 MG ? GO:0000502 ... P33672 12015144
    13869 1iru:K (2.75) BS01 MG ? GO:0000502 ... Q5E9K0 12015144
    13870 1iru:L (2.75) BS01 MG 3.4.25.1 GO:0004298 ... Q32KL2 12015144
    13871 1iru:M (2.75) BS01 MG ? GO:0005839 ... Q2TBX6 12015144
    13872 1iru:M (2.75) BS02 MG ? GO:0005839 ... Q2TBX6 12015144
    13873 1iru:O (2.75) BS01 MG ? GO:0000502 ... Q2YDE4 12015144
    13874 1iru:P (2.75) BS01 MG ? GO:0000502 ... Q3T0Y5 12015144
    13875 1iru:Q (2.75) BS01 MG ? GO:0000502 ... Q3ZCK9 12015144
    13876 1iru:R (2.75) BS01 MG ? GO:0000502 ... Q3ZBG0 12015144
    13877 1iru:U (2.75) BS01 MG ? GO:0000502 ... Q58DU5 12015144
    13878 1iru:U (2.75) BS02 MG ? GO:0000502 ... Q58DU5 12015144
    13879 1iru:W (2.75) BS01 MG 3.4.25.1 GO:0004298 ... Q2TBP0 12015144
    13880 1iru:X (2.75) BS01 MG ? GO:0000502 ... P33672 12015144
    13881 1iru:X (2.75) BS02 MG ? GO:0000502 ... P33672 12015144
    13882 1iru:Y (2.75) BS01 MG ? GO:0000502 ... Q5E9K0 12015144
    13883 1iru:Z (2.75) BS01 MG 3.4.25.1 GO:0004298 ... Q32KL2 12015144
    13884 1irv:A (1.9) BS01 HEM ? GO:0005515 ... P00044 8718869
    13885 1irw:A (2.0) BS01 HEM ? GO:0005515 ... P00044 8718869
    13886 1irx:A (2.6) BS01 ZN 6.1.1.6 GO:0000049 ... O57963 11887185
    13887 1irx:A (2.6) BS02 ZN 6.1.1.6 GO:0000049 ... O57963 11887185
    13888 1irx:B (2.6) BS01 ZN 6.1.1.6 GO:0000049 ... O57963 11887185
    13889 1is2:A (2.2) BS01 FAD 1.3.3.6 GO:0000038 ... P07872 11872165
    13890 1is2:A (2.2) BS02 FAD 1.3.3.6 GO:0000038 ... P07872 11872165
    13891 1is2:B (2.2) BS01 FAD 1.3.3.6 GO:0000038 ... P07872 11872165
    13892 1is2:B (2.2) BS02 FAD 1.3.3.6 GO:0000038 ... P07872 11872165
    13893 1is3:A (1.45) BS01 BGC ? GO:0005615 ... Q9YIC2 12206768
    13894 1is3:A (1.45) BS02 GAL ? GO:0005615 ... Q9YIC2 12206768
    13895 1is4:A (1.9) BS01 BGC ? GO:0005615 ... Q9YIC2 12206768
    13896 1is4:A (1.9) BS02 GAL ? GO:0005615 ... Q9YIC2 12206768
    13897 1is7:K (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    13898 1is7:K (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    13899 1is7:L (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    13900 1is7:L (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    13901 1is7:M (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    13902 1is7:M (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    13903 1is7:N (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    13904 1is7:N (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    13905 1is7:O (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    13906 1is7:O (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    13907 1is7:P (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    13908 1is7:P (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    13909 1is7:Q (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    13910 1is7:Q (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    13911 1is7:R (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    13912 1is7:R (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    13913 1is7:S (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    13914 1is7:S (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    13915 1is7:T (2.8) BS01 PHE ? GO:0004857 ... P70552 11818540
    13916 1is7:T (2.8) BS02 PHE ? GO:0004857 ... P70552 11818540
    13917 1is8:A (2.7) BS01 ZN 3.5.4.16 GO:0003924 ... P22288 11818540
    13918 1is8:B (2.7) BS01 ZN 3.5.4.16 GO:0003924 ... P22288 11818540
    13919 1is8:C (2.7) BS01 ZN 3.5.4.16 GO:0003924 ... P22288 11818540
    13920 1is8:D (2.7) BS01 ZN 3.5.4.16 GO:0003924 ... P22288 11818540
    13921 1is8:E (2.7) BS01 ZN 3.5.4.16 GO:0003924 ... P22288 11818540
    13922 1is8:F (2.7) BS01 ZN 3.5.4.16 GO:0003924 ... P22288 11818540
    13923 1is8:G (2.7) BS01 ZN 3.5.4.16 GO:0003924 ... P22288 11818540
    13924 1is8:H (2.7) BS01 ZN 3.5.4.16 GO:0003924 ... P22288 11818540
    13925 1is8:I (2.7) BS01 ZN 3.5.4.16 GO:0003924 ... P22288 11818540
    13926 1is8:J (2.7) BS01 ZN 3.5.4.16 GO:0003924 ... P22288 11818540
    13927 1is8:K (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    13928 1is8:K (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    13929 1is8:L (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    13930 1is8:L (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    13931 1is8:M (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    13932 1is8:M (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    13933 1is8:N (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    13934 1is8:N (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    13935 1is8:O (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    13936 1is8:O (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    13937 1is8:P (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    13938 1is8:P (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    13939 1is8:Q (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    13940 1is8:Q (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    13941 1is8:R (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    13942 1is8:R (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    13943 1is8:S (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    13944 1is8:S (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    13945 1is8:T (2.7) BS01 PHE ? GO:0004857 ... P70552 11818540
    13946 1is8:T (2.7) BS02 PHE ? GO:0004857 ... P70552 11818540
    13947 1isa:A (1.8) BS01 FE2 1.15.1.1 GO:0000303 ... P0AGD3 7849024
    13948 1isa:B (1.8) BS01 FE2 1.15.1.1 GO:0000303 ... P0AGD3 7849024
    13949 1isb:A (1.85) BS01 FE 1.15.1.1 GO:0000303 ... P0AGD3 7849024
    13950 1isb:B (1.85) BS01 FE 1.15.1.1 GO:0000303 ... P0AGD3 7849024
    13951 1isc:A (1.8) BS01 FE 1.15.1.1 GO:0000303 ... P0AGD3 7849024
    13952 1isc:A (1.8) BS02 AZI 1.15.1.1 GO:0000303 ... P0AGD3 7849024
    13953 1isc:B (1.8) BS01 FE 1.15.1.1 GO:0000303 ... P0AGD3 7849024
    13954 1isc:B (1.8) BS02 AZI 1.15.1.1 GO:0000303 ... P0AGD3 7849024
    13955 1isg:A (2.6) BS01 AGS 3.2.2.6 GO:0001931 ... Q10588 11866528
    13956 1isg:B (2.6) BS01 AGS 3.2.2.6 GO:0001931 ... Q10588 11866528
    13957 1ish:A (2.4) BS01 ENP 3.2.2.6 GO:0001931 ... Q10588 11866528
    13958 1ish:B (2.4) BS01 ENP 3.2.2.6 GO:0001931 ... Q10588 11866528
    13959 1isi:A (2.1) BS01 NCA 3.2.2.6 GO:0001931 ... Q10588 11866528
    13960 1isi:A (2.1) BS02 ENQ 3.2.2.6 GO:0001931 ... Q10588 11866528
    13961 1isi:B (2.1) BS01 NCA 3.2.2.6 GO:0001931 ... Q10588 11866528
    13962 1isi:B (2.1) BS02 ENQ 3.2.2.6 GO:0001931 ... Q10588 11866528
    13963 1isj:A (2.3) BS01 NMN 3.2.2.6 GO:0001931 ... Q10588 11866528
    13964 1isj:B (2.3) BS01 NMN 3.2.2.6 GO:0001931 ... Q10588 11866528
    13965 1ism:A (3.0) BS01 NCA 3.2.2.6 GO:0001931 ... Q10588 11866528
    13966 1ism:B (3.0) BS01 NCA 3.2.2.6 GO:0001931 ... Q10588 11866528
    13967 1iso:A (1.9) BS01 NAD 1.1.1.42 GO:0000287 ... P08200 8639526
    13968 1isp:A (1.3) BS01 GOL 3.1.1.3 GO:0004806 ... P37957 12077437
    13969 1isr:A (4.0) BS01 GLU ? GO:0004930 ... P23385 11867751
    13970 1iss:A (3.3) BS01 MCG ? GO:0004930 ... P23385 11867751 BindingDB: Ki=>10000nM
    13971 1iss:B (3.3) BS01 MCG ? GO:0004930 ... P23385 11867751 BindingDB: Ki=>10000nM
    13972 1it1:A (-1.00) BS01 HEC ? GO:0009055 ... P00132 12054869
    13973 1it1:A (-1.00) BS02 HEC ? GO:0009055 ... P00132 12054869
    13974 1it1:A (-1.00) BS03 HEC ? GO:0009055 ... P00132 12054869
    13975 1it1:A (-1.00) BS04 HEC ? GO:0009055 ... P00132 12054869
    13976 1it6:A (2.0) BS01 MN 3.1.3.16 GO:0000070 ... P36873 12015153
    13977 1it6:A (2.0) BS02 MN 3.1.3.16 GO:0000070 ... P36873 12015153
    13978 1it6:A (2.0) BS03 CYU 3.1.3.16 GO:0000070 ... P36873 12015153 MOAD: Ki=4.1nM
    PDBbind: -logKd/Ki=8.39, Ki=4.1nM
    13979 1it6:B (2.0) BS01 MN 3.1.3.16 GO:0000070 ... P36873 12015153
    13980 1it6:B (2.0) BS02 MN 3.1.3.16 GO:0000070 ... P36873 12015153
    13981 1it6:B (2.0) BS03 CYU 3.1.3.16 GO:0000070 ... P36873 12015153 MOAD: Ki=4.1nM
    13982 1it7:A (2.3) BS01 ZN 2.4.2.48 GO:0002099 ... O58843 12054814
    13983 1it7:A (2.3) BS02 MG 2.4.2.48 GO:0002099 ... O58843 12054814
    13984 1it7:A (2.3) BS03 GUN 2.4.2.48 GO:0002099 ... O58843 12054814
    13985 1it7:B (2.3) BS01 ZN 2.4.2.48 GO:0002099 ... O58843 12054814
    13986 1it7:B (2.3) BS02 MG 2.4.2.48 GO:0002099 ... O58843 12054814
    13987 1it8:A (2.5) BS01 ZN 2.4.2.48 GO:0002099 ... O58843 12054814
    13988 1it8:A (2.5) BS02 MG 2.4.2.48 GO:0002099 ... O58843 12054814
    13989 1it8:A (2.5) BS03 PQ0 2.4.2.48 GO:0002099 ... O58843 12054814
    13990 1it8:B (2.5) BS01 ZN 2.4.2.48 GO:0002099 ... O58843 12054814
    13991 1it8:B (2.5) BS02 MG 2.4.2.48 GO:0002099 ... O58843 12054814
    13992 1itk:A (2.0) BS01 HEM 1.11.1.21 GO:0004096 ... O59651 12172540
    13993 1itk:B (2.0) BS01 HEM 1.11.1.21 GO:0004096 ... O59651 12172540
    13994 1itq:A (2.3) BS01 ZN 3.4.13.19
    3.5.2.6
    GO:0005515 ... P16444 12144777
    13995 1itq:A (2.3) BS02 ZN 3.4.13.19
    3.5.2.6
    GO:0005515 ... P16444 12144777
    13996 1itq:B (2.3) BS01 ZN 3.4.13.19
    3.5.2.6
    GO:0005515 ... P16444 12144777
    13997 1itq:B (2.3) BS02 ZN 3.4.13.19
    3.5.2.6
    GO:0005515 ... P16444 12144777
    13998 1itu:A (2.0) BS01 ZN 3.4.13.19
    3.5.2.6
    GO:0005515 ... P16444 12144777
    13999 1itu:A (2.0) BS02 ZN 3.4.13.19
    3.5.2.6
    GO:0005515 ... P16444 12144777
    14000 1itu:A (2.0) BS03 CIL 3.4.13.19
    3.5.2.6
    GO:0005515 ... P16444 12144777

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218