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BioLiP
Download all results in tab-seperated text for 594392 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    12201 1hqg:B (2.0) BS03 ORN 3.5.3.1 GO:0000050 ... P07824 11258880
    12202 1hqg:B (2.0) BS04 URE 3.5.3.1 GO:0000050 ... P07824 11258880
    12203 1hqg:C (2.0) BS01 MN 3.5.3.1 GO:0000050 ... P07824 11258880
    12204 1hqg:C (2.0) BS02 MN 3.5.3.1 GO:0000050 ... P07824 11258880
    12205 1hqg:C (2.0) BS03 ORN 3.5.3.1 GO:0000050 ... P07824 11258880
    12206 1hqg:C (2.0) BS04 URE 3.5.3.1 GO:0000050 ... P07824 11258880
    12207 1hqh:A (2.8) BS01 MN 3.5.3.1 GO:0000050 ... P07824 11258880
    12208 1hqh:A (2.8) BS02 MN 3.5.3.1 GO:0000050 ... P07824 11258880
    12209 1hqh:A (2.8) BS03 NNH 3.5.3.1 GO:0000050 ... P07824 11258880 PDBbind: -logKd/Ki=6.30, Ki=0.5uM
    BindingDB: IC50=2000nM
    12210 1hqh:B (2.8) BS01 MN 3.5.3.1 GO:0000050 ... P07824 11258880
    12211 1hqh:B (2.8) BS02 MN 3.5.3.1 GO:0000050 ... P07824 11258880
    12212 1hqh:B (2.8) BS03 NNH 3.5.3.1 GO:0000050 ... P07824 11258880 BindingDB: IC50=2000nM
    12213 1hqh:C (2.8) BS01 MN 3.5.3.1 GO:0000050 ... P07824 11258880
    12214 1hqh:C (2.8) BS02 MN 3.5.3.1 GO:0000050 ... P07824 11258880
    12215 1hqh:C (2.8) BS03 NNH 3.5.3.1 GO:0000050 ... P07824 11258880 BindingDB: IC50=2000nM
    12216 1hqp:A (2.3) BS01 PRZ ? GO:0005549 ... P81245 11119644
    12217 1hqr:A (3.2) BS01 peptide ? GO:0006955 ... P01903 11163233
    12218 1hqr:B (3.2) BS01 peptide ? GO:0006955 ... Q30154 11163233
    12219 1hqr:D (3.2) BS01 peptide ? GO:0005576 ... Q8NKX2 11163233
    12220 1hqr:D (3.2) BS02 ZN ? GO:0005576 ... Q8NKX2 11163233
    12221 1hqt:A (2.2) BS01 NAP 1.1.1.19
    1.1.1.2
    1.1.1.20
    1.1.1.372
    1.1.1.54
    1.6.-.-
    GO:0004032 ... P50578 11306083
    12222 1hqv:A (2.3) BS01 CA ? GO:0000287 ... P12815 11525164
    12223 1hqv:A (2.3) BS02 CA ? GO:0000287 ... P12815 11525164
    12224 1hqv:A (2.3) BS03 CA ? GO:0000287 ... P12815 11525164
    12225 1hqx:A (3.0) BS01 MN 3.5.3.1 GO:0000050 ... P07824 11278703
    12226 1hqx:A (3.0) BS02 MN 3.5.3.1 GO:0000050 ... P07824 11278703
    12227 1hqx:B (3.0) BS01 MN 3.5.3.1 GO:0000050 ... P07824 11278703
    12228 1hqx:B (3.0) BS02 MN 3.5.3.1 GO:0000050 ... P07824 11278703
    12229 1hqx:C (3.0) BS01 MN 3.5.3.1 GO:0000050 ... P07824 11278703
    12230 1hqx:C (3.0) BS02 MN 3.5.3.1 GO:0000050 ... P07824 11278703
    12231 1hqy:E (2.8) BS01 ADP ? GO:0000287 ... P0A6H5 11709174
    12232 1hqy:F (2.8) BS01 ADP ? GO:0000287 ... P0A6H5 11709174
    12233 1hr0:B (3.2) BS01 rna ? GO:0003735 ... P80371 11228145
    12234 1hr0:C (3.2) BS01 rna ? GO:0003676 ... P80372 11228145
    12235 1hr0:D (3.2) BS01 rna ? GO:0003723 ... P80373 11228145
    12236 1hr0:E (3.2) BS01 rna ? GO:0003723 ... Q5SHQ5 11228145
    12237 1hr0:F (3.2) BS01 rna ? GO:0003735 ... Q5SLP8 11228145
    12238 1hr0:G (3.2) BS01 rna ? GO:0000028 ... P17291 11228145
    12239 1hr0:H (3.2) BS01 rna ? GO:0003735 ... P0DOY9 11228145
    12240 1hr0:I (3.2) BS01 rna ? GO:0000049 ... P80374 11228145
    12241 1hr0:J (3.2) BS01 rna ? GO:0000049 ... Q5SHN7 11228145
    12242 1hr0:K (3.2) BS01 rna ? GO:0003735 ... P80376 11228145
    12243 1hr0:L (3.2) BS01 rna ? GO:0000049 ... Q5SHN3 11228145
    12244 1hr0:M (3.2) BS01 rna ? GO:0000049 ... P80377 11228145
    12245 1hr0:N (3.2) BS01 rna ? GO:0003735 ... P0DOY6 11228145
    12246 1hr0:N (3.2) BS02 ZN ? GO:0003735 ... P0DOY6 11228145
    12247 1hr0:O (3.2) BS01 rna ? GO:0003735 ... Q5SJ76 11228145
    12248 1hr0:P (3.2) BS01 rna ? GO:0003735 ... Q5SJH3 11228145
    12249 1hr0:Q (3.2) BS01 rna ? GO:0003735 ... P0DOY7 11228145
    12250 1hr0:R (3.2) BS01 rna ? GO:0003735 ... Q5SLQ0 11228145
    12251 1hr0:S (3.2) BS01 rna ? GO:0000028 ... Q5SHP2 11228145
    12252 1hr0:T (3.2) BS01 rna ? GO:0003723 ... P80380 11228145
    12253 1hr0:W (3.2) BS01 rna ? GO:0003723 ... Q5SHR1 11228145
    12254 1hr6:B (2.5) BS01 ZN 3.4.24.64 GO:0004222 ... P10507 11470436
    12255 1hr6:D (2.5) BS01 ZN 3.4.24.64 GO:0004222 ... P10507 11470436
    12256 1hr6:F (2.5) BS01 ZN 3.4.24.64 GO:0004222 ... P10507 11470436
    12257 1hr6:H (2.5) BS01 ZN 3.4.24.64 GO:0004222 ... P10507 11470436
    12258 1hr7:B (2.55) BS01 ZN 3.4.24.64 GO:0004222 ... P10507 11470436
    12259 1hr7:D (2.55) BS01 ZN 3.4.24.64 GO:0004222 ... P10507 11470436
    12260 1hr7:F (2.55) BS01 ZN 3.4.24.64 GO:0004222 ... P10507 11470436
    12261 1hr7:H (2.55) BS01 ZN 3.4.24.64 GO:0004222 ... P10507 11470436
    12262 1hr8:B (2.7) BS01 peptide 3.4.24.64 GO:0004222 ... P10507 11470436
    12263 1hr8:B (2.7) BS02 ZN 3.4.24.64 GO:0004222 ... P10507 11470436
    12264 1hr8:D (2.7) BS01 peptide 3.4.24.64 GO:0004222 ... P10507 11470436
    12265 1hr8:D (2.7) BS02 ZN 3.4.24.64 GO:0004222 ... P10507 11470436
    12266 1hr8:F (2.7) BS01 peptide 3.4.24.64 GO:0004222 ... P10507 11470436
    12267 1hr8:F (2.7) BS02 ZN 3.4.24.64 GO:0004222 ... P10507 11470436
    12268 1hr8:H (2.7) BS01 peptide 3.4.24.64 GO:0004222 ... P10507 11470436
    12269 1hr8:H (2.7) BS02 ZN 3.4.24.64 GO:0004222 ... P10507 11470436
    12270 1hr9:B (3.01) BS01 peptide 3.4.24.64 GO:0004222 ... P10507 11470436
    12271 1hr9:B (3.01) BS02 ZN 3.4.24.64 GO:0004222 ... P10507 11470436
    12272 1hr9:D (3.01) BS01 peptide 3.4.24.64 GO:0004222 ... P10507 11470436
    12273 1hr9:D (3.01) BS02 ZN 3.4.24.64 GO:0004222 ... P10507 11470436
    12274 1hr9:F (3.01) BS01 peptide 3.4.24.64 GO:0004222 ... P10507 11470436
    12275 1hr9:F (3.01) BS02 ZN 3.4.24.64 GO:0004222 ... P10507 11470436
    12276 1hr9:H (3.01) BS01 peptide 3.4.24.64 GO:0004222 ... P10507 11470436
    12277 1hr9:H (3.01) BS02 ZN 3.4.24.64 GO:0004222 ... P10507 11470436
    12278 1hrc:A (1.9) BS01 HEC ? GO:0005515 ... P00004 2166170
    12279 1hrm:A (1.7) BS01 HEM 1.11.1.-
    1.7.-.-
    GO:0004601 ... P68082 7849057
    12280 1hrq:A (-1.00) BS01 SF4 ? GO:0009055 ... P00260 7819198
    12281 1hrr:A (-1.00) BS01 SF4 ? GO:0009055 ... P00260 7819198
    12282 1hrs:A (2.6) BS01 PP9 ? GO:0005506 ... P02791 15299370
    12283 1hs6:A (1.95) BS01 ZN 3.3.2.6
    3.4.11.4
    GO:0003723 ... P09960 11175901
    12284 1hs6:A (1.95) BS02 BES 3.3.2.6
    3.4.11.4
    GO:0003723 ... P09960 11175901 PDBbind: -logKd/Ki=5.38, IC50=4.2uM
    BindingDB: IC50=4000nM, Kd=2050nM, Ki=320nM
    12285 1hse:A (2.2) BS01 FE 3.4.21.- GO:0005576 ... P02788 9003186
    12286 1hse:A (2.2) BS02 CO3 3.4.21.- GO:0005576 ... P02788 9003186
    12287 1hsj:A (2.3) BS01 GLC ? GO:0003677 ... P0AEX9
    Q9F0R1
    11381122
    12288 1hsj:A (2.3) BS02 GLC ? GO:0003677 ... P0AEX9
    Q9F0R1
    11381122
    12289 1hsj:B (2.3) BS01 GLC ? GO:0003677 ... P0AEX9
    Q9F0R1
    11381122
    12290 1hsj:B (2.3) BS02 GLC ? GO:0003677 ... P0AEX9
    Q9F0R1
    11381122
    12291 1hsk:A (2.3) BS01 FAD 1.3.1.98 GO:0005737 ... P61431 11327854
    12292 1hsl:A (1.89) BS01 HIS ? GO:0006865 ... P0AEU0 8161536 MOAD: Kd=0.064uM
    PDBbind: -logKd/Ki=7.19, Kd=0.064uM
    12293 1hsl:B (1.89) BS01 HIS ? GO:0006865 ... P0AEU0 8161536 MOAD: Kd=0.064uM
    12294 1hso:A (2.5) BS01 ZN 1.1.1.1 GO:0004022 ... P07327 11274460
    12295 1hso:A (2.5) BS02 ZN 1.1.1.1 GO:0004022 ... P07327 11274460
    12296 1hso:A (2.5) BS03 NAD 1.1.1.1 GO:0004022 ... P07327 11274460
    12297 1hso:A (2.5) BS04 PYZ 1.1.1.1 GO:0004022 ... P07327 11274460
    12298 1hso:B (2.5) BS01 ZN 1.1.1.1 GO:0004022 ... P07327 11274460
    12299 1hso:B (2.5) BS02 ZN 1.1.1.1 GO:0004022 ... P07327 11274460
    12300 1hso:B (2.5) BS03 NAD 1.1.1.1 GO:0004022 ... P07327 11274460
    12301 1hso:B (2.5) BS04 PYZ 1.1.1.1 GO:0004022 ... P07327 11274460
    12302 1hsr:A (1.6) BS01 CA 1.11.1.7 GO:0000302 ... P28313 9257700
    12303 1hsr:A (1.6) BS02 CA 1.11.1.7 GO:0000302 ... P28313 9257700
    12304 1hsr:A (1.6) BS03 HEM 1.11.1.7 GO:0000302 ... P28313 9257700
    12305 1hsr:A (1.6) BS04 BHO 1.11.1.7 GO:0000302 ... P28313 9257700
    12306 1hsy:A (1.9) BS01 HEM 1.11.1.-
    1.7.-.-
    GO:0004601 ... P68082 7654702
    12307 1hsz:A (2.2) BS01 ZN 1.1.1.105 GO:0001523 ... P00325 11274460
    12308 1hsz:A (2.2) BS02 ZN 1.1.1.105 GO:0001523 ... P00325 11274460
    12309 1hsz:A (2.2) BS03 NAD 1.1.1.105 GO:0001523 ... P00325 11274460
    12310 1hsz:B (2.2) BS01 ZN 1.1.1.105 GO:0001523 ... P00325 11274460
    12311 1hsz:B (2.2) BS02 ZN 1.1.1.105 GO:0001523 ... P00325 11274460
    12312 1hsz:B (2.2) BS03 NAD 1.1.1.105 GO:0001523 ... P00325 11274460
    12313 1ht0:A (2.0) BS01 ZN 1.1.1.1 GO:0004022 ... P00326 11274460
    12314 1ht0:A (2.0) BS02 ZN 1.1.1.1 GO:0004022 ... P00326 11274460
    12315 1ht0:A (2.0) BS03 NAD 1.1.1.1 GO:0004022 ... P00326 11274460
    12316 1ht0:B (2.0) BS01 ZN 1.1.1.1 GO:0004022 ... P00326 11274460
    12317 1ht0:B (2.0) BS02 ZN 1.1.1.1 GO:0004022 ... P00326 11274460
    12318 1ht0:B (2.0) BS03 NAD 1.1.1.1 GO:0004022 ... P00326 11274460
    12319 1ht1:E (2.8) BS01 ADP ? GO:0000287 ... P0A6H5 11709174
    12320 1ht1:F (2.8) BS01 ADP ? GO:0000287 ... P0A6H5 11709174
    12321 1ht1:G (2.8) BS01 ADP ? GO:0000287 ... P0A6H5 11709174
    12322 1ht1:I (2.8) BS01 ADP ? GO:0000287 ... P0A6H5 11709174
    12323 1ht2:E (2.8) BS01 ADP ? GO:0000287 ... P0A6H5 11709174
    12324 1ht2:F (2.8) BS01 ADP ? GO:0000287 ... P0A6H5 11709174
    12325 1ht2:G (2.8) BS01 ADP ? GO:0000287 ... P0A6H5 11709174
    12326 1ht2:H (2.8) BS01 ADP ? GO:0000287 ... P0A6H5 11709174
    12327 1ht5:A (2.75) BS01 HEM 1.14.99.1 GO:0001516 ... P05979 11318639
    12328 1ht5:A (2.75) BS02 FL2 1.14.99.1 GO:0001516 ... P05979 11318639 BindingDB: IC50=210000nM
    12329 1ht5:B (2.75) BS01 HEM 1.14.99.1 GO:0001516 ... P05979 11318639
    12330 1ht5:B (2.75) BS02 FL2 1.14.99.1 GO:0001516 ... P05979 11318639 BindingDB: IC50=210000nM
    12331 1ht6:A (1.5) BS01 CA 3.2.1.1 GO:0004556 ... P00693 12906828
    12332 1ht6:A (1.5) BS02 CA 3.2.1.1 GO:0004556 ... P00693 12906828
    12333 1ht6:A (1.5) BS03 CA 3.2.1.1 GO:0004556 ... P00693 12906828
    12334 1ht8:A (2.69) BS01 HEM 1.14.99.1 GO:0001516 ... P05979 11318639
    12335 1ht8:A (2.69) BS02 34C 1.14.99.1 GO:0001516 ... P05979 11318639
    12336 1ht8:B (2.69) BS01 HEM 1.14.99.1 GO:0001516 ... P05979 11318639
    12337 1ht8:B (2.69) BS02 34C 1.14.99.1 GO:0001516 ... P05979 11318639
    12338 1ht9:A (1.76) BS01 CA ? GO:0005499 ... P02633 11316872
    12339 1ht9:A (1.76) BS02 CA ? GO:0005499 ... P02633 11316872
    12340 1ht9:B (1.76) BS01 CA ? GO:0005499 ... P02633 11316872
    12341 1ht9:B (1.76) BS02 CA ? GO:0005499 ... P02633 11316872
    12342 1htb:A (2.4) BS01 ZN 1.1.1.105 GO:0001523 ... P00325 8663387
    12343 1htb:A (2.4) BS02 ZN 1.1.1.105 GO:0001523 ... P00325 8663387
    12344 1htb:A (2.4) BS03 NAD 1.1.1.105 GO:0001523 ... P00325 8663387
    12345 1htb:A (2.4) BS04 PYZ 1.1.1.105 GO:0001523 ... P00325 8663387
    12346 1htb:B (2.4) BS01 ZN 1.1.1.105 GO:0001523 ... P00325 8663387
    12347 1htb:B (2.4) BS02 ZN 1.1.1.105 GO:0001523 ... P00325 8663387
    12348 1htb:B (2.4) BS03 NAD 1.1.1.105 GO:0001523 ... P00325 8663387 MOAD: Kd=670uM
    12349 1htb:B (2.4) BS04 PYZ 1.1.1.105 GO:0001523 ... P00325 8663387
    12350 1hti:B (2.8) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P60174 8061610 PDBbind: -logKd/Ki=5.13, Ki=7.4uM
    12351 1htm:B (2.5) BS01 peptide ? GO:0019031 ... P03437 8072525
    12352 1htm:D (2.5) BS01 peptide ? GO:0019031 ... P03437 8072525
    12353 1htm:F (2.5) BS01 peptide ? GO:0019031 ... P03437 8072525
    12354 1htn:A (2.8) BS01 CA ? GO:0001503 ... P05452 9256258
    12355 1htn:A (2.8) BS02 CA ? GO:0001503 ... P05452 9256258
    12356 1hto:A (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12357 1hto:A (2.4) BS02 AMP 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12358 1hto:B (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12359 1hto:B (2.4) BS02 AMP 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12360 1hto:C (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12361 1hto:C (2.4) BS02 AMP 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12362 1hto:D (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12363 1hto:D (2.4) BS02 AMP 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12364 1hto:E (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12365 1hto:E (2.4) BS02 AMP 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12366 1hto:F (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12367 1hto:F (2.4) BS02 AMP 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12368 1hto:G (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12369 1hto:G (2.4) BS02 AMP 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12370 1hto:H (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12371 1hto:H (2.4) BS02 AMP 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12372 1hto:I (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12373 1hto:I (2.4) BS02 AMP 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12374 1hto:J (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12375 1hto:J (2.4) BS02 AMP 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12376 1hto:K (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12377 1hto:K (2.4) BS02 AMP 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12378 1hto:L (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12379 1hto:L (2.4) BS02 AMP 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12380 1hto:M (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12381 1hto:M (2.4) BS02 AMP 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12382 1hto:N (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12383 1hto:N (2.4) BS02 AMP 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12384 1hto:O (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12385 1hto:O (2.4) BS02 AMP 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12386 1hto:P (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12387 1hto:P (2.4) BS02 AMP 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12388 1hto:Q (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12389 1hto:Q (2.4) BS02 AMP 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12390 1hto:R (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12391 1hto:R (2.4) BS02 AMP 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12392 1hto:S (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12393 1hto:S (2.4) BS02 AMP 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12394 1hto:T (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12395 1hto:T (2.4) BS02 AMP 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12396 1hto:U (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12397 1hto:U (2.4) BS02 AMP 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12398 1hto:V (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12399 1hto:V (2.4) BS02 AMP 6.3.1.2 GO:0000287 ... P9WN39 12146952
    12400 1hto:W (2.4) BS01 MN 6.3.1.2 GO:0000287 ... P9WN39 12146952

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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