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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
Download all results in tab-seperated text for 594392 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    31801 1so0:A (2.3) BS01 GAL 5.1.3.3 GO:0003824 ... Q96C23 15026423
    31802 1so0:B (2.3) BS01 GAL 5.1.3.3 GO:0003824 ... Q96C23 15026423
    31803 1so0:C (2.3) BS01 GAL 5.1.3.3 GO:0003824 ... Q96C23 15026423
    31804 1so0:D (2.3) BS01 GAL 5.1.3.3 GO:0003824 ... Q96C23 15026423
    31805 1sof:A (2.6) BS01 FE2 1.16.3.1 GO:0004322 ... P22759 15327981
    31806 1sof:A (2.6) BS02 FE2 1.16.3.1 GO:0004322 ... P22759 15327981
    31807 1sof:A (2.6) BS03 HEM 1.16.3.1 GO:0004322 ... P22759 15327981
    31808 1sof:B (2.6) BS01 FE2 1.16.3.1 GO:0004322 ... P22759 15327981
    31809 1sof:B (2.6) BS02 FE2 1.16.3.1 GO:0004322 ... P22759 15327981
    31810 1sof:B (2.6) BS03 HEM 1.16.3.1 GO:0004322 ... P22759 15327981
    31811 1sof:C (2.6) BS01 FE2 1.16.3.1 GO:0004322 ... P22759 15327981
    31812 1sof:C (2.6) BS02 FE2 1.16.3.1 GO:0004322 ... P22759 15327981
    31813 1sof:C (2.6) BS03 HEM 1.16.3.1 GO:0004322 ... P22759 15327981
    31814 1sof:D (2.6) BS01 HEM 1.16.3.1 GO:0004322 ... P22759 15327981
    31815 1sof:D (2.6) BS02 FE2 1.16.3.1 GO:0004322 ... P22759 15327981
    31816 1sof:D (2.6) BS03 FE2 1.16.3.1 GO:0004322 ... P22759 15327981
    31817 1sof:E (2.6) BS01 FE2 1.16.3.1 GO:0004322 ... P22759 15327981
    31818 1sof:E (2.6) BS02 FE2 1.16.3.1 GO:0004322 ... P22759 15327981
    31819 1sof:E (2.6) BS03 HEM 1.16.3.1 GO:0004322 ... P22759 15327981
    31820 1sof:F (2.6) BS01 HEM 1.16.3.1 GO:0004322 ... P22759 15327981
    31821 1sof:F (2.6) BS02 FE2 1.16.3.1 GO:0004322 ... P22759 15327981
    31822 1sof:F (2.6) BS03 FE2 1.16.3.1 GO:0004322 ... P22759 15327981
    31823 1sof:G (2.6) BS01 FE2 1.16.3.1 GO:0004322 ... P22759 15327981
    31824 1sof:G (2.6) BS02 FE2 1.16.3.1 GO:0004322 ... P22759 15327981
    31825 1sof:G (2.6) BS03 HEM 1.16.3.1 GO:0004322 ... P22759 15327981
    31826 1sof:H (2.6) BS01 HEM 1.16.3.1 GO:0004322 ... P22759 15327981
    31827 1sof:H (2.6) BS02 FE2 1.16.3.1 GO:0004322 ... P22759 15327981
    31828 1sof:H (2.6) BS03 FE2 1.16.3.1 GO:0004322 ... P22759 15327981
    31829 1som:A (2.2) BS01 VXA 3.1.1.7 GO:0001507 ... P04058 10353814
    31830 1son:A (2.55) BS01 AMP 6.3.4.4 GO:0000166 ... P0A7D4 8790347
    31831 1soo:A (2.6) BS01 H5P 6.3.4.4 GO:0000166 ... P0A7D4 8790347
    31832 1sos:A (2.5) BS01 CU 1.15.1.1 GO:0000302 ... P00441 1463506
    31833 1sos:A (2.5) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 1463506
    31834 1sos:B (2.5) BS01 CU 1.15.1.1 GO:0000302 ... P00441 1463506
    31835 1sos:B (2.5) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 1463506
    31836 1sos:C (2.5) BS01 CU 1.15.1.1 GO:0000302 ... P00441 1463506
    31837 1sos:C (2.5) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 1463506
    31838 1sos:D (2.5) BS01 CU 1.15.1.1 GO:0000302 ... P00441 1463506
    31839 1sos:D (2.5) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 1463506
    31840 1sos:E (2.5) BS01 CU 1.15.1.1 GO:0000302 ... P00441 1463506
    31841 1sos:E (2.5) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 1463506
    31842 1sos:F (2.5) BS01 CU 1.15.1.1 GO:0000302 ... P00441 1463506
    31843 1sos:F (2.5) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 1463506
    31844 1sos:G (2.5) BS01 CU 1.15.1.1 GO:0000302 ... P00441 1463506
    31845 1sos:G (2.5) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 1463506
    31846 1sos:H (2.5) BS01 CU 1.15.1.1 GO:0000302 ... P00441 1463506
    31847 1sos:H (2.5) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 1463506
    31848 1sos:I (2.5) BS01 CU 1.15.1.1 GO:0000302 ... P00441 1463506
    31849 1sos:I (2.5) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 1463506
    31850 1sos:J (2.5) BS01 CU 1.15.1.1 GO:0000302 ... P00441 1463506
    31851 1sos:J (2.5) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 1463506
    31852 1sox:A (1.9) BS01 SO4 1.8.3.1 GO:0005739 ... P07850 9428520
    31853 1sox:A (1.9) BS02 HEM 1.8.3.1 GO:0005739 ... P07850 9428520
    31854 1sox:B (1.9) BS01 SO4 1.8.3.1 GO:0005739 ... P07850 9428520
    31855 1sox:B (1.9) BS02 MO 1.8.3.1 GO:0005739 ... P07850 9428520
    31856 1sox:B (1.9) BS03 HEM 1.8.3.1 GO:0005739 ... P07850 9428520
    31857 1sp9:A (3.0) BS01 FE2 1.13.11.27 GO:0003868 ... P93836 15084729
    31858 1sp9:B (3.0) BS01 FE2 1.13.11.27 GO:0003868 ... P93836 15084729
    31859 1spa:A (2.0) BS01 NPL 2.6.1.1 GO:0003824 ... P00509 1610831
    31860 1spd:A (2.4) BS01 CU 1.15.1.1 GO:0000302 ... P00441 8351519
    31861 1spd:A (2.4) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 8351519
    31862 1spd:B (2.4) BS01 CU 1.15.1.1 GO:0000302 ... P00441 8351519
    31863 1spd:B (2.4) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 8351519
    31864 1spe:A (2.0) BS01 HEM 1.11.1.-
    1.7.-.-
    GO:0004601 ... P02185 8642596
    31865 1spg:A (1.95) BS01 HEM ? GO:0004601 ... P56250 8605630
    31866 1spg:B (1.95) BS01 HEM ? GO:0004601 ... P56251 8605630
    31867 1spj:A (1.7) BS01 CA 3.4.21.35 GO:0003073 ... P06870 15651049
    31868 1spu:A (2.0) BS01 CU 1.4.3.21 GO:0005507 ... P46883 9048544
    31869 1spu:A (2.0) BS02 CA 1.4.3.21 GO:0005507 ... P46883 9048544
    31870 1spu:A (2.0) BS03 CA 1.4.3.21 GO:0005507 ... P46883 9048544
    31871 1spu:B (2.0) BS01 CU 1.4.3.21 GO:0005507 ... P46883 9048544
    31872 1spu:B (2.0) BS02 CA 1.4.3.21 GO:0005507 ... P46883 9048544
    31873 1spu:B (2.0) BS03 CA 1.4.3.21 GO:0005507 ... P46883 9048544
    31874 1sq3:A (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    31875 1sq3:A (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    31876 1sq3:A (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    31877 1sq3:B (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    31878 1sq3:B (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    31879 1sq3:B (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    31880 1sq3:C (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    31881 1sq3:C (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    31882 1sq3:C (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    31883 1sq3:D (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    31884 1sq3:D (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    31885 1sq3:D (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    31886 1sq3:E (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    31887 1sq3:E (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    31888 1sq3:E (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    31889 1sq3:F (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    31890 1sq3:F (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    31891 1sq3:F (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    31892 1sq3:G (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    31893 1sq3:G (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    31894 1sq3:G (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    31895 1sq3:H (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    31896 1sq3:H (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    31897 1sq3:H (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    31898 1sq3:I (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    31899 1sq3:I (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    31900 1sq3:I (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    31901 1sq3:J (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    31902 1sq3:J (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    31903 1sq3:J (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    31904 1sq3:K (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    31905 1sq3:K (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    31906 1sq3:K (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    31907 1sq3:L (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    31908 1sq3:L (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    31909 1sq3:L (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    31910 1sq5:A (2.2) BS01 PAU 2.7.1.33 GO:0004594 ... P0A6I3 15136582
    31911 1sq5:A (2.2) BS02 ADP 2.7.1.33 GO:0004594 ... P0A6I3 15136582
    31912 1sq5:B (2.2) BS01 PAU 2.7.1.33 GO:0004594 ... P0A6I3 15136582
    31913 1sq5:B (2.2) BS02 ADP 2.7.1.33 GO:0004594 ... P0A6I3 15136582
    31914 1sq5:C (2.2) BS01 PAU 2.7.1.33 GO:0004594 ... P0A6I3 15136582
    31915 1sq5:C (2.2) BS02 ADP 2.7.1.33 GO:0004594 ... P0A6I3 15136582
    31916 1sq5:D (2.2) BS01 PAU 2.7.1.33 GO:0004594 ... P0A6I3 15136582
    31917 1sq5:D (2.2) BS02 ADP 2.7.1.33 GO:0004594 ... P0A6I3 15136582
    31918 1sq6:A (2.4) BS01 SO4 2.4.2.1
    2.4.2.44
    GO:0003824 ... Q8I3X4 16131758
    31919 1sqb:C (2.69) BS01 HEM 1.10.2.2 GO:0005739 ... P00157 15312779
    31920 1sqb:C (2.69) BS02 HEM 1.10.2.2 GO:0005739 ... P00157 15312779
    31921 1sqb:C (2.69) BS03 AZO 1.10.2.2 GO:0005739 ... P00157 15312779 PDBbind: -logKd/Ki=7.95, IC50=11.2nM
    31922 1sqb:E (2.69) BS01 FES 7.1.1.8 GO:0008121 ... P13272 15312779
    31923 1sqd:A (1.8) BS01 FE 1.13.11.27 GO:0003868 ... P93836 15301540
    31924 1sqf:A (2.1) BS01 SAM 2.1.1.176 GO:0001510 ... P36929 14656444
    31925 1sqi:A (2.15) BS01 FE 1.13.11.27 GO:0000139 ... P32755 15301540
    31926 1sqi:A (2.15) BS02 869 1.13.11.27 GO:0000139 ... P32755 15301540 MOAD: ic50<20nM
    PDBbind: -logKd/Ki=7.70, IC50<20nM
    31927 1sqi:B (2.15) BS01 FE 1.13.11.27 GO:0000139 ... P32755 15301540
    31928 1sqi:B (2.15) BS02 869 1.13.11.27 GO:0000139 ... P32755 15301540 MOAD: ic50<20nM
    31929 1sqk:A (2.5) BS01 peptide 3.6.4.- GO:0000287 ... P68135 15163409
    31930 1sqk:A (2.5) BS02 ADP 3.6.4.- GO:0000287 ... P68135 15163409
    31931 1sqk:A (2.5) BS03 LAR 3.6.4.- GO:0000287 ... P68135 15163409
    31932 1sqm:A (2.3) BS01 ZN 3.3.2.6
    3.4.11.4
    GO:0003723 ... P09960 15078870
    31933 1sqp:C (2.7) BS01 HEC ? GO:0005739 ... P00157 15312779
    31934 1sqp:C (2.7) BS02 HEC ? GO:0005739 ... P00157 15312779
    31935 1sqp:C (2.7) BS03 MYX ? GO:0005739 ... P00157 15312779 PDBbind: -logKd/Ki=8.20, IC50=6.3nM
    31936 1sqp:E (2.7) BS01 FES 7.1.1.8 GO:0008121 ... P13272 15312779
    31937 1sqp:E (2.7) BS02 PLX 7.1.1.8 GO:0008121 ... P13272 15312779
    31938 1sqp:J (2.7) BS01 PLX 1.10.2.2 GO:0005739 ... P00130 15312779
    31939 1sqq:C (3.0) BS01 HEC ? GO:0005739 ... P00157 15312779
    31940 1sqq:C (3.0) BS02 HEC ? GO:0005739 ... P00157 15312779
    31941 1sqq:C (3.0) BS03 UQ2 ? GO:0005739 ... P00157 15312779
    31942 1sqq:C (3.0) BS04 OST ? GO:0005739 ... P00157 15312779 PDBbind: -logKd/Ki=7.82, Kd=15nM
    31943 1sqq:E (3.0) BS01 FES 7.1.1.8 GO:0008121 ... P13272 15312779
    31944 1sqv:C (2.85) BS01 HEC 1.10.2.2 GO:0005739 ... P00157 15312779
    31945 1sqv:C (2.85) BS02 HEC 1.10.2.2 GO:0005739 ... P00157 15312779
    31946 1sqv:C (2.85) BS03 UHD 1.10.2.2 GO:0005739 ... P00157 15312779
    31947 1sqv:C (2.85) BS04 UQ2 1.10.2.2 GO:0005739 ... P00157 15312779
    31948 1sqv:E (2.85) BS01 FES 7.1.1.8 GO:0008121 ... P13272 15312779
    31949 1sqx:C (2.6) BS01 UQ2 ? GO:0005739 ... P00157 15312779
    31950 1sqx:C (2.6) BS02 HEC ? GO:0005739 ... P00157 15312779
    31951 1sqx:C (2.6) BS03 HEC ? GO:0005739 ... P00157 15312779
    31952 1sqx:C (2.6) BS04 SMA ? GO:0005739 ... P00157 15312779
    31953 1sqx:E (2.6) BS01 FES 7.1.1.8 GO:0008121 ... P13272 15312779
    31954 1sqy:A (2.5) BS01 FE 3.4.21.- GO:0001503 ... P02788 N/A
    31955 1sqy:A (2.5) BS02 FE 3.4.21.- GO:0001503 ... P02788 N/A
    31956 1sqy:A (2.5) BS03 CO3 3.4.21.- GO:0001503 ... P02788 N/A
    31957 1sqy:A (2.5) BS04 CO3 3.4.21.- GO:0001503 ... P02788 N/A
    31958 1sqz:A (1.2) BS01 peptide 3.1.1.4 GO:0004623 ... P59071 N/A
    31959 1sr5:A (3.1) BS01 YYB ? GO:0002020 ... P01008 15311268
    31960 1sr5:A (3.1) BS02 U9J ? GO:0002020 ... P01008 15311268
    31961 1sr5:A (3.1) BS03 GU6 ? GO:0002020 ... P01008 15311268
    31962 1sr5:A (3.1) BS04 U9G ? GO:0002020 ... P01008 15311268
    31963 1sr6:B (2.75) BS01 MG ? GO:0005509 ... P13543 15184651
    31964 1sr6:C (2.75) BS01 CA ? GO:0005509 ... P07291 15184651
    31965 1sr9:A (2.0) BS01 ZN 2.3.3.13 GO:0000287 ... P9WQB3 15159544
    31966 1sr9:A (2.0) BS02 KIV 2.3.3.13 GO:0000287 ... P9WQB3 15159544
    31967 1sr9:B (2.0) BS01 ZN 2.3.3.13 GO:0000287 ... P9WQB3 15159544
    31968 1sr9:B (2.0) BS02 KIV 2.3.3.13 GO:0000287 ... P9WQB3 15159544
    31969 1sra:A (2.0) BS01 CA ? GO:0005509 ... P09486 8548457
    31970 1sra:A (2.0) BS02 CA ? GO:0005509 ... P09486 8548457
    31971 1sra:A (2.0) BS03 CA ? GO:0005509 ... P09486 8548457
    31972 1srn:A (1.8) BS01 peptide 4.6.1.18 GO:0003676 ... P61823 3680234
    31973 1srp:A (2.0) BS01 CA 3.4.24.40 GO:0004222 ... P07268 8797082
    31974 1srp:A (2.0) BS02 CA 3.4.24.40 GO:0004222 ... P07268 8797082
    31975 1srp:A (2.0) BS03 CA 3.4.24.40 GO:0004222 ... P07268 8797082
    31976 1srp:A (2.0) BS04 CA 3.4.24.40 GO:0004222 ... P07268 8797082
    31977 1srp:A (2.0) BS05 CA 3.4.24.40 GO:0004222 ... P07268 8797082
    31978 1srp:A (2.0) BS06 CA 3.4.24.40 GO:0004222 ... P07268 8797082
    31979 1srp:A (2.0) BS07 CA 3.4.24.40 GO:0004222 ... P07268 8797082
    31980 1srp:A (2.0) BS08 ZN 3.4.24.40 GO:0004222 ... P07268 8797082
    31981 1srr:A (1.9) BS01 CA 2.7.-.- GO:0000160 ... P06628 8805550
    31982 1srr:C (1.9) BS01 CA 2.7.-.- GO:0000160 ... P06628 8805550
    31983 1ssa:A (2.0) BS01 peptide 4.6.1.18 GO:0003676 ... P61823 8142897
    31984 1ssb:A (2.0) BS01 peptide 4.6.1.18 GO:0003676 ... P61823 8142897
    31985 1ssc:A (2.0) BS01 peptide 4.6.1.18 GO:0003676 ... P61823 15299768
    31986 1ssg:A (2.9) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P00940 15166315
    31987 1ssg:B (2.9) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P00940 15166315
    31988 1ssq:A (1.85) BS01 CYS 2.3.1.30 GO:0005737 ... P43886 15147185 MOAD: Ki=1uM
    PDBbind: -logKd/Ki=6.00, Ki=1uM
    31989 1ssq:D (1.85) BS01 CYS 2.3.1.30 GO:0005737 ... P43886 15147185
    31990 1sst:A (2.0) BS01 COA 2.3.1.30 GO:0005737 ... P43886 15147185
    31991 1sst:A (2.0) BS02 COA 2.3.1.30 GO:0005737 ... P43886 15147185
    31992 1sst:B (2.0) BS01 COA 2.3.1.30 GO:0005737 ... P43886 15147185
    31993 1sst:B (2.0) BS02 COA 2.3.1.30 GO:0005737 ... P43886 15147185
    31994 1sst:C (2.0) BS01 COA 2.3.1.30 GO:0005737 ... P43886 15147185
    31995 1sst:C (2.0) BS02 COA 2.3.1.30 GO:0005737 ... P43886 15147185
    31996 1st0:A (1.9) BS01 GTG 3.6.1.59 GO:0000288 ... Q96C86 15068804
    31997 1st0:B (1.9) BS01 GTG 3.6.1.59 GO:0000288 ... Q96C86 15068804
    31998 1st0:B (1.9) BS02 GTG 3.6.1.59 GO:0000288 ... Q96C86 15068804
    31999 1st3:A (1.4) BS01 CA 3.4.21.62 GO:0004252 ... P29599 1453465
    32000 1st3:A (1.4) BS02 CA 3.4.21.62 GO:0004252 ... P29599 1453465

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218