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BioLiP
Download all results in tab-seperated text for 594392 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    57001 2k91:B (-1.00) BS01 peptide ? GO:0005179 ... P01308 19321436
    57002 2k9c:A (-1.00) BS01 CO 3.4.24.65 GO:0004222 ... P39900 18988744
    57003 2k9r:B (-1.00) BS01 peptide ? GO:0005179 ... P01308 19321436
    57004 2kau:C (2.0) BS01 NI 3.5.1.5 GO:0005515 ... P18314 7754395
    57005 2kau:C (2.0) BS02 NI 3.5.1.5 GO:0005515 ... P18314 7754395
    57006 2kay:A (-1.00) BS01 CA ? GO:0005507 ... P33763 19536568
    57007 2kay:A (-1.00) BS02 CA ? GO:0005507 ... P33763 19536568
    57008 2kay:B (-1.00) BS01 CA ? GO:0005507 ... P33763 19536568
    57009 2kay:B (-1.00) BS02 CA ? GO:0005507 ... P33763 19536568
    57010 2kbm:A (-1.00) BS01 peptide ? GO:0000122 ... P35467 N/A
    57011 2kbm:A (-1.00) BS02 CA ? GO:0000122 ... P35467 N/A
    57012 2kbm:A (-1.00) BS03 CA ? GO:0000122 ... P35467 N/A
    57013 2kbm:B (-1.00) BS01 peptide ? GO:0000122 ... P35467 N/A
    57014 2kbm:B (-1.00) BS02 CA ? GO:0000122 ... P35467 N/A
    57015 2kbm:B (-1.00) BS03 CA ? GO:0000122 ... P35467 N/A
    57016 2kce:A (2.2) BS01 UMP 2.1.1.45 GO:0000287 ... P0A884 8939755
    57017 2kce:A (2.2) BS02 D16 2.1.1.45 GO:0000287 ... P0A884 8939755 MOAD: Ki=0.67uM
    PDBbind: -logKd/Ki=6.17, Ki=0.67uM
    BindingDB: IC50=2300nM
    57018 2kce:A (2.2) BS03 UMP 2.1.1.45 GO:0000287 ... P0A884 8939755
    57019 2kce:B (2.2) BS01 UMP 2.1.1.45 GO:0000287 ... P0A884 8939755
    57020 2kce:B (2.2) BS02 UMP 2.1.1.45 GO:0000287 ... P0A884 8939755
    57021 2kce:B (2.2) BS03 D16 2.1.1.45 GO:0000287 ... P0A884 8939755 MOAD: Ki=0.67uM
    PDBbind: -logKd/Ki=6.17, Ki=0.67uM
    BindingDB: IC50=2300nM
    57022 2ke5:A (-1.00) BS01 GNP 3.6.5.2 GO:0003924 ... P11234 19166349
    57023 2kg6:A (-1.00) BS01 SXA ? GO:0000035 ... Q02054 19361520
    57024 2kg8:A (-1.00) BS01 SXM ? GO:0000035 ... Q02054 19361520
    57025 2kg9:A (-1.00) BS01 PSR ? GO:0000035 ... Q02054 19361520
    57026 2kga:A (-1.00) BS01 SXH ? GO:0000035 ... Q02054 19361520
    57027 2kgc:A (-1.00) BS01 SXO ? GO:0000035 ... Q02054 19361520
    57028 2kgd:A (-1.00) BS01 SXV ? GO:0000035 ... Q02054 19361520
    57029 2kge:A (-1.00) BS01 SXD ? GO:0000035 ... Q02054 19361520
    57030 2kgk:A (-1.00) BS01 NAP 1.5.1.3 GO:0000166 ... Q81R22 19323450
    57031 2kgk:A (-1.00) BS02 N22 1.5.1.3 GO:0000166 ... Q81R22 19323450 BindingDB: IC50=890nM, Ki=300nM
    57032 2khh:A (-1.00) BS01 peptide ? GO:0005634 ... Q99257 19401465
    57033 2ki7:B (-1.00) BS01 ZN 3.1.26.5 GO:0001682 ... Q8U0H6 19733182
    57034 2kii:A (-1.00) BS01 HEM ? GO:0003674 ... Q8EF49 19918063
    57035 2kil:A (-1.00) BS01 HEM ? GO:0003674 ... Q8EF49 19918063
    57036 2kjj:B (-1.00) BS01 peptide ? GO:0005179 ... P01308 N/A
    57037 2kju:B (-1.00) BS01 peptide ? GO:0005179 ... P01308 N/A
    57038 2kkd:A (-1.00) BS01 NI ? GO:0005506 ... P00269 19997764
    57039 2km0:A (-1.00) BS01 CU1 ? GO:0042597 ... Q58AD3 20192263
    57040 2kne:A (-1.00) BS01 peptide ? GO:0000086 ... P0DP23 19996092
    57041 2kne:A (-1.00) BS02 CA ? GO:0000086 ... P0DP23 19996092
    57042 2kne:A (-1.00) BS03 CA ? GO:0000086 ... P0DP23 19996092
    57043 2kne:A (-1.00) BS04 CA ? GO:0000086 ... P0DP23 19996092
    57044 2kne:A (-1.00) BS05 CA ? GO:0000086 ... P0DP23 19996092
    57045 2ko8:A (-1.00) BS01 ZN ? GO:0005515 ... O31466 N/A
    57046 2ko8:B (-1.00) BS01 ZN ? GO:0005515 ... O31466 N/A
    57047 2ko8:C (-1.00) BS01 ZN ? GO:0005515 ... O31466 N/A
    57048 2koo:A (-1.00) BS01 SXH ? GO:0000035 ... P72393 20659690
    57049 2kop:A (-1.00) BS01 SYO ? GO:0000035 ... P72393 20659690
    57050 2koq:A (-1.00) BS01 SHW ? GO:0000035 ... P72393 20659690
    57051 2kor:A (-1.00) BS01 SOO ? GO:0000035 ... P72393 20659690
    57052 2kos:A (-1.00) BS01 SXO ? GO:0000035 ... P72393 20659690
    57053 2kot:A (-1.00) BS01 ANW ? GO:0001819 ... Q99584 20178375
    57054 2kot:B (-1.00) BS01 ANW ? GO:0001819 ... Q99584 20178375
    57055 2kpi:A (-1.00) BS01 ZN ? GO:0005829 ... Q9KZL7 N/A
    57056 2kpn:A (-1.00) BS01 CA 3.4.24.28 GO:0005509 ... Q81D73 N/A
    57057 2kqq:B (-1.00) BS01 peptide ? GO:0005179 ... P01308 N/A
    57058 2kqs:A (-1.00) BS01 peptide ? GO:0001741 ... P63165 21474068
    57059 2krb:A (-1.00) BS01 peptide ? GO:0003676 ... P55884 N/A
    57060 2krj:A (-1.00) BS01 CO 3.4.24.65 GO:0004222 ... P39900 20041641
    57061 2ks9:A (-1.00) BS01 peptide ? GO:0004930 ... P25103 20937248
    57062 2ksa:A (-1.00) BS01 peptide ? GO:0004930 ... P25103 20937248
    57063 2ksb:A (-1.00) BS01 peptide ? GO:0004930 ... P25103 20937248
    57064 2ksq:A (-1.00) BS01 MTN 3.6.5.2 GO:0003924 ... P11076 20601958
    57065 2ksq:A (-1.00) BS02 MTN 3.6.5.2 GO:0003924 ... P11076 20601958
    57066 2ksq:A (-1.00) BS03 GTP 3.6.5.2 GO:0003924 ... P11076 20601958
    57067 2ksy:A (-1.00) BS01 RET N/A GO:0005216 ... N/A 20512150
    57068 2kt4:B (-1.00) BS01 EB4 ? GO:0005576 ... Q9I9P7 20826777
    57069 2ktb:B (-1.00) BS01 peptide ? GO:0006338 ... Q86U86 20368734
    57070 2ktd:A (-1.00) BS01 PUC 5.3.99.2 GO:0001516 ... O09114 N/A
    57071 2kug:A (-1.00) BS01 CA ? GO:0000086 ... P0DP23 N/A
    57072 2kug:A (-1.00) BS02 CA ? GO:0000086 ... P0DP23 N/A
    57073 2kug:A (-1.00) BS03 HLT ? GO:0000086 ... P0DP23 N/A
    57074 2kvm:A (-1.00) BS01 peptide ? GO:0035102 ... Q8VDS3 20541999
    57075 2kwi:A (-1.00) BS01 GNP 3.6.5.2 GO:0003924 ... P11234 20696399
    57076 2kwi:A (-1.00) BS02 MG 3.6.5.2 GO:0003924 ... P11234 20696399
    57077 2kxk:B (-1.00) BS01 peptide ? GO:0005179 ... P01308 21704065
    57078 2kyf:A (-1.00) BS01 CA ? GO:0005509 ... P43305 21287610
    57079 2kyf:A (-1.00) BS02 CA ? GO:0005509 ... P43305 21287610
    57080 2l0x:A (-1.00) BS01 MG 3.6.5.- GO:0000139 ... Q62639 20685651
    57081 2l0x:A (-1.00) BS02 GDP 3.6.5.- GO:0000139 ... Q62639 20685651
    57082 2l0y:A (-1.00) BS01 peptide ? GO:0005515 ... Q8N4Q1 21059946
    57083 2l0z:A (-1.00) BS01 ZN ? GO:0019031 ... P26313 21068387
    57084 2l0z:A (-1.00) BS02 ZN ? GO:0019031 ... P26313 21068387
    57085 2l12:A (-1.00) BS01 peptide ? GO:0035102 ... O95931 21047797
    57086 2l1b:A (-1.00) BS01 peptide ? GO:0035102 ... O95931 21047797
    57087 2l1y:B (-1.00) BS01 peptide ? GO:0005179 ... P01308 N/A
    57088 2l1z:B (-1.00) BS01 peptide ? GO:0005179 ... P01308 N/A
    57089 2l4h:A (-1.00) BS01 CA ? GO:0000287 ... Q99828 21388953
    57090 2l4h:A (-1.00) BS02 CA ? GO:0000287 ... Q99828 21388953
    57091 2l4i:A (-1.00) BS01 MG ? GO:0000287 ... Q99828 21388953
    57092 2l4t:A (-1.00) BS01 peptide ? GO:0001650 ... O14907 21417405
    57093 2l51:A (-1.00) BS01 CA ? GO:0003723 ... Q96FQ6 21046186
    57094 2l51:A (-1.00) BS02 CA ? GO:0003723 ... Q96FQ6 21046186
    57095 2l51:B (-1.00) BS01 CA ? GO:0003723 ... Q96FQ6 21046186
    57096 2l51:B (-1.00) BS02 CA ? GO:0003723 ... Q96FQ6 21046186
    57097 2l6j:A (-1.00) BS01 peptide ? GO:0000492 ... P25638 22179618
    57098 2l6l:A (-1.00) BS01 ZN ? GO:0001671 ... Q6P3W2 22367199
    57099 2l6x:A (-1.00) BS01 RET ? GO:0005216 ... Q9F7P4 22034093
    57100 2l7l:A (-1.00) BS01 peptide ? GO:0000086 ... P0DP23 21360154
    57101 2l7l:A (-1.00) BS02 CA ? GO:0000086 ... P0DP23 21360154
    57102 2l7l:A (-1.00) BS03 CA ? GO:0000086 ... P0DP23 21360154
    57103 2l7l:A (-1.00) BS04 CA ? GO:0000086 ... P0DP23 21360154
    57104 2l7l:A (-1.00) BS05 CA ? GO:0000086 ... P0DP23 21360154
    57105 2l8e:A (-1.00) BS01 ZN ? GO:0005634 ... P78364 N/A
    57106 2l8j:A (-1.00) BS01 peptide ? GO:0000045 ... Q9H0R8 21620860
    57107 2l8m:A (-1.00) BS01 CAM 1.14.15.1 GO:0004497 ... P00183 21265500
    57108 2l8m:A (-1.00) BS02 HEM 1.14.15.1 GO:0004497 ... P00183 21265500
    57109 2l8r:A (-1.00) BS01 APR 3.2.2.-
    3.5.1.-
    GO:0001883 ... Q9Y530 21849506 PDBbind: -logKd/Ki=3.92, Ki=119.3uM
    57110 2las:A (-1.00) BS01 peptide ? GO:0001741 ... P63165 22147707
    57111 2lba:A (-1.00) BS01 CHO ? GO:0005504 ... F1NUJ7 21917914
    57112 2lba:A (-1.00) BS02 CHO ? GO:0005504 ... F1NUJ7 21917914
    57113 2lbd:A (2.06) BS01 REA ? GO:0003677 ... P13631 7501014
    57114 2lbv:A (-1.00) BS01 EB4 ? GO:0005576 ... Q9I9P7 21951132
    57115 2lbv:A (-1.00) BS02 ACD ? GO:0005576 ... Q9I9P7 21951132 PDBbind: -logKd/Ki=7.59, Kd=26nM
    57116 2lcf:A (-1.00) BS01 GNP 3.6.5.2 GO:0003924 ... P01112 21930707
    57117 2lcp:A (-1.00) BS01 CA ? GO:0005245 ... P62166 22227393
    57118 2lcp:A (-1.00) BS02 CA ? GO:0005245 ... P62166 22227393
    57119 2lcp:A (-1.00) BS03 CA ? GO:0005245 ... P62166 22227393
    57120 2lcq:A (-1.00) BS01 ZN 3.1.-.- GO:0000287 ... O58440 22156373
    57121 2ldb:A (3.0) BS01 SO4 1.1.1.27 GO:0003824 ... P00344 2330370
    57122 2ldb:A (3.0) BS02 SO4 1.1.1.27 GO:0003824 ... P00344 2330370
    57123 2ldb:A (3.0) BS03 NAD 1.1.1.27 GO:0003824 ... P00344 2330370
    57124 2ldb:A (3.0) BS04 FBP 1.1.1.27 GO:0003824 ... P00344 2330370
    57125 2ldb:B (3.0) BS01 SO4 1.1.1.27 GO:0003824 ... P00344 2330370
    57126 2ldb:B (3.0) BS02 SO4 1.1.1.27 GO:0003824 ... P00344 2330370
    57127 2ldb:B (3.0) BS03 NAD 1.1.1.27 GO:0003824 ... P00344 2330370
    57128 2ldb:B (3.0) BS04 FBP 1.1.1.27 GO:0003824 ... P00344 2330370
    57129 2ldb:C (3.0) BS01 FBP 1.1.1.27 GO:0003824 ... P00344 2330370
    57130 2ldb:C (3.0) BS02 SO4 1.1.1.27 GO:0003824 ... P00344 2330370
    57131 2ldb:C (3.0) BS03 SO4 1.1.1.27 GO:0003824 ... P00344 2330370
    57132 2ldb:C (3.0) BS04 NAD 1.1.1.27 GO:0003824 ... P00344 2330370
    57133 2ldb:D (3.0) BS01 FBP 1.1.1.27 GO:0003824 ... P00344 2330370
    57134 2ldb:D (3.0) BS02 SO4 1.1.1.27 GO:0003824 ... P00344 2330370
    57135 2ldb:D (3.0) BS03 SO4 1.1.1.27 GO:0003824 ... P00344 2330370
    57136 2ldb:D (3.0) BS04 NAD 1.1.1.27 GO:0003824 ... P00344 2330370
    57137 2leg:B (-1.00) BS01 UQ1 ? GO:0005515 ... P0A6M2 21938394
    57138 2lel:A (-1.00) BS01 CU1 ? GO:0042597 ... Q58AD3 21936507
    57139 2lel:A (-1.00) BS02 CU ? GO:0042597 ... Q58AD3 21936507
    57140 2lf1:A (-1.00) BS01 NDP 1.5.1.3 GO:0004146 ... P00381 21410224
    57141 2lfo:A (-1.00) BS01 GCH ? GO:0005504 ... P80226 22298334
    57142 2lfo:A (-1.00) BS02 CHO ? GO:0005504 ... P80226 22298334
    57143 2lgb:B (-1.00) BS01 peptide ? GO:0005179 ... P01308 22350952
    57144 2lgf:A (-1.00) BS01 peptide ? GO:0000086 ... P0DP23 22711531
    57145 2lgf:A (-1.00) BS02 CA ? GO:0000086 ... P0DP23 22711531
    57146 2lgf:A (-1.00) BS03 CA ? GO:0000086 ... P0DP23 22711531
    57147 2lgf:A (-1.00) BS04 CA ? GO:0000086 ... P0DP23 22711531
    57148 2lgf:A (-1.00) BS05 CA ? GO:0000086 ... P0DP23 22711531
    57149 2lgs:A (2.8) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57150 2lgs:A (2.8) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57151 2lgs:A (2.8) BS03 GLU 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57152 2lgs:B (2.8) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57153 2lgs:B (2.8) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57154 2lgs:B (2.8) BS03 GLU 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57155 2lgs:C (2.8) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57156 2lgs:C (2.8) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57157 2lgs:C (2.8) BS03 GLU 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57158 2lgs:D (2.8) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57159 2lgs:D (2.8) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57160 2lgs:D (2.8) BS03 GLU 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57161 2lgs:E (2.8) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57162 2lgs:E (2.8) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57163 2lgs:E (2.8) BS03 GLU 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57164 2lgs:F (2.8) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57165 2lgs:F (2.8) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57166 2lgs:F (2.8) BS03 GLU 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57167 2lgs:G (2.8) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57168 2lgs:G (2.8) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57169 2lgs:G (2.8) BS03 GLU 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57170 2lgs:H (2.8) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57171 2lgs:H (2.8) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57172 2lgs:H (2.8) BS03 GLU 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57173 2lgs:I (2.8) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57174 2lgs:I (2.8) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57175 2lgs:I (2.8) BS03 GLU 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57176 2lgs:J (2.8) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57177 2lgs:J (2.8) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57178 2lgs:J (2.8) BS03 GLU 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57179 2lgs:K (2.8) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57180 2lgs:K (2.8) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57181 2lgs:K (2.8) BS03 GLU 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57182 2lgs:L (2.8) BS01 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57183 2lgs:L (2.8) BS02 MN 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57184 2lgs:L (2.8) BS03 GLU 6.3.1.2 GO:0003824 ... P0A1P6 8099447
    57185 2lgv:A (-1.00) BS01 ZN 2.3.2.27
    2.3.2.32
    GO:0000165 ... P62877 22433864
    57186 2lgv:A (-1.00) BS02 ZN 2.3.2.27
    2.3.2.32
    GO:0000165 ... P62877 22433864
    57187 2lgv:A (-1.00) BS03 ZN 2.3.2.27
    2.3.2.32
    GO:0000165 ... P62877 22433864
    57188 2lh1:A (2.0) BS01 HEM ? GO:0005344 ... P02240 N/A
    57189 2lh2:A (2.0) BS01 HEM ? GO:0005344 ... P02240 N/A
    57190 2lh3:A (2.0) BS01 HEM ? GO:0005344 ... P02240 N/A
    57191 2lh5:A (2.0) BS01 HEM ? GO:0005344 ... P02240 N/A
    57192 2lh6:A (2.0) BS01 HEM ? GO:0005344 ... P02240 N/A
    57193 2lh6:A (2.0) BS02 NIO ? GO:0005344 ... P02240 N/A
    57194 2lh7:A (2.0) BS01 HEM ? GO:0005344 ... P02240 N/A
    57195 2lh7:A (2.0) BS02 NBE ? GO:0005344 ... P02240 N/A
    57196 2lh8:A (-1.00) BS01 VIB ? GO:0016020 ... P04273 21848803 PDBbind: -logKd/Ki=4.18, Kd=65.36uM
    57197 2lha:A (-1.00) BS01 IHP ? GO:0016020 ... P21579 22475172 PDBbind: -logKd/Ki=5.19, Kd=6.4uM
    57198 2lhi:A (-1.00) BS01 CA ?
    3.1.3.16
    GO:0000131 ... P06787
    P23287
    22280008
    57199 2lhi:A (-1.00) BS02 CA ?
    3.1.3.16
    GO:0000131 ... P06787
    P23287
    22280008
    57200 2lhi:A (-1.00) BS03 CA ?
    3.1.3.16
    GO:0000131 ... P06787
    P23287
    22280008

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218