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BioLiP
Download all results in tab-seperated text for 594392 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    22601 1ng9:B (2.6) BS02 ADP ? GO:0000018 ... P23909 12554674
    22602 1ngk:A (2.11) BS01 CYN ? GO:0005344 ... P9WN23 12719529
    22603 1ngk:A (2.11) BS02 HEM ? GO:0005344 ... P9WN23 12719529
    22604 1ngk:B (2.11) BS01 CYN ? GO:0005344 ... P9WN23 12719529
    22605 1ngk:B (2.11) BS02 HEM ? GO:0005344 ... P9WN23 12719529
    22606 1ngk:C (2.11) BS01 CYN ? GO:0005344 ... P9WN23 12719529
    22607 1ngk:C (2.11) BS02 HEM ? GO:0005344 ... P9WN23 12719529
    22608 1ngk:D (2.11) BS01 CYN ? GO:0005344 ... P9WN23 12719529
    22609 1ngk:D (2.11) BS02 HEM ? GO:0005344 ... P9WN23 12719529
    22610 1ngk:E (2.11) BS01 CYN ? GO:0005344 ... P9WN23 12719529
    22611 1ngk:E (2.11) BS02 HEM ? GO:0005344 ... P9WN23 12719529
    22612 1ngk:F (2.11) BS01 CYN ? GO:0005344 ... P9WN23 12719529
    22613 1ngk:F (2.11) BS02 HEM ? GO:0005344 ... P9WN23 12719529
    22614 1ngk:G (2.11) BS01 CYN ? GO:0005344 ... P9WN23 12719529
    22615 1ngk:G (2.11) BS02 HEM ? GO:0005344 ... P9WN23 12719529
    22616 1ngk:H (2.11) BS01 CYN ? GO:0005344 ... P9WN23 12719529
    22617 1ngk:H (2.11) BS02 HEM ? GO:0005344 ... P9WN23 12719529
    22618 1ngk:I (2.11) BS01 CYN ? GO:0005344 ... P9WN23 12719529
    22619 1ngk:I (2.11) BS02 HEM ? GO:0005344 ... P9WN23 12719529
    22620 1ngk:J (2.11) BS01 CYN ? GO:0005344 ... P9WN23 12719529
    22621 1ngk:J (2.11) BS02 HEM ? GO:0005344 ... P9WN23 12719529
    22622 1ngk:K (2.11) BS01 CYN ? GO:0005344 ... P9WN23 12719529
    22623 1ngk:K (2.11) BS02 HEM ? GO:0005344 ... P9WN23 12719529
    22624 1ngk:L (2.11) BS01 CYN ? GO:0005344 ... P9WN23 12719529
    22625 1ngk:L (2.11) BS02 HEM ? GO:0005344 ... P9WN23 12719529
    22626 1ngs:A (2.4) BS01 CA 2.2.1.1 GO:0003824 ... P23254 8999873
    22627 1ngs:A (2.4) BS02 E4P 2.2.1.1 GO:0003824 ... P23254 8999873
    22628 1ngs:A (2.4) BS03 TPP 2.2.1.1 GO:0003824 ... P23254 8999873
    22629 1ngs:A (2.4) BS04 E4P 2.2.1.1 GO:0003824 ... P23254 8999873
    22630 1ngs:A (2.4) BS05 TPP 2.2.1.1 GO:0003824 ... P23254 8999873
    22631 1ngs:B (2.4) BS01 E4P 2.2.1.1 GO:0003824 ... P23254 8999873
    22632 1ngs:B (2.4) BS02 TPP 2.2.1.1 GO:0003824 ... P23254 8999873
    22633 1ngs:B (2.4) BS03 CA 2.2.1.1 GO:0003824 ... P23254 8999873
    22634 1ngs:B (2.4) BS04 E4P 2.2.1.1 GO:0003824 ... P23254 8999873
    22635 1ngs:B (2.4) BS05 TPP 2.2.1.1 GO:0003824 ... P23254 8999873
    22636 1ngw:B (2.6) BS01 MMP ? GO:0002250 ... P06328 12552112
    22637 1ngw:H (2.6) BS01 MMP ? GO:0002250 ... P06328 12552112
    22638 1nh2:C (1.9) BS01 dna ? GO:0005672 ... P32773 12972251
    22639 1nh2:C (1.9) BS02 dna ? GO:0005672 ... P32773 12972251
    22640 1nh3:A (3.1) BS01 dna 5.6.2.1 GO:0003677 ... P11387 12533542
    22641 1nh3:A (3.1) BS02 dna 5.6.2.1 GO:0003677 ... P11387 12533542
    22642 1nh3:A (3.1) BS03 dna 5.6.2.1 GO:0003677 ... P11387 12533542
    22643 1nh8:A (1.8) BS01 AMP 2.4.2.17 GO:0000105 ... P9WMN1 12511575
    22644 1nh8:A (1.8) BS02 HIS 2.4.2.17 GO:0000105 ... P9WMN1 12511575
    22645 1nhb:A (1.8) BS01 PYJ 3.2.1.17 GO:0003796 ... P00720 7612599 MOAD: Ka=14800M^-1
    22646 1nhc:A (1.7) BS01 GOL 3.2.1.15 GO:0004650 ... P26213 14623112
    22647 1nhc:B (1.7) BS01 MAN 3.2.1.15 GO:0004650 ... P26213 14623112
    22648 1nhc:B (1.7) BS02 GOL 3.2.1.15 GO:0004650 ... P26213 14623112
    22649 1nhc:D (1.7) BS01 MAN 3.2.1.15 GO:0004650 ... P26213 14623112
    22650 1nhc:D (1.7) BS02 GOL 3.2.1.15 GO:0004650 ... P26213 14623112
    22651 1nhc:E (1.7) BS01 BMA 3.2.1.15 GO:0004650 ... P26213 14623112
    22652 1nhc:E (1.7) BS02 MAN 3.2.1.15 GO:0004650 ... P26213 14623112
    22653 1nhc:E (1.7) BS03 MAN 3.2.1.15 GO:0004650 ... P26213 14623112
    22654 1nhc:E (1.7) BS04 GOL 3.2.1.15 GO:0004650 ... P26213 14623112
    22655 1nhc:F (1.7) BS01 MAN 3.2.1.15 GO:0004650 ... P26213 14623112
    22656 1nhc:F (1.7) BS02 GOL 3.2.1.15 GO:0004650 ... P26213 14623112
    22657 1nhe:A (2.5) BS01 CA ? GO:0004461 ... P29752 11419947
    22658 1nhe:C (2.5) BS01 CA ? GO:0004461 ... P29752 11419947
    22659 1nhh:A (2.4) BS01 ANP ? GO:0005524 ... P23367 12782329
    22660 1nhi:A (2.0) BS01 K ? GO:0005524 ... P23367 12782329
    22661 1nhi:A (2.0) BS02 ANP ? GO:0005524 ... P23367 12782329
    22662 1nhj:A (2.3) BS01 ANP ? GO:0005524 ... P23367 12782329
    22663 1nhk:L (1.9) BS01 CMP 2.7.4.6 GO:0004550 ... P15266 7783219
    22664 1nhk:R (1.9) BS01 CMP 2.7.4.6 GO:0004550 ... P15266 7783219
    22665 1nht:A (2.5) BS01 MG 6.3.4.4 GO:0000166 ... P0A7D4 9182542
    22666 1nht:A (2.5) BS02 GDP 6.3.4.4 GO:0000166 ... P0A7D4 9182542
    22667 1nht:A (2.5) BS03 HDA 6.3.4.4 GO:0000166 ... P0A7D4 9182542
    22668 1nht:A (2.5) BS04 PGS 6.3.4.4 GO:0000166 ... P0A7D4 9182542
    22669 1nhx:A (2.1) BS01 MN 2.7.11.-
    4.1.1.32
    GO:0000287 ... P35558 14552798
    22670 1nhx:A (2.1) BS02 PEP 2.7.11.-
    4.1.1.32
    GO:0000287 ... P35558 14552798
    22671 1nhx:A (2.1) BS03 FTB 2.7.11.-
    4.1.1.32
    GO:0000287 ... P35558 14552798 MOAD: ic50=2.11uM
    PDBbind: -logKd/Ki=5.68, IC50=2.11uM
    BindingDB: IC50=2110nM
    22672 1ni1:B (2.3) BS01 ZN 2.5.1.58 GO:0003824 ... Q02293 12699757
    22673 1ni1:B (2.3) BS02 HFP 2.5.1.58 GO:0003824 ... Q02293 12699757
    22674 1ni1:B (2.3) BS03 2C5 2.5.1.58 GO:0003824 ... Q02293 12699757 MOAD: ic50=0.9nM
    PDBbind: -logKd/Ki=9.05, IC50=0.90nM
    22675 1ni4:A (1.95) BS01 TPP 1.2.4.1 GO:0004738 ... P08559 12651851
    22676 1ni4:A (1.95) BS02 MG 1.2.4.1 GO:0004738 ... P08559 12651851
    22677 1ni4:B (1.95) BS01 TPP 1.2.4.1 GO:0003824 ... P11177 12651851
    22678 1ni4:C (1.95) BS01 MG 1.2.4.1 GO:0004738 ... P08559 12651851
    22679 1ni4:C (1.95) BS02 TPP 1.2.4.1 GO:0004738 ... P08559 12651851
    22680 1ni4:D (1.95) BS01 TPP 1.2.4.1 GO:0003824 ... P11177 12651851
    22681 1nia:A (2.5) BS01 CU 1.7.2.1 GO:0005507 ... P25006 7499203
    22682 1nia:A (2.5) BS02 CU 1.7.2.1 GO:0005507 ... P25006 7499203
    22683 1nia:B (2.5) BS01 CU 1.7.2.1 GO:0005507 ... P25006 7499203
    22684 1nia:B (2.5) BS02 CU 1.7.2.1 GO:0005507 ... P25006 7499203
    22685 1nia:C (2.5) BS01 CU 1.7.2.1 GO:0005507 ... P25006 7499203
    22686 1nia:C (2.5) BS02 CU 1.7.2.1 GO:0005507 ... P25006 7499203
    22687 1nib:A (2.7) BS01 CU 1.7.2.1 GO:0005507 ... P25006 7499203
    22688 1nib:A (2.7) BS02 CU 1.7.2.1 GO:0005507 ... P25006 7499203
    22689 1nib:B (2.7) BS01 CU 1.7.2.1 GO:0005507 ... P25006 7499203
    22690 1nib:B (2.7) BS02 CU 1.7.2.1 GO:0005507 ... P25006 7499203
    22691 1nib:C (2.7) BS01 CU 1.7.2.1 GO:0005507 ... P25006 7499203
    22692 1nib:C (2.7) BS02 CU 1.7.2.1 GO:0005507 ... P25006 7499203
    22693 1nic:A (1.9) BS01 CU 1.7.2.1 GO:0005507 ... P25006 7499203
    22694 1nic:A (1.9) BS02 CU 1.7.2.1 GO:0005507 ... P25006 7499203
    22695 1nid:A (2.2) BS01 CU 1.7.2.1 GO:0005507 ... P25006 7499203
    22696 1nid:A (2.2) BS02 CU 1.7.2.1 GO:0005507 ... P25006 7499203
    22697 1nid:A (2.2) BS03 NO2 1.7.2.1 GO:0005507 ... P25006 7499203
    22698 1nie:A (1.9) BS01 CU 1.7.2.1 GO:0005507 ... P25006 7499203
    22699 1nie:A (1.9) BS02 CU 1.7.2.1 GO:0005507 ... P25006 7499203
    22700 1nif:A (1.7) BS01 CU 1.7.2.1 GO:0005507 ... P25006 7499203
    22701 1nif:A (1.7) BS02 CU 1.7.2.1 GO:0005507 ... P25006 7499203
    22702 1nih:A (2.6) BS01 HNI ? GO:0004601 ... P69905 2370669
    22703 1nih:B (2.6) BS01 HEM ? GO:0004601 ... P68871 2370669
    22704 1nih:B (2.6) BS02 CMO ? GO:0004601 ... P68871 2370669
    22705 1nih:C (2.6) BS01 HNI ? GO:0004601 ... P69905 2370669
    22706 1nih:D (2.6) BS01 HEM ? GO:0004601 ... P68871 2370669
    22707 1nih:D (2.6) BS02 CMO ? GO:0004601 ... P68871 2370669
    22708 1nik:A (4.1) BS01 ZN 2.7.7.6 GO:0000428 ... P04050 12746498
    22709 1nik:B (4.1) BS01 ZN 2.7.7.6 GO:0000428 ... P08518 12746498
    22710 1nik:C (4.1) BS01 ZN 2.7.7.6 GO:0000428 ... P16370 12746498
    22711 1nik:I (4.1) BS01 ZN 2.7.7.6 GO:0000428 ... P27999 12746498
    22712 1nik:I (4.1) BS02 ZN 2.7.7.6 GO:0000428 ... P27999 12746498
    22713 1nik:J (4.1) BS01 ZN 2.7.7.6 GO:0000428 ... P22139 12746498
    22714 1nin:A (-1.00) BS01 CU ? GO:0005507 ... P0C178 8679527
    22715 1nir:A (2.15) BS01 HEC 1.7.2.1
    1.7.99.1
    GO:0009055 ... P24474 9331415
    22716 1nir:A (2.15) BS02 DHE 1.7.2.1
    1.7.99.1
    GO:0009055 ... P24474 9331415
    22717 1nir:B (2.15) BS01 HEC 1.7.2.1
    1.7.99.1
    GO:0009055 ... P24474 9331415
    22718 1nir:B (2.15) BS02 DHE 1.7.2.1
    1.7.99.1
    GO:0009055 ... P24474 9331415
    22719 1nis:A (2.05) BS01 SF4 4.2.1.3 GO:0003994 ... P20004 8151704
    22720 1nis:A (2.05) BS02 NTC 4.2.1.3 GO:0003994 ... P20004 8151704
    22721 1nit:A (2.05) BS01 SO4 4.2.1.3 GO:0003994 ... P20004 8151704
    22722 1nit:A (2.05) BS02 SF4 4.2.1.3 GO:0003994 ... P20004 8151704
    22723 1niu:A (2.2) BS01 DCS 5.1.1.1 GO:0003824 ... P10724 12741835 MOAD: Ki=0.08uM
    22724 1niu:A (2.2) BS02 DCS 5.1.1.1 GO:0003824 ... P10724 12741835 MOAD: Ki=0.08uM
    22725 1niu:B (2.2) BS01 DCS 5.1.1.1 GO:0003824 ... P10724 12741835 MOAD: Ki=0.08uM
    22726 1niu:B (2.2) BS02 DCS 5.1.1.1 GO:0003824 ... P10724 12741835 MOAD: Ki=0.08uM
    22727 1niw:A (2.05) BS01 peptide ? GO:0000086 ... P0DP29 12574113
    22728 1niw:A (2.05) BS02 CA ? GO:0000086 ... P0DP29 12574113
    22729 1niw:A (2.05) BS03 CA ? GO:0000086 ... P0DP29 12574113
    22730 1niw:A (2.05) BS04 CA ? GO:0000086 ... P0DP29 12574113
    22731 1niw:A (2.05) BS05 CA ? GO:0000086 ... P0DP29 12574113
    22732 1niw:C (2.05) BS01 peptide ? GO:0000086 ... P0DP29 12574113
    22733 1niw:C (2.05) BS02 CA ? GO:0000086 ... P0DP29 12574113
    22734 1niw:C (2.05) BS03 CA ? GO:0000086 ... P0DP29 12574113
    22735 1niw:C (2.05) BS04 CA ? GO:0000086 ... P0DP29 12574113
    22736 1niw:C (2.05) BS05 CA ? GO:0000086 ... P0DP29 12574113
    22737 1niw:E (2.05) BS01 peptide ? GO:0000086 ... P0DP29 12574113
    22738 1niw:E (2.05) BS02 CA ? GO:0000086 ... P0DP29 12574113
    22739 1niw:E (2.05) BS03 CA ? GO:0000086 ... P0DP29 12574113
    22740 1niw:E (2.05) BS04 CA ? GO:0000086 ... P0DP29 12574113
    22741 1niw:E (2.05) BS05 CA ? GO:0000086 ... P0DP29 12574113
    22742 1niw:G (2.05) BS01 peptide ? GO:0000086 ... P0DP29 12574113
    22743 1niw:G (2.05) BS02 CA ? GO:0000086 ... P0DP29 12574113
    22744 1niw:G (2.05) BS03 CA ? GO:0000086 ... P0DP29 12574113
    22745 1niw:G (2.05) BS04 CA ? GO:0000086 ... P0DP29 12574113
    22746 1niw:G (2.05) BS05 CA ? GO:0000086 ... P0DP29 12574113
    22747 1nj1:A (2.55) BS01 ZN 6.1.1.15 GO:0000166 ... O26708 12578991
    22748 1nj1:A (2.55) BS02 MG 6.1.1.15 GO:0000166 ... O26708 12578991
    22749 1nj1:A (2.55) BS03 5CA 6.1.1.15 GO:0000166 ... O26708 12578991 PDBbind: -logKd/Ki=7.60, Ki=25nM
    22750 1nj2:A (3.11) BS01 ZN 6.1.1.15 GO:0000166 ... O26708 12578991
    22751 1nj5:A (2.8) BS01 ZN 6.1.1.15 GO:0000166 ... O26708 12578991
    22752 1nj5:A (2.8) BS02 MG 6.1.1.15 GO:0000166 ... O26708 12578991
    22753 1nj5:A (2.8) BS03 P5A 6.1.1.15 GO:0000166 ... O26708 12578991 PDBbind: -logKd/Ki=7.30, Ki=50nM
    22754 1nj6:A (2.85) BS01 ZN 6.1.1.15 GO:0000166 ... O26708 12578991
    22755 1nj6:A (2.85) BS02 MG 6.1.1.15 GO:0000166 ... O26708 12578991
    22756 1nj6:A (2.85) BS03 A5A 6.1.1.15 GO:0000166 ... O26708 12578991
    22757 1nja:A (2.5) BS01 DCM 2.1.1.45 GO:0004799 ... P00469 8611496 MOAD: Kd=0.49uM
    PDBbind: -logKd/Ki=6.31, Kd=0.49uM
    22758 1njb:A (2.74) BS01 UMP 2.1.1.45 GO:0004799 ... P00469 8611496 PDBbind: -logKd/Ki=5.80, Kd=1.6uM
    22759 1njc:A (2.5) BS01 DCM 2.1.1.45 GO:0004799 ... P00469 8611496 MOAD: Kd=2.8uM
    PDBbind: -logKd/Ki=5.55, Kd=2.8uM
    22760 1njd:A (2.2) BS01 UMP 2.1.1.45 GO:0004799 ... P00469 8611496 MOAD: Kd=2.7uM
    PDBbind: -logKd/Ki=5.57, Kd=2.7uM
    22761 1nje:A (2.3) BS01 DCM 2.1.1.45 GO:0004799 ... P00469 8611496 MOAD: Kd=160uM
    PDBbind: -logKd/Ki=3.80, Kd=160uM
    22762 1njf:A (2.3) BS01 ZN 2.7.7.7 GO:0003887 ... P06710 12623013
    22763 1njf:A (2.3) BS02 AGS 2.7.7.7 GO:0003887 ... P06710 12623013 MOAD: Kd=0.62uM
    PDBbind: -logKd/Ki=6.21, Kd=0.62uM
    22764 1njf:B (2.3) BS01 ZN 2.7.7.7 GO:0003887 ... P06710 12623013
    22765 1njf:B (2.3) BS02 AGS 2.7.7.7 GO:0003887 ... P06710 12623013 MOAD: Kd=0.62uM
    22766 1njf:C (2.3) BS01 ZN 2.7.7.7 GO:0003887 ... P06710 12623013
    22767 1njf:C (2.3) BS02 ADP 2.7.7.7 GO:0003887 ... P06710 12623013 MOAD: Kd=1.03uM
    22768 1njf:D (2.3) BS01 ZN 2.7.7.7 GO:0003887 ... P06710 12623013
    22769 1njf:D (2.3) BS02 AGS 2.7.7.7 GO:0003887 ... P06710 12623013 MOAD: Kd=0.62uM
    22770 1njg:A (2.2) BS01 ZN 2.7.7.7 GO:0003887 ... P06710 12623013
    22771 1njg:B (2.2) BS01 ZN 2.7.7.7 GO:0003887 ... P06710 12623013
    22772 1nji:1 (3.0) BS01 rna ? GO:0003735 ... P60619 12860128
    22773 1nji:1 (3.0) BS02 MG ? GO:0003735 ... P60619 12860128
    22774 1nji:2 (3.0) BS01 rna ? GO:0003723 ... P32410 12860128
    22775 1nji:3 (3.0) BS01 rna ? GO:0003735 ... P22452 12860128
    22776 1nji:4 (3.0) BS01 rna ? GO:0000049 ... P32411 12860128
    22777 1nji:4 (3.0) BS02 MG ? GO:0000049 ... P32411 12860128
    22778 1nji:C (3.0) BS01 rna ? GO:0002181 ... P20276 12860128
    22779 1nji:C (3.0) BS02 MG ? GO:0002181 ... P20276 12860128
    22780 1nji:D (3.0) BS01 rna ? GO:0003723 ... P20279 12860128
    22781 1nji:E (3.0) BS01 rna ? GO:0003723 ... P12735 12860128
    22782 1nji:F (3.0) BS01 rna ? GO:0000049 ... P14124 12860128
    22783 1nji:F (3.0) BS02 rna ? GO:0000049 ... P14124 12860128
    22784 1nji:G (3.0) BS01 rna ? GO:0002181 ... P14135 12860128
    22785 1nji:H (3.0) BS01 rna ? GO:0001682 ... P12743 12860128
    22786 1nji:J (3.0) BS01 rna ? GO:0000027 ... P60617 12860128
    22787 1nji:K (3.0) BS01 rna ? GO:0003729 ... P29198 12860128
    22788 1nji:L (3.0) BS01 rna ? GO:0003735 ... P22450 12860128
    22789 1nji:M (3.0) BS01 rna ? GO:0003735 ... P12737 12860128
    22790 1nji:N (3.0) BS01 rna ? GO:0002181 ... P60618 12860128
    22791 1nji:O (3.0) BS01 rna ? GO:0000027 ... P14123 12860128
    22792 1nji:O (3.0) BS02 rna ? GO:0000027 ... P14123 12860128
    22793 1nji:P (3.0) BS01 rna ? GO:0003723 ... P12733 12860128
    22794 1nji:Q (3.0) BS01 rna ? GO:0003723 ... P14119 12860128
    22795 1nji:R (3.0) BS01 rna ? GO:0003735 ... P12734 12860128
    22796 1nji:R (3.0) BS02 rna ? GO:0003735 ... P12734 12860128
    22797 1nji:S (3.0) BS01 rna ? GO:0002181 ... P10970 12860128
    22798 1nji:T (3.0) BS01 rna ? GO:0000027 ... P12732 12860128
    22799 1nji:U (3.0) BS01 rna ? GO:0002181 ... P10972 12860128
    22800 1nji:U (3.0) BS02 MG ? GO:0002181 ... P10972 12860128

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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