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BioLiP
Download all results in tab-seperated text for 594392 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    12001 1hmw:A (2.3) BS01 MAN 4.2.2.5 GO:0003824 ... Q59288 11327856
    12002 1hmw:A (2.3) BS02 GCU 4.2.2.5 GO:0003824 ... Q59288 11327856
    12003 1hmw:A (2.3) BS03 NG6 4.2.2.5 GO:0003824 ... Q59288 11327856
    12004 1hmw:A (2.3) BS04 BDP 4.2.2.5 GO:0003824 ... Q59288 11327856
    12005 1hmw:A (2.3) BS05 ASG 4.2.2.5 GO:0003824 ... Q59288 11327856
    12006 1hmw:A (2.3) BS06 CA 4.2.2.5 GO:0003824 ... Q59288 11327856
    12007 1hn1:A (3.0) BS01 MG 3.2.1.23 GO:0000287 ... P00722 11518535
    12008 1hn1:A (3.0) BS02 MG 3.2.1.23 GO:0000287 ... P00722 11518535
    12009 1hn1:B (3.0) BS01 MG 3.2.1.23 GO:0000287 ... P00722 11518535
    12010 1hn1:B (3.0) BS02 MG 3.2.1.23 GO:0000287 ... P00722 11518535
    12011 1hn1:C (3.0) BS01 MG 3.2.1.23 GO:0000287 ... P00722 11518535
    12012 1hn1:C (3.0) BS02 MG 3.2.1.23 GO:0000287 ... P00722 11518535
    12013 1hn1:D (3.0) BS01 MG 3.2.1.23 GO:0000287 ... P00722 11518535
    12014 1hn1:D (3.0) BS02 MG 3.2.1.23 GO:0000287 ... P00722 11518535
    12015 1hn2:A (1.8) BS01 ANC ? GO:0005549 ... P07435 11114310 MOAD: Kd=1uM
    PDBbind: -logKd/Ki=6.00, Kd=1.0uM
    12016 1hn2:B (1.8) BS01 ANC ? GO:0005549 ... P07435 11114310 MOAD: Kd=1uM
    PDBbind: -logKd/Ki=6.00, Kd=1.0uM
    12017 1hn2:B (1.8) BS02 3OL ? GO:0005549 ... P07435 11114310 MOAD: Kd=3.3uM
    12018 1hn4:A (1.5) BS01 CA 3.1.1.4 GO:0002446 ... P00592 11560489
    12019 1hn4:A (1.5) BS02 SO4 3.1.1.4 GO:0002446 ... P00592 11560489
    12020 1hn4:A (1.5) BS03 SO4 3.1.1.4 GO:0002446 ... P00592 11560489
    12021 1hn4:A (1.5) BS04 MJI 3.1.1.4 GO:0002446 ... P00592 11560489 MOAD: Kd=0.15mM
    PDBbind: -logKd/Ki=3.82, Kd=0.15mM
    12022 1hn4:B (1.5) BS01 CA 3.1.1.4 GO:0002446 ... P00592 11560489
    12023 1hn4:B (1.5) BS02 SO4 3.1.1.4 GO:0002446 ... P00592 11560489
    12024 1hna:A (1.85) BS01 GDN 2.5.1.18 GO:0004364 ... P28161 8182750
    12025 1hnb:A (3.5) BS01 GDN 2.5.1.18 GO:0004364 ... P28161 8182750
    12026 1hnb:B (3.5) BS01 GDN 2.5.1.18 GO:0004364 ... P28161 8182750
    12027 1hnc:A (3.0) BS01 GDN 2.5.1.18 GO:0004364 ... P28161 8182750
    12028 1hnc:B (3.0) BS01 GDN 2.5.1.18 GO:0004364 ... P28161 8182750
    12029 1hnc:C (3.0) BS01 GDN 2.5.1.18 GO:0004364 ... P28161 8182750
    12030 1hnc:D (3.0) BS01 GDN 2.5.1.18 GO:0004364 ... P28161 8182750
    12031 1hnd:A (1.6) BS01 COA 2.3.1.180 GO:0004315 ... P0A6R0 11243824
    12032 1hne:E (1.84) BS01 peptide 3.4.21.37 GO:0000122 ... P08246 2911584
    12033 1hnh:A (1.9) BS01 COA 2.3.1.180 GO:0004315 ... P0A6R0 11243824
    12034 1hnj:A (1.46) BS01 MLC 2.3.1.180 GO:0004315 ... P0A6R0 11243824
    12035 1hnl:A (1.8) BS01 GSH 3.2.1.17 GO:0003796 ... P61626 15299791
    12036 1hnn:A (2.4) BS01 SAH 2.1.1.28 GO:0004603 ... P11086 11591352
    12037 1hnn:A (2.4) BS02 SKF 2.1.1.28 GO:0004603 ... P11086 11591352 MOAD: Ki=0.58uM
    PDBbind: -logKd/Ki=6.24, Ki=0.58uM
    BindingDB: Ki=280nM
    12038 1hnn:B (2.4) BS01 SAH 2.1.1.28 GO:0004603 ... P11086 11591352
    12039 1hnn:B (2.4) BS02 SKF 2.1.1.28 GO:0004603 ... P11086 11591352 MOAD: Ki=0.58uM
    BindingDB: Ki=280nM
    12040 1hnu:A (2.15) BS01 REO 5.3.3.8 GO:0004165 ... Q05871 11399063
    12041 1hnu:A (2.15) BS02 REO 5.3.3.8 GO:0004165 ... Q05871 11399063
    12042 1hnw:B (3.4) BS01 rna ? GO:0003735 ... P80371 11163189
    12043 1hnw:C (3.4) BS01 rna ? GO:0003676 ... P80372 11163189
    12044 1hnw:D (3.4) BS01 rna ? GO:0003723 ... P80373 11163189
    12045 1hnw:D (3.4) BS02 MG ? GO:0003723 ... P80373 11163189
    12046 1hnw:D (3.4) BS03 ZN ? GO:0003723 ... P80373 11163189
    12047 1hnw:E (3.4) BS01 rna ? GO:0003723 ... Q5SHQ5 11163189
    12048 1hnw:F (3.4) BS01 rna ? GO:0003735 ... Q5SLP8 11163189
    12049 1hnw:G (3.4) BS01 rna ? GO:0000028 ... P17291 11163189
    12050 1hnw:H (3.4) BS01 rna ? GO:0003735 ... P0DOY9 11163189
    12051 1hnw:I (3.4) BS01 rna ? GO:0000049 ... P80374 11163189
    12052 1hnw:J (3.4) BS01 rna ? GO:0000049 ... Q5SHN7 11163189
    12053 1hnw:K (3.4) BS01 rna ? GO:0003735 ... P80376 11163189
    12054 1hnw:L (3.4) BS01 rna ? GO:0000049 ... Q5SHN3 11163189
    12055 1hnw:L (3.4) BS02 MG ? GO:0000049 ... Q5SHN3 11163189
    12056 1hnw:M (3.4) BS01 rna ? GO:0000049 ... P80377 11163189
    12057 1hnw:N (3.4) BS01 rna ? GO:0003735 ... P0DOY6 11163189
    12058 1hnw:N (3.4) BS02 ZN ? GO:0003735 ... P0DOY6 11163189
    12059 1hnw:O (3.4) BS01 rna ? GO:0003735 ... Q5SJ76 11163189
    12060 1hnw:P (3.4) BS01 rna ? GO:0003735 ... Q5SJH3 11163189
    12061 1hnw:Q (3.4) BS01 rna ? GO:0003735 ... P0DOY7 11163189
    12062 1hnw:R (3.4) BS01 rna ? GO:0003735 ... Q5SLQ0 11163189
    12063 1hnw:S (3.4) BS01 rna ? GO:0000028 ... Q5SHP2 11163189
    12064 1hnw:T (3.4) BS01 rna ? GO:0003723 ... P80380 11163189
    12065 1hnx:B (3.4) BS01 rna ? GO:0003735 ... P80371 11163189
    12066 1hnx:C (3.4) BS01 rna ? GO:0003676 ... P80372 11163189
    12067 1hnx:D (3.4) BS01 rna ? GO:0003723 ... P80373 11163189
    12068 1hnx:D (3.4) BS02 MG ? GO:0003723 ... P80373 11163189
    12069 1hnx:D (3.4) BS03 ZN ? GO:0003723 ... P80373 11163189
    12070 1hnx:E (3.4) BS01 rna ? GO:0003723 ... Q5SHQ5 11163189
    12071 1hnx:F (3.4) BS01 rna ? GO:0003735 ... Q5SLP8 11163189
    12072 1hnx:G (3.4) BS01 rna ? GO:0000028 ... P17291 11163189
    12073 1hnx:H (3.4) BS01 rna ? GO:0003735 ... P0DOY9 11163189
    12074 1hnx:I (3.4) BS01 rna ? GO:0000049 ... P80374 11163189
    12075 1hnx:J (3.4) BS01 rna ? GO:0000049 ... Q5SHN7 11163189
    12076 1hnx:K (3.4) BS01 rna ? GO:0003735 ... P80376 11163189
    12077 1hnx:L (3.4) BS01 rna ? GO:0000049 ... Q5SHN3 11163189
    12078 1hnx:M (3.4) BS01 rna ? GO:0000049 ... P80377 11163189
    12079 1hnx:N (3.4) BS01 rna ? GO:0003735 ... P0DOY6 11163189
    12080 1hnx:N (3.4) BS02 ZN ? GO:0003735 ... P0DOY6 11163189
    12081 1hnx:O (3.4) BS01 rna ? GO:0003735 ... Q5SJ76 11163189
    12082 1hnx:P (3.4) BS01 rna ? GO:0003735 ... Q5SJH3 11163189
    12083 1hnx:Q (3.4) BS01 rna ? GO:0003735 ... P0DOY7 11163189
    12084 1hnx:R (3.4) BS01 rna ? GO:0003735 ... Q5SLQ0 11163189
    12085 1hnx:S (3.4) BS01 rna ? GO:0000028 ... Q5SHP2 11163189
    12086 1hnx:T (3.4) BS01 rna ? GO:0003723 ... P80380 11163189
    12087 1hny:A (1.8) BS01 CA 3.2.1.1 GO:0003824 ... P04746 8528071
    12088 1hny:A (1.8) BS02 CL 3.2.1.1 GO:0003824 ... P04746 8528071
    12089 1hnz:B (3.3) BS01 rna ? GO:0003735 ... P80371 11163189
    12090 1hnz:C (3.3) BS01 rna ? GO:0003676 ... P80372 11163189
    12091 1hnz:D (3.3) BS01 rna ? GO:0003723 ... P80373 11163189
    12092 1hnz:D (3.3) BS02 MG ? GO:0003723 ... P80373 11163189
    12093 1hnz:E (3.3) BS01 rna ? GO:0003723 ... Q5SHQ5 11163189
    12094 1hnz:F (3.3) BS01 rna ? GO:0003735 ... Q5SLP8 11163189
    12095 1hnz:G (3.3) BS01 rna ? GO:0000028 ... P17291 11163189
    12096 1hnz:H (3.3) BS01 rna ? GO:0003735 ... P0DOY9 11163189
    12097 1hnz:I (3.3) BS01 rna ? GO:0000049 ... P80374 11163189
    12098 1hnz:J (3.3) BS01 rna ? GO:0000049 ... Q5SHN7 11163189
    12099 1hnz:K (3.3) BS01 rna ? GO:0003735 ... P80376 11163189
    12100 1hnz:L (3.3) BS01 rna ? GO:0000049 ... Q5SHN3 11163189
    12101 1hnz:M (3.3) BS01 rna ? GO:0000049 ... P80377 11163189
    12102 1hnz:N (3.3) BS01 rna ? GO:0003735 ... P0DOY6 11163189
    12103 1hnz:N (3.3) BS02 ZN ? GO:0003735 ... P0DOY6 11163189
    12104 1hnz:O (3.3) BS01 rna ? GO:0003735 ... Q5SJ76 11163189
    12105 1hnz:P (3.3) BS01 rna ? GO:0003735 ... Q5SJH3 11163189
    12106 1hnz:Q (3.3) BS01 rna ? GO:0003735 ... P0DOY7 11163189
    12107 1hnz:R (3.3) BS01 rna ? GO:0003735 ... Q5SLQ0 11163189
    12108 1hnz:S (3.3) BS01 rna ? GO:0000028 ... Q5SHP2 11163189
    12109 1hnz:T (3.3) BS01 rna ? GO:0003723 ... P80380 11163189
    12110 1ho3:A (2.5) BS01 ASP 3.5.1.1 GO:0004067 ... P00805 11223513
    12111 1ho3:B (2.5) BS01 ASP 3.5.1.1 GO:0004067 ... P00805 11223513
    12112 1ho4:A (2.3) BS01 PO4 2.6.99.2 GO:0005737 ... P0A794 11286891
    12113 1ho4:A (2.3) BS02 PXP 2.6.99.2 GO:0005737 ... P0A794 11286891
    12114 1ho4:B (2.3) BS01 PO4 2.6.99.2 GO:0005737 ... P0A794 11286891
    12115 1ho4:B (2.3) BS02 PXP 2.6.99.2 GO:0005737 ... P0A794 11286891
    12116 1ho4:C (2.3) BS01 PO4 2.6.99.2 GO:0005737 ... P0A794 11286891
    12117 1ho4:C (2.3) BS02 PXP 2.6.99.2 GO:0005737 ... P0A794 11286891
    12118 1ho4:D (2.3) BS01 PXP 2.6.99.2 GO:0005737 ... P0A794 11286891
    12119 1ho5:A (2.1) BS01 MN 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12120 1ho5:A (2.1) BS02 MN 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12121 1ho5:A (2.1) BS03 PO4 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12122 1ho5:A (2.1) BS04 ADN 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12123 1ho5:B (2.1) BS01 MN 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12124 1ho5:B (2.1) BS02 MN 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12125 1ho5:B (2.1) BS03 PO4 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12126 1ho5:B (2.1) BS04 ADN 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12127 1hon:A (2.3) BS01 GNH 6.3.4.4 GO:0000166 ... P0A7D4 8663109
    12128 1hoo:A (2.3) BS01 GNH 6.3.4.4 GO:0000166 ... P0A7D4 8663109
    12129 1hoo:A (2.3) BS02 GNP 6.3.4.4 GO:0000166 ... P0A7D4 8663109
    12130 1hor:A (2.4) BS01 AGP 3.5.99.6 GO:0004342 ... P0A759 8747459
    12131 1hor:B (2.4) BS01 AGP 3.5.99.6 GO:0004342 ... P0A759 8747459
    12132 1hot:A (2.4) BS01 PO4 3.5.99.6 GO:0004342 ... P0A759 8747459
    12133 1hov:A (-1.00) BS01 ZN 3.4.24.24 GO:0004222 ... P08253 12147339
    12134 1hov:A (-1.00) BS02 ZN 3.4.24.24 GO:0004222 ... P08253 12147339
    12135 1hov:A (-1.00) BS03 CA 3.4.24.24 GO:0004222 ... P08253 12147339
    12136 1hov:A (-1.00) BS04 CA 3.4.24.24 GO:0004222 ... P08253 12147339
    12137 1hov:A (-1.00) BS05 I52 3.4.24.24 GO:0004222 ... P08253 12147339 BindingDB: IC50=<0.100000nM
    12138 1hox:A (2.1) BS01 F6P 5.3.1.9 GO:0004347 ... Q9N1E2 11425306
    12139 1hox:B (2.1) BS01 F6P 5.3.1.9 GO:0004347 ... Q9N1E2 11425306
    12140 1hoy:A (-1.00) BS01 peptide ? GO:0005515 ... P60615 11814338
    12141 1hp1:A (1.7) BS01 ZN 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12142 1hp1:A (1.7) BS02 ZN 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12143 1hp1:A (1.7) BS03 CO3 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12144 1hp1:A (1.7) BS04 ATP 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12145 1hp5:A (2.1) BS01 NGT 3.2.1.52 GO:0004553 ... O85361 11124970 PDBbind: -logKd/Ki=6.55, Ki=280nM
    BindingDB: Ki=20000nM
    12146 1hp7:A (2.1) BS01 ZN ? GO:0002020 ... P01009 11178897
    12147 1hp7:A (2.1) BS02 ZN ? GO:0002020 ... P01009 11178897
    12148 1hp7:A (2.1) BS03 ZN ? GO:0002020 ... P01009 11178897
    12149 1hp7:A (2.1) BS04 ZN ? GO:0002020 ... P01009 11178897
    12150 1hpc:A (2.0) BS01 LPB 1.4.4.2 GO:0005960 ... P16048 15299773
    12151 1hpc:B (2.0) BS01 LPA 1.4.4.2 GO:0005960 ... P16048 15299773
    12152 1hpl:A (2.3) BS01 CA 3.1.1.3 GO:0004806 ... P29183 8182745
    12153 1hpl:B (2.3) BS01 CA 3.1.1.3 GO:0004806 ... P29183 8182745
    12154 1hpu:A (1.85) BS01 MN 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12155 1hpu:A (1.85) BS02 MN 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12156 1hpu:A (1.85) BS03 A12 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12157 1hpu:B (1.85) BS01 MN 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12158 1hpu:B (1.85) BS02 MN 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12159 1hpu:B (1.85) BS03 A12 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12160 1hpu:C (1.85) BS01 MN 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12161 1hpu:C (1.85) BS02 MN 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12162 1hpu:C (1.85) BS03 A12 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12163 1hpu:D (1.85) BS01 MN 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12164 1hpu:D (1.85) BS02 MN 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12165 1hpu:D (1.85) BS03 A12 3.1.3.5
    3.6.1.45
    GO:0000166 ... P07024 11491293
    12166 1hq1:A (1.52) BS01 rna 3.6.5.4 GO:0003924 ... P0AGD7 11243816 PDBbind: Kd=33pM
    12167 1hq3:A (2.15) BS01 PO4 ? GO:0000786 ... P02263 12876341
    12168 1hq3:C (2.15) BS01 PO4 ? GO:0000122 ... P84229 12876341
    12169 1hq3:E (2.15) BS01 PO4 ? GO:0000786 ... P02263 12876341
    12170 1hq5:A (2.3) BS01 MN 3.5.3.1 GO:0000050 ... P07824 11258879
    12171 1hq5:A (2.3) BS02 MN 3.5.3.1 GO:0000050 ... P07824 11258879
    12172 1hq5:A (2.3) BS03 S2C 3.5.3.1 GO:0000050 ... P07824 11258879 MOAD: Kd=2.22uM
    PDBbind: -logKd/Ki=5.65, Kd=2.22uM
    12173 1hq5:B (2.3) BS01 MN 3.5.3.1 GO:0000050 ... P07824 11258879
    12174 1hq5:B (2.3) BS02 MN 3.5.3.1 GO:0000050 ... P07824 11258879
    12175 1hq5:B (2.3) BS03 S2C 3.5.3.1 GO:0000050 ... P07824 11258879 MOAD: Kd=2.22uM
    12176 1hqa:A (2.25) BS01 ZN 3.1.3.1 GO:0000287 ... P00634 8652582
    12177 1hqa:A (2.25) BS02 ZN 3.1.3.1 GO:0000287 ... P00634 8652582
    12178 1hqa:A (2.25) BS03 ZN 3.1.3.1 GO:0000287 ... P00634 8652582
    12179 1hqa:B (2.25) BS01 ZN 3.1.3.1 GO:0000287 ... P00634 8652582
    12180 1hqa:B (2.25) BS02 ZN 3.1.3.1 GO:0000287 ... P00634 8652582
    12181 1hqa:B (2.25) BS03 ZN 3.1.3.1 GO:0000287 ... P00634 8652582
    12182 1hqc:A (3.2) BS01 ADE 3.6.4.12 GO:0000400 ... Q5SL87 11171970
    12183 1hqc:B (3.2) BS01 ADE 3.6.4.12 GO:0000400 ... Q5SL87 11171970
    12184 1hqd:A (2.3) BS01 CA 3.1.1.3 GO:0004806 ... P22088 11453990
    12185 1hqd:A (2.3) BS02 INK 3.1.1.3 GO:0004806 ... P22088 11453990
    12186 1hqf:A (2.9) BS01 MN 3.5.3.1 GO:0000050 ... P07824 11258880
    12187 1hqf:A (2.9) BS02 MN 3.5.3.1 GO:0000050 ... P07824 11258880
    12188 1hqf:A (2.9) BS03 HAR 3.5.3.1 GO:0000050 ... P07824 11258880 PDBbind: -logKd/Ki=5.00, Ki=10uM
    12189 1hqf:B (2.9) BS01 MN 3.5.3.1 GO:0000050 ... P07824 11258880
    12190 1hqf:B (2.9) BS02 MN 3.5.3.1 GO:0000050 ... P07824 11258880
    12191 1hqf:B (2.9) BS03 HAR 3.5.3.1 GO:0000050 ... P07824 11258880
    12192 1hqf:C (2.9) BS01 MN 3.5.3.1 GO:0000050 ... P07824 11258880
    12193 1hqf:C (2.9) BS02 MN 3.5.3.1 GO:0000050 ... P07824 11258880
    12194 1hqf:C (2.9) BS03 HAR 3.5.3.1 GO:0000050 ... P07824 11258880
    12195 1hqg:A (2.0) BS01 MN 3.5.3.1 GO:0000050 ... P07824 11258880
    12196 1hqg:A (2.0) BS02 MN 3.5.3.1 GO:0000050 ... P07824 11258880
    12197 1hqg:A (2.0) BS03 ORN 3.5.3.1 GO:0000050 ... P07824 11258880 PDBbind: -logKd/Ki=3.00, Ki=1.0mM
    12198 1hqg:A (2.0) BS04 URE 3.5.3.1 GO:0000050 ... P07824 11258880
    12199 1hqg:B (2.0) BS01 MN 3.5.3.1 GO:0000050 ... P07824 11258880
    12200 1hqg:B (2.0) BS02 MN 3.5.3.1 GO:0000050 ... P07824 11258880

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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